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[180891_at] 7TM receptor, sre family

Description F40G12.1 /REP_DB=WormBase Gene ID /WP=CE10176 /TR=Q20249 /GB=CAB01186.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_total > 54      4grp_total > 09      6grp_cgc > 56      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 112
1 2 3 4 range
A 22.1
(-3)
A 		25.6
(-2.8)
A 		30.2
(-2.6)
A 		133.7
(3)
P 		112
B 46.3
(-3)
P 		51
(-2.4)
A 		63.2
(-0.8)
A 		92.1
(3)
P 		46
C 26.3
(-3)
A 		56.7
(-0.9)
P 		50.8
(-1.3)
A 		113.1
(3)
P 		87
avr 31.6
(-3) 		44.4
(-2.1) 		48.1
(-1.8) 		113
(3) 		81

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 56
1 2 3 4 5 6 range
A 46.2
(-0.2)
A 		31
(-2)
A 		73.2
(3)
P 		22.9
(-3)
A 		32.8
(-1.8)
A 		38.3
(-1.2)
A 		50
B 22.6
(-2)
A 		32.2
(-0.2)
A 		49.9
(3)
P 		16.9
(-3)
A 		32.2
(-0.2)
P 		40.1
(1.2)
A 		33
C 29
(-3)
A 		50.3
(0.3)
P 		29.9
(-2.9)
A 		68.3
(3)
A 		31.3
(-2.6)
A 		59.8
(1.7)
A 		39
avr 32.6
(-2.8) 		37.8
(-1.2) 		51
(3) 		36
(-1.8) 		32.1
(-3) 		46.1
(1.4) 		19
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 8.1
(-1.9)
A 		5.5
(-3)
A 		7.9
(-2)
A 		19.6
(3)
P 		14
B 14.8
(-1.1)
P 		12.6
(-3)
A 		14.6
(-1.3)
A 		19.6
(3)
P 		7
C 8.7
(-3)
A 		16.3
(1.4)
P 		17.7
(2.2)
A 		19.1
(3)
P 		10
avr 10.5
(-3) 		11.5
(-2.3) 		13.4
(-1) 		19.4
(3) 		9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 16
1 2 3 4 5 6 range
A 8.5
(-1.4)
A 		11
(0.1)
A 		15.9
(3)
P 		5.8
(-3)
A 		9.9
(-0.6)
A 		9.3
(-0.9)
A 		10
B 7.9
(-1)
A 		10.7
(0.6)
A 		12.1
(1.4)
P 		4.5
(-3)
A 		13.1
(2)
P 		14.9
(3)
A 		10
C 10.7
(-1.5)
A 		15.4
(0.8)
P 		7.6
(-3)
A 		13.7
(-0)
A 		10.1
(-1.8)
A 		20
(3)
A 		12
avr 9
(-2.1) 		12.4
(0.9) 		11.9
(0.5) 		8
(-3) 		11
(-0.3) 		14.7
(3) 		7
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 180891_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14453
Sequence Type Exemplar sequence
Representative Public ID F40G12.1 NCBI
Target Description F40G12.1 /REP_DB=WormBase Gene ID /WP=CE10176 /TR=Q20249 /GB=CAB01186.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074127(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074127 NCBI Caenorhabditis elegans Serpentine Receptor, class E (epsilon) family member (sre-8) (sre-8) mRNA, complete cds. 11/11 None
SNAP00000026726 ENSEMBL cdna:SNAP chromosome:CEL140:V:14259701:14261819:1 11/11 None
F40G12.1 ENSEMBL cdna:known chromosome:CEL140:V:14259701:14261819:1 gene:F40G12.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000026756 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:14259700-14261819(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM receptor, sre family
Gene Symbol sre-8
Ensembl F40G12.1
Entrez Gene 185561 Entrez gene
SwissProt Q20249 EMBL-EBI
WormBase CE10176 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7606 sensory perception of chemical stimulus inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01186 Hypothetical protein F40G12.1 [Caenorhabditis elegans] ref|NP_506528.1| Serpentine Receptor, class E (epsilon) family member (sre-8) [Caenorhabditis elegans] sp|Q20249|SRE8_CAEEL Serpentine receptor class epsilon-8 (Protein sre-8) 0.0
blast CAE60983 Hypothetical protein CBG04718 [Caenorhabditis briggsae] 1.0E-153
blast CAE60997 Hypothetical protein CBG04734 [Caenorhabditis briggsae] 1.0E-126
Protein Domains
Database ID Description E-Value
Pfam IPR004151 EMBL-EBI C. elegans Sre G protein-coupled chemoreceptor 5.4E-116
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506528.1 7 35-57,64-86,101-123,143-165,175-197,235-252,262-284
F40G12.1 7 35-57,64-86,101-123,143-165,175-197,235-252,262-284
SNAP00000026726 7 35-57,64-86,101-123,143-165,175-197,235-252,262-284
Sequence
Target Sequence 
>C. ELEGANS:180891_AT
aatcccgcaaaatctgggtgtctctcatgattctctccatttttcacccacttgtttttg
catctgctatcgcatatatacaatgttggatcccagtagtcgtccacgtcatctcttttt
tcattgttaatatcattggatacatagggattcacatttgttattcgtataatatcaaaa
aacatagaaaattttatagtccacaatgtatttcaagagttacatatggactcagtgaac
gatttcagttggcagaaaatatcaaaatgtgtaaagttctgaaaaaagttcaaatttcca
ttctcttcttcaatattggatgttgttcaattcttctaatggatcattttcaagtgaaaa
tgatgataatctactggtcctatgtgtgcttcaacttttttgcattagtttatggaatta
ctgtgcccatcattttgtactcggcacttccagaatggc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AATCCCGCAAAATCTGGGTGTCTCT 473 167 428 Antisense
AATCTGGGTGTCTCTCATGATTCTC 165 169 438 Antisense
ATTTTTCACCCACTTGTTTTTGCAT 416 15 466 Antisense
TTTGCATCTGCTATCGCATATATAC 222 669 484 Antisense
ATGTTGGATCCCAGTAGTCGTCCAC 306 3 510 Antisense
ACGTCATCTCTTTTTTCATTGTTAA 150 95 533 Antisense
TGGATGTTGTTCAATTCTTCTAATG 480 549 744 Antisense
TCTACTGGTCCTATGTGTGCTTCAA 69 615 797 Antisense
GTGTGCTTCAACTTTTTTGCATTAG 669 487 811 Antisense
TTACTGTGCCCATCATTTTGTACTC 542 683 845 Antisense
TTGTACTCGGCACTTCCAGAATGGC 454 705 862 Antisense
Sequence Source Affymetrix Proprietary Database