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[183917_at]

Description C24H11.7 /REP_DB=WormBase Gene ID /WP=CE19701 /TR=Q9XTF0 /GB=CAA21551.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_high1_10_10 > 18      4grp_high_8_8 > 43      6grp_total > 06      4grp_total > 52      6grp_cgc > 12      6grp_cgc_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 132
1 2 3 4 range
A 242
(3)
P 		219.3
(1.5)
P 		201.8
(0.3)
P 		154
(-3)
A 		88
B 228.9
(3)
P 		224.8
(2.8)
P 		181.4
(0.3)
P 		121.7
(-3)
P 		107
C 238.4
(2.4)
P 		250.8
(3)
P 		224.1
(1.8)
P 		118.5
(-3)
A 		132
avr 236.4
(3) 		231.6
(2.7) 		202.4
(1.1) 		131.4
(-3) 		105

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 289
1 2 3 4 5 6 range
A 169.8
(-0.3)
P 		251.2
(3)
P 		101.4
(-3)
P 		192.5
(0.6)
P 		156
(-0.8)
P 		180.4
(0.2)
P 		150
B 105.7
(-1.3)
P 		125.5
(2.9)
P 		126.2
(3)
P 		125.4
(2.8)
P 		97.6
(-3)
P 		99.5
(-2.6)
P 		29
C 382.1
(3)
P 		132
(-2.2)
P 		203.2
(-0.7)
P 		92.7
(-3)
A 		228.7
(-0.2)
P 		127.4
(-2.3)
A 		289
avr 219.2
(3) 		169.6
(-0.6) 		143.6
(-2.4) 		136.9
(-2.9) 		160.8
(-1.2) 		135.8
(-3) 		83
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 68
1 2 3 4 range
A 88.1
(3)
P 		47.6
(-0.7)
P 		52.8
(-0.2)
P 		22.5
(-3)
A 		66
B 73
(3)
P 		55.5
(0.8)
P 		42
(-0.9)
P 		25.9
(-3)
P 		47
C 78.9
(3)
P 		72.1
(2.3)
P 		78.1
(2.9)
P 		20
(-3)
A 		59
avr 80
(3) 		58.4
(0.7) 		57.6
(0.7) 		22.8
(-3) 		57

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 123
1 2 3 4 5 6 range
A 31.3
(-2.2)
P 		89.3
(3)
P 		22.1
(-3)
P 		48.8
(-0.6)
P 		47.1
(-0.8)
P 		43.9
(-1.1)
P 		67
B 36.8
(0.3)
P 		41.8
(3)
P 		30.6
(-3)
P 		33.2
(-1.6)
P 		39.7
(1.9)
P 		37.1
(0.5)
P 		11
C 141.6
(3)
P 		40.3
(-1.9)
P 		51.7
(-1.4)
P 		18.6
(-3)
A 		74
(-0.3)
P 		42.6
(-1.8)
A 		123
avr 69.9
(3) 		57.1
(0.9) 		34.8
(-2.8) 		33.5
(-3) 		53.6
(0.3) 		41.2
(-1.7) 		36
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 183917_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6441
Sequence Type Exemplar sequence
Representative Public ID C24H11.7 NCBI
Target Description C24H11.7 /REP_DB=WormBase Gene ID /WP=CE19701 /TR=Q9XTF0 /GB=CAA21551.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067121(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067121 NCBI Caenorhabditis elegans GBF1(Golgi-specific Brefeldin-A-resistant Factor 1) homolog family member (gbf-1) (gbf-1) mRNA, complete cds. 11/11 None
GENEFINDER00000034902 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:11751456:11755391:-1 11/11 None
C24H11.7 ENSEMBL cdna:known chromosome:CEL140:III:11754157:11773537:-1 gene:C24H11.7 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:11754152-11773533(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol gbf-1
Ensembl C24H11.7
Entrez Gene 176609 Entrez gene
SwissProt Q9XTF0 EMBL-EBI
WormBase CE19701 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:262614_AT pattern formation protein (EMB30) (GNOM) at
ATGENOME1:15650_S_AT pattern formation protein (EMB30) (GNOM) at
CANINE_2:CFAAFFX.15865.1.S1_S_AT similar to Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) cfa
DROSOPHILA_2:1636686_AT gartenzwerg dm
DROSOPHILA_2:1639361_A_AT gartenzwerg dm
DROSOPHILA_2:1626339_AT gartenzwerg dm
DROSGENOME1:147079_AT gartenzwerg dm
CHICKEN:GGA.6986.1.S1_AT similar to Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) gga
CHICKEN:GGAAFFX.26551.1.S1_S_AT similar to Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) gga
CHICKEN:GGAAFFX.26551.2.S1_AT similar to Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) gga
CHICKEN:GGAAFFX.26551.2.S1_S_AT similar to Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) gga
HG-U133A:201439_AT golgi-specific brefeldin A resistance factor 1 hs
HG-U133A_2:201439_AT golgi-specific brefeldin A resistance factor 1 hs
HG-U133_PLUS_2:201439_AT golgi-specific brefeldin A resistance factor 1 hs
HG-FOCUS:201439_AT golgi-specific brefeldin A resistance factor 1 hs
HU35KSUBA:HUM_ALU_AT golgi-specific brefeldin A resistance factor 1 hs
HU35KSUBB:HUM_ALU_AT golgi-specific brefeldin A resistance factor 1 hs
HU35KSUBC:HUM_ALU_AT golgi-specific brefeldin A resistance factor 1 hs
HU35KSUBD:HUM_ALU_AT golgi-specific brefeldin A resistance factor 1 hs
HUGENEFL:HUM_ALU_AT golgi-specific brefeldin A resistance factor 1 hs
HC-G110:HUM_ALU_AT golgi-specific brefeldin A resistance factor 1 hs
HUGENEFL:D87435_AT golgi-specific brefeldin A resistance factor 1 hs
U133_X3P:G4758415_3P_AT golgi-specific brefeldin A resistance factor 1 hs
HG-U95AV2:40123_AT golgi-specific brefeldin A resistance factor 1 hs
HG-U133_PLUS_2:233114_AT Golgi-specific brefeldin A resistance factor 1 hs
HG-U133B:233114_AT Golgi-specific brefeldin A resistance factor 1 hs
U133_X3P:HS2.384696.1.S1_3P_AT Golgi-specific brefeldin A resistance factor 1 hs
U133_X3P:HS2.376268.1.S1_3P_X_AT Golgi-specific brefeldin A resistance factor 1 hs
U133_X3P:HS2.376268.1.S1_3P_AT Golgi-specific brefeldin A resistance factor 1 hs
U133_X3P:HS.301836.0.S1_3P_AT Golgi-specific brefeldin A resistance factor 1 hs
U133_X3P:233114_3P_AT Golgi-specific brefeldin A resistance factor 1 hs
U133_X3P:1566142_3P_AT Golgi-specific brefeldin A resistance factor 1 hs
HG-U133_PLUS_2:1561154_AT Golgi-specific brefeldin A resistance factor 1 hs
HG-U133_PLUS_2:1566142_AT Golgi-specific brefeldin A resistance factor 1 hs
HG-U95E:71710_AT Golgi-specific brefeldin A resistance factor 1 hs
HG-U133_PLUS_2:1566141_AT Golgi-specific brefeldin A resistance factor 1 hs
HG-U95C:57512_AT Golgi-specific brefeldin A resistance factor 1 hs
HG-U95E:70245_AT Golgi-specific brefeldin A resistance factor 1 hs
HG-U95E:85615_R_AT Golgi-specific brefeldin A resistance factor 1 hs
MG-U74AV2:102003_AT golgi-specific brefeldin A-resistance factor 1 mm
MG-U74BV2:107292_AT golgi-specific brefeldin A-resistance factor 1 mm
MG-U74BV2:165206_R_AT golgi-specific brefeldin A-resistance factor 1 mm
MOE430A:1415709_S_AT golgi-specific brefeldin A-resistance factor 1 mm
MOE430B:1415709_S_AT golgi-specific brefeldin A-resistance factor 1 mm
MOUSE430A_2:1415709_S_AT golgi-specific brefeldin A-resistance factor 1 mm
MOUSE430_2:1415709_S_AT golgi-specific brefeldin A-resistance factor 1 mm
MOE430A:1415757_AT golgi-specific brefeldin A-resistance factor 1 mm
MOE430B:1415757_AT golgi-specific brefeldin A-resistance factor 1 mm
MOUSE430A_2:1415757_AT golgi-specific brefeldin A-resistance factor 1 mm
MOUSE430_2:1415757_AT golgi-specific brefeldin A-resistance factor 1 mm
MOE430B:1438207_AT golgi-specific brefeldin A-resistance factor 1 mm
MOUSE430_2:1438207_AT golgi-specific brefeldin A-resistance factor 1 mm
MOE430B:1432677_AT Golgi-specific brefeldin A-resistance factor 1, mRNA (cDNA clone IMAGE:4981388) mm
MOUSE430_2:1432677_AT Golgi-specific brefeldin A-resistance factor 1, mRNA (cDNA clone IMAGE:4981388) mm
MU19KSUBA:TC24199_AT Golgi-specific brefeldin A-resistance factor 1, mRNA (cDNA clone IMAGE:4981388) mm
RAE230A:1389044_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RAT230_2:1389044_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RG-U34B:RC_AA924964_G_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RG-U34B:RC_AI044908_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RG-U34B:RC_AA924964_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RAE230A:1390611_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RAT230_2:1390611_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RAE230B:1385077_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RAT230_2:1385077_AT similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RAE230B:1380122_AT Similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
RAT230_2:1380122_AT Similar to golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (predicted) rn
YEAST_2:1775459_AT Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea1p Sc
Protein Similarities
Method ID Description E-Value
blast CAA21551 Hypothetical protein C24H11.7 [Caenorhabditis elegans] emb|CAB03915.1| Hypothetical protein C24H11.7 [Caenorhabditis elegans] ref|NP_499522.1| GBF1(Golgi-specific Brefeldin-A-resistant Factor 1) homolog family member (gbf-1) [Caenorhabditis elegans] 0.0
blast CAE67661 Hypothetical protein CBG13224 [Caenorhabditis briggsae] 0.0
blast XP_219953 PREDICTED: similar to Golgi-specific brefeldin A-resistance factor 1 [Rattus norvegicus] 0.0
blast CAA21551 Hypothetical protein C24H11.7 [Caenorhabditis elegans] emb|CAB03915.1| Hypothetical protein C24H11.7 [Caenorhabditis elegans] ref|NP_499522.1| GBF1(Golgi-specific Brefeldin-A-resistant Factor 1) homolog family member (gbf-1) [Caenorhabditis elegans] 5.0E-99
blast CAE67661 Hypothetical protein CBG13224 [Caenorhabditis briggsae] 3.0E-71
blast XP_421632 PREDICTED: similar to Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) [Gallus gallus] 4.0E-30
Protein Domains
Database ID Description E-Value
Pfam IPR000904 EMBL-EBI SEC7-like domain 1.8E-67
Sequence
Target Sequence 
>C. ELEGANS:183917_AT
ttcccattgctcactaagcttctggagccattctctcaaatggatccgattggaatggag
gatacacgtgttcggacacttcaaatcgtcgcgaaaactcttttaaatcatctctcagcc
ctgtcggctcttgattcattcccggatctttggatgcttctgctcgactatatggagcaa
tatcttcgagttgatagctgtggaaatttgaatgaagcagtgccggaatcgctgaaaaat
atgcttctcgttatggatagtacgggaattttcgctgcaacacctcggctttatgatgtg
actgtggagaggctcaacaaatttatgcccgaattgattaaggatacgattccgaatcca
ccacggccagggcagcagcagtcggaagcgtcggagccgaagaaggagcatgcttctggg
cttgagccaccaccaccatcatccaactcaacagccgccacttcaacatctgatccttcg
atcgctactgcacaatcttcaatttcgacagcttcatctgttgttggaccact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCCCATTGCTCACTAAGCTTCTGG 695 697 4861 Antisense
AGCTTCTGGAGCCATTCTCTCAAAT 323 79 4877 Antisense
CTCTTTTAAATCATCTCTCAGCCCT 58 231 4958 Antisense
GATTCATTCCCGGATCTTTGGATGC 339 431 4993 Antisense
TGGATGCTTCTGCTCGACTATATGG 69 551 5011 Antisense
GTACGGGAATTTTCGCTGCAACACC 693 457 5120 Antisense
CTGCAACACCTCGGCTTTATGATGT 156 239 5135 Antisense
GAAGGAGCATGCTTCTGGGCTTGAG 150 335 5262 Antisense
AACATCTGATCCTTCGATCGCTACT 47 139 5325 Antisense
AATCTTCAATTTCGACAGCTTCATC 145 171 5354 Antisense
CAGCTTCATCTGTTGTTGGACCACT 43 205 5369 Antisense
Sequence Source Affymetrix Proprietary Database