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[179244_s_at]

Description C47G2.3 /REP_DB=WormBase Gene ID /WP=CE25820 /TR=Q9NAQ9 /GB=CAB97233.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 67      6grp_high1_10_10 > 85      4grp_highest_8_8 > 12      4grp_high_8_8 > 39      6grp_highest_nonorm > 82      6grp_total > 75      4grp_total > 40      6grp_highest_sub > In      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 194
1 2 3 4 range
A 377
(-3)
P 		412
(-1.3)
P 		482.7
(2.2)
P 		498.9
(3)
P 		122
B 333.5
(-3)
P 		367.4
(-1.9)
P 		527.1
(3)
P 		403.5
(-0.8)
P 		194
C 390.1
(-3)
P 		497.5
(3)
P 		498.4
(3)
P 		445.9
(0.1)
P 		108
avr 366.9
(-3) 		425.6
(-0.4) 		502.7
(3) 		449.4
(0.6) 		136

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 410
1 2 3 4 5 6 range
A 174.9
(-3)
P 		381
(0.9)
P 		485.8
(2.9)
P 		429.5
(1.9)
P 		324.4
(-0.1)
P 		488.8
(3)
P 		314
B 346.1
(-2.1)
P 		316.1
(-3)
P 		424.5
(0.4)
P 		368.7
(-1.3)
P 		469.7
(1.8)
P 		506.6
(3)
P 		191
C 389.5
(-1.2)
P 		303.1
(-3)
P 		359.7
(-1.8)
P 		358.9
(-1.8)
P 		355.5
(-1.9)
P 		584.6
(3)
P 		282
avr 303.5
(-3) 		333.4
(-2.2) 		423.3
(0.2) 		385.7
(-0.8) 		383.2
(-0.9) 		526.7
(3) 		223
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 101
1 2 3 4 range
A 137.3
(3)
P 		89.4
(-1.5)
P 		126.2
(2)
P 		73
(-3)
P 		64
B 106.3
(0.4)
P 		90.7
(-2.2)
P 		122.1
(3)
P 		86
(-3)
P 		36
C 129.1
(0.3)
P 		143
(1.1)
P 		173.7
(3)
P 		75.2
(-3)
P 		99
avr 124.2
(1.4) 		107.7
(-0.2) 		140.7
(3) 		78.1
(-3) 		63

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 164
1 2 3 4 5 6 range
A 32.2
(-3)
P 		135.5
(3)
P 		105.8
(1.3)
P 		108.9
(1.5)
P 		97.9
(0.8)
P 		119
(2)
P 		103
B 120.4
(-1.5)
P 		105.2
(-2.5)
P 		103.1
(-2.7)
P 		97.7
(-3)
P 		190.8
(3)
P 		188.9
(2.9)
P 		93
C 144.4
(0.5)
P 		92.5
(-2)
P 		91.6
(-2.1)
P 		72.2
(-3)
P 		115
(-0.9)
P 		195.7
(3)
P 		124
avr 99
(-2.5) 		111.1
(-1.5) 		100.2
(-2.4) 		92.9
(-3) 		134.6
(0.3) 		167.9
(3) 		75
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 179244_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3202
Sequence Type Exemplar sequence
Representative Public ID C47G2.3 NCBI
Target Description C47G2.3 /REP_DB=WormBase Gene ID /WP=CE25820 /TR=Q9NAQ9 /GB=CAB97233.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064011(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_064011 NCBI Caenorhabditis elegans C47G2.3 (C47G2.3) mRNA, complete cds. 11/11 None
SNAP00000012595 ENSEMBL cdna:SNAP chromosome:CEL140:II:11288712:11290065:-1 11/11 None
GENEFINDER00000012602 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:11288712:11293382:-1 11/11 None
C47G2.3.1 ENSEMBL cdna:known chromosome:CEL140:II:11288605:11290067:-1 gene:C47G2.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:11288708-11290062(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl C47G2.3
Entrez Gene 174722 Entrez gene
SwissProt Q9NAQ9 EMBL-EBI
WormBase CE25820 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:261664_S_AT mitochondrial import inner membrane translocase subunit Tim17/Tim22/Tim23 family protein at
CANINE:1589454_S_AT similar to Mitochondrial import inner membrane translocase subunit Tim22 cfa
CANINE:1589453_AT similar to Mitochondrial import inner membrane translocase subunit Tim22 cfa
CANINE_2:CFAAFFX.29119.1.S1_AT similar to Mitochondrial import inner membrane translocase subunit Tim22 cfa
DROSOPHILA_2:1630351_AT dm
CHICKEN:GGA.8053.1.S1_AT similar to TIM22 preprotein translocase gga
HG-U133_PLUS_2:219184_X_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U133A:219184_X_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-FOCUS:219184_X_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U133A_2:219184_X_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HU35KSUBC:RC_AA242762_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
U133_X3P:G7019552_3P_A_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
U133_X3P:HS.87595.1.A1_3P_A_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
U133_X3P:HS.87595.0.S1_3P_A_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U133_PLUS_2:222841_S_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U133B:222841_S_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U133_PLUS_2:229100_S_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U133B:229100_S_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U95C:50224_S_AT translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U133_PLUS_2:231400_S_AT Translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U133B:231400_S_AT Translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U95B:58660_S_AT Translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HG-U95C:63944_AT Translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HU35KSUBA:AA455318_AT Translocase of inner mitochondrial membrane 22 homolog (yeast) hs
HU35KSUBA:RC_AA421611_AT Translocase of inner mitochondrial membrane 22 homolog (yeast) hs
U133_X3P:HS.87595.2.A1_3P_AT Translocase of inner mitochondrial membrane 22 homolog (yeast) hs
MOE430A:1448517_AT translocase of inner mitochondrial membrane 22 homolog (yeast) mm
MOUSE430A_2:1448517_AT translocase of inner mitochondrial membrane 22 homolog (yeast) mm
MOUSE430_2:1448517_AT translocase of inner mitochondrial membrane 22 homolog (yeast) mm
MG-U74AV2:93348_AT translocase of inner mitochondrial membrane 22 homolog (yeast) mm
MOE430A:1448518_AT translocase of inner mitochondrial membrane 22 homolog (yeast) mm
MOUSE430A_2:1448518_AT translocase of inner mitochondrial membrane 22 homolog (yeast) mm
MOUSE430_2:1448518_AT translocase of inner mitochondrial membrane 22 homolog (yeast) mm
MU19KSUBB:TC27213_AT Translocase of inner mitochondrial membrane 22 homolog (yeast), mRNA (cDNA clone IMAGE:4167149) mm
RAE230A:1375565_AT translocase of inner mitochondrial membrane 22 homolog (yeast) rn
RAT230_2:1375565_AT translocase of inner mitochondrial membrane 22 homolog (yeast) rn
RAE230A:1370353_AT translocase of inner mitochondrial membrane 22 homolog (yeast) rn
RAT230_2:1370353_AT translocase of inner mitochondrial membrane 22 homolog (yeast) rn
RG-U34C:RC_AI103112_AT Translocase of inner mitochondrial membrane 22 homolog (yeast) rn
YEAST_2:1773645_AT Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5744 mitochondrial inner membrane presequence translocase complex inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
15450 protein translocase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88936 Hypothetical protein C47G2.4 [Caenorhabditis elegans] ref|NP_496413.1| C47G2.4 [Caenorhabditis elegans] 0.0
blast CAE59539 Hypothetical protein CBG02934 [Caenorhabditis briggsae] 0.0
blast CAB97233 Hypothetical protein C47G2.3 [Caenorhabditis elegans] ref|NP_496412.1| C47G2.3 [Caenorhabditis elegans] 1.0E-111
blast CAB97233 Hypothetical protein C47G2.3 [Caenorhabditis elegans] ref|NP_496412.1| C47G2.3 [Caenorhabditis elegans] 1.0E-110
blast CAE59540 Hypothetical protein CBG02935 [Caenorhabditis briggsae] 1.0E-106
blast EAA08395 ENSANGP00000014763 [Anopheles gambiae str. PEST] ref|XP_312898.2| ENSANGP00000014763 [Anopheles gambiae str. PEST] 5.0E-27
Protein Domains
Database ID Description E-Value
Pfam IPR003397 EMBL-EBI Mitochondrial import inner membrane translocase, subunit Tim17/22 2.2E-46
Pfam IPR003397 EMBL-EBI Mitochondrial import inner membrane translocase, subunit Tim17/22 2.2E-46
Pfam IPR006876 EMBL-EBI LMBR1-like conserved region 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496412.1 2 93-112,185-207
C47G2.3.1 2 93-112,185-207
SNAP00000012595 2 93-112,185-207
GENEFINDER00000012602 11 4-26,39-61,111-133,140-162,182-204,368-390,414-433,454-476,503-525,770-789,862-884
Sequence
Target Sequence 
>C. ELEGANS:179244_S_AT
gcgacctcaatggaagagctcttcggaaatccgttcaggccgaaaaaagagcgagtcgtc
gtcgaggagaagccattcgagtacacaccatcagcatacgttcagatgattgatcagatg
atcggaatcaaaacgaggccgtggaatccagaacgtacgccaattaaaccgattcaaatg
ctcacactacccgagatgtcacgagaagaacgatggattcaatggggaatggagaattgt
acggtgaaagcatcgatttctggagtgctcggagttggagtcggattcgctttcggactt
ttcaccgcttcagttgatccgcagctatcgatggttggaggagatcctacgaaacagcta
accctaaaacaaacgtggaaagaaatgtcaagtcgaatgaaatcctacggaaagaacttt
ggatccatcggtttaatgttttccggaaccgaatgcgccctggaaacgatccgtgcaaaa
agcgactggcgcaacggaacctattctggag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCGACCTCAATGGAAGAGCTCTTCG 591 289 34 Antisense
GCTCTTCGGAAATCCGTTCAGGCCG 250 301 51 Antisense
AAAGAGCGAGTCGTCGTCGAGGAGA 308 121 79 Antisense
TACACACCATCAGCATACGTTCAGA 386 643 115 Antisense
GCCGTGGAATCCAGAACGTACGCCA 186 263 171 Antisense
CAAATGCTCACACTACCCGAGATGT 294 193 208 Antisense
GATTTCTGGAGTGCTCGGAGTTGGA 180 429 288 Antisense
GTTGGAGTCGGATTCGCTTTCGGAC 209 437 307 Antisense
CAGTTGATCCGCAGCTATCGATGGT 172 205 344 Antisense
GATCCGTGCAAAAAGCGACTGGCGC 267 417 501 Antisense
TGGCGCAACGGAACCTATTCTGGAG 213 543 520 Antisense
Sequence Source Affymetrix Proprietary Database