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[182018_at]

Description K07H8.1 /REP_DB=WormBase Gene ID /WP=CE18021 /TR=Q20068 /GB=AAC04426.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 98      6grp_high1_10_10 > 89      4grp_highest_8_8 > 53      4grp_high_8_8 > 17      6grp_highest_nonorm > 82      6grp_total > 96      4grp_total > 30      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 186
1 2 3 4 range
A 369.5
(0.9)
P
298.5
(-2)
P
273.7
(-3)
P
422.5
(3)
P
149
B 414.8
(3)
P
252.6
(-2.5)
P
236.6
(-3)
P
274.1
(-1.7)
P
178
C 367.9
(3)
P
290.7
(-2.3)
P
280.2
(-3)
P
303.7
(-1.4)
P
88
avr 384.1
(3)
280.6
(-2.1)
263.5
(-3)
333.4
(0.5)
121

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 241
1 2 3 4 5 6 range
A 366
(0)
P
308.5
(-1.7)
P
262.9
(-3)
P
321.8
(-1.3)
P
466.4
(3)
P
422.2
(1.7)
P
204
B 362.3
(-0.6)
P
327.8
(-1.8)
P
291.1
(-3)
P
378.3
(-0.1)
P
423
(1.4)
P
472.1
(3)
P
181
C 310.4
(-1.9)
P
329.7
(-1.4)
P
267.5
(-3)
P
396.8
(0.3)
P
356.8
(-0.7)
P
503.5
(3)
P
236
avr 346.2
(-0.7)
322
(-1.5)
273.8
(-3)
365.6
(-0.1)
415.4
(1.4)
465.9
(3)
192
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 83
1 2 3 4 range
A 134.5
(3)
P
64.8
(-2.8)
P
71.5
(-2.2)
P
61.9
(-3)
P
73
B 132.3
(3)
P
62.4
(-2.4)
P
54.8
(-3)
P
58.4
(-2.7)
P
78
C 121.8
(3)
P
83.6
(-0.2)
P
97.6
(0.9)
P
51.2
(-3)
P
71
avr 129.5
(3)
70.3
(-1.9)
74.6
(-1.6)
57.2
(-3)
72

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 119
1 2 3 4 5 6 range
A 67.5
(-2.3)
P
109.7
(0.8)
P
57.3
(-3)
P
81.6
(-1.3)
P
140.7
(3)
P
102.8
(0.3)
P
83
B 126.1
(0.2)
P
109.1
(-0.8)
P
70.7
(-3)
P
100.2
(-1.3)
P
171.9
(2.8)
P
176
(3)
P
105
C 115
(-0.2)
P
100.6
(-1.1)
P
68.1
(-3)
P
79.8
(-2.3)
P
115.4
(-0.2)
P
168.5
(3)
P
100
avr 102.9
(-0.3)
106.5
(-0.1)
65.4
(-3)
87.2
(-1.4)
142.7
(2.5)
149.1
(3)
84
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 182018_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8476
Sequence Type Exemplar sequence
Representative Public ID K07H8.1 NCBI
Target Description K07H8.1 /REP_DB=WormBase Gene ID /WP=CE18021 /TR=Q20068 /GB=AAC04426.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068994(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_068994 NCBI Caenorhabditis elegans K07H8.1 (K07H8.1) mRNA, complete cds. 11/11 None
K07H8.1 ENSEMBL cdna:known chromosome:CEL140:IV:8294672:8298005:1 gene:K07H8.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000039421 8/11 Cross Hyb Matching Probes None
GENEFINDER00000039434 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:8294677-8297183(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl K07H8.1
Entrez Gene 177624 Entrez gene
SwissProt Q20068 EMBL-EBI
WormBase CE18021 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:259895_AT tubulin folding cofactor E / Pfifferling (PFI) at
CANINE:1585098_AT similar to beta-tubulin cofactor E cfa
CANINE:1585340_S_AT similar to beta-tubulin cofactor E cfa
CANINE:1585339_AT similar to beta-tubulin cofactor E cfa
CANINE_2:CFA.9069.1.A1_AT similar to beta-tubulin cofactor E cfa
CANINE_2:CFAAFFX.17600.1.S1_S_AT similar to beta-tubulin cofactor E cfa
DROSOPHILA_2:1640333_AT dm
DROSGENOME1:153292_AT dm
CHICKEN:GGAAFFX.24314.1.S1_AT similar to tubulin-folding protein TBCE gga
CHICKEN:GGAAFFX.24314.2.S1_AT similar to tubulin-folding protein TBCE gga
CHICKEN:GGAAFFX.24314.2.S1_S_AT similar to tubulin-folding protein TBCE gga
HG-U133_PLUS_2:203715_AT tubulin-specific chaperone e hs
HG-U133A:203715_AT tubulin-specific chaperone e hs
HG-U133A_2:203715_AT tubulin-specific chaperone e hs
HG-U133_PLUS_2:203714_S_AT tubulin-specific chaperone e hs
HG-U133A:203714_S_AT tubulin-specific chaperone e hs
HG-FOCUS:203714_S_AT tubulin-specific chaperone e hs
HG-U133A_2:203714_S_AT tubulin-specific chaperone e hs
HG-U95AV2:35159_AT tubulin-specific chaperone e hs
HUGENEFL:U61232_AT tubulin-specific chaperone e hs
U133_X3P:G6006029_3P_A_AT tubulin-specific chaperone e hs
HG-U95D:85312_AT tubulin-specific chaperone e hs
HG-U95B:43787_AT Tubulin-specific chaperone e hs
HG-U95C:51338_AT Tubulin-specific chaperone e hs
HU35KSUBB:RC_AA083952_AT Tubulin-specific chaperone e hs
MOUSE430A_2:1428282_AT tubulin-specific chaperone e mm
MOE430A:1428282_AT tubulin-specific chaperone e mm
MOUSE430_2:1428282_AT tubulin-specific chaperone e mm
MG-U74AV2:160140_AT tubulin-specific chaperone e mm
MU19KSUBC:TC40251_AT Tubulin-specific chaperone e (Tbce), mRNA mm
RG-U34A:RC_AA892313_AT tubulin-specific chaperone e (predicted) rn
RAE230A:1388869_AT tubulin-specific chaperone e (predicted) rn
RAT230_2:1388869_AT tubulin-specific chaperone e (predicted) rn
RG-U34C:RC_AI171759_AT Tubulin-specific chaperone e (predicted) rn
Protein Similarities
Method ID Description E-Value
blast AAC04426 Hypothetical protein K07H8.1 [Caenorhabditis elegans] ref|NP_501395.1| K07H8.1 [Caenorhabditis elegans] 0.0
blast CAE58450 Hypothetical protein CBG01587 [Caenorhabditis briggsae] 0.0
blast NP_848027 tubulin-specific chaperone e [Mus musculus] dbj|BAE39475.1| unnamed protein product [Mus musculus] gb|AAL92570.1| tubulin-folding protein TBCE [Mus musculus] gb|AAH50206.1| Tubulin-specific chaperone e [Mus musculus] 1.0E-42
Protein Domains
Database ID Description E-Value
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.068
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.029
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.048
Pfam IPR000938 EMBL-EBI CAP-Gly domain 7.1E-29
Sequence
Target Sequence
>C. ELEGANS:182018_AT
tcccgaaactcgaatatctgaacataaaaagaaattcaattgttgaatggaaaagtgtaa
attccattagatctcttaaaagtttgaaacggttattgttcgattgcaaaaaattatcaa
ctgaaaagggtgtccatgcctatgagattgtaattgccaagttgagcactttaatagatc
tcaataggtttgatgtgtcagaagtagaacgaaggtctgcagaaattcgatttctgaaca
aatatgccggtctaaatgataacgaagatcatcaagacgatatcaaaagactgattgaaa
ttcatggagaaccgacacttgatacagcaaaaaagggccttgcggtggtgaaaattagaa
ttgaatgtggaaatcgagtggagacacgaaggcttccattgggaatgagcatacagaaaa
ttagagatatgctcgctcgtctcttcaaagtccccaatacatcgaaaatccgtctatacc
tcgttatgagtgaaaaagccaaacaacaccgaattgaactagaaaatccgttaagagaat
ttggacactattcaccttcaga


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
TCCCGAAACTCGAATATCTGAACAT 429 595 899 Antisense
GTGTAAATTCCATTAGATCTCTTAA 182 487 953 Antisense
GGGTGTCCATGCCTATGAGATTGTA 74 499 1026 Antisense
TTCTGAACAAATATGCCGGTCTAAA 27 695 1130 Antisense
GGAGAACCGACACTTGATACAGCAA 425 519 1204 Antisense
AGGGCCTTGCGGTGGTGAAAATTAG 349 53 1232 Antisense
GGAGACACGAAGGCTTCCATTGGGA 629 519 1278 Antisense
TTAGAGATATGCTCGCTCGTCTCTT 591 681 1319 Antisense
CTCTTCAAAGTCCCCAATACATCGA 107 229 1339 Antisense
AATCCGTCTATACCTCGTTATGAGT 424 167 1365 Antisense
AATTTGGACACTATTCACCTTCAGA 652 173 1436 Antisense
Sequence Source Affymetrix Proprietary Database