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[183460_s_at]

Description Y39B6B.F /REP_DB=WormBase Gene ID /WP=CE21679 /TR=Q9NEV3 /GB=CAB60911.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 46      6grp_high1_10_10 > 64      4grp_highest_8_8 > 23      4grp_high_8_8 > 05      6grp_highest_nonorm > 81      6grp_total > 55      4grp_total > 03      6grp_cgc > 56      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 521
1 2 3 4 range
A 307.2
(-2.5)
P 		276.4
(-2.8)
P 		261.9
(-3)
P 		773.1
(3)
P 		511
B 354.9
(-1.6)
P 		252.2
(-3)
P 		289.5
(-2.5)
P 		688.9
(3)
P 		437
C 292.8
(-2.9)
P 		291.6
(-2.9)
P 		283.1
(-3)
P 		771.5
(3)
P 		488
avr 318.3
(-2.4) 		273.4
(-3) 		278.2
(-2.9) 		744.5
(3) 		471

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 165
1 2 3 4 5 6 range
A 302.6
(-0.4)
P 		297
(-0.7)
P 		363.6
(3)
P 		281.6
(-1.5)
P 		254.9
(-3)
P 		344.5
(1.9)
P 		109
B 313.9
(-3)
P 		329.6
(-1.7)
P 		357.5
(0.6)
P 		387.4
(3)
P 		327.7
(-1.9)
P 		337.2
(-1.1)
P 		74
C 232.3
(-2.3)
P 		309.6
(3)
P 		289.7
(1.6)
P 		303.8
(2.6)
P 		222.7
(-3)
P 		304.2
(2.6)
P 		87
avr 282.9
(-1.7) 		312.1
(0.8) 		336.9
(3) 		324.3
(1.9) 		268.4
(-3) 		328.6
(2.3) 		69
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 87
1 2 3 4 range
A 111.9
(2.9)
P 		60
(-3)
P 		68.5
(-2)
P 		113.2
(3)
P 		53
B 113.2
(0.6)
P 		62.3
(-3)
P 		67.1
(-2.7)
P 		146.8
(3)
P 		85
C 96.9
(-1.3)
P 		83.8
(-3)
P 		98.7
(-1.1)
P 		130.1
(3)
P 		46
avr 107.3
(0.8) 		68.7
(-3) 		78.1
(-2.1) 		130
(3) 		61

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 55.8
(-3)
P 		105.6
(3)
P 		79.2
(-0.2)
P 		71.4
(-1.1)
P 		76.9
(-0.5)
P 		83.9
(0.4)
P 		50
B 109.2
(-0.1)
P 		109.7
(-0)
P 		86.8
(-3)
P 		102.6
(-1)
P 		133.2
(3)
P 		125.8
(2)
P 		46
C 86.1
(0.7)
P 		94.5
(1.9)
P 		73.7
(-1.1)
P 		61.1
(-3)
P 		72.1
(-1.4)
P 		101.8
(3)
P 		41
avr 83.7
(-1.7) 		103.3
(2.9) 		79.9
(-2.6) 		78.4
(-3) 		94.1
(0.7) 		103.8
(3) 		25
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 183460_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19436
Sequence Type Exemplar sequence
Representative Public ID Y39B6B.F NCBI
Target Description Y39B6B.F /REP_DB=WormBase Gene ID /WP=CE21679 /TR=Q9NEV3 /GB=CAB60911.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_171588(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_171588 NCBI Caenorhabditis elegans TWiK family of potassium channels family member (twk-46) (twk-46) mRNA, complete cds. 11/11 None
SNAP00000030544 ENSEMBL cdna:SNAP chromosome:CEL140:V:19062784:19069480:1 11/11 None
GENEFINDER00000030727 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:19062763:19071045:1 11/11 None
Y39B6A.19 ENSEMBL cdna:known chromosome:CEL140:V:19062753:19069480:1 gene:Y39B6A.19 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:19062762-19069480(+) 97.54 100.0
Public Domain and Genome References
Gene Title
Gene Symbol twk-46
Ensembl Y39B6A.19
Entrez Gene 180252 Entrez gene
SwissProt Q9NEV3 EMBL-EBI
WormBase CE29861 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CHICKEN:GGAAFFX.11853.1.S1_S_AT potassium channel, subfamily K, member 1 gga
CHICKEN:GGAAFFX.6963.1.S1_AT potassium channel, subfamily K, member 1 gga
CHICKEN:GGA.4356.1.S1_AT Potassium channel, subfamily K, member 1 gga
HG-U133_PLUS_2:204679_AT potassium channel, subfamily K, member 1 hs
HG-U133A_2:204679_AT potassium channel, subfamily K, member 1 hs
HG-U133A:204679_AT potassium channel, subfamily K, member 1 hs
HG-FOCUS:204679_AT potassium channel, subfamily K, member 1 hs
HG-U133_PLUS_2:204678_S_AT potassium channel, subfamily K, member 1 hs
HG-U133A_2:204678_S_AT potassium channel, subfamily K, member 1 hs
HG-U133A:204678_S_AT potassium channel, subfamily K, member 1 hs
HU35KSUBC:RC_Z39663_S_AT potassium channel, subfamily K, member 1 hs
HUGENEFL:U90065_S_AT potassium channel, subfamily K, member 1 hs
HUGENEFL:U33632_AT potassium channel, subfamily K, member 1 hs
U133_X3P:G4504846_3P_AT potassium channel, subfamily K, member 1 hs
U133_X3P:G1916294_3P_A_AT potassium channel, subfamily K, member 1 hs
HG-U95AV2:37552_AT potassium channel, subfamily K, member 1 hs
U133_X3P:HS2.376874.1.S1_3P_X_AT Potassium channel, subfamily K, member 1 hs
U133_X3P:1566465_3P_AT Potassium channel, subfamily K, member 1 hs
HG-U133_PLUS_2:1566465_AT Potassium channel, subfamily K, member 1 hs
HG-U133_PLUS_2:1566464_AT Potassium channel, subfamily K, member 1 hs
HG-U95D:89390_R_AT Potassium channel, subfamily K, member 1 hs
MG-U74AV2:102335_AT potassium channel, subfamily K, member 1 mm
MOE430A:1455896_A_AT potassium channel, subfamily K, member 1 mm
MOUSE430A_2:1455896_A_AT potassium channel, subfamily K, member 1 mm
MOUSE430_2:1455896_A_AT potassium channel, subfamily K, member 1 mm
MOE430A:1448690_AT potassium channel, subfamily K, member 1 mm
MOUSE430A_2:1448690_AT potassium channel, subfamily K, member 1 mm
MOUSE430_2:1448690_AT potassium channel, subfamily K, member 1 mm
MU19KSUBB:TC30352_AT Potassium channel, subfamily K, member 1, mRNA (cDNA clone MGC:5789 IMAGE:3592756) mm
RN-U34:AF022819_AT potassium channel, subfamily K, member 1 rn
RG-U34A:AF022819_AT potassium channel, subfamily K, member 1 rn
RG-U34B:RC_AA926247_AT potassium channel, subfamily K, member 1 rn
RAE230A:1369500_AT potassium channel, subfamily K, member 1 rn
RAT230_2:1369500_AT potassium channel, subfamily K, member 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6811 ion transport inferred from electronic annotation QuickGO AmiGO
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5216 ion channel activity inferred from electronic annotation QuickGO AmiGO
5267 potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast T45032 hypothetical protein Y39B6B.f [imported] - Caenorhabditis elegans 0.0
blast CAD31817 Hypothetical protein Y39B6A.19 [Caenorhabditis elegans] ref|NP_741678.1| TWiK family of potassium channels family member (twk-46) [Caenorhabditis elegans] 1.0E-176
blast CAD31817 Hypothetical protein Y39B6A.19 [Caenorhabditis elegans] ref|NP_741678.1| TWiK family of potassium channels family member (twk-46) [Caenorhabditis elegans] 1.0E-172
blast CAE72984 Hypothetical protein CBG20326 [Caenorhabditis briggsae] 1.0E-164
blast CAE72984 Hypothetical protein CBG20326 [Caenorhabditis briggsae] 1.0E-160
blast T45032 hypothetical protein Y39B6B.f [imported] - Caenorhabditis elegans 1.0E-150
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_741678.1 6 27-46,108-126,138-160,188-210,217-236,251-273
Y39B6A.19 6 27-46,108-126,138-160,188-210,217-236,251-273
SNAP00000030544 6 20-39,101-119,131-153,181-203,210-229,244-266
GENEFINDER00000030727 5 24-46,211-233,261-283,290-309,324-346
Sequence
Target Sequence 
>C. ELEGANS:183460_S_AT
cttcttcgccggtacacttattagtaccgtagggtacggaagagtcagcccgcgaacaga
atatggaaaactttttactattttgtattgtgttataggaatcccactcaccttggcatt
gctatcggcaattgtcgctagaatgagagaaccatcgcataagctcaggggactgttaaa
tcaacgattaggacacttattcactgttaatcatattcagctaatccacgtgggcgtcgt
gttcgcatctctcctcctcttcgtcttcgccattccggcgtgggtattttcatcgatcga
aacggattggtcatatctagatgcgttctactactgctttgtatcacttaccacaatcgg
attgggagatttcgagccgggagatgatccgaatcaatcgttccgtggattatacaagat
tggagctactgtatacctgatgggcggtctgtgttgtatgatgttgttcctggcgacact
ctacgacattccgcaattcaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTTCTTCGCCGGTACACTTATTAGT 129 221 573 Antisense
GGTACGGAAGAGTCAGCCCGCGAAC 303 505 605 Antisense
GTGTTATAGGAATCCCACTCACCTT 230 483 662 Antisense
CTCACCTTGGCATTGCTATCGGCAA 282 227 679 Antisense
GAACCATCGCATAAGCTCAGGGGAC 671 345 721 Antisense
TAATCCACGTGGGCGTCGTGTTCGC 357 635 794 Antisense
TCCGGCGTGGGTATTTTCATCGATC 547 593 846 Antisense
GCGTTCTACTACTGCTTTGTATCAC 503 291 895 Antisense
TGATCCGAATCAATCGTTCCGTGGA 447 565 957 Antisense
TATGATGTTGTTCCTGGCGACACTC 705 655 1029 Antisense
ACTCTACGACATTCCGCAATTCAAT 236 101 1050 Antisense
Sequence Source Affymetrix Proprietary Database