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[184595_s_at]

Description C26E6.11 /REP_DB=WormBase Gene ID /WP=CE01159 /TR=Q18218 /GB=AAA21165.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 36      6grp_high1_10_10 > 62      4grp_highest_8_8 > 18      4grp_high_8_8 > 62      6grp_highest_nonorm > 54      6grp_total > 62      4grp_total > 59      6grp_highest_sub > 03      6grp_cgc > 75      6grp_high1_sub > 03      6grp_cgc_sub > 03_04      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 955
1 2 3 4 range
A 854.1
(-0.1)
P 		944.8
(0.5)
P 		1340.9
(3)
P 		386.1
(-3)
P 		955
B 808.5
(-0.8)
P 		1086
(1.5)
P 		1266.5
(3)
P 		545.6
(-3)
P 		721
C 869.6
(-0.1)
P 		1048.5
(1.3)
P 		1268.5
(3)
P 		492.9
(-3)
P 		776
avr 844.1
(-0.3) 		1026.4
(1) 		1292
(3) 		474.9
(-3) 		817

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1020
1 2 3 4 5 6 range
A 814.6
(-3)
P 		1247.6
(-0.1)
P 		1354
(0.6)
P 		1713.2
(3)
P 		1117.7
(-1)
P 		1138.2
(-0.8)
P 		899
B 819.6
(-3)
P 		1220.9
(0.1)
P 		1589.7
(3)
P 		1218.7
(0.1)
P 		1146.3
(-0.5)
P 		981.5
(-1.7)
P 		770
C 973.9
(-3)
P 		969.2
(-3)
P 		1834.2
(3)
P 		1217.8
(-1.3)
P 		1220.2
(-1.3)
P 		1087.2
(-2.2)
P 		865
avr 869.4
(-3) 		1145.9
(-0.7) 		1592.6
(3) 		1383.2
(1.3) 		1161.4
(-0.6) 		1069
(-1.3) 		723
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 386
1 2 3 4 range
A 311
(2.2)
P 		205.1
(0)
P 		350.5
(3)
P 		56.5
(-3)
P 		294
B 257.8
(1.8)
P 		268.2
(2.1)
P 		293.5
(3)
P 		116.3
(-3)
P 		177
C 287.9
(0.4)
P 		301.5
(0.7)
P 		442.1
(3)
P 		83.1
(-3)
P 		359
avr 285.6
(1.3) 		258.3
(0.8) 		362
(3) 		85.3
(-3) 		277

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 317
1 2 3 4 5 6 range
A 150.2
(-3)
P 		443.7
(3)
P 		294.9
(-0)
P 		434.5
(2.8)
P 		337.3
(0.8)
P 		277.1
(-0.4)
P 		294
B 285.2
(-3)
P 		406.4
(1)
P 		386
(0.4)
P 		322.8
(-1.8)
P 		465.7
(3)
P 		366
(-0.3)
P 		181
C 361
(0.1)
P 		295.7
(-1.6)
P 		466.8
(3)
P 		244.9
(-3)
P 		394.8
(1.1)
P 		364
(0.2)
P 		222
avr 265.5
(-3) 		381.9
(2.2) 		382.6
(2.3) 		334.1
(0.1) 		399.3
(3) 		335.7
(0.1) 		134
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 184595_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7708
Sequence Type Exemplar sequence
Representative Public ID C26E6.11 NCBI
Target Description C26E6.11 /REP_DB=WormBase Gene ID /WP=CE01159 /TR=Q18218 /GB=AAA21165.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065637(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065637 NCBI Caenorhabditis elegans C26E6.11 (C26E6.11) mRNA, complete cds. 11/11 None
GENEFINDER00000014714 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4918092:4930092:-1 11/11 None
SNAP00000014696 ENSEMBL cdna:SNAP chromosome:CEL140:III:4920509:4921708:-1 11/11 None
C26E6.11 ENSEMBL cdna:known chromosome:CEL140:III:4920394:4922292:-1 gene:C26E6.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4920508-4922292(-) 99.12 100.0
Public Domain and Genome References
Gene Title
Gene Symbol tag-339
Ensembl C26E6.11
Entrez Gene 175661 Entrez gene
SwissProt Q18218 EMBL-EBI
WormBase CE01159 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.16832.1.S1_AT similar to cob(I)alamin adenosyltransferase cfa
CANINE_2:CFA.16832.1.S1_S_AT similar to cob(I)alamin adenosyltransferase cfa
CANINE_2:CFAAFFX.16958.1.S1_AT similar to cob(I)alamin adenosyltransferase cfa
CHICKEN:GGA.2847.2.S1_A_AT similar to methylmalonic aciduria (cobalamin deficiency) type B homolog; ATP:Cob(I)alamin Adenosyltransferase gga
HU35KSUBA:RC_AA400259_AT methylmalonic aciduria (cobalamin deficiency) cblB type hs
U133_X3P:HS.271865.0.A1_3P_AT methylmalonic aciduria (cobalamin deficiency) cblB type hs
U133_X3P:HS.12106.0.S1_3P_AT methylmalonic aciduria (cobalamin deficiency) cblB type hs
HG-U133_PLUS_2:225826_AT methylmalonic aciduria (cobalamin deficiency) cblB type hs
HG-U133B:225826_AT methylmalonic aciduria (cobalamin deficiency) cblB type hs
HG-U133_PLUS_2:242082_AT methylmalonic aciduria (cobalamin deficiency) cblB type hs
HG-U133B:242082_AT methylmalonic aciduria (cobalamin deficiency) cblB type hs
HG-U95B:57556_AT methylmalonic aciduria (cobalamin deficiency) cblB type hs
MG-U74BV2:109473_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOE430A:1452468_S_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOUSE430A_2:1452468_S_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOUSE430_2:1452468_S_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOE430A:1452467_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOUSE430A_2:1452467_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOUSE430_2:1452467_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOE430A:1435097_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOUSE430A_2:1435097_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOUSE430_2:1435097_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOE430B:1443498_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MOUSE430_2:1443498_AT methylmalonic aciduria (cobalamin deficiency) type B homolog (human) mm
MU19KSUBA:TC14561_AT Methylmalonic aciduria (cobalamin deficiency) type B homolog (human) (Mmab), mRNA mm
MU19KSUBA:TC14561_G_AT Methylmalonic aciduria (cobalamin deficiency) type B homolog (human) (Mmab), mRNA mm
Protein Similarities
Method ID Description E-Value
blast AAA21165 Hypothetical protein C26E6.11 [Caenorhabditis elegans] ref|NP_498038.1| C26E6.11 [Caenorhabditis elegans] 0.0
blast AAK67214 Set (trithorax/polycomb) domain containing protein 2, isoform a [Caenorhabditis elegans] ref|NP_498040.1| SET (trithorax/polycomb) domain containing family member (set-2) [Caenorhabditis elegans] sp|Q18221|SET2_CAEEL Protein set-2 0.0
blast AAK67215 Set (trithorax/polycomb) domain containing protein 2, isoform c [Caenorhabditis elegans] ref|NP_498039.1| SET (trithorax/polycomb) domain containing family member (set-2) [Caenorhabditis elegans] 0.0
blast H88444 protein C26E6.12 [imported] - Caenorhabditis elegans 0.0
blast AAA21165 Hypothetical protein C26E6.11 [Caenorhabditis elegans] ref|NP_498038.1| C26E6.11 [Caenorhabditis elegans] 1.0E-137
blast CAE71302 Hypothetical protein CBG18191 [Caenorhabditis briggsae] 1.0E-111
blast NP_084232 methylmalonic aciduria (cobalamin deficiency) type B homolog [Mus musculus] gb|AAH57558.1| Methylmalonic aciduria (cobalamin deficiency) type B homolog [Mus musculus] dbj|BAE28544.1| unnamed protein product [Mus musculus] dbj|BAB32055.1| unnamed protein product [Mus musculus] dbj|BAC40571.1| unnamed protein product [Mus musculus] sp|Q9D273|MMAB_MOUSE Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial precursor (Cob(I)alamin adenosyltransferase) (Methylmalonic aciduria type B homolog) 3.0E-35
Protein Domains
Database ID Description E-Value
Pfam IPR000594 EMBL-EBI UBA/THIF-type NAD/FAD binding fold 3.1E-37
Pfam IPR000504 EMBL-EBI RNA-binding region RNP-1 (RNA recognition motif) 2.4E-8
Pfam IPR001214 EMBL-EBI Nuclear protein SET 1.6E-54
Pfam IPR002779 EMBL-EBI Protein of unknown function DUF80 3.8E-80
Pfam IPR002779 EMBL-EBI Protein of unknown function DUF80 4.6E-80
Pfam IPR002779 EMBL-EBI Protein of unknown function DUF80 4.6E-80
Sequence
Target Sequence 
>C. ELEGANS:184595_S_AT
gggcaatcttctctgtacaacaatgagcgtcgctggaaagatgacgacactttcaatgct
ctcggagcaaccgatgaattgtcttcatttcttggtgtctgtggagcatctgctcaaaac
gatggttcaatgagcgatgtagtggagacattaacacgccttcaatgttgtctacaggat
gttggagctcatcttgctactccaccaaaaaattcttcggagagaaaacaaaagaaaact
gcattcgatattgcaatggttgaatggataaatgcagaaatcgatcgatacggagacgcg
ttgcctgcaatccgacaatttattctttctggcggtggaatgacgtctgctcaattacag
tattcccgcgcaatttgtcgtcgagctgaacggagtattgttccacttatgagagacgaa
gacgtcgatccaatggcattaaagttcttgaatagaatgagcgatcttctatttgttctc
ggtcgtactgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGGCAATCTTCTCTGTACAACAATG 52 491 445 Antisense
GACGACACTTTCAATGCTCTCGGAG 493 379 487 Antisense
ATTGTCTTCATTTCTTGGTGTCTGT 305 5 522 Antisense
TTGGTGTCTGTGGAGCATCTGCTCA 380 709 536 Antisense
AACACGCCTTCAATGTTGTCTACAG 581 135 597 Antisense
GTTGGAGCTCATCTTGCTACTCCAC 532 435 625 Antisense
GATCGATACGGAGACGCGTTGCCTG 325 417 727 Antisense
CGTTGCCTGCAATCCGACAATTTAT 592 247 743 Antisense
CTGCTCAATTACAGTATTCCCGCGC 244 237 791 Antisense
CCGCGCAATTTGTCGTCGAGCTGAA 506 261 810 Antisense
TTCTATTTGTTCTCGGTCGTACTGC 330 687 911 Antisense
Sequence Source Affymetrix Proprietary Database