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[184608_s_at] importin beta, nuclear transport factor

Description C49H3.10 /REP_DB=WormBase Gene ID /WP=CE27871 /TR=Q9GYQ7 /GB=AAF99897.2 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 93      6grp_high1_10_10 > 49      4grp_highest_8_8 > 41      4grp_high_8_8 > 50      6grp_highest_nonorm > 82      6grp_total > 38      4grp_total > 53      6grp_highest_sub > Cu      6grp_cgc > 08      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 213
1 2 3 4 range
A 455.5
(3)
P 		323.5
(-1.7)
P 		331.4
(-1.4)
P 		287.1
(-3)
P 		168
B 364.5
(2.4)
P 		377.6
(3)
P 		350.1
(1.8)
P 		242.6
(-3)
P 		135
C 408.2
(3)
P 		397.6
(2.4)
P 		395.2
(2.2)
P 		305.4
(-3)
P 		103
avr 409.4
(3) 		366.2
(1) 		358.9
(0.7) 		278.4
(-3) 		131

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 212
1 2 3 4 5 6 range
A 347.7
(1.5)
P 		301.6
(-1.2)
P 		270.5
(-3)
P 		275.3
(-2.7)
P 		373.7
(3)
P 		366.8
(2.6)
P 		103
B 482.3
(3)
P 		401.1
(0.6)
P 		282.3
(-3)
P 		465.5
(2.5)
P 		318.1
(-1.9)
P 		373.8
(-0.3)
P 		200
C 411.3
(3)
P 		328.8
(-1)
P 		287.3
(-3)
P 		317
(-1.6)
P 		321.3
(-1.4)
P 		380
(1.5)
P 		124
avr 413.8
(3) 		343.8
(-0.1) 		280
(-3) 		352.6
(0.3) 		337.7
(-0.4) 		373.5
(1.2) 		134
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 124
1 2 3 4 range
A 165.9
(3)
P 		70.2
(-1.6)
P 		86.6
(-0.8)
P 		42
(-3)
P 		124
B 116.2
(3)
P 		93.2
(0.9)
P 		81.1
(-0.3)
P 		51.7
(-3)
P 		65
C 135.1
(2.8)
P 		114.3
(1.4)
P 		137.7
(3)
P 		51.5
(-3)
P 		86
avr 139.1
(3) 		92.6
(-0.1) 		101.8
(0.5) 		48.4
(-3) 		91

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 109
1 2 3 4 5 6 range
A 64.1
(-2.4)
P 		107.3
(2.4)
P 		58.9
(-3)
P 		69.8
(-1.8)
P 		112.8
(3)
P 		89.3
(0.4)
P 		54
B 167.8
(3)
P 		133.5
(0.9)
P 		68.6
(-3)
P 		123.3
(0.3)
P 		129.2
(0.7)
P 		139.4
(1.3)
P 		99
C 152.5
(3)
P 		100.3
(-0.5)
P 		73.1
(-2.4)
P 		63.7
(-3)
P 		104
(-0.3)
P 		127.2
(1.3)
P 		89
avr 128.1
(3) 		113.7
(1.6) 		66.9
(-3) 		85.6
(-1.2) 		115.3
(1.7) 		118.6
(2.1) 		61
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 184608_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10318
Sequence Type Exemplar sequence
Representative Public ID C49H3.10 NCBI
Target Description C49H3.10 /REP_DB=WormBase Gene ID /WP=CE27871 /TR=Q9GYQ7 /GB=AAF99897.2 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068919(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068919 NCBI Caenorhabditis elegans IMportin Beta family member (imb-6) (imb-6) mRNA, complete cds. 9/11 None
C49H3.10 ENSEMBL cdna:known chromosome:CEL140:IV:7916355:7924110:-1 gene:C49H3.10 9/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000028670 4/11 Cross Hyb Matching Probes None
GENEFINDER00000028678 4/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:7916845-7924021(-) 97.02 100.0
Public Domain and Genome References
Gene Title importin beta, nuclear transport factor
Gene Symbol imb-6
Ensembl C49H3.10
Entrez Gene 177581 Entrez gene
SwissProt Q9GYQ7 EMBL-EBI
WormBase CE29726 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:259919_AT tRNA export mediator exportin-t, putative (PAUSED) at
CANINE_2:CFAAFFX.1483.1.S1_AT similar to Exportin-T (tRNA exportin) (Exportin(tRNA)) cfa
CHICKEN:GGAAFFX.6166.1.S1_AT similar to tRNA exportin; EXPORTIN-T gga
HU35KSUBA:AA094023_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HU35KSUBA:R19997_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HU35KSUBC:RC_AA598447_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HU35KSUBD:RC_H99877_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
U133_X3P:HS.85951.0.S2_3P_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-U133A_2:212160_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-FOCUS:212160_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-U133_PLUS_2:212160_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-U133A:212160_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-U95AV2:38753_AT exportin, tRNA (nuclear export receptor for tRNAs) hs
HU35KSUBA:RC_AA282481_AT Exportin, tRNA (nuclear export receptor for tRNAs) hs
U133_X3P:HS.18439.0.A1_3P_AT Exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-U133_PLUS_2:227117_AT Exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-U133B:227117_AT Exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-U95C:60502_AT Exportin, tRNA (nuclear export receptor for tRNAs) hs
HG-U95D:86857_R_AT Exportin, tRNA (nuclear export receptor for tRNAs) hs
MU11KSUBA:C79645_RC_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MG-U74AV2:94340_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MG-U74AV2:161797_R_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MG-U74BV2:162910_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOE430A:1428772_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOUSE430A_2:1428772_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOUSE430_2:1428772_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOE430B:1428949_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOUSE430_2:1428949_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOE430B:1441681_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOUSE430_2:1441681_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOE430B:1441682_S_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
MOUSE430_2:1441682_S_AT exportin, tRNA (nuclear export receptor for tRNAs) mm
RAE230B:1393983_AT exportin, tRNA (nuclear export receptor for tRNAs) (predicted) rn
RAT230_2:1393983_AT exportin, tRNA (nuclear export receptor for tRNAs) (predicted) rn
RAE230A:1371818_AT Exportin, tRNA (nuclear export receptor for tRNAs) (predicted) rn
RAT230_2:1371818_AT Exportin, tRNA (nuclear export receptor for tRNAs) (predicted) rn
RG-U34C:RC_AI233182_AT Exportin, tRNA (nuclear export receptor for tRNAs) (predicted) rn
YEAST_2:1771901_AT Nuclear pore protein involved in nuclear export of pre-tRNA Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6409 tRNA export from nucleus inferred from electronic annotation QuickGO AmiGO
6409 tRNA export from nucleus inferred from sequence similarity QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
5737 cytoplasm inferred from electronic annotation QuickGO AmiGO
5634 nucleus inferred from sequence similarity QuickGO AmiGO
5737 cytoplasm inferred from sequence similarity QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
49 tRNA binding inferred from electronic annotation QuickGO AmiGO
49 tRNA binding inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF99897 Importin beta family protein 6 [Caenorhabditis elegans] ref|NP_501320.2| IMportin Beta family member (imb-6) [Caenorhabditis elegans] 0.0
blast CAE70909 Hypothetical protein CBG17706 [Caenorhabditis briggsae] 0.0
blast T34182 hypothetical protein C49H3.10 - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR007279 EMBL-EBI Exportin-t 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:184608_S_AT
accagtctacatcaatctgatccggatggatttacacgagcactcagagagcttgttccc
aatggattctcagatcaactactgtcagcattaaccaatttgaaaggaaagaatctagat
aaacaggttaaactttcgttcgatttcaaaaagataattgatttttccccaaatgcgtca
tcggaaattttttggattaaaaaaaaagaaaaaactcgaaataaaaacgaaaattttcga
ttctttggaaaatcgagaaaaaatgtttataaaattaaccataaaatttttttaaatcaa
attttgtttctggccatgaccatgaaacataattttcttctaaaaataaaaaaaactgac
caaaattttaagctcttttcgaaaaatgaattggatcaagttgttgttaatcttattccc
cttacccgtattctgatggttttttgtttgttcgctgttcaactttttccttcacaattc
ctaagtgccctttttgaaaattctattgaaatttgcagacttgacgttattcgggtgttt
ttctctttctatactcaacaaattatgttccttccttttaacatcatcatca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACCAGTCTACATCAATCTGATCCGG 244 87 2917 Antisense
TCCGGATGGATTTACACGAGCACTC 210 595 2937 Antisense
GAGCACTCAGAGAGCTTGTTCCCAA 647 389 2954 Antisense
GTTCCCAATGGATTCTCAGATCAAC 575 441 2971 Antisense
ATTGATTTTTCCCCAAATGCGTCAT 431 5 3073 Antisense
ATTTTGTTTCTGGCCATGACCATGA 32 15 3217 Antisense
TTTGTTCGCTGTTCAACTTTTTCCT 542 667 3363 Antisense
CACAATTCCTAAGTGCCCTTTTTGA 40 193 3389 Antisense
GCAGACTTGACGTTATTCGGGTGTT 4 313 3431 Antisense
GTGTTTTTCTCTTTCTATACTCAAC 79 487 3451 Antisense
TTCCTTCCTTTTAACATCATCATCA 531 699 3484 Antisense
Sequence Source Affymetrix Proprietary Database