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[182202_at]

Description M01D7.6 /REP_DB=WormBase Gene ID /WP=CE12270 /TR=O01971 /GB=AAB58065.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 87      6grp_high1_10_10 > 78      4grp_highest_8_8 > 02      4grp_high_8_8 > 46      6grp_highest_nonorm > 95      6grp_total > 68      4grp_total > 49      6grp_highest_sub > Da      6grp_cgc > 49      6grp_high1_sub > Cu      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 580
1 2 3 4 range
A 432.3
(-3)
P 		1011.9
(3)
P 		837.8
(1.2)
P 		696.9
(-0.3)
P 		580
B 548.5
(-3)
P 		696
(3)
P 		666.9
(1.8)
P 		550.8
(-2.9)
P 		148
C 742.7
(-0.2)
P 		809.8
(1)
P 		914.5
(3)
P 		592.7
(-3)
P 		322
avr 574.5
(-3) 		839.2
(3) 		806.4
(2.3) 		613.5
(-2.1) 		265

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 853
1 2 3 4 5 6 range
A 604
(-2.1)
P 		469.2
(-3)
P 		532.5
(-2.6)
P 		573.3
(-2.3)
P 		723.9
(-1.2)
P 		1322.3
(3)
P 		853
B 592.1
(-2.5)
P 		575.8
(-2.7)
P 		618.2
(-2.2)
P 		740
(-0.6)
P 		554.5
(-3)
P 		1011.2
(3)
P 		457
C 816
(1.4)
P 		708.3
(-0)
P 		608.1
(-1.4)
P 		486.8
(-3)
P 		902.5
(2.5)
P 		936.6
(3)
P 		450
avr 670.7
(-2) 		584.4
(-3) 		586.3
(-3) 		600
(-2.8) 		727
(-1.3) 		1090
(3) 		506
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 219
1 2 3 4 range
A 157.4
(-0.2)
P 		219.7
(3)
P 		219
(3)
P 		102
(-3)
P 		118
B 174.9
(3)
P 		171.9
(2.7)
P 		154.5
(0.9)
P 		117.4
(-3)
P 		58
C 245.9
(1)
P 		232.8
(0.6)
P 		318.7
(3)
P 		99.9
(-3)
P 		219
avr 192.7
(1.2) 		208.1
(1.9) 		230.7
(3) 		106.4
(-3) 		124

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 279
1 2 3 4 5 6 range
A 111.3
(-3)
P 		166.9
(-1.4)
P 		116
(-2.9)
P 		145.4
(-2)
P 		218.4
(0.1)
P 		321.9
(3)
P 		211
B 206
(-1.5)
P 		191.7
(-1.9)
P 		150.1
(-3)
P 		196
(-1.8)
P 		225.3
(-1)
P 		377.1
(3)
P 		227
C 302.5
(2.7)
P 		216.1
(0.3)
P 		154.8
(-1.4)
P 		97.9
(-3)
P 		292
(2.4)
P 		313.5
(3)
P 		216
avr 206.6
(-1) 		191.6
(-1.4) 		140.3
(-3) 		146.4
(-2.8) 		245.2
(0.2) 		337.5
(3) 		197
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 182202_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.236
Sequence Type Exemplar sequence
Representative Public ID M01D7.6 NCBI
Target Description M01D7.6 /REP_DB=WormBase Gene ID /WP=CE12270 /TR=O01971 /GB=AAB58065.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058506(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058506 NCBI Caenorhabditis elegans human EMeRin homolog family member (emr-1) (emr-1) mRNA, complete cds. 11/11 A 
SNAP00000009588 ENSEMBL cdna:SNAP chromosome:CEL140:I:1842461:1843087:1 11/11 None
GENEFINDER00000009606 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:1842461:1843126:1 11/11 None
M01D7.6.1 ENSEMBL cdna:known chromosome:CEL140:I:1842444:1843210:1 gene:M01D7.6 11/11 A 
M01D7.6.2 ENSEMBL cdna:known chromosome:CEL140:I:1842444:1843157:1 gene:M01D7.6 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:1842460-1843087(+) 98.6 100.0
Public Domain and Genome References
Gene Title
Gene Symbol emr-1
Ensembl M01D7.6
Entrez Gene 171752 Entrez gene
SwissProt O01971 EMBL-EBI
WormBase CE12270 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
5635 nuclear membrane inferred from electronic annotation QuickGO AmiGO
5639 integral to nuclear inner membrane inferred from direct assay QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAB58065 Human emerin homolog protein 1 [Caenorhabditis elegans] ref|NP_490907.1| human EMeRin homolog family member (emr-1) [Caenorhabditis elegans] sp|O01971|EMR1_CAEEL Emerin homolog 1 (Ce-emerin) 4.0E-62
blast AAB58065 Human emerin homolog protein 1 [Caenorhabditis elegans] ref|NP_490907.1| human EMeRin homolog family member (emr-1) [Caenorhabditis elegans] sp|O01971|EMR1_CAEEL Emerin homolog 1 (Ce-emerin) 1.0E-61
blast CAE74464 Hypothetical protein CBG22210 [Caenorhabditis briggsae] 4.0E-16
blast CAE74464 Hypothetical protein CBG22210 [Caenorhabditis briggsae] 5.0E-16
Protein Domains
Database ID Description E-Value
scop a.140.1.LEM domain All alpha proteins; LEM/SAP HeH motif; LEM domain; LEM domain 9.99999993922529E-9
Pfam IPR003887 EMBL-EBI Lamino-associated polypeptide 2/emerin 8.6E-25
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_490907.1 1 126-148
M01D7.6.1 1 126-148
M01D7.6.2 1 126-148
SNAP00000009588 1 126-148
GENEFINDER00000009606 1 126-148
Sequence
Target Sequence 
>C. ELEGANS:182202_AT
tctcccagctgacagatgccgaactacgcgatagccttaaaagccacggggtttctgttg
ggccaattgtggcgacgacccgcaagctctacgagaagaagcttatcaagttatcagacg
gaagcattaacaatcaatcaaatctcaacgactctcaattcaacgaggattcattgatca
tcagctcgtcaccgaagaaatcaccgccacaacgagttttccagaacgtgtcagctgcaa
cagcggcagctactacctctcccgaatcggacagcgacgattgcgaggagtc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCTCCCAGCTGACAGATGCCGAACT 496 611 20 Antisense
TGCCGAACTACGCGATAGCCTTAAA 294 585 36 Antisense
GTTGGGCCAATTGTGGCGACGACCC 252 435 76 Antisense
CGACCCGCAAGCTCTACGAGAAGAA 590 245 95 Antisense
AATCTCAACGACTCTCAATTCAACG 683 169 160 Antisense
TGATCATCAGCTCGTCACCGAAGAA 229 563 194 Antisense
GAAATCACCGCCACAACGAGTTTTC 60 361 216 Antisense
GAGTTTTCCAGAACGTGTCAGCTGC 175 399 233 Antisense
CTGCAACAGCGGCAGCTACTACCTC 447 237 254 Antisense
TACCTCTCCCGAATCGGACAGCGAC 637 649 273 Antisense
CGGACAGCGACGATTGCGAGGAGTC 12 241 287 Antisense
Sequence Source Affymetrix Proprietary Database