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[185840_at]

Description K11G12.6 /REP_DB=WormBase Gene ID /WP=CE02828 /TR=Q21435 /GB=AAC46571.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 54      6grp_high1_10_10 > 34      4grp_highest_8_8 > 08      4grp_high_8_8 > 53      6grp_highest_nonorm > 74      6grp_total > 01      4grp_total > 51      6grp_high1_sub > 02      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 468
1 2 3 4 range
A 576.3
(-0.2)
P 		695.9
(2.1)
P 		740.1
(3)
P 		435.8
(-3)
P 		304
B 540.8
(-1.5)
P 		832.1
(3)
P 		620.3
(-0.3)
P 		443.2
(-3)
P 		389
C 576.1
(0.3)
P 		745.1
(3)
P 		651.1
(1.5)
P 		364.3
(-3)
P 		381
avr 564.4
(-0.4) 		757.7
(3) 		670.5
(1.5) 		414.4
(-3) 		343

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 269
1 2 3 4 5 6 range
A 573.1
(-1.9)
P 		787.4
(3)
P 		564.4
(-2.1)
P 		525.2
(-3)
P 		593.4
(-1.4)
P 		649.3
(-0.2)
P 		262
B 665.9
(1)
P 		700.1
(3)
P 		636.9
(-0.6)
P 		595.3
(-3)
P 		651.5
(0.2)
P 		664.4
(1)
P 		105
C 591.7
(-0.9)
P 		711.8
(2.6)
P 		707.8
(2.5)
P 		518.6
(-3)
P 		726.4
(3)
P 		668.7
(1.3)
P 		208
avr 610.2
(-0.9) 		733.1
(3) 		636.4
(-0.1) 		546.4
(-3) 		657.1
(0.6) 		660.8
(0.7) 		187
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 166
1 2 3 4 range
A 209.8
(3)
P 		151.1
(0.6)
P 		193.5
(2.3)
P 		63.8
(-3)
P 		146
B 172.5
(1.2)
P 		205.5
(3)
P 		143.7
(-0.3)
P 		94.5
(-3)
P 		111
C 190.7
(1.7)
P 		214.2
(2.5)
P 		226.9
(3)
P 		61.4
(-3)
P 		166
avr 191
(3) 		190.3
(3) 		188
(2.8) 		73.2
(-3) 		118

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 176
1 2 3 4 5 6 range
A 105.7
(-3)
P 		280
(3)
P 		122.9
(-2.4)
P 		133.2
(-2.1)
P 		179.1
(-0.5)
P 		158.1
(-1.2)
P 		174
B 231.7
(1.2)
P 		233
(1.3)
P 		154.7
(-3)
P 		157.7
(-2.8)
P 		264.7
(3)
P 		247.7
(2.1)
P 		110
C 219.3
(2.3)
P 		217.2
(2.2)
P 		180.1
(0.5)
P 		104.3
(-3)
P 		235.1
(3)
P 		223.8
(2.5)
P 		131
avr 185.6
(-0.1) 		243.4
(3) 		152.6
(-1.9) 		131.7
(-3) 		226.3
(2.1) 		209.9
(1.2) 		112
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 185840_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16024
Sequence Type Exemplar sequence
Representative Public ID K11G12.6 NCBI
Target Description K11G12.6 /REP_DB=WormBase Gene ID /WP=CE02828 /TR=Q21435 /GB=AAC46571.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076733(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076733 NCBI Caenorhabditis elegans K11G12.6 (K11G12.6) mRNA, complete cds. 11/11 None
SNAP00000013742 ENSEMBL cdna:SNAP chromosome:CEL140:X:6723945:6729610:-1 11/11 None
GENEFINDER00000013744 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:6723945:6729610:-1 11/11 None
K11G12.6 ENSEMBL cdna:known chromosome:CEL140:X:6725738:6728859:-1 gene:K11G12.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6725876-6729789(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl K11G12.6
Entrez Gene 180941 Entrez gene
SwissProt Q21435 EMBL-EBI
WormBase CE34339 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.1788.1.S1_S_AT similar to K11G12.6 cfa
CANINE_2:CFAAFFX.1791.1.S1_S_AT similar to K11G12.6 cfa
CHICKEN:GGAAFFX.12038.1.S1_AT similar to MGC53562 protein gga
HG-U95AV2:31837_AT hypothetical protein BC002942 hs
HG-U133A_2:31837_AT hypothetical protein BC002942 hs
HG-U133_PLUS_2:31837_AT hypothetical protein BC002942 hs
HG-U133A:31837_AT hypothetical protein BC002942 hs
HUGENEFL:U62317_RNA7_AT hypothetical protein BC002942 hs
U133_X3P:HS.150540.0.S1_3P_S_AT hypothetical protein BC002942 hs
HG-U133A_2:212682_S_AT hypothetical protein BC002942 hs
HG-U133_PLUS_2:212682_S_AT hypothetical protein BC002942 hs
HG-U133A:212682_S_AT hypothetical protein BC002942 hs
MG-U74BV2:111426_AT expressed sequence AI451006 mm
MOE430B:1454619_AT expressed sequence AI451006 mm
MOUSE430_2:1454619_AT expressed sequence AI451006 mm
MG-U74CV2:166571_R_AT Expressed sequence AI451006, mRNA (cDNA clone MGC:90911 IMAGE:6403184) mm
MU19KSUBC:TC36283_AT Expressed sequence AI451006, mRNA (cDNA clone MGC:90911 IMAGE:6403184) mm
RAE230A:1389209_AT similar to hypothetical protein BC002942 (predicted) rn
RAT230_2:1389209_AT similar to hypothetical protein BC002942 (predicted) rn
Protein Similarities
Method ID Description E-Value
blast AAC46571 Hypothetical protein K11G12.6 [Caenorhabditis elegans] ref|NP_509134.2| K11G12.6 [Caenorhabditis elegans] 0.0
blast CAE65782 Hypothetical protein CBG10877 [Caenorhabditis briggsae] 0.0
blast CAE65782 Hypothetical protein CBG10877 [Caenorhabditis briggsae] 1.0E-170
blast AAC46570 Hypothetical protein K11G12.5 [Caenorhabditis elegans] ref|NP_509133.1| K11G12.5 [Caenorhabditis elegans] emb|CAA53720.1| Oxoglutarate/malate carrier protein [Caenorhabditis elegans] 1.0E-121
Protein Domains
Database ID Description E-Value
Pfam IPR009613 EMBL-EBI Protein of unknown function DUF1222 2.5E-42
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.7E-14
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-23
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-24
Pfam IPR009613 EMBL-EBI Protein of unknown function DUF1222 2.5E-42
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.7E-14
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-23
Pfam IPR001993 EMBL-EBI Mitochondrial substrate carrier 1.5E-24
Pfam IPR009613 EMBL-EBI Protein of unknown function DUF1222 2.5E-42
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509134.2 6 25-44,96-118,128-150,157-176,207-229,242-264
K11G12.6 6 25-44,96-118,128-150,157-176,207-229,242-264
SNAP00000013742 9 13-35,78-100,113-135,155-174,226-248,258-280,287-306,337-359,372-394
GENEFINDER00000013744 9 13-35,69-91,104-126,146-165,217-239,249-271,278-297,328-350,363-385
Sequence
Target Sequence 
>C. ELEGANS:185840_AT
gtccaagatttatttctcctcaccatccgcgtcttgatatgcaaatgtactatgctgccg
aaggaacatatcagcaaaatccgttctttctgtcacttgtctatcatcttatgcagaaca
caacggaagttgtaaatttgattgaagattatccattcaaaaatcgatcagagccgatga
gatttgcgcgtgccaagctctacatgtaccacttcactgatatcggagacaaaaactggt
ggacccgcagcttccaagaagagtacatgccgacctttaacaaaggaaatgacgctcttc
tcaactatctcaccgagcacaaaatcattaacaaaaggaaaagtgaattcgttaacggtc
ctcttggaaagtatctgaaacagtgccaccgtcttacagccgggatcgacgagatcgcct
tgatctccacaatggttgt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTCCAAGATTTATTTCTCCTCACCA 296 477 1952 Antisense
TCAGCAAAATCCGTTCTTTCTGTCA 674 623 2022 Antisense
GTCACTTGTCTATCATCTTATGCAG 501 465 2043 Antisense
AGAGCCGATGAGATTTGCGCGTGCC 72 71 2121 Antisense
CTCTACATGTACCACTTCACTGATA 691 229 2149 Antisense
CAAAAACTGGTGGACCCGCAGCTTC 467 189 2181 Antisense
GAGTACATGCCGACCTTTAACAAAG 68 399 2212 Antisense
AGGAAATGACGCTCTTCTCAACTAT 638 53 2235 Antisense
TTCTCAACTATCTCACCGAGCACAA 539 691 2249 Antisense
TGAAACAGTGCCACCGTCTTACAGC 404 571 2327 Antisense
TCGCCTTGATCTCCACAATGGTTGT 154 599 2366 Antisense
Sequence Source Affymetrix Proprietary Database