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[184978_at]

Description Y116A8A.9 /REP_DB=WormBase Gene ID /WP=CE24146 /TR=Q9U2V9 /GB=CAB55167.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 76      6grp_high1_10_10 > 66      4grp_highest_8_8 > 11      4grp_high_8_8 > 47      6grp_highest_nonorm > 84      6grp_total > 67      4grp_total > 40      6grp_highest_sub > Da      6grp_cgc > 47      6grp_high1_sub > Da      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 329
1 2 3 4 range
A 764.7
(-3)
P 		815.6
(-0.1)
P 		869.9
(3)
P 		847.4
(1.7)
P 		105
B 806.7
(-0.2)
P 		706.7
(-3)
P 		905.3
(2.6)
P 		921.1
(3)
P 		214
C 778.7
(-1.9)
P 		1035.7
(3)
P 		895
(0.3)
P 		719.8
(-3)
P 		316
avr 783.4
(-3) 		852.7
(0.9) 		890.1
(3) 		829.4
(-0.4) 		107

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 355
1 2 3 4 5 6 range
A 463.4
(-3)
P 		646.1
(1.9)
P 		561.3
(-0.4)
P 		488.6
(-2.3)
P 		545.6
(-0.8)
P 		688.5
(3)
P 		225
B 598.4
(-1)
P 		487.4
(-3)
P 		665.8
(0.2)
P 		642.1
(-0.2)
P 		508.6
(-2.6)
P 		818.6
(3)
P 		331
C 719.4
(3)
P 		503
(-2.3)
P 		576.2
(-0.5)
P 		474.2
(-3)
P 		595.9
(-0)
P 		713.9
(2.9)
P 		245
avr 593.7
(-1.3) 		545.5
(-2.7) 		601.1
(-1.1) 		535
(-3) 		550
(-2.6) 		740.3
(3) 		205
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 191
1 2 3 4 range
A 278.4
(3)
P 		177
(-0.9)
P 		227.4
(1)
P 		124
(-3)
P 		154
B 257.3
(3)
P 		174.5
(-3)
P 		209.8
(-0.4)
P 		196.3
(-1.4)
P 		83
C 257.8
(1.3)
P 		297.8
(2.6)
P 		311.9
(3)
P 		121.4
(-3)
P 		191
avr 264.5
(3) 		216.4
(0.5) 		249.7
(2.2) 		147.2
(-3) 		117

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 220
1 2 3 4 5 6 range
A 85.4
(-3)
P 		229.8
(3)
P 		122.2
(-1.5)
P 		123.9
(-1.4)
P 		164.6
(0.3)
P 		167.6
(0.4)
P 		144
B 208.2
(-1.1)
P 		162.2
(-3)
P 		161.7
(-3)
P 		170.1
(-2.6)
P 		206.6
(-1.1)
P 		305.2
(3)
P 		144
C 266.7
(3)
P 		153.5
(-1)
P 		146.7
(-1.2)
P 		95.4
(-3)
P 		192.8
(0.4)
P 		239
(2)
P 		171
avr 186.8
(0.2) 		181.8
(-0.1) 		143.5
(-2.2) 		129.8
(-3) 		188
(0.2) 		237.3
(3) 		108
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 184978_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9174
Sequence Type Exemplar sequence
Representative Public ID Y116A8A.9 NCBI
Target Description Y116A8A.9 /REP_DB=WormBase Gene ID /WP=CE24146 /TR=Q9U2V9 /GB=CAB55167.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070596(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070596 NCBI Caenorhabditis elegans Methionine AminoPeptidase family member (map-2) (map-2) mRNA, complete cds. 11/11 None
SNAP00000018653 ENSEMBL cdna:SNAP chromosome:CEL140:IV:16846076:16854880:-1 11/11 None
GENEFINDER00000018657 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:16846553:16854880:-1 11/11 None
Y116A8A.9.1 ENSEMBL cdna:known chromosome:CEL140:IV:16847788:16854880:-1 gene:Y116A8A.9 11/11 None
Y116A8A.9.2 ENSEMBL cdna:known chromosome:CEL140:IV:16847788:16854902:-1 gene:Y116A8A.9 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:16848447-16854847(-) 99.4 100.0
Public Domain and Genome References
Gene Title
Gene Symbol map-2
Ensembl Y116A8A.9
Entrez Gene 178468 Entrez gene
SwissProt Q9U2V9 EMBL-EBI
WormBase CE24146 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:20387_AT methionyl aminopeptidase, putative / methionine aminopeptidase, putative / peptidase M, putative at
ATH1-121501:267189_AT methionyl aminopeptidase, putative / methionine aminopeptidase, putative / peptidase M, putative at
CANINE:1601356_AT similar to Methionine aminopeptidase 2 (MetAP 2) (Peptidase M 2) (Initiation factor 2 associated 67 kDa glycoprotein) (p67) (p67eIF2) cfa
CANINE_2:CFA.18663.1.S1_S_AT similar to Methionine aminopeptidase 2 (MetAP 2) (Peptidase M 2) (Initiation factor 2 associated 67 kDa glycoprotein) (p67) (p67eIF2) cfa
CANINE_2:CFAAFFX.10510.1.S1_S_AT similar to Methionine aminopeptidase 2 (MetAP 2) (Peptidase M 2) (Initiation factor 2 associated 67 kDa glycoprotein) (p67) (p67eIF2) cfa
DROSOPHILA_2:1627059_AT uninitiated dm
DROSGENOME1:151903_AT uninitiated dm
CHICKEN:GGAAFFX.12872.1.S1_S_AT methionyl aminopeptidase 2 gga
CHICKEN:GGAAFFX.7229.3.S1_S_AT methionyl aminopeptidase 2 gga
HG-U133_PLUS_2:213899_AT methionyl aminopeptidase 2 hs
HG-U133A_2:213899_AT methionyl aminopeptidase 2 hs
HG-U133A:213899_AT methionyl aminopeptidase 2 hs
HG-U133_PLUS_2:209861_S_AT methionyl aminopeptidase 2 hs
HG-FOCUS:209861_S_AT methionyl aminopeptidase 2 hs
HG-U133A:209861_S_AT methionyl aminopeptidase 2 hs
HG-U133A_2:209861_S_AT methionyl aminopeptidase 2 hs
U133_X3P:G687242_3P_A_AT methionyl aminopeptidase 2 hs
U133_X3P:HS.78935.3.A1_3P_AT methionyl aminopeptidase 2 hs
HG-U133_PLUS_2:227993_AT methionyl aminopeptidase 2 hs
HG-U133B:227993_AT methionyl aminopeptidase 2 hs
HG-U95AV2:37699_AT methionyl aminopeptidase 2 hs
HG-U133A:202015_X_AT methionyl aminopeptidase 2 hs
HG-U133_PLUS_2:202015_X_AT methionyl aminopeptidase 2 hs
HG-U133A_2:202015_X_AT methionyl aminopeptidase 2 hs
HG-U133_PLUS_2:240769_AT Methionyl aminopeptidase 2 hs
HG-U133B:240769_AT Methionyl aminopeptidase 2 hs
HG-U133_PLUS_2:244185_AT Methionyl aminopeptidase 2 hs
HG-U133B:244185_AT Methionyl aminopeptidase 2 hs
HG-U95B:42989_AT Methionyl aminopeptidase 2 hs
HG-U95E:74410_AT Methionyl aminopeptidase 2 hs
HG-U95E:82674_AT Methionyl aminopeptidase 2 hs
HG-U95D:91773_AT Methionyl aminopeptidase 2 hs
HU35KSUBA:AA249336_AT Methionyl aminopeptidase 2 hs
U133_X3P:HS.129124.0.A1_3P_AT Methionyl aminopeptidase 2 hs
U133_X3P:HS.144906.0.A1_3P_AT Methionyl aminopeptidase 2 hs
MU11KSUBA:AB003144_S_AT methionine aminopeptidase 2 mm
MU11KSUBB:MSA.21376.0_S_AT methionine aminopeptidase 2 mm
MG-U74AV2:93505_AT methionine aminopeptidase 2 mm
MOE430A:1423610_AT methionine aminopeptidase 2 mm
MOUSE430A_2:1423610_AT methionine aminopeptidase 2 mm
MOUSE430_2:1423610_AT methionine aminopeptidase 2 mm
MOE430A:1451048_AT methionine aminopeptidase 2 mm
MOUSE430A_2:1451048_AT methionine aminopeptidase 2 mm
MOUSE430_2:1451048_AT methionine aminopeptidase 2 mm
MOE430A:1434120_A_AT methionine aminopeptidase 2 mm
MOUSE430A_2:1434120_A_AT methionine aminopeptidase 2 mm
MOUSE430_2:1434120_A_AT methionine aminopeptidase 2 mm
MOE430B:1436531_AT methionine aminopeptidase 2 mm
MOUSE430_2:1436531_AT methionine aminopeptidase 2 mm
MU19KSUBC:TC38627_S_AT Methionine aminopeptidase 2, mRNA (cDNA clone MGC:102452 IMAGE:3670685) mm
MU19KSUBC:TC40545_AT Methionine aminopeptidase 2 (Metap2) mm
RG-U34A:L10652_G_AT methionine aminopeptidase 2 rn
RG-U34A:L10652_AT methionine aminopeptidase 2 rn
RAE230A:1398798_AT methionine aminopeptidase 2 rn
RAT230_2:1398798_AT methionine aminopeptidase 2 rn
YEAST_2:1777028_AT Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4239 methionyl aminopeptidase activity inferred from electronic annotation QuickGO AmiGO
8235 metalloexopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB55167 Hypothetical protein Y116A8A.9 [Caenorhabditis elegans] ref|NP_502997.1| Methionine AminoPeptidase family member (map-2) [Caenorhabditis elegans] 0.0
blast CAE68064 Hypothetical protein CBG13686 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000994 EMBL-EBI Peptidase M24 1.4E-15
Pfam IPR000994 EMBL-EBI Peptidase M24 1.4E-15
Sequence
Target Sequence 
>C. ELEGANS:184978_AT
tagtcgaagcagtccgtgaagccaccaatgccggaatcaaagaatccggaatcgacgttc
gcctctgtgatgtcggagaaattgtcgaagaagtgatgacgtcacacgaggtggaactcg
acggaaagtcgtatgtggtgaagccgattcgcaatctcaacggacactcgatcgcccaat
accgtattcacgccggcaagaccgtaccaattgtgaagggtggtgaacagacaaaaatgg
aggagaacgagatctacgcaattgagacattcggatctacgggaaaaggatatgttcatg
atgatatggaaacgtcgcattatatgaagaatttcgagctcgccgacgagaaaattccac
ttcgcttgcaaaaatcgaagggattgctcaacttgatcgataagaatttcgccacactgg
ctttctgtcgtcgttggattgatcgtcttggagagaccaagtacttgatggctctcaagg
atttgtgtgataagggaatcgtcgatccatatccaccactctgtgacgtcaaaggatgct
acactgctcaatgggagcacacaattctgatgcgtccg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TAGTCGAAGCAGTCCGTGAAGCCAC 97 653 731 Antisense
GAAGCCACCAATGCCGGAATCAAAG 558 343 748 Antisense
CGTTCGCCTCTGTGATGTCGGAGAA 450 247 786 Antisense
GGTGAAGCCGATTCGCAATCTCAAC 462 499 867 Antisense
TCGATCGCCCAATACCGTATTCACG 604 599 898 Antisense
CGTATTCACGCCGGCAAGACCGTAC 266 245 913 Antisense
TGGCTTTCTGTCGTCGTTGGATTGA 280 545 1148 Antisense
AGGGAATCGTCGATCCATATCCACC 426 57 1223 Antisense
TATCCACCACTCTGTGACGTCAAAG 419 657 1240 Antisense
AAGGATGCTACACTGCTCAATGGGA 79 159 1262 Antisense
GGAGCACACAATTCTGATGCGTCCG 25 521 1284 Antisense
Sequence Source Affymetrix Proprietary Database