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[184596_s_at]

Description F57H12.7 /REP_DB=WormBase Gene ID /WP=CE17128 /TR=O45100 /GB=AAC02603.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 21      6grp_high1_10_10 > 13      4grp_highest_8_8 > 48      4grp_high_8_8 > 42      6grp_highest_nonorm > 21      6grp_total > 14      4grp_total > 53      6grp_highest_sub > De      6grp_cgc > 30      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1616
1 2 3 4 range
A 2154.9
(3)
P 		1589.3
(0.9)
P 		1077.5
(-1)
P 		539
(-3)
P 		1616
B 1870.1
(3)
P 		1393.7
(0.5)
P 		925.5
(-2)
P 		739.4
(-3)
P 		1131
C 1819.1
(3)
P 		1515
(1.5)
P 		1124.6
(-0.5)
P 		611.9
(-3)
P 		1207
avr 1948
(3) 		1499.3
(1) 		1042.5
(-1.1) 		630.1
(-3) 		1318

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1208
1 2 3 4 5 6 range
A 1664.5
(3)
P 		1497.6
(2)
P 		1268.6
(0.6)
P 		1284.6
(0.7)
P 		670.7
(-3)
P 		676.3
(-3)
P 		994
B 1748.6
(3)
P 		1699.3
(2.8)
P 		1071.7
(-0.4)
P 		891
(-1.3)
P 		753.3
(-1.9)
P 		540.8
(-3)
P 		1208
C 1726.4
(3)
P 		1547.5
(2.1)
P 		1130.6
(-0.1)
P 		1269.1
(0.6)
P 		659.3
(-2.6)
P 		580.8
(-3)
P 		1146
avr 1713.2
(3) 		1581.5
(2.3) 		1157
(0) 		1148.2
(-0) 		694.4
(-2.5) 		599.3
(-3) 		1114
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 706
1 2 3 4 range
A 784.6
(3)
P 		345
(-0.7)
P 		281.7
(-1.3)
P 		78.9
(-3)
P 		706
B 596.4
(3)
P 		344.2
(-0.4)
P 		214.5
(-2.2)
P 		157.6
(-3)
P 		439
C 602.2
(3)
P 		435.6
(1)
P 		392
(0.5)
P 		103.2
(-3)
P 		499
avr 661.1
(3) 		374.9
(-0.1) 		296.1
(-1) 		113.2
(-3) 		548

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 475
1 2 3 4 5 6 range
A 306.8
(-0.7)
P 		532.6
(3)
P 		276.3
(-1.2)
P 		325.8
(-0.4)
P 		202.4
(-2.4)
P 		164.6
(-3)
P 		368
B 608.4
(3)
P 		565.6
(2.4)
P 		260.2
(-2.1)
P 		236
(-2.5)
P 		306
(-1.5)
P 		201.7
(-3)
P 		407
C 639.9
(3)
P 		472.2
(0.7)
P 		287.8
(-1.7)
P 		255.2
(-2.2)
P 		213.4
(-2.7)
P 		194.4
(-3)
P 		446
avr 518.4
(2.9) 		523.5
(3) 		274.8
(-1.4) 		272.3
(-1.5) 		240.6
(-2) 		186.9
(-3) 		337
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 184596_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8373
Sequence Type Exemplar sequence
Representative Public ID F57H12.7 NCBI
Target Description F57H12.7 /REP_DB=WormBase Gene ID /WP=CE17128 /TR=O45100 /GB=AAC02603.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068936(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068936 NCBI Caenorhabditis elegans MEChanosensory abnormality family member (mec-17) (mec-17) mRNA, complete cds. 11/11 None
SNAP00000044157 ENSEMBL cdna:SNAP chromosome:CEL140:IV:7983997:7985684:-1 11/11 None
GENEFINDER00000044158 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:7983997:7987135:-1 11/11 None
F57H12.7 ENSEMBL cdna:known chromosome:CEL140:IV:7983845:7987166:-1 gene:F57H12.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:7984002-7987141(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol mec-17
Ensembl F57H12.7
Entrez Gene 177596 Entrez gene
SwissProt O45100 EMBL-EBI
WormBase CE17128 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1624429_AT dm
DROSOPHILA_2:1630582_S_AT dm
DROSGENOME1:153386_AT dm
Protein Similarities
Method ID Description E-Value
blast AAC02603 Mechanosensory abnormality protein 17 [Caenorhabditis elegans] ref|NP_501337.1| MEChanosensory abnormality family member (mec-17) [Caenorhabditis elegans] 1.0E-151
blast CAE70926 Hypothetical protein CBG17726 [Caenorhabditis briggsae] 1.0E-142
blast AAC02603 Mechanosensory abnormality protein 17 [Caenorhabditis elegans] ref|NP_501337.1| MEChanosensory abnormality family member (mec-17) [Caenorhabditis elegans] 1.0E-136
blast CAE70926 Hypothetical protein CBG17726 [Caenorhabditis briggsae] 1.0E-127
blast EAA11927 ENSANGP00000017438 [Anopheles gambiae str. PEST] ref|XP_315853.2| ENSANGP00000017438 [Anopheles gambiae str. PEST] 6.0E-27
blast EAA11927 ENSANGP00000017438 [Anopheles gambiae str. PEST] ref|XP_315853.2| ENSANGP00000017438 [Anopheles gambiae str. PEST] 7.0E-27
Protein Domains
Database ID Description E-Value
Pfam IPR007965 EMBL-EBI Protein of unknown function DUF738 1.6E-82
Pfam IPR007965 EMBL-EBI Protein of unknown function DUF738 1.6E-82
Sequence
Target Sequence 
>C. ELEGANS:184596_S_AT
gaagcttatcaactccgattcaactttatatctctcttggaaatatgatgaagaagagaa
ggttagtcgactcatgggattcgcgaaagtaggaagaaagaagttattcctttatgactc
tcaaatgcagacttatgagggagagattctgtgtcttctggacttttatgttcacttctc
atgtcaacgccaaggagttggacaacaaattctagattacatgttctctcaggaacacac
tgaaccttatcaattggctcttgataatccatcagtcactcttcttggttttatgtcaca
aaagtacggacttatcaagcctgtatggcagaataccaatttcgttgttttcgaggagct
cttcctagctttgtcggctgaaaatggaatcgaaaaacctccaccagatggttggcgtcg
tccaatgactccacgtcgattgggaactggaatgactgatacccgttggcttcaacacgc
tgttagtggtcatcagagcaagggaaatgcaatggctgctccggtggatgctgacatgac
accacaaggtgctttgagcaatagagctcatcaggccaaggcaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAGCTTATCAACTCCGATTCAACT 150 343 180 Antisense
GGAGAGATTCTGTGTCTTCTGGACT 322 519 319 Antisense
TCTGGACTTTTATGTTCACTTCTCA 265 605 336 Antisense
TCACTTCTCATGTCAACGCCAAGGA 102 627 351 Antisense
TGATAATCCATCAGTCACTCTTCTT 168 565 441 Antisense
GTCACTCTTCTTGGTTTTATGTCAC 568 465 454 Antisense
CTCTTCCTAGCTTTGTCGGCTGAAA 292 229 538 Antisense
GATGGTTGGCGTCGTCCAATGACTC 455 405 586 Antisense
TGGAATGACTGATACCCGTTGGCTT 611 543 627 Antisense
GGATGCTGACATGACACCACAAGGT 682 511 705 Antisense
AATAGAGCTCATCAGGCCAAGGCAA 114 173 739 Antisense
Sequence Source Affymetrix Proprietary Database