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[182134_s_at] --- /// G-protein coupled receptor, srh family

Description F08E10.6 /REP_DB=WormBase Gene ID /WP=CE18576 /TR=Q9XXN9 /GB=CAA16505.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_total > 23      4grp_total > 27      6grp_cgc > 20      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 51
1 2 3 4 range
A 16.3
(-2.7)
A 		54.2
(3)
A 		14.6
(-3)
A 		48.1
(2.1)
A 		40
B 23
(-0)
A 		11.1
(-2.6)
A 		9.5
(-3)
A 		36.7
(3)
A 		27
C 4.9
(-2.8)
A 		21
(-0.4)
A 		3.4
(-3)
A 		44.6
(3)
A 		41
avr 14.7
(-2) 		28.8
(0.5) 		9.2
(-3) 		43.1
(3) 		34

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 34
1 2 3 4 5 6 range
A 31.1
(2.3)
A 		2.9
(-2.7)
A 		29.7
(2.1)
A 		34.8
(3)
A 		1.1
(-3)
A 		4.9
(-2.3)
A 		34
B 2.1
(-3)
A 		6.1
(1.3)
A 		2.4
(-2.7)
A 		7.7
(3)
A 		6.1
(1.3)
A 		5.5
(0.6)
A 		6
C 19.8
(1.5)
A 		26
(3)
A 		3.3
(-2.5)
A 		2.9
(-2.6)
A 		1.2
(-3)
A 		2.7
(-2.6)
A 		25
avr 17.7
(3) 		11.7
(0.6) 		11.8
(0.6) 		15.1
(2) 		2.8
(-3) 		4.4
(-2.4) 		15
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 6
(-1.4)
A 		11.8
(3)
A 		3.8
(-3)
A 		7
(-0.6)
A 		8
B 7.3
(2.5)
A 		2.7
(-2.5)
A 		2.2
(-3)
A 		7.8
(3)
A 		6
C 1.6
(-2.6)
A 		6
(1.6)
A 		1.2
(-3)
A 		7.5
(3)
A 		6
avr 5
(0.1) 		6.8
(2.3) 		2.4
(-3) 		7.4
(3) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 9
1 2 3 4 5 6 range
A 5.7
(0.8)
A 		1
(-2.5)
A 		6.5
(1.4)
A 		8.8
(3)
A 		0.3
(-3)
A 		1.2
(-2.4)
A 		9
B 0.7
(-2.7)
A 		2
(1.4)
A 		0.6
(-3)
A 		2
(1.4)
A 		2.5
(3)
A 		2
(1.4)
A 		2
C 7.3
(2.5)
A 		7.9
(3)
A 		0.8
(-2.7)
A 		0.6
(-2.8)
A 		0.4
(-3)
A 		0.9
(-2.6)
A 		8
avr 4.6
(3) 		3.6
(1.3) 		2.6
(-0.4) 		3.8
(1.6) 		1.1
(-3) 		1.4
(-2.5) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 182134_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12796
Sequence Type Exemplar sequence
Representative Public ID F08E10.6 NCBI
Target Description F08E10.6 /REP_DB=WormBase Gene ID /WP=CE18576 /TR=Q9XXN9 /GB=CAA16505.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075027(11), NM_074962(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075027 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-111) (srh-111) mRNA, complete cds. 11/11 A 
NM_074962 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-112) (srh-112) mRNA, complete cds. 11/11 A 
SNAP00000010312 ENSEMBL cdna:SNAP chromosome:CEL140:V:17227663:17228796:-1 11/11 None
GENEFINDER00000010320 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:17227663:17228520:-1 11/11 None
SNAP00000039054 ENSEMBL cdna:SNAP chromosome:CEL140:V:17486621:17487478:-1 11/11 None
GENEFINDER00000039056 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:17484279:17487478:-1 11/11 None
T19C9.2 ENSEMBL cdna:known chromosome:CEL140:V:17227663:17228796:-1 gene:T19C9.2 11/11 A 
F08E10.6 ENSEMBL cdna:known chromosome:CEL140:V:17486621:17487754:-1 gene:F08E10.6 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:17486620-17487754(-) 100.0 100.0
chrV:17227624-17481962(-) 92.58 92.58
Public Domain and Genome References
Gene Title
G-protein coupled receptor, srh family
Gene Symbol srh-111
srh-112
Ensembl T19C9.2
F08E10.6
Entrez Gene 184187 Entrez gene
188597 Entrez gene
SwissProt Q9XXN9 EMBL-EBI
O45793 EMBL-EBI
WormBase CE18576 Wormbase
CE16419 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA16505 Hypothetical protein F08E10.6 [Caenorhabditis elegans] ref|NP_507428.1| Serpentine Receptor, class H family member (srh-111) [Caenorhabditis elegans] 0.0
blast CAB07487 Hypothetical protein T19C9.2 [Caenorhabditis elegans] ref|NP_507363.1| Serpentine Receptor, class H family member (srh-112) [Caenorhabditis elegans] 0.0
blast CAA16505 Hypothetical protein F08E10.6 [Caenorhabditis elegans] ref|NP_507428.1| Serpentine Receptor, class H family member (srh-111) [Caenorhabditis elegans] 1.0E-177
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 4.4E-100
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 4.3E-103
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.7E-35
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_507428.1 7 31-53,66-88,108-130,151-173,193-215,252-274,289-311
NP_507363.1 7 31-53,66-88,108-130,151-173,193-215,252-274,289-311
T19C9.2 7 31-53,66-88,108-130,151-173,193-215,252-274,289-311
F08E10.6 7 31-53,66-88,108-130,151-173,193-215,252-274,289-311
SNAP00000010312 7 31-53,66-88,108-130,151-173,193-215,252-274,289-311
GENEFINDER00000010320 5 15-37,58-80,122-144,160-182,197-219
SNAP00000039054 5 15-37,58-80,122-144,160-182,197-219
GENEFINDER00000039056 7 15-37,57-79,101-123,130-147,167-189,196-218,254-276
Sequence
Target Sequence 
>C. ELEGANS:182134_S_AT
ctggaaaattacgggctctagctatttacccttgccctacacgagagtttttcatattcc
ctgtttgtgtattcgagggcacgacgagccacatttttctcgtttatgccttggttatgt
cacatacatctggaaacattatatttcatgtcgcatgtctcgtatactacctttatattg
cgccaccacgcacactatctcaaaatactcgaagagatcagaaaatattcttagtctgcg
tgacggcacagacttcggtaccacttttggttataatcgctccggccatgatcgttttgt
tagcatcgtgggctggatattatcgtcaagaatggatgagtttggctgcaatttgtgttg
caactcacgggctcgccgagagcattgcgatcatgatggtgcacaaaccctatcgagcag
cgattaggaaaatgctccga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTGGAAAATTACGGGCTCTAGCTAT 317 241 542 Antisense
GGGCTCTAGCTATTTACCCTTGCCC 157 493 554 Antisense
TTGCCCTACACGAGAGTTTTTCATA 64 703 573 Antisense
CCTGTTTGTGTATTCGAGGGCACGA 544 263 601 Antisense
GAGGGCACGACGAGCCACATTTTTC 3 401 616 Antisense
GTTTATGCCTTGGTTATGTCACATA 614 449 643 Antisense
GTCACATACATCTGGAAACATTATA 485 465 660 Antisense
GTCTGCGTGACGGCACAGACTTCGG 9 469 775 Antisense
CACTTTTGGTTATAATCGCTCCGGC 344 197 803 Antisense
GTTTGGCTGCAATTTGTGTTGCAAC 416 451 881 Antisense
AGCAGCGATTAGGAAAATGCTCCGA 30 77 957 Antisense
Sequence Source Affymetrix Proprietary Database