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[182059_s_at]

Description Y40B1B.6 /REP_DB=WormBase Gene ID /WP=CE20240 /TR=Q9XWP6 /GB=CAA21604.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation
Cluster 6grp_high1_10_10 > 47      4grp_high_8_8 > 41      6grp_total > 47      4grp_total > 53      6grp_cgc > 18      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 140
1 2 3 4 range
A 186
(3)
P 		126.3
(0.4)
P 		105.4
(-0.5)
P 		46.2
(-3)
A 		140
B 158.8
(3)
P 		106.1
(-0.4)
P 		130.6
(1.2)
P 		66.7
(-3)
A 		92
C 171.7
(3)
P 		170.4
(2.9)
P 		121.9
(-1.4)
P 		103.7
(-3)
P 		68
avr 172.2
(3) 		134.3
(0.7) 		119.3
(-0.2) 		72.2
(-3) 		100

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 118
1 2 3 4 5 6 range
A 104
(-0.3)
P 		163
(2.8)
P 		52.9
(-3)
A 		115.2
(0.3)
P 		89.1
(-1.1)
P 		166.3
(3)
P 		113
B 142.6
(3)
P 		137.2
(2.3)
P 		94.8
(-3)
P 		110.3
(-1.1)
P 		99.6
(-2.4)
P 		132.3
(1.7)
P 		48
C 170.8
(3)
P 		108
(-1.5)
P 		129
(-0)
P 		87.9
(-3)
P 		129.7
(0)
P 		162.2
(2.4)
P 		83
avr 139.1
(1.6) 		136.1
(1.3) 		92.2
(-3) 		104.5
(-1.8) 		106.1
(-1.6) 		153.6
(3) 		61
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 61
1 2 3 4 range
A 67.7
(3)
P 		27.4
(-1)
P 		27.6
(-1)
P 		6.8
(-3)
A 		61
B 50.6
(3)
P 		26.2
(-1)
P 		30.3
(-0.3)
P 		14.2
(-3)
A 		36
C 56.8
(3)
P 		49
(1.8)
P 		42.5
(0.8)
P 		17.5
(-3)
P 		39
avr 58.4
(3) 		34.2
(-0.2) 		33.5
(-0.3) 		12.8
(-3) 		46

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 52
1 2 3 4 5 6 range
A 19.2
(-2)
P 		58
(3)
P 		11.5
(-3)
A 		29.2
(-0.7)
P 		26.9
(-1)
P 		40.5
(0.7)
P 		47
B 49.6
(3)
P 		45.7
(2.1)
P 		23
(-3)
P 		29.2
(-1.6)
P 		40.5
(0.9)
P 		49.4
(3)
P 		27
C 63.3
(3)
P 		32.9
(-1)
P 		32.8
(-1)
P 		17.7
(-3)
P 		42
(0.2)
P 		54.3
(1.8)
P 		46
avr 44
(2) 		45.5
(2.4) 		22.4
(-3) 		25.4
(-2.3) 		36.5
(0.3) 		48.1
(3) 		26
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 182059_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.803
Sequence Type Exemplar sequence
Representative Public ID Y40B1B.6 NCBI
Target Description Y40B1B.6 /REP_DB=WormBase Gene ID /WP=CE20240 /TR=Q9XWP6 /GB=CAA21604.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060965(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060965 NCBI Caenorhabditis elegans Suppressor of PResenilin defect family member (spr-5) (spr-5) mRNA, complete cds. 11/11 None
SNAP00000004547 ENSEMBL cdna:SNAP chromosome:CEL140:I:13446187:13458040:1 11/11 None
GENEFINDER00000004554 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:13446187:13458049:1 11/11 None
Y40B1B.6.1 ENSEMBL cdna:known chromosome:CEL140:I:13446176:13458316:1 gene:Y40B1B.6 11/11 None
Y40B1B.6.2 ENSEMBL cdna:known chromosome:CEL140:I:13446185:13458316:1 gene:Y40B1B.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:13446117-13457980(+) 98.75 100.0
Public Domain and Genome References
Gene Title
Gene Symbol spr-5
Ensembl Y40B1B.6
Entrez Gene 173214 Entrez gene
SwissProt Q9XWP6 EMBL-EBI
WormBase CE20240 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:256768_AT amine oxidase family protein / SWIRM domain-containing protein at
CANINE:1604735_AT similar to amine oxidase (flavin containing) domain 2 isoform a cfa
CANINE:1591849_AT similar to amine oxidase (flavin containing) domain 2 isoform a cfa
CANINE_2:CFA.229.1.S1_AT similar to amine oxidase (flavin containing) domain 2 isoform a cfa
CANINE_2:CFAAFFX.20684.1.S1_S_AT similar to amine oxidase (flavin containing) domain 2 isoform a cfa
DROSOPHILA_2:1634524_S_AT dm
DROSGENOME1:155096_AT dm
CHICKEN:GGAAFFX.20329.1.S1_S_AT similar to AOF2 protein gga
CHICKEN:GGAAFFX.22296.1.S1_S_AT similar to AOF2 protein gga
HU35KSUBA:H47839_AT amine oxidase (flavin containing) domain 2 hs
HU35KSUBA:W39183_S_AT amine oxidase (flavin containing) domain 2 hs
HU35KSUBC:RC_H56559_S_AT amine oxidase (flavin containing) domain 2 hs
HU35KSUBD:RC_AA193381_AT amine oxidase (flavin containing) domain 2 hs
U133_X3P:HS2.376349.1.A1_3P_AT amine oxidase (flavin containing) domain 2 hs
U133_X3P:HS.174174.0.A1_3P_S_AT amine oxidase (flavin containing) domain 2 hs
HG-U133_PLUS_2:1555897_AT amine oxidase (flavin containing) domain 2 hs
HG-U133A_2:212348_S_AT amine oxidase (flavin containing) domain 2 hs
HG-U133_PLUS_2:212348_S_AT amine oxidase (flavin containing) domain 2 hs
HG-U133A:212348_S_AT amine oxidase (flavin containing) domain 2 hs
HG-U95AV2:41122_AT amine oxidase (flavin containing) domain 2 hs
HG-U95B:44204_AT amine oxidase (flavin containing) domain 2 hs
HG-U133_PLUS_2:238652_AT Amine oxidase (flavin containing) domain 2 hs
HG-U133B:238652_AT Amine oxidase (flavin containing) domain 2 hs
HG-U95C:51127_AT Amine oxidase (flavin containing) domain 2 hs
U133_X3P:HS.313541.0.A1_3P_AT Amine oxidase (flavin containing) domain 2 hs
MU11KSUBB:Z31278_S_AT amine oxidase (flavin containing) domain 2 mm
MG-U74AV2:98889_AT amine oxidase (flavin containing) domain 2 mm
MOE430A:1426762_S_AT amine oxidase (flavin containing) domain 2 mm
MOUSE430A_2:1426762_S_AT amine oxidase (flavin containing) domain 2 mm
MOUSE430_2:1426762_S_AT amine oxidase (flavin containing) domain 2 mm
MOE430A:1426761_AT amine oxidase (flavin containing) domain 2 mm
MOUSE430A_2:1426761_AT amine oxidase (flavin containing) domain 2 mm
MOUSE430_2:1426761_AT amine oxidase (flavin containing) domain 2 mm
MU19KSUBB:TC31678_AT Amine oxidase (flavin containing) domain 2, mRNA (cDNA clone IMAGE:4019315) mm
RG-U34C:RC_AI229502_AT similar to AOF2 protein rn
RAE230A:1372007_AT similar to AOF2 protein rn
RAT230_2:1372007_AT similar to AOF2 protein rn
RAE230B:1382483_AT Similar to AOF2 protein rn
RAT230_2:1382483_AT Similar to AOF2 protein rn
RG-U34B:RC_AA850438_AT Similar to AOF2 protein rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA21604 Hypothetical protein Y40B1B.6 [Caenorhabditis elegans] ref|NP_493366.1| Suppressor of PResenilin defect family member (spr-5) [Caenorhabditis elegans] sp|Q9XWP6|SPR5_CAEEL Suppressor of presenilin 5 (P110b homolog) gb|AAN62580.1| suppressor of presenilin 5; Y40B1B.6 [Caenorhabditis elegans] 0.0
blast CAE63535 Hypothetical protein CBG08015 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR007526 EMBL-EBI SWIRM 5.7E-32
Pfam IPR002937 EMBL-EBI Amine oxidase 8.6E-94
Sequence
Target Sequence 
>C. ELEGANS:182059_S_AT
gcgaagaggcaatgctcgagctacccgatgacgtcataattcaaaatgcgatgataaatc
ttcaaaaagcatttggaaataattgtccacgtgctccaatcagtgcacatattacacgtt
ggcatgatgatgagttggcatttggatccggtgcatttatgagcttaaggactgaaacta
caagctttgatgacgtcatggaacccctcaaaacctccgatggaatgtcacgggtctatt
ttgctggagaacacacgtgttccagctatacatcgacgattcaaggagcatggatgtctg
gggcgagagccgccgccgacatttccaacgatcatattggcatcggctttgtggatataa
gtggaacacgtggtcaacgcggtgatg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCGAAGAGGCAATGCTCGAGCTACC 443 289 1718 Antisense
TCGAGCTACCCGATGACGTCATAAT 327 603 1733 Antisense
TGTCCACGTGCTCCAATCAGTGCAC 345 557 1801 Antisense
AGTGCACATATTACACGTTGGCATG 147 59 1819 Antisense
GAGTTGGCATTTGGATCCGGTGCAT 406 397 1849 Antisense
GAATGTCACGGGTCTATTTTGCTGG 306 331 1940 Antisense
CACGTGTTCCAGCTATACATCGACG 403 199 1971 Antisense
AAGGAGCATGGATGTCTGGGGCGAG 96 161 2000 Antisense
CGCCGACATTTCCAACGATCATATT 430 257 2031 Antisense
GATCATATTGGCATCGGCTTTGTGG 199 421 2047 Antisense
GGAACACGTGGTCAACGCGGTGATG 308 529 2080 Antisense
Sequence Source Affymetrix Proprietary Database