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[186381_at]

Description R06B10.5 /REP_DB=WormBase Gene ID /WP=CE17203 /TR=O44873 /GB=AAK21451.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_total > 35      4grp_total > 39      6grp_cgc > 24      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 168
1 2 3 4 range
A 287.2
(3)
M 		212.6
(-2.4)
A 		204.1
(-3)
A 		208.4
(-2.7)
M 		83
B 317.6
(3)
P 		182.8
(-1.8)
A 		149.8
(-3)
A 		232.9
(-0)
P 		168
C 305.8
(3)
P 		172
(-2.3)
A 		153.7
(-3)
A 		231.8
(0.1)
A 		152
avr 303.5
(3) 		189.1
(-2.1) 		169.2
(-3) 		224.4
(-0.5) 		134

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 120
1 2 3 4 5 6 range
A 259
(0.7)
A 		295.5
(3)
A 		201.2
(-3)
A 		236.2
(-0.8)
A 		210.7
(-2.4)
A 		247.6
(-0)
M 		94
B 248.9
(1.7)
A 		257.8
(3)
A 		229
(-1.2)
A 		216.2
(-3)
A 		222.8
(-2)
M 		230.8
(-0.9)
M 		42
C 268.6
(3)
P 		268.9
(3)
A 		256.2
(2.2)
A 		212.8
(-0.6)
A 		175.3
(-3)
A 		211.9
(-0.7)
M 		94
avr 258.8
(1.7) 		274.1
(3) 		228.8
(-0.8) 		221.7
(-1.4) 		202.9
(-3) 		230.1
(-0.7) 		71
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 74
1 2 3 4 range
A 104.6
(3)
M 		46.1
(-1.7)
A 		53.4
(-1.1)
A 		30.5
(-3)
M 		74
B 101.3
(3)
P 		45.1
(-2.1)
A 		34.7
(-3)
A 		49.6
(-1.7)
P 		67
C 101.2
(3)
P 		49.5
(-2)
A 		53.6
(-1.6)
A 		39.1
(-3)
A 		62
avr 102.4
(3) 		46.9
(-2.3) 		47.2
(-2.3) 		39.7
(-3) 		63

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 62
1 2 3 4 5 6 range
A 47.7
(-2.6)
A 		105.1
(3)
A 		43.8
(-3)
A 		59.9
(-1.4)
A 		63.6
(-1.1)
A 		60.3
(-1.4)
M 		61
B 86.6
(2.3)
A 		85.8
(2.2)
A 		55.6
(-3)
A 		57.3
(-2.7)
A 		90.5
(3)
M 		86.1
(2.2)
M 		35
C 99.6
(3)
P 		82.1
(1.2)
A 		65.2
(-0.6)
A 		42.8
(-3)
A 		56.7
(-1.5)
A 		70.9
(-0)
M 		57
avr 78
(0.9) 		91
(3) 		54.9
(-2.7) 		53.3
(-3) 		70.3
(-0.3) 		72.4
(0) 		38
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 186381_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8234
Sequence Type Exemplar sequence
Representative Public ID R06B10.5 NCBI
Target Description R06B10.5 /REP_DB=WormBase Gene ID /WP=CE17203 /TR=O44873 /GB=AAK21451.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064909(11), NM_064910(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064909 NCBI Caenorhabditis elegans R06B10.5 (R06B10.5) mRNA, complete cds. 11/11 None
NM_064910 NCBI Caenorhabditis elegans TRP (transient receptor potential) channel family member (trp-2) (trp-2) mRNA, complete cds. 11/11 None
SNAP00000022060 ENSEMBL cdna:SNAP chromosome:CEL140:III:983248:1005141:1 11/11 None
GENEFINDER00000022071 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:983248:988269:1 11/11 None
R06B10.5.2 ENSEMBL cdna:known chromosome:CEL140:III:977373:988273:1 gene:R06B10.5 11/11 None
R06B10.5.3 ENSEMBL cdna:known chromosome:CEL140:III:983246:988273:1 gene:R06B10.5 11/11 None
R06B10.5.1 ENSEMBL cdna:known chromosome:CEL140:III:983248:988422:1 gene:R06B10.5 11/11 None
R06B10.4a ENSEMBL cdna:known chromosome:CEL140:III:983464:1001892:1 gene:R06B10.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
192056 2 1 NM_001027532 192408_at (11)
NM_064910 186381_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:983247-988273(+) 97.17 100.0
Public Domain and Genome References
Gene Title
Ensembl R06B10.5
R06B10.4
Entrez Gene 3564790 Entrez gene
SwissProt O44873 EMBL-EBI
WormBase CE31050 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1586604_AT similar to TBC1 domain family, member 10A cfa
CANINE_2:CFA.15436.1.A1_AT similar to TBC1 domain family, member 10A cfa
CANINE_2:CFAAFFX.19415.1.S1_AT similar to TBC1 domain family, member 10A cfa
CHICKEN:GGA.12527.1.S1_AT similar to TBC1 domain family, member 10; EBP50-PDZ interactor of 64 kD; AC004997.C22.2 gga
CHICKEN:GGAAFFX.4987.1.S1_AT similar to TBC1 domain family, member 10; EBP50-PDZ interactor of 64 kD; AC004997.C22.2 gga
HG-U133_PLUS_2:226613_AT TBC1 domain family, member 10A hs
HG-U133B:226613_AT TBC1 domain family, member 10A hs
HG-U133_PLUS_2:233528_S_AT TBC1 domain family, member 10A hs
HG-U133B:233528_S_AT TBC1 domain family, member 10A hs
HU35KSUBA:RC_AA243768_AT TBC1 domain family, member 10A hs
HU35KSUBB:RC_Z41503_R_AT TBC1 domain family, member 10A hs
HU35KSUBB:RC_Z41503_I_AT TBC1 domain family, member 10A hs
U133_X3P:HS.8003.0.S1_3P_S_AT TBC1 domain family, member 10A hs
U133_X3P:HS.4232.1.S1_3P_A_AT TBC1 domain family, member 10A hs
U133_X3P:HS.4232.0.S1_3P_X_AT TBC1 domain family, member 10A hs
U133_X3P:HS.4232.0.S1_3P_AT TBC1 domain family, member 10A hs
U133_X3P:226613_3P_AT TBC1 domain family, member 10A hs
HG-U133_PLUS_2:226133_S_AT TBC1 domain family, member 10A hs
HG-U133B:226133_S_AT TBC1 domain family, member 10A hs
HG-U95B:52049_AT TBC1 domain family, member 10A hs
HG-U95C:62574_AT TBC1 domain family, member 10A hs
U133_X3P:HS2.396963.1.S1_3P_AT TBC1 domain family, member 10A hs
HG-U133_PLUS_2:1570035_AT TBC1 domain family, member 10A hs
HG-U133_PLUS_2:244382_AT TBC1 domain family, member 10A hs
HG-U133B:244382_AT TBC1 domain family, member 10A hs
HG-U95C:54052_AT TBC1 domain family, member 10A hs
HG-U95E:86209_AT TBC1 domain family, member 10A hs
U133_X3P:HS.194444.0.A1_3P_AT TBC1 domain family, member 10A hs
MG-U74AV2:96131_AT TBC1 domain family, member 10a mm
MG-U74AV2:161791_R_AT TBC1 domain family, member 10a mm
MOE430A:1448587_AT TBC1 domain family, member 10a mm
MOUSE430A_2:1448587_AT TBC1 domain family, member 10a mm
MOUSE430_2:1448587_AT TBC1 domain family, member 10a mm
MOE430B:1445667_AT TBC1 domain family, member 10a, mRNA (cDNA clone MGC:6862 IMAGE:2650923) mm
MOUSE430_2:1445667_AT TBC1 domain family, member 10a, mRNA (cDNA clone MGC:6862 IMAGE:2650923) mm
MU19KSUBA:TC24247_AT TBC1 domain family, member 10a, mRNA (cDNA clone MGC:6862 IMAGE:2650923) mm
MU11KSUBA:D19343_RC_AT TBC1 domain family, member 10a, mRNA (cDNA clone MGC:6862 IMAGE:2650923) mm
RG-U34B:RC_AI070160_AT TBC1 domain family, member 10 (predicted) rn
RG-U34C:RC_AI179882_AT TBC1 domain family, member 10 (predicted) rn
RAE230A:1374101_AT TBC1 domain family, member 10 (predicted) rn
RAT230_2:1374101_AT TBC1 domain family, member 10 (predicted) rn
Protein Similarities
Method ID Description E-Value
blast AAK21451 Hypothetical protein R06B10.5 [Caenorhabditis elegans] ref|NP_497310.2| R06B10.5 [Caenorhabditis elegans] 0.0
blast G88391 protein R06B10.5 [imported] - Caenorhabditis elegans 0.0
blast CAE69114 Hypothetical protein CBG15140 [Caenorhabditis briggsae] 0.0
blast AAN65302 Trp (transient receptor potential) channel family protein 2, isoform a [Caenorhabditis elegans] ref|NP_497311.2| TRP (transient receptor potential) channel family member (trp-2) [Caenorhabditis elegans] emb|CAC81655.1| TRP homlogous cation channel protein [Caenorhabditis elegans] 0.0
blast AAN65303 Trp (transient receptor potential) channel family protein 2, isoform b [Caenorhabditis elegans] ref|NP_001022703.1| TRP (transient receptor potential) channel family member (trp-2) [Caenorhabditis elegans] 0.0
blast F88391 protein R06B10.4 [imported] - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 3.6E-31
Pfam IPR002110 EMBL-EBI Ankyrin 0.015
Pfam IPR002110 EMBL-EBI Ankyrin 0.043
Pfam IPR000195 EMBL-EBI RabGAP/TBC domain 1.6E-29
Pfam IPR001304 EMBL-EBI C-type lectin 5.6E-10
Pfam IPR005821 EMBL-EBI Ion transport protein 3.9E-19
Pfam IPR000195 EMBL-EBI RabGAP/TBC domain 2.7E-16
Pfam IPR000195 EMBL-EBI RabGAP/TBC domain 2.6E-6
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_497311.2 5 336-355,368-390,546-568,607-629,644-663
R06B10.4a 5 336-355,368-390,546-568,607-629,644-663
SNAP00000022060 4 565-587,600-622,778-800,837-856
Sequence
Target Sequence 
>C. ELEGANS:186381_AT
accttttcgacttgctcaaagcctggacaattctccatccggaagagggctactgtcaag
gacaggctccaattgcagcggttctcctgatgcacatgccggtccgcgacgccttctact
gttttgtgcagatctgtcataagtacctgcccgggtactacagcagtggcctggaagccg
tacaaaccgatggggatatactgacgaagttgataaaggacaggagtaaacttacctaca
gacattttaaagccaacggagtcgacccagcgttatacatgatcgagtggtttatgtgct
gcttttgccgaacactaccctggcctacagtactccgcgtatgggacatgttcctgtgcg
agggcgtcaagattctgttcaaagtggcgctggtgctactgaaattcggaattgggacgc
cgtcacagattaaacagtaccccgatatgcctgcaattgtgacccggtta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACCTTTTCGACTTGCTCAAAGCCTG 349 87 788 Antisense
CAAAGCCTGGACAATTCTCCATCCG 184 193 804 Antisense
TCCAATTGCAGCGGTTCTCCTGATG 326 587 855 Antisense
ACGCCTTCTACTGTTTTGTGCAGAT 3 91 896 Antisense
TGCCCGGGTACTACAGCAGTGGCCT 435 585 935 Antisense
AGTCGACCCAGCGTTATACATGATC 361 61 1047 Antisense
TATGTGCTGCTTTTGCCGAACACTA 600 655 1080 Antisense
GCCTACAGTACTCCGCGTATGGGAC 75 283 1110 Antisense
TGCGAGGGCGTCAAGATTCTGTTCA 412 583 1144 Antisense
TAAACAGTACCCCGATATGCCTGCA 275 639 1218 Antisense
TATGCCTGCAATTGTGACCCGGTTA 243 657 1233 Antisense
Sequence Source Affymetrix Proprietary Database