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[184686_at] 7TM chemoreceptor, sre family

Description C50E10.9 /REP_DB=WormBase Gene ID /WP=CE19763 /TR=Q9TZJ4 /GB=AAC67433.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_total > 36      4grp_total > 28      6grp_cgc > 25      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 49
1 2 3 4 range
A 46.4
(3)
A 		12.2
(-2.4)
A 		8.3
(-3)
A 		20.7
(-1)
A 		38
B 8.2
(-2.8)
A 		50.6
(3)
A 		6.5
(-3)
A 		46.4
(2.4)
A 		44
C 10.3
(-2.3)
A 		34.7
(0.7)
A 		4.8
(-3)
A 		53.3
(3)
A 		49
avr 21.6
(-0.3) 		32.5
(1.6) 		6.5
(-3) 		40.1
(3) 		34

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 37
1 2 3 4 5 6 range
A 18.4
(-0.1)
A 		23.1
(0.8)
A 		21
(0.4)
A 		34.2
(3)
A 		9
(-1.9)
A 		3.4
(-3)
A 		31
B 15.4
(-0.9)
A 		13.8
(-1.1)
A 		12.6
(-1.3)
A 		3.1
(-2.9)
A 		2.2
(-3)
A 		39.2
(3)
A 		37
C 32.9
(3)
A 		32.2
(2.9)
A 		4.9
(-3)
A 		6.3
(-2.7)
A 		10.3
(-1.8)
A 		17.9
(-0.2)
A 		28
avr 22.2
(2.7) 		23
(3) 		12.8
(-0.9) 		14.5
(-0.2) 		7.2
(-3) 		20.2
(1.9) 		16
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 15
1 2 3 4 range
A 16.9
(3)
A 		2.6
(-2.8)
A 		2.2
(-3)
A 		3
(-2.7)
A 		15
B 2.6
(-2.4)
A 		12.5
(3)
A 		1.5
(-3)
A 		9.9
(1.6)
A 		11
C 3.4
(-1.8)
A 		10
(3)
A 		1.7
(-3)
A 		9
(2.3)
A 		8
avr 7.6
(2.3) 		8.4
(3) 		1.8
(-3) 		7.3
(2) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 14
1 2 3 4 5 6 range
A 3.4
(-1)
A 		8.2
(2.6)
A 		4.6
(-0.1)
A 		8.7
(3)
A 		2.7
(-1.6)
A 		0.8
(-3)
A 		8
B 5.3
(-1)
A 		4.6
(-1.3)
A 		3
(-2)
A 		0.8
(-3)
A 		0.9
(-3)
A 		14.6
(3)
A 		14
C 12.2
(3)
A 		9.8
(1.7)
A 		1.3
(-3)
A 		1.3
(-3)
A 		3.3
(-1.9)
A 		6
(-0.4)
A 		11
avr 7
(2.4) 		7.5
(3) 		3
(-2.2) 		3.6
(-1.5) 		2.3
(-3) 		7.1
(2.5) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 184686_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3928
Sequence Type Exemplar sequence
Representative Public ID C50E10.9 NCBI
Target Description C50E10.9 /REP_DB=WormBase Gene ID /WP=CE19763 /TR=Q9TZJ4 /GB=AAC67433.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064214(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064214 NCBI Caenorhabditis elegans Serpentine Receptor, class E (epsilon) family member (sre-49) (sre-49) mRNA, complete cds. 10/11 None
GENEFINDER00000034847 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12311763:12320973:1 11/11 None
C50E10.9 ENSEMBL cdna:known chromosome:CEL140:II:12318744:12320973:1 gene:C50E10.9 10/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12318075-12320970(+) 96.98 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, sre family
Gene Symbol sre-49
Ensembl C50E10.9
Entrez Gene 183670 Entrez gene
SwissProt Q965H9 EMBL-EBI
WormBase CE38060 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7606 sensory perception of chemical stimulus inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_496615 Serpentine Receptor, class E (epsilon) family member (sre-49) [Caenorhabditis elegans] gb|AAK73868.3| Serpentine receptor, class e (epsilon) protein 49 [Caenorhabditis elegans] 0.0
blast NP_496614 Serpentine Receptor, class E (epsilon) family member (sre-51) [Caenorhabditis elegans] gb|AAK73859.5| Serpentine receptor, class e (epsilon) protein 51 [Caenorhabditis elegans] 0.0
blast T33505 hypothetical protein C50E10.10 - Caenorhabditis elegans 0.0
blast CAE73490 Hypothetical protein CBG20945 [Caenorhabditis briggsae] 1.0E-132
blast CAE57079 Hypothetical protein CBG24976 [Caenorhabditis briggsae] 1.0E-122
blast CAA21692 Hypothetical protein Y57A10B.5 [Caenorhabditis elegans] ref|NP_496628.1| Serpentine Receptor, class E (epsilon) family member (sre-41) [Caenorhabditis elegans] 2.0E-37
Protein Domains
Database ID Description E-Value
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 2.7E-56
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 3.6E-78
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 7.7E-29
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496615.2 7 28-50,63-85,123-145,166-188,193-215,253-275,285-307
C50E10.9 7 28-50,63-85,123-145,166-188,193-215,253-275,285-307
GENEFINDER00000034847 13 27-46,58-77,122-144,165-187,192-214,252-274,289-308,380-402,417-435,493-515,520-542,580-602,612-634
Sequence
Target Sequence 
>C. ELEGANS:184686_AT
caaacttccccaattttcagtgactacgaacgtaaaactcgtccttacatttcaattgcc
ataataattgtttcaatgctattttcatctgcctattctgtattttttgcattcaatttt
ttcaacctgacttttattgtaatcgtactggttacggtagcctcaactacactatacaca
tcggttttctactacaacactcgaattaagaaaatttcggacaaaaattcgaaacgcgaa
aattatacgttggcgagaagatttcaaacgatggagaacttgaaatcgttgaggatggca
aaatacgtggtttcaacgcacgcggtttacgtgtccctctgcgaagtgtgcttcatctgt
gtatattatggagctgaatcaaattattgggaagtttttggatatattttggattttgtg
gtttcttacagcaactgtataatcgttctcatcgtgattttctcagtaccatgctggaaa
aagtcgtttctccgtcctttatacatgtttcgaaggatgcaatcaaatcgggtatctatg
gcatcacaggaaaaggatcccgaggaggacgcccggcaaatttct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CAAACTTCCCCAATTTTCAGTGACT 223 189 844 Antisense
AACTCGTCCTTACATTTCAATTGCC 244 141 879 Antisense
TATTTTCATCTGCCTATTCTGTATT 385 663 923 Antisense
CGTACTGGTTACGGTAGCCTCAACT 313 245 987 Antisense
AGCCTCAACTACACTATACACATCG 57 85 1002 Antisense
ATCGGTTTTCTACTACAACACTCGA 368 35 1023 Antisense
GTGGTTTCAACGCACGCGGTTTACG 309 485 1150 Antisense
GAAGTGTGCTTCATCTGTGTATATT 658 335 1186 Antisense
ATCGTTCTCATCGTGATTTTCTCAG 591 35 1285 Antisense
TTCTCCGTCCTTTATACATGTTTCG 471 693 1331 Antisense
CGAGGAGGACGCCCGGCAAATTTCT 547 197 1404 Antisense
Sequence Source Affymetrix Proprietary Database