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[183198_at] tyrosine-protein kinase

Description C48C5.2 /REP_DB=WormBase Gene ID /WP=CE04225 /TR=Q18699 /GB=AAB37018.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 10      6grp_high1_10_10 > 0      4grp_highest_8_8 > 54      4grp_high_8_8 > 10      6grp_highest_nonorm > 90      6grp_total > 14      4grp_total > 22      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 142
1 2 3 4 range
A 182.6
(2.1)
P 		62.5
(-3)
P 		74.9
(-2.5)
P 		204.6
(3)
P 		142
B 143.7
(3)
P 		108.4
(0)
P 		72.4
(-3)
P 		129
(1.8)
P 		71
C 201.9
(3)
P 		111.3
(-1.1)
P 		69.5
(-3)
P 		178.7
(1.9)
P 		132
avr 176.1
(3) 		94.1
(-1.7) 		72.3
(-3) 		170.8
(2.7) 		104

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 109
1 2 3 4 5 6 range
A 100.6
(-0.1)
P 		97
(-0.6)
P 		78.9
(-3)
P 		123.3
(3)
P 		105
(0.5)
P 		88.5
(-1.7)
P 		44
B 135.6
(3)
P 		127.2
(1.6)
P 		124.2
(1.2)
P 		135.6
(3)
P 		102.9
(-2.3)
P 		98.4
(-3)
P 		37
C 181.4
(3)
P 		145.4
(1)
P 		119.2
(-0.4)
P 		117.6
(-0.5)
P 		78.5
(-2.6)
P 		72
(-3)
P 		109
avr 139.2
(3) 		123.2
(1.2) 		107.4
(-0.6) 		125.5
(1.4) 		95.5
(-2) 		86.3
(-3) 		53
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 53
1 2 3 4 range
A 66.5
(3)
P 		13.6
(-3)
P 		19.6
(-2.3)
P 		30
(-1.1)
P 		53
B 45.8
(3)
P 		26.8
(-0.9)
P 		16.8
(-3)
P 		27.5
(-0.8)
P 		29
C 66.8
(3)
P 		32
(-1.9)
P 		24.2
(-3)
P 		30.1
(-2.2)
P 		43
avr 59.7
(3) 		24.1
(-2.4) 		20.2
(-3) 		29.2
(-1.6) 		40

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 50
1 2 3 4 5 6 range
A 18.5
(-2.5)
P 		34.5
(3)
P 		17.2
(-3)
P 		31.3
(1.9)
P 		31.7
(2)
P 		21.5
(-1.5)
P 		17
B 47.2
(3)
P 		42.4
(1.3)
P 		30.2
(-3)
P 		35.9
(-1)
P 		41.8
(1.1)
P 		36.7
(-0.7)
P 		17
C 67.2
(3)
P 		44.4
(-0.1)
P 		30.3
(-2.1)
P 		23.7
(-3)
P 		25.4
(-2.8)
P 		24.1
(-2.9)
P 		44
avr 44.3
(3) 		40.4
(1.7) 		25.9
(-3) 		30.3
(-1.6) 		33
(-0.7) 		27.4
(-2.5) 		18
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 183198_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16570
Sequence Type Exemplar sequence
Representative Public ID C48C5.2 NCBI
Target Description C48C5.2 /REP_DB=WormBase Gene ID /WP=CE04225 /TR=Q18699 /GB=AAB37018.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077111(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077111 NCBI Caenorhabditis elegans D1073.1 (D1073.1) mRNA, complete cds. 11/11 A 
GENEFINDER00000028945 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:8944403:8950431:-1 10/11 None
D1073.1 ENSEMBL cdna:known chromosome:CEL140:X:8942325:8948799:-1 gene:D1073.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000028940 2/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:8944798-8948798(-) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase
Ensembl D1073.1
Entrez Gene 183575 Entrez gene
SwissProt Q94183 EMBL-EBI
WormBase CE34285 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
30001 metal ion transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
46872 metal ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB09104 Hypothetical protein D1073.1 [Caenorhabditis elegans] ref|NP_509512.3| D1073.1 [Caenorhabditis elegans] 0.0
blast AAB09104 Hypothetical protein D1073.1 [Caenorhabditis elegans] ref|NP_509512.3| D1073.1 [Caenorhabditis elegans] 1.0E-158
blast T15814 hypothetical protein C48C5.2 - Caenorhabditis elegans 1.0E-129
blast CAE57317 Hypothetical protein CBG00240 [Caenorhabditis briggsae] 1.0E-124
blast CAE57317 Hypothetical protein CBG00240 [Caenorhabditis briggsae] 1.0E-113
blast T15814 hypothetical protein C48C5.2 - Caenorhabditis elegans 1.0E-113
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 3.4E-23
Pfam IPR000719 EMBL-EBI Protein kinase 3.1E-8
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509512.3 1 211-230
D1073.1 1 211-230
GENEFINDER00000028945 1 235-257
Sequence
Target Sequence 
>C. ELEGANS:183198_AT
agtgctggcattgtttggattttcttgttggaaaaattgagcttcgtgcgaattatcccg
tcaaagttgcatttgttgataagacacgtctcgatacggatttcttggttgtcaccggat
atcccatcgacaatatctctatggcaattacaaaaatgcagagcaactacagtgaaacaa
actttgttggacgtgaaaaagacgcgattttcttctcgagtctagttgtgcgaatggaaa
aacgcccactcttctatcaaaaaacatatcgagtattcacaaaggacgctgcagaaggtg
atcatttgtctggagatttgaggtttgaagtctgtacaaatggaagctgtgatgcaattg
aaaagcacgtctcacatttgggtctaattaatggaactattgacgacttcataatcgtgg
aatacccttacaaacaagaaattcaaatagttgtttttctgattgttatttgcctgctga
ttgtggtatctgcattagcgttctaccacaggttga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGTGCTGGCATTGTTTGGATTTTCT 537 57 197 Antisense
GCTTCGTGCGAATTATCCCGTCAAA 26 307 237 Antisense
GACACGTCTCGATACGGATTTCTTG 41 367 279 Antisense
TCTTGGTTGTCACCGGATATCCCAT 378 617 299 Antisense
ATATCCCATCGACAATATCTCTATG 431 21 315 Antisense
ACGCGATTTTCTTCTCGAGTCTAGT 299 91 398 Antisense
CGCCCACTCTTCTATCAAAAAACAT 55 257 439 Antisense
AAGCACGTCTCACATTTGGGTCTAA 632 149 559 Antisense
GTTTTTCTGATTGTTATTTGCCTGC 375 447 649 Antisense
TTTGCCTGCTGATTGTGGTATCTGC 221 669 665 Antisense
GCATTAGCGTTCTACCACAGGTTGA 482 307 688 Antisense
Sequence Source Affymetrix Proprietary Database