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[184594_at] 7TM receptor, sre family

Description Y57A10B.4 /REP_DB=WormBase Gene ID /WP=CE20325 /TR=Q9XWH7 /GB=CAA21691.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_total > 40      4grp_total > 18      6grp_cgc > 72      6grp_cgc_sub > 02      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 58
1 2 3 4 range
A 5.7
(-2.2)
A 		9.8
(-0.7)
A 		3.4
(-3)
A 		20
(3)
A 		17
B 3.3
(-3)
A 		3.2
(-3)
A 		7
(-2.2)
A 		30.9
(3)
A 		28
C 3.3
(-3)
A 		35.2
(0.3)
A 		9.9
(-2.3)
A 		61.4
(3)
A 		58
avr 4.1
(-3) 		16.1
(-0.8) 		6.8
(-2.5) 		37.4
(3) 		33

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 38
1 2 3 4 5 6 range
A 12
(-0.9)
A 		13.6
(-0.4)
A 		25.7
(3)
A 		7.2
(-2.2)
A 		4.4
(-3)
A 		23.1
(2.3)
A 		21
B 37.4
(3)
A 		34.8
(2.5)
A 		8
(-2.5)
A 		6.6
(-2.7)
A 		5.4
(-2.9)
A 		5.1
(-3)
A 		32
C 2.2
(-3)
A 		13.7
(-1.2)
A 		21.7
(0.1)
A 		40.4
(3)
A 		6.3
(-2.4)
A 		5.8
(-2.4)
A 		38
avr 17.2
(1.6) 		20.7
(3) 		18.5
(2.1) 		18.1
(2) 		5.4
(-3) 		11.3
(-0.7) 		15
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10
1 2 3 4 range
A 2.1
(0.6)
A 		2.1
(0.6)
A 		0.9
(-3)
A 		2.9
(3)
A 		2
B 1.1
(-2.7)
A 		0.8
(-3)
A 		1.6
(-2.2)
A 		6.6
(3)
A 		6
C 1.1
(-3)
A 		10.1
(2.9)
A 		3.4
(-1.5)
A 		10.3
(3)
A 		9
avr 1.4
(-3) 		4.3
(0.3) 		2
(-2.3) 		6.6
(3) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 12
1 2 3 4 5 6 range
A 2.2
(-1.7)
A 		4.8
(1.9)
A 		5.6
(3)
A 		1.8
(-2.3)
A 		1.3
(-3)
A 		5.6
(3)
A 		4
B 13
(3)
A 		11.6
(2.3)
A 		1.9
(-2.9)
A 		1.7
(-3)
A 		2.2
(-2.7)
A 		1.9
(-2.9)
A 		11
C 0.8
(-3)
A 		4.2
(-0.2)
A 		5.5
(0.9)
A 		8.1
(3)
A 		2
(-2)
A 		1.9
(-2.1)
A 		7
avr 5.3
(1.1) 		6.9
(3) 		4.3
(-0.1) 		3.9
(-0.5) 		1.8
(-3) 		3.1
(-1.5) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 184594_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2993
Sequence Type Exemplar sequence
Representative Public ID Y57A10B.4 NCBI
Target Description Y57A10B.4 /REP_DB=WormBase Gene ID /WP=CE20325 /TR=Q9XWH7 /GB=CAA21691.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064226(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064226 NCBI Caenorhabditis elegans Serpentine Receptor, class E (epsilon) family member (sre-42) (sre-42) mRNA, complete cds. 11/11 None
SNAP00000034313 ENSEMBL cdna:SNAP chromosome:CEL140:II:12383061:12386595:-1 11/11 None
GENEFINDER00000034320 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:12385148:12387613:-1 11/11 None
Y57A10B.4 ENSEMBL cdna:known chromosome:CEL140:II:12384532:12386784:-1 gene:Y57A10B.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:12385144-12387610(-) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor, sre family
Gene Symbol sre-42
Ensembl Y57A10B.4
Entrez Gene 190344 Entrez gene
SwissProt Q9XWH7 EMBL-EBI
WormBase CE37942 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
7606 sensory perception of chemical stimulus inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA21691 Hypothetical protein Y57A10B.4 [Caenorhabditis elegans] ref|NP_496627.2| Serpentine Receptor, class E (epsilon) family member (sre-42) [Caenorhabditis elegans] 1.0E-174
blast CAA21691 Hypothetical protein Y57A10B.4 [Caenorhabditis elegans] ref|NP_496627.2| Serpentine Receptor, class E (epsilon) family member (sre-42) [Caenorhabditis elegans] 1.0E-154
blast CAA21691 Hypothetical protein Y57A10B.4 [Caenorhabditis elegans] ref|NP_496627.2| Serpentine Receptor, class E (epsilon) family member (sre-42) [Caenorhabditis elegans] 1.0E-117
blast CAB02947 Hypothetical protein F15A4.3 [Caenorhabditis elegans] ref|NP_496655.2| Serpentine Receptor, class E (epsilon) family member (sre-37) [Caenorhabditis elegans] sp|O17818|SRE37_CAEEL Serpentine receptor class epsilon-37 (Protein sre-37) 1.0E-67
blast CAE73495 Hypothetical protein CBG20952 [Caenorhabditis briggsae] 1.0E-67
blast CAE73495 Hypothetical protein CBG20952 [Caenorhabditis briggsae] 2.0E-67
blast CAA21692 Hypothetical protein Y57A10B.5 [Caenorhabditis elegans] ref|NP_496628.1| Serpentine Receptor, class E (epsilon) family member (sre-41) [Caenorhabditis elegans] 4.0E-62
Protein Domains
Database ID Description E-Value
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 3.5E-84
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 3.3E-47
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 5.5E-69
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496627.2 7 26-48,65-87,126-148,168-190,195-217,259-281,286-308
Y57A10B.4 7 26-48,65-87,126-148,168-190,195-217,259-281,286-308
SNAP00000034313 4 2-24,63-85,105-127,132-154
GENEFINDER00000034320 7 49-66,86-108,125-147,186-208,228-250,255-277,319-341
Sequence
Target Sequence 
>C. ELEGANS:184594_AT
aaatacccggatagagcctacttcgcctggtggactgaagatcgggagaagatggttttg
gtagatgatctgaaagatattatggacctatacgtggcgagttgttttatgtggcattat
atttattcggtgattttcgcaccggtcgttgtgattgtagaacggggaatagcaacttgg
tatattcaagattatgagaatgtgcgtcgacgtcatattccaattctcctaatcatcgtc
accaacctgatcacaattccctatgctcatttcattatcaataatcgaatcccatttttg
atcgcatatgcgcaatgtgttctaaacgcgggtttcgtgttttttggatacagtatatca
tggaaagtacacgcgagatggaggaaacaaatggacgagccgcagacggatggtgagc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAATACCCGGATAGAGCCTACTTCG 49 115 481 Antisense
TCGCCTGGTGGACTGAAGATCGGGA 573 597 503 Antisense
ATGGACCTATACGTGGCGAGTTGTT 451 51 562 Antisense
ATTTTCGCACCGGTCGTTGTGATTG 572 13 613 Antisense
TGTGCGTCGACGTCATATTCCAATT 619 555 681 Antisense
TATTCCAATTCTCCTAATCATCGTC 117 665 696 Antisense
TAATCATCGTCACCAACCTGATCAC 394 635 710 Antisense
CACAATTCCCTATGCTCATTTCATT 151 195 732 Antisense
AATCGAATCCCATTTTTGATCGCAT 214 169 763 Antisense
GATCGCATATGCGCAATGTGTTCTA 549 417 780 Antisense
GACGAGCCGCAGACGGATGGTGAGC 422 379 874 Antisense
Sequence Source Affymetrix Proprietary Database