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[184528_at]

Description F45C12.1 /REP_DB=WormBase Gene ID /WP=CE10436 /TR=O16751 /GB=AAB66201.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_total > 49      4grp_total > 22      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 38
1 2 3 4 range
A 41.8
(3)
A 		28.5
(0.9)
A 		3.6
(-3)
A 		40.4
(2.8)
A 		38
B 26.2
(-3)
A 		26.4
(-2.8)
A 		34.1
(3)
A 		31.1
(0.7)
A 		8
C 22.3
(3)
A 		8.8
(-3)
A 		15.2
(-0.2)
A 		17.8
(1)
A 		14
avr 30.1
(3) 		21.2
(-1.3) 		17.6
(-3) 		29.8
(2.9) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 31
1 2 3 4 5 6 range
A 7.2
(-1.8)
A 		5.5
(-2.8)
A 		9.1
(-0.6)
A 		5.1
(-3)
A 		15.2
(3)
A 		14.7
(2.7)
A 		10
B 26.9
(3)
A 		11
(-1.5)
A 		5.7
(-3)
A 		7.4
(-2.5)
A 		15.8
(-0.1)
A 		20.1
(1.1)
A 		21
C 20.4
(0.7)
A 		19.9
(0.6)
A 		32.4
(3)
A 		1.4
(-3)
A 		27.6
(2.1)
A 		20.9
(0.8)
M 		31
avr 18.2
(2.5) 		12.1
(0) 		15.7
(1.5) 		4.6
(-3) 		19.5
(3) 		18.6
(2.6) 		15
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 15.2
(3)
A 		6.2
(-0.8)
A 		0.9
(-3)
A 		5.9
(-0.9)
A 		14
B 8.4
(3)
A 		6.5
(-3)
A 		7.9
(1.4)
A 		6.6
(-2.7)
A 		2
C 7.4
(3)
A 		2.5
(-3)
A 		5.3
(0.4)
A 		3
(-2.4)
A 		5
avr 10.3
(3) 		5.1
(-2.6) 		4.7
(-3) 		5.2
(-2.5) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 9
1 2 3 4 5 6 range
A 1.3
(-3)
A 		1.9
(-1.9)
A 		2
(-1.7)
A 		1.3
(-3)
A 		4.6
(3)
A 		3.6
(1.2)
A 		3
B 9.4
(3)
A 		3.7
(-1.3)
A 		1.4
(-3)
A 		2
(-2.6)
A 		6.4
(0.8)
A 		7.5
(1.6)
A 		8
C 7.5
(2)
A 		6.1
(1)
A 		8.2
(2.5)
A 		0.3
(-3)
A 		8.9
(3)
A 		7
(1.7)
M 		9
avr 6.1
(2.4) 		3.9
(0) 		3.9
(0) 		1.2
(-3) 		6.6
(3) 		6
(2.3) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 184528_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4547
Sequence Type Exemplar sequence
Representative Public ID F45C12.1 NCBI
Target Description F45C12.1 /REP_DB=WormBase Gene ID /WP=CE10436 /TR=O16751 /GB=AAB66201.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061663(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061663 NCBI Caenorhabditis elegans F45C12.1 (F45C12.1) mRNA, complete cds. 11/11 None
SNAP00000024790 ENSEMBL cdna:SNAP chromosome:CEL140:II:1739605:1740844:1 11/11 None
F45C12.1 ENSEMBL cdna:known chromosome:CEL140:II:1739079:1740844:1 gene:F45C12.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:1739077-1740843(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl F45C12.1
Entrez Gene 185765 Entrez gene
SwissProt O16751 EMBL-EBI
WormBase CE10436 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
4714 transmembrane receptor protein tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5006 epidermal growth factor receptor activity inferred from electronic annotation QuickGO AmiGO
8270 zinc ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB66201 Hypothetical protein F45C12.1 [Caenorhabditis elegans] ref|NP_494064.1| F45C12.1 [Caenorhabditis elegans] 0.0
blast AAB66201 Hypothetical protein F45C12.1 [Caenorhabditis elegans] ref|NP_494064.1| F45C12.1 [Caenorhabditis elegans] 1.0E-174
blast AAF39996 Hypothetical protein ZK355.4 [Caenorhabditis elegans] ref|NP_494402.1| ZK355.4 [Caenorhabditis elegans] 9.0E-99
blast AAM34815 Hypothetical protein T11F1.7 [Caenorhabditis elegans] ref|NP_494406.1| T11F1.7 [Caenorhabditis elegans] 3.0E-95
blast AAM34815 Hypothetical protein T11F1.7 [Caenorhabditis elegans] ref|NP_494406.1| T11F1.7 [Caenorhabditis elegans] 2.0E-72
blast AAF39996 Hypothetical protein ZK355.4 [Caenorhabditis elegans] ref|NP_494402.1| ZK355.4 [Caenorhabditis elegans] 2.0E-69
Protein Domains
Database ID Description E-Value
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 1.1E-30
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 1.0E-6
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 1.1E-30
Pfam IPR000494 EMBL-EBI Epidermal growth-factor receptor (EGFR), L domain 1.0E-6
Sequence
Target Sequence 
>C. ELEGANS:184528_AT
cacatctaagattaccgctgctggaaagaattgaaaatatgctcagtggtgctttgatat
tcaatgtggaaaacgtgcaccctgacttttgtttcaatgtcgacgaactacatatgcatc
tcgaccttgaaatccaatttcaaaatttacacgcaacatattgtcctgactttgaaaatt
ccggccggattcacagagcttgtaaattccaacaattgagctctctggagaagggctgca
cgggaatttatggagatattgttgtagatgtaaacgatgggcgctacttgcataagctgt
tcttgcttcagtacttgtacgggtcgctgaaaattcagtatatgaaggctgacggattgg
actttttgagttccttgatttacattgccgccttggatgggaccaggcctgcagtcttga
ttcggtccaacaagtatttgaagcaagcggcgatacctaggcttttgaccatcatatcca
cctacccggaacctgtggtcctctacgacaaccccgctttgttcagcgataa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CACATCTAAGATTACCGCTGCTGGA 453 195 839 Antisense
TGCACCCTGACTTTTGTTTCAATGT 647 577 914 Antisense
GAACTACATATGCATCTCGACCTTG 41 351 943 Antisense
TCCGGCCGGATTCACAGAGCTTGTA 299 593 1018 Antisense
CTCTCTGGAGAAGGGCTGCACGGGA 510 229 1059 Antisense
GGGCGCTACTTGCATAAGCTGTTCT 155 493 1117 Antisense
TGTTCTTGCTTCAGTACTTGTACGG 86 563 1136 Antisense
TGAGTTCCTTGATTTACATTGCCGC 368 567 1205 Antisense
TTGCCGCCTTGGATGGGACCAGGCC 508 699 1223 Antisense
CGGCGATACCTAGGCTTTTGACCAT 273 239 1286 Antisense
ACAACCCCGCTTTGTTCAGCGATAA 682 111 1346 Antisense
Sequence Source Affymetrix Proprietary Database