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[179630_at] G-protein coupled receptor, srh family

Description T19C9.3 /REP_DB=WormBase Gene ID /WP=CE16420 /TR=O45794 /GB=CAB07488.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_total > 81      4grp_total > 04      6grp_cgc > 86      6grp_cgc_sub > 04      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 46
1 2 3 4 range
A 13.3
(0.6)
A 		4.3
(-2.2)
A 		1.9
(-3)
A 		20.9
(3)
A 		19
B 14.9
(2.7)
A 		11.2
(1.2)
A 		1.2
(-3)
A 		15.5
(3)
A 		14
C 5.3
(-2.7)
A 		3.4
(-3)
A 		14.7
(-1.5)
A 		47.5
(3)
A 		44
avr 11.2
(-1.6) 		6.3
(-2.9) 		5.9
(-3) 		28
(3) 		22

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 29
1 2 3 4 5 6 range
A 9.3
(3)
A 		4.7
(-0.5)
A 		3.8
(-1.2)
A 		1.5
(-3)
A 		2.2
(-2.5)
A 		2.8
(-2)
A 		8
B 2.3
(-2.8)
A 		9.3
(0.1)
A 		10.4
(0.6)
A 		13.7
(2)
A 		16.2
(3)
A 		1.7
(-3)
A 		15
C 1.5
(-2.9)
A 		8
(-1.6)
A 		1
(-3)
A 		30.1
(3)
A 		15.5
(-0)
A 		1.4
(-2.9)
A 		29
avr 4.4
(-1.9) 		7.3
(-0.6) 		5.1
(-1.6) 		15.1
(3) 		11.3
(1.3) 		2
(-3) 		13
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 8
1 2 3 4 range
A 4.9
(3)
A 		0.9
(-2.5)
A 		0.5
(-3)
A 		3.1
(0.5)
A 		4
B 4.8
(3)
A 		2.8
(0.3)
A 		0.3
(-3)
A 		3.3
(1)
A 		5
C 1.7
(-2.4)
A 		1
(-3)
A 		5.1
(0.5)
A 		8
(3)
A 		7
avr 3.8
(1.1) 		1.6
(-3) 		2
(-2.3) 		4.8
(3) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 6
1 2 3 4 5 6 range
A 1.7
(3)
A 		1.7
(3)
A 		0.8
(-1.2)
A 		0.4
(-3)
A 		0.7
(-1.6)
A 		0.7
(-1.6)
A 		1
B 0.8
(-2.8)
A 		3.1
(-0.5)
A 		2.5
(-1.1)
A 		3.6
(0)
A 		6.6
(3)
A 		0.6
(-3)
A 		6
C 0.5
(-2.8)
A 		2.4
(-0.8)
A 		0.3
(-3)
A 		6.1
(3)
A 		5
(1.9)
A 		0.5
(-2.8)
A 		6
avr 1
(-2.3) 		2.4
(0.1) 		1.2
(-2) 		3.4
(1.8) 		4.1
(3) 		0.6
(-3) 		4
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 179630_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13105
Sequence Type Exemplar sequence
Representative Public ID T19C9.3 NCBI
Target Description T19C9.3 /REP_DB=WormBase Gene ID /WP=CE16420 /TR=O45794 /GB=CAB07488.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074961(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074961 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-252) (srh-252) mRNA, complete cds. 11/11 A 
SNAP00000010311 ENSEMBL cdna:SNAP chromosome:CEL140:V:17224757:17225982:-1 11/11 None
GENEFINDER00000010323 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:17224200:17226519:-1 11/11 None
T19C9.3 ENSEMBL cdna:known chromosome:CEL140:V:17224963:17225982:-1 gene:T19C9.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:17224962-17225982(-) 100.0 100.0
chrV:17483441-17484424(-) 90.15 90.15
Public Domain and Genome References
Gene Title G-protein coupled receptor, srh family
Gene Symbol srh-252
Ensembl T19C9.3
Entrez Gene 188598 Entrez gene
SwissProt O45794 EMBL-EBI
WormBase CE16420 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07488 Hypothetical protein T19C9.3 [Caenorhabditis elegans] ref|NP_507362.1| Serpentine Receptor, class H family member (srh-252) [Caenorhabditis elegans] 1.0E-171
blast CAB07488 Hypothetical protein T19C9.3 [Caenorhabditis elegans] ref|NP_507362.1| Serpentine Receptor, class H family member (srh-252) [Caenorhabditis elegans] 1.0E-165
blast T20585 hypothetical protein F08E10.5 - Caenorhabditis elegans 1.0E-149
blast T20585 hypothetical protein F08E10.5 - Caenorhabditis elegans 1.0E-146
blast CAB04630 Hypothetical protein R08H2.4 [Caenorhabditis elegans] ref|NP_506819.1| Serpentine Receptor, class H family member (srh-251) [Caenorhabditis elegans] 1.0E-124
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_507362.1 7 15-37,50-72,87-109,130-152,187-209,230-252,267-289
T19C9.3 7 15-37,50-72,87-109,130-152,187-209,230-252,267-289
SNAP00000010311 7 15-37,50-72,87-109,130-152,187-209,230-252,267-289
GENEFINDER00000010323 7 37-59,80-102,112-134,155-177,212-234,255-277,292-314
Sequence
Target Sequence 
>C. ELEGANS:179630_AT
agactctatctggcattacattagaaaagtctacctaccactgatgtacatattcccgct
caccttcacactgccaatctgggcagttatgccaatacaggaaaacgcacgcccatgcga
tgaggctttacaactggaaaatattcaaatggaatcgaaaaaaatattcattatatccgt
cgatccaataatttcagtcacttggggtgtgactaattgtatactcatcgttacacctat
cataacatttttcactttaacattcttccaactactcgaaaaccaaaaaacacacaaata
ttcctatcaaacaattcaactccagaagacttttctattgtctatgtcaatacaattcgg
ctctttttttgtcatcatatttattccggtgcttcttttgcacggctcggtcattttttg
gtatcatgatcaagttctcaacaactttatcacaatcatgttttcatcatttggaactgg
atccaccgtagtgatgattgtggtgtacaaaccgtacaggcggtttacgttttctgtttt
cttcgggaacaagca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGACTCTATCTGGCATTACATTAGA 613 71 372 Antisense
AAAGTCTACCTACCACTGATGTACA 671 121 397 Antisense
GCACGCCCATGCGATGAGGCTTTAC 582 315 478 Antisense
ACACCTATCATAACATTTTTCACTT 89 109 604 Antisense
ACTTTAACATTCTTCCAACTACTCG 57 103 625 Antisense
TATTCCTATCAAACAATTCAACTCC 92 665 670 Antisense
AACTCCAGAAGACTTTTCTATTGTC 155 143 689 Antisense
GTCTATGTCAATACAATTCGGCTCT 33 469 711 Antisense
ACGGCTCGGTCATTTTTTGGTATCA 25 95 773 Antisense
TTTGGAACTGGATCCACCGTAGTGA 703 661 841 Antisense
TTTCTGTTTTCTTCGGGAACAAGCA 254 671 902 Antisense
Sequence Source Affymetrix Proprietary Database