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[183365_at]

Description C48E7.9 /REP_DB=WormBase Gene ID /WP=CE08824 /TR=O02084 /GB=AAK21362.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation
Cluster 6grp_total > 28      4grp_total > 12      6grp_cgc > 04      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 61
1 2 3 4 range
A 31.2
(-2)
P 		31.5
(-2)
A 		24.4
(-3)
A 		66.5
(3)
A 		42
B 5.8
(-3)
A 		29.9
(2.6)
A 		20.3
(0.3)
A 		31.8
(3)
A 		26
C 43.1
(3)
A 		7.3
(-3)
A 		15.6
(-1.6)
A 		20.3
(-0.8)
A 		36
avr 26.7
(-1) 		22.9
(-2.1) 		20.1
(-3) 		39.5
(3) 		19

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 55
1 2 3 4 5 6 range
A 56
(3)
A 		45.6
(1.9)
A 		23.7
(-0.5)
A 		1.1
(-3)
A 		18.6
(-1.1)
A 		31.9
(0.4)
A 		55
B 7.2
(-2.9)
A 		22.7
(0.7)
A 		6.6
(-3)
A 		13.6
(-1.4)
A 		32.8
(3)
A 		26.3
(1.5)
A 		26
C 39.4
(3)
A 		25.7
(0.2)
A 		9.9
(-3)
A 		37.3
(2.6)
A 		21.3
(-0.7)
A 		12.5
(-2.5)
A 		30
avr 34.2
(3) 		31.3
(2.2) 		13.4
(-3) 		17.3
(-1.9) 		24.2
(0.1) 		23.6
(-0.1) 		21
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 11.4
(3)
P 		6.8
(-2.5)
A 		6.4
(-3)
A 		9.7
(1)
A 		5
B 1.8
(-3)
A 		7.4
(3)
A 		4.7
(0.1)
A 		6.8
(2.4)
A 		6
C 14.3
(3)
A 		2.1
(-3)
A 		5.4
(-1.4)
A 		3.4
(-2.4)
A 		12
avr 9.2
(3) 		5.4
(-3) 		5.5
(-2.8) 		6.6
(-1.1) 		4

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 10.3
(0.8)
A 		16.2
(3)
A 		5.2
(-1.2)
A 		0.3
(-3)
A 		5.6
(-1)
A 		7.8
(-0.2)
A 		16
B 2.5
(-2.5)
A 		7.6
(0.1)
A 		1.6
(-3)
A 		3.6
(-2)
A 		13.3
(3)
A 		9.8
(1.2)
A 		12
C 14.6
(3)
A 		7.8
(-0.4)
A 		2.5
(-3)
A 		7.5
(-0.5)
A 		6.9
(-0.8)
A 		4.2
(-2.2)
A 		12
avr 9.1
(1.9) 		10.5
(3) 		3.1
(-3) 		3.8
(-2.4) 		8.6
(1.5) 		7.3
(0.4) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 183365_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1733
Sequence Type Exemplar sequence
Representative Public ID C48E7.9 NCBI
Target Description C48E7.9 /REP_DB=WormBase Gene ID /WP=CE08824 /TR=O02084 /GB=AAK21362.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059409(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059409 NCBI Caenorhabditis elegans TWiK family of potassium channels family member (twk-37) (twk-37) mRNA, complete cds. 11/11 None
SNAP00000002347 ENSEMBL cdna:SNAP chromosome:CEL140:I:6277696:6279183:-1 11/11 None
GENEFINDER00000002350 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:6277696:6279645:-1 11/11 None
C48E7.9 ENSEMBL cdna:known chromosome:CEL140:I:6277696:6279183:-1 gene:C48E7.9 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:6277624-6279112(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol twk-37
Ensembl C48E7.9
Entrez Gene 183583 Entrez gene
SwissProt Q8IG65 EMBL-EBI
WormBase CE08824 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5267 potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAN60530 Twik family of potassium channels protein 37 [Caenorhabditis elegans] ref|NP_491810.1| TWiK family of potassium channels family member (twk-37) [Caenorhabditis elegans] 0.0
blast CAE67155 Hypothetical protein CBG12580 [Caenorhabditis briggsae] 1.0E-113
blast CAE67155 Hypothetical protein CBG12580 [Caenorhabditis briggsae] 1.0E-112
blast CAA93875 Hypothetical protein T01B4.1 [Caenorhabditis elegans] ref|NP_510654.1| TWiK family of potassium channels family member (twk-21) [Caenorhabditis elegans] 1.0E-20
Protein Domains
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_491810.1 4 61-83,172-194,229-251,282-304
C48E7.9 4 61-83,172-194,229-251,282-304
SNAP00000002347 4 61-83,172-194,229-251,282-304
GENEFINDER00000002350 4 93-115,204-226,261-283,314-336
Sequence
Target Sequence 
>C. ELEGANS:183365_AT
agagtttctggatgggctggcttatgtaatcacttgtattacgacaatagggtacggcga
acttgtctgtcacacaattgccggtaaattggttactgtagcttatggtattataggaat
tgctctaacactctacgtacttcgcaacaatggaaaaataacgttgaaaatatgcaattt
gacactcaaaatttttgcaatttgcgttcgaaaatgtggcaaaaagtcggcaaagtataa
gatgacagtactgaaagcttttattcttcttgtcacattttggggcttcggagcacttgc
aattgctgtctatgaggagtttgtattctatgatgccttgtacttttctttcagtacatt
ttcaactattggatttggagattttgttccgtcaggtcatatctctggaactattatttg
tgtattacactttatcgatttatcactgatttcaatggttttagttctcgttcatcattc
gatggaaaacagatttatgagagttttggagctcttcgatgaacggcatgctaccgacac
tttagaaacaaatatgatatcacctggtgcttctcaacgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGAGTTTCTGGATGGGCTGGCTTAT 413 69 453 Antisense
TAGGGTACGGCGAACTTGTCTGTCA 479 651 500 Antisense
AATTGCTCTAACACTCTACGTACTT 238 179 570 Antisense
AGCTTTTATTCTTCTTGTCACATTT 450 79 708 Antisense
GTCACATTTTGGGGCTTCGGAGCAC 683 463 724 Antisense
TGATGCCTTGTACTTTTCTTTCAGT 145 567 783 Antisense
TGTTCCGTCAGGTCATATCTCTGGA 322 563 837 Antisense
TGGTTTTAGTTCTCGTTCATCATTC 465 551 908 Antisense
TGGAGCTCTTCGATGAACGGCATGC 688 547 959 Antisense
GAACGGCATGCTACCGACACTTTAG 609 347 973 Antisense
GATATCACCTGGTGCTTCTCAACGG 299 425 1008 Antisense
Sequence Source Affymetrix Proprietary Database