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[186319_at]

Description F52C12.1 /REP_DB=WormBase Gene ID /WP=CE19434 /TR=Q9TXV7 /GB=AAC68960.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 95      6grp_high1_10_10 > 69      4grp_highest_8_8 > 61      4grp_high_8_8 > 17      6grp_highest_nonorm > 82      6grp_total > 49      4grp_total > 30      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 257
1 2 3 4 range
A 434
(3)
P 		309
(-2.8)
P 		304.2
(-3)
P 		426.5
(2.7)
P 		130
B 406.9
(3)
P 		357.7
(1.2)
P 		240.9
(-3)
P 		326.1
(0.1)
P 		166
C 497.8
(3)
P 		306.7
(-1.9)
P 		263.7
(-3)
P 		346.6
(-0.9)
P 		234
avr 446.2
(3) 		324.5
(-1.1) 		269.6
(-3) 		366.4
(0.3) 		177

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 190
1 2 3 4 5 6 range
A 407.1
(2.1)
P 		358.9
(0.4)
P 		281.8
(-2.4)
P 		264.5
(-3)
P 		409.9
(2.2)
P 		431.1
(3)
P 		167
B 360.3
(1.6)
P 		339.5
(0.8)
P 		332.5
(0.5)
P 		241.3
(-3)
P 		348
(1.1)
P 		397.9
(3)
P 		157
C 331.7
(-0.7)
P 		337.8
(-0.4)
P 		303.8
(-1.8)
P 		275.5
(-3)
P 		419.9
(3)
P 		411.7
(2.7)
P 		144
avr 366.4
(1.2) 		345.4
(0.3) 		306
(-1.2) 		260.4
(-3) 		392.6
(2.2) 		413.6
(3) 		153
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 109
1 2 3 4 range
A 158
(3)
P 		67.1
(-2.7)
P 		79.5
(-1.9)
P 		62.4
(-3)
P 		96
B 129.8
(3)
P 		88.4
(-0.4)
P 		55.8
(-3)
P 		69.5
(-1.9)
P 		74
C 164.8
(3)
P 		88.2
(-1.3)
P 		91.9
(-1.1)
P 		58.4
(-3)
P 		106
avr 150.9
(3) 		81.2
(-1.8) 		75.7
(-2.2) 		63.4
(-3) 		88

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 93
1 2 3 4 5 6 range
A 75.1
(-1.8)
P 		127.6
(3)
P 		61.4
(-3)
P 		67.1
(-2.5)
P 		123.7
(2.6)
P 		104.9
(0.9)
P 		66
B 125.4
(1.4)
P 		113
(0.5)
P 		80.7
(-1.8)
P 		63.9
(-3)
P 		141.4
(2.5)
P 		148.4
(3)
P 		85
C 122.9
(1.9)
P 		103.1
(0.5)
P 		77.3
(-1.4)
P 		55.4
(-3)
P 		135.9
(2.9)
P 		137.8
(3)
P 		82
avr 107.8
(0.8) 		114.6
(1.4) 		73.1
(-2.1) 		62.1
(-3) 		133.7
(3) 		130.4
(2.7) 		72
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 186319_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10453
Sequence Type Exemplar sequence
Representative Public ID F52C12.1 NCBI
Target Description F52C12.1 /REP_DB=WormBase Gene ID /WP=CE19434 /TR=Q9TXV7 /GB=AAC68960.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067748(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067748 NCBI Caenorhabditis elegans F52C12.1 (F52C12.1) mRNA, complete cds. 11/11 None
SNAP00000012616 ENSEMBL cdna:SNAP chromosome:CEL140:IV:1960545:1963122:1 11/11 None
GENEFINDER00000012627 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:1960459:1963122:1 11/11 None
F52C12.1.1 ENSEMBL cdna:known chromosome:CEL140:IV:1959851:1963223:1 gene:F52C12.1 11/11 None
F52C12.1.2 ENSEMBL cdna:known chromosome:CEL140:IV:1959853:1963223:1 gene:F52C12.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:1959861-1963128(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl F52C12.1
Entrez Gene 176996 Entrez gene
SwissProt Q9TXV7 EMBL-EBI
WormBase CE19434 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:250156_AT tyrosyl-DNA phosphodiesterase-related at
CANINE_2:CFA.19445.1.S1_AT similar to tyrosyl-DNA phosphodiesterase 1 cfa
CANINE_2:CFAAFFX.26760.1.S1_S_AT similar to tyrosyl-DNA phosphodiesterase 1 cfa
DROSOPHILA_2:1626850_S_AT Tyrosyl-DNA phosophodiesterase 1 dm
DROSOPHILA_2:1624269_AT Tyrosyl-DNA phosophodiesterase 1 dm
DROSGENOME1:142430_AT Tyrosyl-DNA phosophodiesterase 1 dm
CHICKEN:GGA.16007.1.S1_AT tyrosyl-DNA phosphodiesterase 1 gga
HG-U133_PLUS_2:219715_S_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U133A:219715_S_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U133A_2:219715_S_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U95B:48865_AT tyrosyl-DNA phosphodiesterase 1 hs
HU35KSUBA:RC_AA215643_AT tyrosyl-DNA phosphodiesterase 1 hs
HU35KSUBC:RC_AA479654_AT tyrosyl-DNA phosphodiesterase 1 hs
HU35KSUBD:RC_AA489025_AT tyrosyl-DNA phosphodiesterase 1 hs
U133_X3P:G8922860_3P_S_AT tyrosyl-DNA phosphodiesterase 1 hs
U133_X3P:HS.238039.1.S2_3P_X_AT tyrosyl-DNA phosphodiesterase 1 hs
U133_X3P:HS.238039.1.S2_3P_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U133_PLUS_2:226044_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U133B:226044_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U95B:47914_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U95B:48868_G_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U95C:62470_R_AT tyrosyl-DNA phosphodiesterase 1 hs
HG-U95C:66965_AT Tyrosyl-DNA phosphodiesterase 1 hs
HG-U133_PLUS_2:240605_AT Tyrosyl-DNA phosphodiesterase 1 hs
HG-U133B:240605_AT Tyrosyl-DNA phosphodiesterase 1 hs
HG-U133_PLUS_2:240822_AT Tyrosyl-DNA phosphodiesterase 1 hs
HG-U133B:240822_AT Tyrosyl-DNA phosphodiesterase 1 hs
HG-U95D:91129_AT Tyrosyl-DNA phosphodiesterase 1 hs
U133_X3P:HS.144507.0.A1_3P_AT Tyrosyl-DNA phosphodiesterase 1 hs
U133_X3P:HS.160013.0.A1_3P_AT Tyrosyl-DNA phosphodiesterase 1 hs
MOE430A:1426492_AT tyrosyl-DNA phosphodiesterase 1 mm
MOUSE430A_2:1426492_AT tyrosyl-DNA phosphodiesterase 1 mm
MOUSE430_2:1426492_AT tyrosyl-DNA phosphodiesterase 1 mm
MG-U74BV2:106275_AT tyrosyl-DNA phosphodiesterase 1 mm
MU19KSUBC:TC36654_AT Tyrosyl-DNA phosphodiesterase 1, mRNA (cDNA clone MGC:30935 IMAGE:4018534) mm
RG-U34A:RC_AA894030_AT tyrosyl-DNA phosphodiesterase 1 (predicted) rn
RAE230A:1377137_AT tyrosyl-DNA phosphodiesterase 1 (predicted) rn
RAT230_2:1377137_AT tyrosyl-DNA phosphodiesterase 1 (predicted) rn
Protein Similarities
Method ID Description E-Value
blast AAC68960 Hypothetical protein F52C12.1 [Caenorhabditis elegans] ref|NP_500149.1| F52C12.1 [Caenorhabditis elegans] sp|Q9TXV7|TYDP_CAEEL Probable tyrosyl-DNA phosphodiesterase (Tyr-DNA phosphodiesterase) 0.0
blast CAE74695 Hypothetical protein CBG22509 [Caenorhabditis briggsae] 0.0
blast CAE74695 Hypothetical protein CBG22509 [Caenorhabditis briggsae] 1.0E-160
blast CAE74695 Hypothetical protein CBG22509 [Caenorhabditis briggsae] 1.0E-158
Protein Domains
Database ID Description E-Value
Pfam IPR010347 EMBL-EBI Tyrosyl-DNA phosphodiesterase 1.0E-126
Pfam IPR010347 EMBL-EBI Tyrosyl-DNA phosphodiesterase 1.0E-126
Pfam IPR010347 EMBL-EBI Tyrosyl-DNA phosphodiesterase 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:186319_AT
ggctcaatgcagctcaattggctcactaggatctgctccaatcaactggtttcgcgggca
atttctgcagagcctcgaaggagcaaatccgtcgccgaagcaaaagcccgcgaaaatgta
tttagtgtttccgagtgttgaggatgttcggacgagttgtcagggttatgcgggtggatg
ttctgtgccgtatcgcaatagtgtgcatgctcgtcaaaaatggctgcaaggcaacatgtg
caaatggcgctccaatgcgaaacgaaggacgaacgcagtgccccactgcaagacctatgt
gaaatatgacaagaaagtggcgatttggcaattgctgaccagtgccaatttatcgaaagc
cgcgtggggagaagtgtcgttcaataaatcgaaaaacgtagagcaactaatgatccgctc
atgggaaatgggtgttcttatcactgatccaagccgtttcaatattccattcgactaccc
actggtaccgtattcggccaccgatgagccatttgtgacc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGCTCAATGCAGCTCAATTGGCTCA 638 537 795 Antisense
AATTGGCTCACTAGGATCTGCTCCA 650 179 810 Antisense
GCTCCAATCAACTGGTTTCGCGGGC 592 293 829 Antisense
CGCGGGCAATTTCTGCAGAGCCTCG 605 253 847 Antisense
GATGTTCTGTGCCGTATCGCAATAG 142 411 971 Antisense
GGCAACATGTGCAAATGGCGCTCCA 700 533 1024 Antisense
TGCCCCACTGCAAGACCTATGTGAA 544 585 1073 Antisense
TGCTGACCAGTGCCAATTTATCGAA 556 581 1127 Antisense
TATCACTGATCCAAGCCGTTTCAAT 220 659 1233 Antisense
GTTTCAATATTCCATTCGACTACCC 357 449 1250 Antisense
GGCCACCGATGAGCCATTTGTGACC 571 543 1290 Antisense
Sequence Source Affymetrix Proprietary Database