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[185034_s_at]

Description T23B12.6 /REP_DB=WormBase Gene ID /WP=CE14036 /TR=O17001 /GB=AAB69932.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 88      6grp_high1_10_10 > 97      4grp_highest_8_8 > 43      4grp_high_8_8 > 48      6grp_highest_nonorm > 83      6grp_total > 96      4grp_total > 55      6grp_highest_sub > Da      6grp_high1_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 216
1 2 3 4 range
A 385.9
(3)
P 		298.2
(-2.8)
P 		351.7
(0.7)
P 		295.4
(-3)
P 		91
B 414.9
(3)
P 		231.8
(-3)
P 		272.6
(-1.7)
P 		322.7
(-0)
P 		183
C 402
(3)
P 		264.7
(-1.1)
P 		314.5
(0.4)
P 		199
(-3)
P 		203
avr 400.9
(3) 		264.9
(-3) 		312.9
(-0.9) 		272.4
(-2.7) 		136

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 255
1 2 3 4 5 6 range
A 362.6
(-1.3)
P 		426.2
(0.8)
P 		310.4
(-3)
P 		482.2
(2.6)
P 		459.6
(1.8)
P 		495
(3)
P 		185
B 378.3
(-3)
P 		419.2
(-1.5)
P 		411.4
(-1.8)
P 		414.2
(-1.7)
P 		436.8
(-0.9)
P 		543.2
(3)
P 		165
C 461.4
(-0.4)
P 		379.6
(-3)
P 		453.6
(-0.6)
P 		457.6
(-0.5)
P 		507.4
(1.1)
P 		565.5
(3)
P 		186
avr 400.8
(-2.6) 		408.3
(-2.3) 		391.8
(-3) 		451.3
(-0.5) 		467.9
(0.2) 		534.6
(3) 		143
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 107
1 2 3 4 range
A 140.5
(3)
P 		64.7
(-1.7)
P 		91.9
(0)
P 		43.2
(-3)
P 		97
B 132.3
(3)
P 		57.3
(-3)
P 		63.2
(-2.5)
P 		68.8
(-2.1)
P 		75
C 133.1
(3)
P 		76.1
(-0.4)
P 		109.6
(1.6)
P 		33.5
(-3)
P 		100
avr 135.3
(3) 		66
(-1.8) 		88.2
(-0.3) 		48.5
(-3) 		87

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 136
1 2 3 4 5 6 range
A 66.8
(-3)
P 		151.6
(3)
P 		67.6
(-2.9)
P 		122.3
(0.9)
P 		138.7
(2.1)
P 		120.5
(0.8)
P 		85
B 131.6
(-1.1)
P 		139.5
(-0.7)
P 		99.9
(-3)
P 		109.7
(-2.4)
P 		177.5
(1.5)
P 		202.6
(3)
P 		103
C 171
(1.9)
P 		115.8
(-1.5)
P 		115.5
(-1.6)
P 		92
(-3)
P 		164.2
(1.5)
P 		189.3
(3)
P 		97
avr 123.1
(-0.7) 		135.6
(0.2) 		94.3
(-3) 		108
(-1.9) 		160.1
(2.2) 		170.8
(3) 		77
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 185034_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11378
Sequence Type Exemplar sequence
Representative Public ID T23B12.6 NCBI
Target Description T23B12.6 /REP_DB=WormBase Gene ID /WP=CE14036 /TR=O17001 /GB=AAB69932.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072776(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_072776 NCBI Caenorhabditis elegans T23B12.6 (T23B12.6) mRNA, complete cds. 11/11 None
SNAP00000041999 ENSEMBL cdna:SNAP chromosome:CEL140:V:8460339:8463004:-1 11/11 None
GENEFINDER00000042020 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:8460339:8463004:-1 11/11 None
T23B12.6 ENSEMBL cdna:known chromosome:CEL140:V:8460218:8463008:-1 gene:T23B12.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:8460339-8463005(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl T23B12.6
Entrez Gene 179226 Entrez gene
SwissProt O17001 EMBL-EBI
WormBase CE14036 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.19368.1.S1_S_AT similar to potassium channel tetramerisation domain containing 3 cfa
CANINE_2:CFA.20833.1.S1_S_AT similar to potassium channel tetramerisation domain containing 3 cfa
DROSOPHILA_2:1632306_AT dm
DROSGENOME1:152624_AT dm
CHICKEN:GGA.11487.1.S1_S_AT similar to potassium channel tetramerisation domain containing 3; NY-REN-45 antigen gga
CHICKEN:GGA.16230.1.S1_AT similar to potassium channel tetramerisation domain containing 3; NY-REN-45 antigen gga
CHICKEN:GGA.16230.2.S1_A_AT similar to potassium channel tetramerisation domain containing 3; NY-REN-45 antigen gga
CHICKEN:GGAAFFX.23008.1.S1_S_AT similar to potassium channel tetramerisation domain containing 3; NY-REN-45 antigen gga
CHICKEN:GGAAFFX.6079.1.S1_AT similar to potassium channel tetramerisation domain containing 3; NY-REN-45 antigen gga
CHICKEN:GGAAFFX.6079.2.S1_S_AT similar to potassium channel tetramerisation domain containing 3; NY-REN-45 antigen gga
HG-U133_PLUS_2:217894_AT potassium channel tetramerisation domain containing 3 hs
HG-U133A:217894_AT potassium channel tetramerisation domain containing 3 hs
HG-FOCUS:217894_AT potassium channel tetramerisation domain containing 3 hs
HG-U133A_2:217894_AT potassium channel tetramerisation domain containing 3 hs
HU35KSUBB:RC_Z38243_AT potassium channel tetramerisation domain containing 3 hs
U133_X3P:G7705836_3P_X_AT potassium channel tetramerisation domain containing 3 hs
U133_X3P:G7705836_3P_AT potassium channel tetramerisation domain containing 3 hs
U133_X3P:217894_3P_AT potassium channel tetramerisation domain containing 3 hs
HG-U95C:57833_S_AT potassium channel tetramerisation domain containing 3 hs
HG-U95C:64451_AT potassium channel tetramerisation domain containing 3 hs
HG-U133_PLUS_2:241903_AT Potassium channel tetramerisation domain containing 3 hs
HG-U133B:241903_AT Potassium channel tetramerisation domain containing 3 hs
HG-U95B:44914_AT Potassium channel tetramerisation domain containing 3 hs
HG-U95D:73046_AT Potassium channel tetramerisation domain containing 3 hs
HU35KSUBD:RC_AA488082_AT Potassium channel tetramerisation domain containing 3 hs
U133_X3P:HS.224625.0.A1_3P_AT Potassium channel tetramerisation domain containing 3 hs
MG-U74BV2:113147_AT potassium channel tetramerisation domain containing 3 mm
MG-U74BV2:165159_R_AT potassium channel tetramerisation domain containing 3 mm
MG-U74CV2:168501_I_AT potassium channel tetramerisation domain containing 3 mm
MOE430B:1432855_AT potassium channel tetramerisation domain containing 3 mm
MOUSE430_2:1432855_AT potassium channel tetramerisation domain containing 3 mm
MOE430B:1455816_A_AT potassium channel tetramerisation domain containing 3 mm
MOUSE430_2:1455816_A_AT potassium channel tetramerisation domain containing 3 mm
MOE430B:1436811_AT potassium channel tetramerisation domain containing 3 mm
MOUSE430_2:1436811_AT potassium channel tetramerisation domain containing 3 mm
MOE430B:1459353_AT potassium channel tetramerisation domain containing 3 mm
MOUSE430_2:1459353_AT potassium channel tetramerisation domain containing 3 mm
MU19KSUBC:TC40168_AT Potassium channel tetramerisation domain containing 3, mRNA (cDNA clone MGC:90553 IMAGE:5702630) mm
RG-U34B:RC_AI071931_AT potassium channel tetramerisation domain containing 3 (predicted) rn
RAE230A:1373119_AT potassium channel tetramerisation domain containing 3 (predicted) rn
RAT230_2:1373119_AT potassium channel tetramerisation domain containing 3 (predicted) rn
RAE230B:1395941_AT potassium channel tetramerisation domain containing 3 (predicted) rn
RAT230_2:1395941_AT potassium channel tetramerisation domain containing 3 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8076 voltage-gated potassium channel complex inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5249 voltage-gated potassium channel activity inferred from electronic annotation QuickGO AmiGO
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB69932 Hypothetical protein T23B12.6 [Caenorhabditis elegans] ref|NP_505177.1| T23B12.6 [Caenorhabditis elegans] 0.0
blast CAE58389 Hypothetical protein CBG01518 [Caenorhabditis briggsae] 0.0
blast EAA05378 ENSANGP00000004083 [Anopheles gambiae str. PEST] ref|XP_309637.2| ENSANGP00000004083 [Anopheles gambiae str. PEST] 1.0E-166
Protein Domains
Database ID Description E-Value
Pfam IPR003131 EMBL-EBI K+ channel tetramerisation 1.9E-39
Sequence
Target Sequence 
>C. ELEGANS:185034_S_AT
gaatgtaacccgttttcgtggaatgattaatactcaacctggaactgtacctctggcatc
atttaaagtactcactctggattcaattgatgagacaactgataggcaatataatcatcc
gggaccttatggagatcaagattcagaacaggttcttattcaacgactgattccaaatgc
tcagaaacttttcgttagattagcttctactggagaaagaatttgcacagttgactctgt
agaggactcgccgataactgcgttctgtgtacacgagcttgatggacagaagttgggaag
tcgattaaggaaatatttattctgtggaaatggaaatggaagtgttcaagtatgggattt
aacttcagcacttgaccaatttcatcttaaaaatggatcacatccacagcaacaacaagt
gaacccacctgctgctgcaaatcaatcggaacttatcaaaccgcaattagcacagtcccc
aagatcgttaatcaatttgtcaaattattccggaggacctaccccacaagagcttctcga
cgtgattgatgacaatgacatctgctgctcgac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATGTAACCCGTTTTCGTGGAATG 276 323 1413 Antisense
TCAACCTGGAACTGTACCTCTGGCA 276 629 1446 Antisense
GGCAATATAATCATCCGGGACCTTA 692 533 1517 Antisense
GGTTCTTATTCAACGACTGATTCCA 214 507 1563 Antisense
AGAGGACTCGCCGATAACTGCGTTC 321 67 1653 Antisense
AACTGCGTTCTGTGTACACGAGCTT 672 137 1668 Antisense
ACTTCAGCACTTGACCAATTTCATC 584 103 1774 Antisense
AACAACAAGTGAACCCACCTGCTGC 393 135 1823 Antisense
TCAAACCGCAATTAGCACAGTCCCC 87 629 1868 Antisense
TAGCACAGTCCCCAAGATCGTTAAT 106 651 1880 Antisense
ATGACAATGACATCTGCTGCTCGAC 112 45 1961 Antisense
Sequence Source Affymetrix Proprietary Database