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[183541_at] hexaprenyl pyrophosphate synthetase

Description C30H7.1 /REP_DB=WormBase Gene ID /WP=CE08477 /TR=O01491 /GB=AAB63408.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 33      6grp_high1_10_10 > 22      4grp_highest_8_8 > 33      4grp_high_8_8 > 58      6grp_highest_nonorm > 71      6grp_total > 22      4grp_total > 61      6grp_highest_sub > 02      6grp_cgc > 61      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Hat      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 314
1 2 3 4 range
A 324.8
(3)
P 		208.8
(-0.1)
P 		237.5
(0.7)
P 		101.4
(-3)
P 		223
B 371.5
(3)
P 		300
(1.5)
P 		329.7
(2.1)
P 		90.9
(-3)
P 		281
C 405.1
(3)
P 		323.4
(1.2)
P 		383
(2.5)
P 		136.3
(-3)
P 		269
avr 367.1
(3) 		277.4
(0.9) 		316.7
(1.8) 		109.5
(-3) 		258

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 362
1 2 3 4 5 6 range
A 228.2
(-2.3)
P 		417.8
(3)
P 		321.5
(0.3)
P 		301.8
(-0.2)
P 		249
(-1.7)
P 		203.2
(-3)
P 		215
B 333.9
(1.7)
P 		358.7
(2.3)
P 		384.6
(3)
P 		320.6
(1.4)
P 		267.7
(0)
P 		149.8
(-3)
P 		235
C 512.1
(3)
P 		394.9
(0.8)
P 		332.2
(-0.3)
P 		308.6
(-0.8)
P 		239.4
(-2.1)
P 		188.6
(-3)
P 		324
avr 358.1
(2.1) 		390.5
(3) 		346.1
(1.7) 		310.3
(0.7) 		252
(-1) 		180.5
(-3) 		210
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 119
1 2 3 4 range
A 118.3
(3)
P 		45.3
(-1.2)
P 		62.1
(-0.3)
P 		14.8
(-3)
P 		104
B 118.5
(3)
P 		74.1
(0.3)
P 		76.4
(0.5)
P 		19.4
(-3)
P 		99
C 134.1
(3)
P 		93
(0.8)
P 		133.5
(3)
P 		23
(-3)
P 		111
avr 123.6
(3) 		70.8
(-0) 		90.7
(1.1) 		19.1
(-3) 		105

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 148
1 2 3 4 5 6 range
A 42.1
(-3)
P 		148.6
(3)
P 		70
(-1.4)
P 		76.5
(-1.1)
P 		75.1
(-1.1)
P 		49.5
(-2.6)
P 		107
B 116.2
(2.7)
P 		119.4
(3)
P 		93.4
(0.5)
P 		84.9
(-0.3)
P 		108.8
(2)
P 		55.8
(-3)
P 		64
C 189.8
(3)
P 		120.5
(-0.3)
P 		84.6
(-1.9)
P 		62.1
(-3)
P 		77.5
(-2.3)
P 		63.1
(-3)
P 		128
avr 116
(1.9) 		129.5
(3) 		82.7
(-0.8) 		74.5
(-1.5) 		87.1
(-0.5) 		56.1
(-3) 		73
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 183541_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.897
Sequence Type Exemplar sequence
Representative Public ID C30H7.1 NCBI
Target Description C30H7.1 /REP_DB=WormBase Gene ID /WP=CE08477 /TR=O01491 /GB=AAB63408.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059187(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059187 NCBI Caenorhabditis elegans COenzyme Q (ubiquinone) biosynthesis family member (coq-1) (coq-1) mRNA, complete cds. 11/11 A 
SNAP00000026426 ENSEMBL cdna:SNAP chromosome:CEL140:I:5414499:5415538:-1 11/11 None
C24A11.9 ENSEMBL cdna:known chromosome:CEL140:I:5412869:5415632:-1 gene:C24A11.9 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000026429 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:5415052-5415538(-) 100.0 100.0
Public Domain and Genome References
Gene Title hexaprenyl pyrophosphate synthetase
Gene Symbol coq-1
Ensembl C24A11.9
Entrez Gene 172190 Entrez gene
SwissProt P91093 EMBL-EBI
WormBase CE29183 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:262526_AT geranyl diphosphate synthase, putative / GPPS, putative / dimethylallyltransferase, putative / prenyl transferase, putative at
CANINE_2:CFAAFFX.7413.1.S1_AT similar to trans-prenyltransferase cfa
DROSOPHILA_2:1641558_AT dm
DROSGENOME1:151113_AT dm
DROSGENOME1:150933_AT dm
CHICKEN:GGA.9924.1.S1_AT trans-prenyltransferase gga
HG-U133_PLUS_2:220865_S_AT trans-prenyltransferase hs
HG-U133A:220865_S_AT trans-prenyltransferase hs
HG-FOCUS:220865_S_AT trans-prenyltransferase hs
HG-U133A_2:220865_S_AT trans-prenyltransferase hs
U133_X3P:G11863164_3P_A_AT trans-prenyltransferase hs
HG-U95E:72483_AT trans-prenyltransferase hs
HG-U95E:91048_AT trans-prenyltransferase hs
HG-U133_PLUS_2:236298_AT Trans-prenyltransferase hs
HG-U133B:236298_AT Trans-prenyltransferase hs
HU35KSUBC:RC_H99626_AT Trans-prenyltransferase hs
MOE430A:1431893_A_AT trans-prenyltransferase mm
MOUSE430_2:1431893_A_AT trans-prenyltransferase mm
MOUSE430A_2:1431893_A_AT trans-prenyltransferase mm
MOUSE430_2:1454090_AT trans-prenyltransferase mm
MOE430A:1454090_AT trans-prenyltransferase mm
MOUSE430A_2:1454090_AT trans-prenyltransferase mm
MOE430A:1438506_S_AT Trans-prenyltransferase, mRNA (cDNA clone MGC:28441 IMAGE:4039464) mm
MOUSE430A_2:1438506_S_AT Trans-prenyltransferase, mRNA (cDNA clone MGC:28441 IMAGE:4039464) mm
MOUSE430_2:1438506_S_AT Trans-prenyltransferase, mRNA (cDNA clone MGC:28441 IMAGE:4039464) mm
YEAST_2:1773062_AT Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8299 isoprenoid biosynthesis inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB37678 Coenzyme q (ubiquinone) biosynthesis protein 1 [Caenorhabditis elegans] ref|NP_491588.1| COenzyme Q (ubiquinone) biosynthesis family member (coq-1) [Caenorhabditis elegans] 0.0
blast CAE66926 Hypothetical protein CBG12314 [Caenorhabditis briggsae] 0.0
blast AAB37678 Coenzyme q (ubiquinone) biosynthesis protein 1 [Caenorhabditis elegans] ref|NP_491588.1| COenzyme Q (ubiquinone) biosynthesis family member (coq-1) [Caenorhabditis elegans] 2.0E-83
blast XP_781598 PREDICTED: similar to trans-prenyltransferase [Strongylocentrotus purpuratus] 1.0E-74
blast CAE66926 Hypothetical protein CBG12314 [Caenorhabditis briggsae] 3.0E-71
blast NP_055132 trans-prenyltransferase [Homo sapiens] emb|CAI17280.1| trans-prenyltransferase (TPT) [Homo sapiens] 3.0E-15
Protein Domains
Database ID Description E-Value
Pfam IPR000092 EMBL-EBI Polyprenyl synthetase 5.0E-14
Pfam IPR000092 EMBL-EBI Polyprenyl synthetase 1.4E-54
Sequence
Target Sequence 
>C. ELEGANS:183541_AT
atgggtgttctaccgaaaatcaatattgtcgcaaggcagttcagaaaatgttcaatggca
gccacatcaacatctacatcctcatcagataatagtgttgcttcaacagctttcgtgcag
gaacatgttagacaaatgcagaacgatataatggtacaactaataccacaggatgaatcg
ggtgccgttgaaaatctagcagacttgaatgttacatcgaatttaggacgaatgacacat
tattattttcaacagggtggaaaaatgttacggccgactgtatcgcttcttatgggaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGGGTGTTCTACCGAAAATCAATA 62 51 13 Antisense
ATATTGTCGCAAGGCAGTTCAGAAA 527 17 35 Antisense
CAATGGCAGCCACATCAACATCTAC 355 525 65 Antisense
CATCAACATCTACATCCTCATCAGA 569 213 77 Antisense
CCTCATCAGATAATAGTGTTGCTTC 96 269 92 Antisense
GTTGCTTCAACAGCTTTCGTGCAGG 700 437 109 Antisense
GCTTTCGTGCAGGAACATGTTAGAC 35 305 121 Antisense
ACCACAGGATGAATCGGGTGCCGTT 357 85 177 Antisense
CTAGCAGACTTGAATGTTACATCGA 570 225 208 Antisense
AATGTTACGGCCGACTGTATCGCTT 548 161 276 Antisense
CCGACTGTATCGCTTCTTATGGGAA 488 263 286 Antisense
Sequence Source Affymetrix Proprietary Database