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[185312_at]

Description C52E12.4 /REP_DB=WormBase Gene ID /WP=CE06969 /TR=Q18780 /GB=AAA93455.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 51      6grp_high1_10_10 > 25      4grp_highest_8_8 > 52      4grp_high_8_8 > 16      6grp_highest_nonorm > 40      6grp_total > 25      4grp_total > 39      6grp_highest_sub > De      6grp_high1_sub > 01_02      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 501
1 2 3 4 range
A 828.7
(3)
P 		462.2
(-3)
P 		496.6
(-2.4)
P 		598
(-0.8)
P 		367
B 627
(3)
P 		478.2
(0)
P 		327.9
(-3)
P 		558.8
(1.6)
P 		299
C 730.3
(3)
P 		452.5
(-3)
P 		535.8
(-1.2)
P 		496.8
(-2)
P 		278
avr 728.7
(3) 		464.3
(-2.8) 		453.4
(-3) 		551.2
(-0.9) 		275

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 375
1 2 3 4 5 6 range
A 764
(2.6)
P 		791.2
(3)
P 		416.2
(-3)
P 		613
(0.1)
P 		503.1
(-1.6)
P 		558.7
(-0.7)
P 		375
B 765.6
(3)
P 		669.6
(1.3)
P 		458.2
(-2.5)
P 		628.2
(0.6)
P 		427.9
(-3)
P 		471.5
(-2.2)
P 		338
C 743.4
(2.6)
P 		688
(1.4)
P 		764.1
(3)
P 		526.7
(-2)
P 		478.6
(-3)
P 		573.9
(-1)
P 		286
avr 757.7
(3) 		716.3
(2.1) 		546.2
(-1.4) 		589.3
(-0.5) 		469.9
(-3) 		534.7
(-1.6) 		288
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 226
1 2 3 4 range
A 301.7
(3)
P 		100.3
(-2.6)
P 		129.8
(-1.8)
P 		87.5
(-3)
P 		214
B 199.9
(3)
P 		118.1
(-1)
P 		76
(-3)
P 		119.1
(-0.9)
P 		124
C 241.7
(3)
P 		130.1
(-1.2)
P 		186.7
(0.9)
P 		83.8
(-3)
P 		158
avr 247.8
(3) 		116.2
(-2.2) 		130.8
(-1.6) 		96.8
(-3) 		151

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 191
1 2 3 4 5 6 range
A 140.8
(-1.4)
P 		281.4
(3)
P 		90.6
(-3)
P 		155.5
(-1)
P 		151.8
(-1.1)
P 		136
(-1.6)
P 		191
B 266.4
(3)
P 		222.9
(1.3)
P 		111.3
(-3)
P 		166.4
(-0.9)
P 		173.9
(-0.6)
P 		175.8
(-0.5)
P 		155
C 275.6
(3)
P 		209.9
(0.7)
P 		194.5
(0.1)
P 		105.9
(-3)
P 		154.9
(-1.3)
P 		192.1
(0)
P 		170
avr 227.6
(2.4) 		238.1
(3) 		132.1
(-3) 		142.6
(-2.4) 		160.2
(-1.4) 		168
(-1) 		106
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 185312_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5457
Sequence Type Exemplar sequence
Representative Public ID C52E12.4 NCBI
Target Description C52E12.4 /REP_DB=WormBase Gene ID /WP=CE06969 /TR=Q18780 /GB=AAA93455.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063036(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063036 NCBI Caenorhabditis elegans C52E12.4 (C52E12.4) mRNA, complete cds. 11/11 None
SNAP00000036565 ENSEMBL cdna:SNAP chromosome:CEL140:II:7013144:7020050:-1 11/11 None
GENEFINDER00000036570 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:7013144:7015750:-1 11/11 None
C52E12.4 ENSEMBL cdna:known chromosome:CEL140:II:7012733:7022440:-1 gene:C52E12.4 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:7013139-7019828(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl C52E12.4
Entrez Gene 174146 Entrez gene
SwissProt Q18780 EMBL-EBI
WormBase CE31684 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1596981_AT similar to RAB6 interacting protein 1 cfa
CANINE_2:CFA.19640.1.S1_S_AT similar to RAB6 interacting protein 1 cfa
CANINE_2:CFAAFFX.11711.1.S1_S_AT similar to RAB6 interacting protein 1 cfa
DROSOPHILA_2:1623043_S_AT dm
DROSGENOME1:147985_AT dm
CHICKEN:GGAAFFX.26626.1.S1_AT similar to RAB6 interacting protein 1 gga
CHICKEN:GGAAFFX.26626.2.S1_S_AT similar to RAB6 interacting protein 1 gga
CHICKEN:GGAAFFX.3650.1.S1_S_AT similar to RAB6 interacting protein 1 gga
HU35KSUBA:RC_AA022884_AT RAB6 interacting protein 1 hs
HU35KSUBD:RC_AA349595_AT RAB6 interacting protein 1 hs
U133_X3P:HS.26797.0.S1_3P_AT RAB6 interacting protein 1 hs
HG-U133A_2:212561_AT RAB6 interacting protein 1 hs
HG-U133_PLUS_2:212561_AT RAB6 interacting protein 1 hs
HG-U133A:212561_AT RAB6 interacting protein 1 hs
HG-U95AV2:33924_AT RAB6 interacting protein 1 hs
HG-U95E:82391_AT RAB6 interacting protein 1 hs
MU11KSUBA:C79507_RC_F_AT Rab6 interacting protein 1 mm
MU11KSUBA:AA259973_S_AT Rab6 interacting protein 1 mm
MG-U74AV2:104108_AT Rab6 interacting protein 1 mm
MOE430A:1424015_AT Rab6 interacting protein 1 mm
MOUSE430A_2:1424015_AT Rab6 interacting protein 1 mm
MOUSE430_2:1424015_AT Rab6 interacting protein 1 mm
MU19KSUBC:TC41036_AT Rab6 interacting protein 1, mRNA (cDNA clone MGC:37737 IMAGE:5067385) mm
RAE230A:1373375_AT Rab6 interacting protein 1 (predicted) rn
RAT230_2:1373375_AT Rab6 interacting protein 1 (predicted) rn
RG-U34C:RC_AA819350_AT Rab6 interacting protein 1 (predicted) rn
RG-U34C:H31373_AT Rab6 interacting protein 1 (predicted) rn
RAE230B:1383038_AT Rab6 interacting protein 1 (predicted) rn
RAT230_2:1383038_AT Rab6 interacting protein 1 (predicted) rn
RG-U34C:RC_AI072148_AT Rab6 interacting protein 1 (predicted) rn
Protein Similarities
Method ID Description E-Value
blast AAA93455 Hypothetical protein C52E12.4 [Caenorhabditis elegans] ref|NP_495437.2| C52E12.4 [Caenorhabditis elegans] 0.0
blast CAE66012 Hypothetical protein CBG11204 [Caenorhabditis briggsae] 0.0
blast EAA05180 ENSANGP00000008188 [Anopheles gambiae str. PEST] ref|XP_309299.2| ENSANGP00000008188 [Anopheles gambiae str. PEST] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005112 EMBL-EBI dDENN domain 1.3E-31
Pfam IPR001194 EMBL-EBI DENN (AEX-3) domain 1.9E-43
Pfam IPR001024 EMBL-EBI Lipoxygenase, LH2 domain 6.0E-21
Pfam IPR004012 EMBL-EBI RUN domain 7.5E-23
Pfam IPR005112 EMBL-EBI dDENN domain 1.3E-31
Pfam IPR001194 EMBL-EBI DENN (AEX-3) domain 4.4E-37
Pfam IPR001024 EMBL-EBI Lipoxygenase, LH2 domain 6.0E-21
Pfam IPR004012 EMBL-EBI RUN domain 7.5E-23
Pfam IPR001024 EMBL-EBI Lipoxygenase, LH2 domain 6.0E-21
Pfam IPR004012 EMBL-EBI RUN domain 4.8E-22
Sequence
Target Sequence 
>C. ELEGANS:185312_AT
gagctctagaagccaaacaccgcagagggagcgaagtccatcgaatggtcgaatggcaga
atctagttcaaggaatagaaagacaaaagtcagtgaggttgagcatcttcttggtgaagc
agtaaatgccctggtcaagtatttctgctcagaacgaaaagtgaaaagcgagttagctca
cttgttgtgtggacagaaaggtctcgtgctggcaattgaacaagcattccagctgggtag
acaagaatctctactcaaatattttagaaacacttgtccgtgggattatattgaacgagt
atgctcatggtttttcgaactctgcaggaaaaaagaagttgacaagttaccaaaagagca
gaagacaatgattcatcatgcattgagagatcatattcttcctggactgcttccattaat
gcgatactcccctgtaaccgccgacatgtacaatgaaccatcatttcttcgaactcctgc
tcatatgactta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGCTCTAGAAGCCAAACACCGCAG 415 387 3162 Antisense
GTGAGGTTGAGCATCTTCTTGGTGA 247 483 3254 Antisense
TGCCCTGGTCAAGTATTTCTGCTCA 441 583 3288 Antisense
AAGCGAGTTAGCTCACTTGTTGTGT 115 149 3327 Antisense
GACAGAAAGGTCTCGTGCTGGCAAT 701 365 3353 Antisense
GCTCATGGTTTTTCGAACTCTGCAG 451 301 3464 Antisense
GATCATATTCTTCCTGGACTGCTTC 243 421 3550 Antisense
TGCTTCCATTAATGCGATACTCCCC 291 579 3569 Antisense
GTAACCGCCGACATGTACAATGAAC 695 461 3595 Antisense
TGAACCATCATTTCTTCGAACTCCT 62 575 3615 Antisense
TTCGAACTCCTGCTCATATGACTTA 333 695 3629 Antisense
Sequence Source Affymetrix Proprietary Database