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[183837_s_at]

Description W08F4.8 /REP_DB=WormBase Gene ID /WP=CE14726 /TR=O02108 /GB=AAC71172.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 98      6grp_high1_10_10 > 89      4grp_highest_8_8 > 18      4grp_high_8_8 > 62      6grp_highest_nonorm > 81      6grp_total > 89      4grp_total > 58      6grp_highest_sub > Cu      6grp_high1_sub > Cu      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 204
1 2 3 4 range
A 252.4
(-1.3)
P 		258.5
(-0.8)
P 		306.1
(3)
P 		231.8
(-3)
P 		74
B 232.9
(-2.6)
P 		287.9
(-0.1)
P 		355.9
(3)
P 		225.1
(-3)
P 		131
C 266.5
(1.1)
P 		319.3
(3)
P 		299.6
(2.3)
P 		152.1
(-3)
P 		167
avr 250.6
(-0.6) 		288.6
(1.4) 		320.5
(3) 		203
(-3) 		118

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 221
1 2 3 4 5 6 range
A 204.1
(-2.8)
P 		336.9
(2)
P 		198.3
(-3)
P 		250.3
(-1.1)
P 		259.7
(-0.8)
P 		363.4
(3)
P 		165
B 216.8
(-1.9)
P 		202.3
(-3)
P 		212.5
(-2.2)
P 		211.9
(-2.2)
P 		260.4
(1.6)
P 		278.4
(3)
P 		76
C 387.5
(2.9)
P 		169.2
(-3)
P 		231.9
(-1.3)
P 		204.8
(-2)
P 		390
(3)
P 		312.4
(0.9)
P 		221
avr 269.5
(0.2) 		236.1
(-1.7) 		214.2
(-3) 		222.3
(-2.5) 		303.4
(2.2) 		318.1
(3) 		104
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 79
1 2 3 4 range
A 91.9
(3)
P 		56.1
(-0.7)
P 		80
(1.8)
P 		33.9
(-3)
P 		58
B 74.3
(1.6)
P 		71.1
(1)
P 		82.5
(3)
P 		48
(-3)
P 		35
C 88.2
(1.8)
P 		91.8
(2)
P 		104.4
(3)
P 		25.6
(-3)
P 		79
avr 84.8
(2.5) 		73
(1.2) 		89
(3) 		35.8
(-3) 		53

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 106
1 2 3 4 5 6 range
A 37.6
(-3)
P 		119.8
(3)
P 		43.2
(-2.6)
P 		63.5
(-1.1)
P 		78.4
(-0)
P 		88.5
(0.7)
P 		82
B 75.4
(-0.4)
P 		67.3
(-1.3)
P 		51.6
(-3)
P 		56.1
(-2.5)
P 		105.8
(3)
P 		103.8
(2.8)
P 		54
C 143.6
(3)
P 		51.6
(-2.4)
P 		59
(-2)
P 		41.2
(-3)
P 		126.2
(2)
P 		104.6
(0.7)
P 		102
avr 85.5
(0.9) 		79.6
(0.3) 		51.3
(-3) 		53.6
(-2.7) 		103.5
(3) 		99
(2.5) 		52
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 183837_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.5481
Sequence Type Exemplar sequence
Representative Public ID W08F4.8 NCBI
Target Description W08F4.8 /REP_DB=WormBase Gene ID /WP=CE14726 /TR=O02108 /GB=AAC71172.1 /SUBMIT=ST.LOUIS /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061360(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061360 NCBI Caenorhabditis elegans W08F4.8 (W08F4.8) mRNA, complete cds. 11/11 None
SNAP00000029465 ENSEMBL cdna:SNAP chromosome:CEL140:II:578085:579883:-1 11/11 None
GENEFINDER00000029479 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:578085:579883:-1 11/11 None
W08F4.8.2 ENSEMBL cdna:known chromosome:CEL140:II:577802:579890:-1 gene:W08F4.8 11/11 None
W08F4.8.1 ENSEMBL cdna:known chromosome:CEL140:II:577837:580546:-1 gene:W08F4.8 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:578084-579883(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl W08F4.8
Entrez Gene 173449 Entrez gene
SwissProt O02108 EMBL-EBI
WormBase CE14726 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1586849_AT similar to Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) cfa
CANINE_2:CFA.10625.1.S1_AT similar to Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) cfa
CANINE_2:CFA.21589.1.S1_S_AT similar to Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) cfa
CANINE_2:CFAAFFX.27240.1.S1_S_AT similar to Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) cfa
CANINE_2:CFAAFFX.27245.1.S1_S_AT similar to Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) cfa
DROSOPHILA_2:1630283_AT Cdc37 dm
DROSGENOME1:143662_AT Cdc37 dm
HG-U95AV2:505_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
HC-G110:505_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
HG-U133_PLUS_2:209953_S_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
HG-U133A:209953_S_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
HG-FOCUS:209953_S_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
HG-U133A_2:209953_S_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
HUGENEFL:U43077_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
U133_X3P:G1421820_3P_A_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
HG-U95D:75062_AT CDC37 cell division cycle 37 homolog (S. cerevisiae) hs
MU11KSUBA:U43076_S_AT cell division cycle 37 homolog (S. cerevisiae) mm
MG-U74AV2:99135_AT cell division cycle 37 homolog (S. cerevisiae) mm
MG-U74BV2:105492_AT cell division cycle 37 homolog (S. cerevisiae) mm
MOE430A:1416819_AT cell division cycle 37 homolog (S. cerevisiae) mm
MOUSE430A_2:1416819_AT cell division cycle 37 homolog (S. cerevisiae) mm
MOUSE430_2:1416819_AT cell division cycle 37 homolog (S. cerevisiae) mm
MOE430A:1416820_AT cell division cycle 37 homolog (S. cerevisiae) mm
MOUSE430A_2:1416820_AT cell division cycle 37 homolog (S. cerevisiae) mm
MOUSE430_2:1416820_AT cell division cycle 37 homolog (S. cerevisiae) mm
RG-U34A:D26564_AT cell division cycle 37 homolog (S. cerevisiae) rn
RG-U34A:D26564_G_AT cell division cycle 37 homolog (S. cerevisiae) rn
RG-U34C:RC_AI234952_I_AT cell division cycle 37 homolog (S. cerevisiae) rn
RAE230A:1367453_AT cell division cycle 37 homolog (S. cerevisiae) rn
RAE230B:1367453_AT cell division cycle 37 homolog (S. cerevisiae) rn
RAT230_2:1367453_AT cell division cycle 37 homolog (S. cerevisiae) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
74 regulation of progression through cell cycle inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAC71172 Hypothetical protein W08F4.8 [Caenorhabditis elegans] ref|NP_493761.1| W08F4.8 [Caenorhabditis elegans] sp|O02108|CDC37_CAEEL Probable Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) 1.0E-169
blast CAE62901 Hypothetical protein CBG07091 [Caenorhabditis briggsae] 1.0E-139
Protein Domains
Database ID Description E-Value
Pfam IPR004918 EMBL-EBI Cdc37 family 8.4E-124
Sequence
Target Sequence 
>C. ELEGANS:183837_S_AT
ggagccaagtcgacggagctgttcctggccgagcatccgcatatggcgtcggagtacact
gcaaattggctcacaattgaggctctcaacgccgccatcgattttaatgaggagaaaatg
aagacgatggctgagcaatgcatcatcattcaatatcttctggagctctcgaaatcgctg
aacgcagtcgccacgaataccaccgtccagaagcaattcttcaagaagttcgaagccgcc
gagccggtctacatgaagcactatcaggatgaggtgaaggcgttcgaggatcgtctcaga
acacgtgcgcagacgaagagagacgccgcgatggaggaggctgaagccgaggagaaagcc
gaacgaatgaagagtgctccgggaggaatcgatccacaggaagtgttcgagcagctgccg
gaggagatgagaaagtgctttgaggcacatgatatcgaggcgttgaagggtgtcgcccag
aaaatggatgaagaggtcttcaagtaccatttcgatcgatgcatcgcctctggactctgg
gtgcccggaaaagctgacgacgacg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAGCCAAGTCGACGGAGCTGTTCC 364 521 508 Antisense
CCGAGCATCCGCATATGGCGTCGGA 244 261 536 Antisense
TCTCAACGCCGCCATCGATTTTAAT 71 613 591 Antisense
CATTCAATATCTTCTGGAGCTCTCG 563 215 654 Antisense
GGAGCTCTCGAAATCGCTGAACGCA 65 521 669 Antisense
GAGCCGGTCTACATGAAGCACTATC 26 387 748 Antisense
GAGGATCGTCTCAGAACACGTGCGC 652 403 793 Antisense
GTGCTCCGGGAGGAATCGATCCACA 635 479 881 Antisense
CAGGAAGTGTTCGAGCAGCTGCCGG 287 209 904 Antisense
GTCTTCAAGTACCATTTCGATCGAT 417 469 1003 Antisense
GTGCCCGGAAAAGCTGACGACGACG 548 473 1048 Antisense
Sequence Source Affymetrix Proprietary Database