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[186245_at] 7TM receptor, sre family

Description Y39C12A.7 /REP_DB=WormBase Gene ID /WP=CE24235 /TR=Q9U2L3 /GB=CAB60493.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation
Cluster 6grp_total > 26      4grp_total > 03      6grp_cgc > 14      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 212
1 2 3 4 range
A 53.7
(-1.7)
A 		7.1
(-3)
A 		8.8
(-3)
A 		216.1
(3)
P 		209
B 36.3
(-2)
A 		5.8
(-2.9)
A 		3.9
(-3)
A 		189.2
(3)
P 		185
C 16.3
(-2.5)
A 		4.7
(-3)
A 		7.2
(-2.9)
A 		154.8
(3)
P 		150
avr 35.4
(-2) 		5.9
(-3) 		6.6
(-3) 		186.7
(3) 		181

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 84
1 2 3 4 5 6 range
A 35.1
(3)
A 		25.8
(1.2)
A 		28.4
(1.7)
A 		4.8
(-3)
A 		20.2
(0)
A 		25.1
(1)
A 		30
B 79.2
(3)
A 		45
(0.3)
A 		7.2
(-2.6)
A 		2.6
(-3)
A 		5.2
(-2.8)
A 		12.9
(-2.2)
A 		77
C 35.6
(-0.6)
A 		86.9
(3)
A 		4.6
(-2.9)
A 		21.3
(-1.7)
A 		2.5
(-3)
A 		30
(-1)
A 		84
avr 50
(2.6) 		52.6
(3) 		13.4
(-2.4) 		9.6
(-3) 		9.3
(-3) 		22.7
(-1.1) 		43
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 39
1 2 3 4 range
A 19.6
(0.6)
A 		1.5
(-3)
A 		2.3
(-2.8)
A 		31.6
(3)
P 		30
B 11.6
(-1.4)
A 		1.4
(-2.9)
A 		0.9
(-3)
A 		40.3
(3)
P 		39
C 5.4
(-2)
A 		1.3
(-3)
A 		2.5
(-2.7)
A 		26.1
(3)
P 		25
avr 12.2
(-0.9) 		1.4
(-3) 		1.9
(-2.9) 		32.7
(3) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 27
1 2 3 4 5 6 range
A 6.5
(1)
A 		9.2
(3)
A 		6.2
(0.8)
A 		1.2
(-3)
A 		6.1
(0.7)
A 		6.1
(0.7)
A 		8
B 27.6
(3)
A 		15
(0.2)
A 		1.7
(-2.8)
A 		0.7
(-3)
A 		2.1
(-2.7)
A 		4.8
(-2.1)
A 		27
C 13.2
(-0.1)
A 		26.5
(3)
A 		1.2
(-2.9)
A 		4.3
(-2.2)
A 		0.8
(-3)
A 		10
(-0.9)
A 		26
avr 15.8
(2.6) 		16.9
(3) 		3
(-2.6) 		2.1
(-3) 		3
(-2.6) 		7
(-1) 		15
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 186245_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10210
Sequence Type Exemplar sequence
Representative Public ID Y39C12A.7 NCBI
Target Description Y39C12A.7 /REP_DB=WormBase Gene ID /WP=CE24235 /TR=Q9U2L3 /GB=CAB60493.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069924(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069924 NCBI Caenorhabditis elegans Serpentine Receptor, class E (epsilon) family member (sre-15) (sre-15) mRNA, complete cds. 11/11 None
GENEFINDER00000019631 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:12240202:12252619:-1 11/11 None
Y39C12A.7 ENSEMBL cdna:known chromosome:CEL140:IV:12241334:12244007:-1 gene:Y39C12A.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:12241339-12243183(-) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor, sre family
Gene Symbol sre-15
Ensembl Y39C12A.7
Entrez Gene 189749 Entrez gene
SwissProt Q9U2L3 EMBL-EBI
WormBase CE38119 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB60492 Hypothetical protein Y39C12A.8 [Caenorhabditis elegans] ref|NP_502326.1| DNaJ domain (prokaryotic heat shock protein) family member (dnj-26) [Caenorhabditis elegans] 1.0E-170
blast CAB60493 Hypothetical protein Y39C12A.7 [Caenorhabditis elegans] ref|NP_502325.2| Serpentine Receptor, class E (epsilon) family member (sre-15) [Caenorhabditis elegans] 1.0E-144
blast CAE62209 Hypothetical protein CBG06259 [Caenorhabditis briggsae] 1.0E-108
blast CAB60493 Hypothetical protein Y39C12A.7 [Caenorhabditis elegans] ref|NP_502325.2| Serpentine Receptor, class E (epsilon) family member (sre-15) [Caenorhabditis elegans] 1.0E-100
blast CAE62209 Hypothetical protein CBG06259 [Caenorhabditis briggsae] 4.0E-86
blast NP_502328 Serpentine Receptor, class E (epsilon) family member (sre-14) [Caenorhabditis elegans] gb|AAB97543.2| Hypothetical protein C42C1.1 [Caenorhabditis elegans] 1.0E-39
Protein Domains
Database ID Description E-Value
scop a.2.3.Chaperone J-domain All alpha proteins; Long alpha-hairpin; Chaperone J-domain; Chaperone J-domain 1.00000001954148E-24
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 5.8E-20
Pfam IPR001623 EMBL-EBI Heat shock protein DnaJ, N-terminal 1.4E-26
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 6.2E-16
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_502325.2 4 76-98,103-125,159-181,191-213
Y39C12A.7 4 76-98,103-125,159-181,191-213
GENEFINDER00000019631 8 255-277,292-314,326-348,363-385,405-427,432-454,488-510,520-542
Sequence
Target Sequence 
>C. ELEGANS:186245_AT
atctcatctcaattatatccgttcttgtctgcacacaattctcgacaacattctatccat
ttcttgtattattcatgagcaatatcattagctacattgtaaatataattaactacaaac
tgaatcgctactactacaattgctcacttcgaaaattacatacgtattcgctgacggaac
gttaccaaatttcagaaaacattcaatttgccaaattcttccacatatttgccttaacgg
ttgctgtttttgccacagtttgctcacttctcctgatgctcaccagcttgtcatttactg
cctcggaaaagaatatttttctactctcttttgatacaatctacacaattttcattctag
tctgtccgtaccttcattataaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCTCATCTCAATTATATCCGTTCT 142 33 122 Antisense
GTTCTTGTCTGCACACAATTCTCGA 220 445 142 Antisense
TCTCGACAACATTCTATCCATTTCT 50 611 161 Antisense
CTACTACTACAATTGCTCACTTCGA 161 227 249 Antisense
GTATTCGCTGACGGAACGTTACCAA 561 449 285 Antisense
ATTCTTCCACATATTTGCCTTAACG 549 11 336 Antisense
GCCTTAACGGTTGCTGTTTTTGCCA 139 265 352 Antisense
GCTCACCAGCTTGTCATTTACTGCC 522 301 399 Antisense
GAATATTTTTCTACTCTCTTTTGAT 662 325 432 Antisense
AATTTTCATTCTAGTCTGTCCGTAC 341 175 468 Antisense
GTCTGTCCGTACCTTCATTATAAAA 531 471 481 Antisense
Sequence Source Affymetrix Proprietary Database