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[181378_at]

Description C18H2.4 /REP_DB=WormBase Gene ID /WP=CE00762 /TR=Q18105 /GB=AAA50666.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Cluster 6grp_total > 79      4grp_total > 33      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 62
1 2 3 4 range
A 6.5
(-3)
A 		36.3
(0.9)
A 		51.9
(3)
A 		32.5
(0.4)
A 		45
B 20.1
(-3)
A 		51.3
(0.9)
A 		45.1
(0.1)
A 		68
(3)
A 		48
C 8.7
(-3)
A 		31.9
(0.8)
A 		21.7
(-0.9)
A 		45.4
(3)
A 		37
avr 11.8
(-3) 		39.8
(1.6) 		39.6
(1.5) 		48.6
(3) 		37

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 42
1 2 3 4 5 6 range
A 7
(-3)
A 		22
(0.1)
A 		30.6
(1.9)
A 		25.4
(0.8)
A 		13.5
(-1.6)
A 		35.7
(3)
A 		29
B 25.6
(0.3)
A 		44.6
(3)
A 		19.4
(-0.6)
A 		2.9
(-3)
A 		15.8
(-1.1)
A 		37.7
(2)
A 		42
C 9.4
(-2)
A 		30.5
(1.5)
A 		3.5
(-3)
A 		7.6
(-2.3)
A 		37.7
(2.7)
A 		39.5
(3)
A 		36
avr 14
(-2.5) 		32.4
(1.8) 		17.8
(-1.6) 		12
(-3) 		22.3
(-0.6) 		37.6
(3) 		26
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12
1 2 3 4 range
A 2.4
(-3)
A 		7.9
(-0.1)
A 		13.6
(3)
A 		4.8
(-1.7)
A 		11
B 6.4
(-3)
A 		12.7
(1.7)
A 		10.5
(0)
A 		14.5
(3)
A 		8
C 2.9
(-3)
A 		9.2
(3)
A 		7.6
(1.5)
A 		7.7
(1.6)
A 		6
avr 3.9
(-3) 		9.9
(2.4) 		10.6
(3) 		9
(1.6) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 14
1 2 3 4 5 6 range
A 1.3
(-3)
A 		7.8
(2.3)
A 		6.7
(1.4)
A 		6.5
(1.2)
A 		4.1
(-0.7)
A 		8.7
(3)
A 		7
B 8.9
(0.5)
A 		14.8
(3)
A 		4.7
(-1.3)
A 		0.8
(-3)
A 		6.4
(-0.6)
A 		14.1
(2.7)
A 		14
C 3.5
(-1.7)
A 		9.3
(1.1)
A 		0.9
(-3)
A 		1.5
(-2.7)
A 		12.2
(2.5)
A 		13.2
(3)
A 		12
avr 4.6
(-1.9) 		10.6
(2.1) 		4.1
(-2.2) 		2.9
(-3) 		7.6
(0.1) 		12
(3) 		9
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 181378_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6617
Sequence Type Exemplar sequence
Representative Public ID C18H2.4 NCBI
Target Description C18H2.4 /REP_DB=WormBase Gene ID /WP=CE00762 /TR=Q18105 /GB=AAA50666.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066276(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066276 NCBI Caenorhabditis elegans C18H2.4 (C18H2.4) mRNA, complete cds. 11/11 None
C18H2.4 ENSEMBL cdna:known chromosome:CEL140:III:7694613:7700255:1 gene:C18H2.4 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000029919 3/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:7694610-7700253(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl C18H2.4
Entrez Gene 182800 Entrez gene
SwissProt Q18105 EMBL-EBI
WormBase CE00762 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA50666 Hypothetical protein C18H2.4 [Caenorhabditis elegans] ref|NP_498677.1| C18H2.4 [Caenorhabditis elegans] 0.0
blast AAC19199 Hypothetical protein F56H1.3 [Caenorhabditis elegans] ref|NP_491670.1| F56H1.3 [Caenorhabditis elegans] 6.0E-91
blast AAM22033 Hypothetical protein C18H2.3 [Caenorhabditis elegans] ref|NP_498676.2| C18H2.3 [Caenorhabditis elegans] 3.0E-88
Protein Domains
Database ID Description E-Value
Pfam IPR003125 EMBL-EBI Protein of unknown function WSN 3.5E-28
Pfam IPR001357 EMBL-EBI BRCT 3.5E-11
Pfam IPR001357 EMBL-EBI BRCT 0.83
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_498677.1 1 615-637
C18H2.4 1 615-637
Sequence
Target Sequence 
>C. ELEGANS:181378_AT
agacaaacgcagacgctttgcctactacaactcattgtattgtaaagaccgaccccgatg
gaactttggaaaccgataatattgatttattgatttggattttcaatggagtaattattg
taaaagagtcttggatgacggattgcttggaaaataagaaattgattgaaaaagacagtg
actatttggtggaaaaagtgaaatacaagggtactgtctatggtacagtaattcaatggt
ccgaagcaatggccaaaggaactatgccgtatcttcatggagtttatgcatcaattttaa
ttgaagacaagactaattatccaacacttgtctctatcataactacccacggaggaacaa
ttgtcgtcgatcctaaagtactttcaaacttaaatcagggatcccatccatatcttcact
ccaatctcggatcatttttcattattcatgacggtcgacccgatttgagacagt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGACAAACGCAGACGCTTTGCCTAC 603 71 2213 Antisense
GCTTTGCCTACTACAACTCATTGTA 25 305 2227 Antisense
TGTAAAGACCGACCCCGATGGAACT 709 555 2253 Antisense
GGAACTATGCCGTATCTTCATGGAG 621 529 2470 Antisense
ATTATCCAACACTTGTCTCTATCAT 701 13 2528 Antisense
GTCTCTATCATAACTACCCACGGAG 184 471 2542 Antisense
TGTCGTCGATCCTAAAGTACTTTCA 538 555 2574 Antisense
ATCAGGGATCCCATCCATATCTTCA 228 29 2606 Antisense
ATATCTTCACTCCAATCTCGGATCA 77 21 2622 Antisense
ATCTCGGATCATTTTTCATTATTCA 24 33 2636 Antisense
GACGGTCGACCCGATTTGAGACAGT 188 377 2662 Antisense
Sequence Source Affymetrix Proprietary Database