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[184341_at]

Description C35D10.8 /REP_DB=WormBase Gene ID /WP=CE01202 /TR=Q18481 /GB=AAA62565.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_high1_10_10 > 89      6grp_total > 59      4grp_total > 21      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 74
1 2 3 4 range
A 37
(-1.1)
P 		65.4
(1.7)
A 		17.3
(-3)
A 		78.7
(3)
A 		61
B 78.1
(0.7)
P 		59.3
(-3)
A 		62.2
(-2.4)
P 		89.6
(3)
P 		30
C 90.9
(3)
P 		41.1
(-2)
A 		31.1
(-3)
A 		76.2
(1.5)
P 		60
avr 68.7
(1.3) 		55.3
(-0.5) 		36.9
(-3) 		81.5
(3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 102
1 2 3 4 5 6 range
A 103.7
(0.9)
P 		56.2
(-3)
P 		63.3
(-2.4)
P 		85.4
(-0.6)
P 		129.4
(3)
P 		123.2
(2.5)
P 		73
B 69.7
(-2.2)
P 		78
(-1.6)
P 		57
(-3)
P 		66.4
(-2.4)
A 		148.4
(3)
P 		119.7
(1.1)
P 		91
C 130
(2.8)
P 		71.8
(-1.2)
P 		46.5
(-3)
A 		110.3
(1.4)
P 		81.9
(-0.5)
P 		132.7
(3)
P 		86
avr 101.1
(0.9) 		68.7
(-1.9) 		55.6
(-3) 		87.4
(-0.3) 		119.9
(2.5) 		125.2
(3) 		70
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 26
1 2 3 4 range
A 13.5
(2.6)
P 		14.2
(3)
A 		4.5
(-3)
A 		11.5
(1.3)
A 		10
B 24.9
(3)
P 		14.7
(-2.8)
A 		14.4
(-3)
P 		19.1
(-0.3)
P 		11
C 30.1
(3)
P 		11.8
(-2.7)
A 		10.9
(-3)
A 		12.8
(-2.4)
P 		19
avr 22.8
(3) 		13.6
(-1.3) 		9.9
(-3) 		14.5
(-0.9) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 19.1
(-1.7)
P 		20
(-1.5)
P 		13.8
(-3)
P 		21.7
(-1.1)
P 		39
(3)
P 		30
(0.9)
P 		25
B 24.2
(-1.7)
P 		26
(-1.4)
P 		13.8
(-3)
P 		17.6
(-2.5)
A 		60.3
(3)
P 		44.6
(1)
P 		47
C 48.2
(3)
P 		21.9
(-1.3)
P 		11.8
(-3)
A 		22.2
(-1.3)
P 		26.5
(-0.6)
P 		44.4
(2.4)
P 		36
avr 30.5
(0.6) 		22.6
(-1) 		13.1
(-3) 		20.5
(-1.5) 		41.9
(3) 		39.7
(2.5) 		29
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 184341_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6655
Sequence Type Exemplar sequence
Representative Public ID C35D10.8 NCBI
Target Description C35D10.8 /REP_DB=WormBase Gene ID /WP=CE01202 /TR=Q18481 /GB=AAA62565.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_065607(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_065607 NCBI Caenorhabditis elegans C35D10.8 (C35D10.8) mRNA, complete cds. 11/11 None
SNAP00000029542 ENSEMBL cdna:SNAP chromosome:CEL140:III:4852286:4856033:1 11/11 None
GENEFINDER00000029570 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:4852286:4860647:1 11/11 None
C35D10.8 ENSEMBL cdna:known chromosome:CEL140:III:4855288:4856033:1 gene:C35D10.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:4855044-4856033(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl C35D10.8
Entrez Gene 183239 Entrez gene
SwissProt Q18481 EMBL-EBI
WormBase CE29702 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_001021203 CEll Death abnormality family member (ced-4) [Caenorhabditis elegans] gb|AAX22294.1| Cell death abnormality protein 4, isoform b [Caenorhabditis elegans] sp|P30429|CED4_CAEEL Cell death protein 0.0
blast CAA48781 ced-4 [Caenorhabditis elegans] ref|NP_001021202.1| CEll Death abnormality family member (ced-4) [Caenorhabditis elegans] gb|AAA62564.1| Cell death abnormality protein 4, isoform a [Caenorhabditis elegans] 0.0
blast Q60Z52 Cell death protein 4 emb|CAE71110.1| Hypothetical protein CBG17963 [Caenorhabditis briggsae] 0.0
blast NP_498009 C35D10.7a [Caenorhabditis elegans] gb|AAN63435.1| Hypothetical protein C35D10.7a [Caenorhabditis elegans] 0.0
blast NP_498008 C35D10.8 [Caenorhabditis elegans] gb|AAA62565.2| Hypothetical protein C35D10.8 [Caenorhabditis elegans] 1.0E-80
blast CAE71109 Hypothetical protein CBG17962 [Caenorhabditis briggsae] 2.0E-40
Protein Domains
Database ID Description E-Value
Pfam IPR002182 EMBL-EBI NB-ARC domain 1.1E-38
Pfam IPR002182 EMBL-EBI NB-ARC domain 2.9E-87
Pfam IPR001315 EMBL-EBI CARD interaction domain 8.6E-24
Pfam IPR001395 EMBL-EBI Aldo/keto reductase 1.1E-110
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_498008.2 2 7-29,39-58
C35D10.8 2 7-29,39-58
SNAP00000029542 2 561-583,590-612
GENEFINDER00000029570 6 552-574,587-609,614-636,787-809,1360-1379,1386-1408
Sequence
Target Sequence 
>C. ELEGANS:184341_AT
aagatgttcgatttctttcctctgttggcgtcattactacatttgctttgctgcttcact
ttatcgagattcttgccatcaatggagttccatctagaccgatagcagtcttcatatcat
tatccctgtatatttggttcactgttttcggtcaatgggtgacacgtgctcgacgagcaa
ttttcaacgaacgcaatctcctagtcacttatcaaccaagagccctcacccatggacatc
tctttgtgccagatccgccgacgccttgtcgtctgtccattacaccatgtgaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGATGTTCGATTTCTTTCCTCTGT 491 155 143 Antisense
TCCTCTGTTGGCGTCATTACTACAT 687 591 160 Antisense
ACTACATTTGCTTTGCTGCTTCACT 434 101 178 Antisense
GCTGCTTCACTTTATCGAGATTCTT 53 297 192 Antisense
TGGAGTTCCATCTAGACCGATAGCA 504 549 225 Antisense
TAGCAGTCTTCATATCATTATCCCT 61 653 245 Antisense
ATATTTGGTTCACTGTTTTCGGTCA 329 19 272 Antisense
GTCAATGGGTGACACGTGCTCGACG 314 463 293 Antisense
GCAATCTCCTAGTCACTTATCAACC 14 323 335 Antisense
TCACCCATGGACATCTCTTTGTGCC 513 625 368 Antisense
TCGTCTGTCCATTACACCATGTGAA 327 605 411 Antisense
Sequence Source Affymetrix Proprietary Database