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[178228_at] 7TM chemoreceptor, sri family

Description T22H2.1 /REP_DB=WormBase Gene ID /WP=CE13996 /TR=O18113 /GB=CAB04753.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation
Cluster 6grp_total > 0      4grp_total > 30      6grp_total_sub > Hat      6grp_cgc > 64      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 14
1 2 3 4 range
A 12
(3)
A 		6.7
(-2.3)
A 		6
(-3)
A 		11.2
(2.2)
A 		6
B 19.5
(3)
A 		8.9
(-1.6)
A 		5.6
(-3)
A 		8.3
(-1.8)
A 		14
C 13.4
(0.3)
A 		9.7
(-1.3)
A 		5.6
(-3)
A 		19.7
(3)
A 		14
avr 15
(3) 		8.4
(-1.3) 		5.7
(-3) 		13.1
(1.8) 		9

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 8.6
(-1.4)
A 		8.8
(-1.4)
A 		7.3
(-1.8)
A 		3.5
(-3)
A 		22.8
(3)
A 		5.5
(-2.4)
A 		19
B 5.2
(-2.3)
A 		5
(-2.4)
A 		5.3
(-2.2)
A 		7.4
(-1.3)
A 		3.7
(-3)
A 		16.4
(3)
A 		13
C 3.9
(-3)
A 		29.3
(3)
A 		6.5
(-2.4)
A 		12.6
(-0.9)
A 		9.1
(-1.8)
A 		13.6
(-0.7)
A 		25
avr 5.9
(-3) 		14.4
(3) 		6.4
(-2.6) 		7.8
(-1.7) 		11.9
(1.2) 		11.8
(1.2) 		9
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5
1 2 3 4 range
A 4.4
(3)
A 		1.4
(-3)
A 		1.6
(-2.6)
A 		1.6
(-2.6)
A 		3
B 6.2
(3)
A 		2.2
(-1.9)
A 		1.3
(-3)
A 		1.8
(-2.4)
A 		5
C 4.4
(3)
A 		2.8
(-1)
A 		2
(-3)
A 		3.3
(0.2)
A 		2
avr 5
(3) 		2.1
(-2.1) 		1.6
(-3) 		2.2
(-1.9) 		3

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 8
1 2 3 4 5 6 range
A 1.6
(-2.3)
A 		3.1
(-0.8)
A 		1.6
(-2.3)
A 		0.9
(-3)
A 		6.9
(3)
A 		1.3
(-2.6)
A 		6
B 1.8
(-2.4)
A 		1.7
(-2.5)
A 		1.3
(-3)
A 		2
(-2.1)
A 		1.5
(-2.8)
A 		6.1
(3)
A 		5
C 1.4
(-3)
A 		8.9
(3)
A 		1.7
(-2.8)
A 		2.5
(-2.1)
A 		3
(-1.7)
A 		4.6
(-0.4)
A 		8
avr 1.6
(-2.8) 		4.6
(3) 		1.5
(-3) 		1.8
(-2.4) 		3.8
(1.5) 		4
(1.8) 		3
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 178228_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1661
Sequence Type Exemplar sequence
Representative Public ID T22H2.1 NCBI
Target Description T22H2.1 /REP_DB=WormBase Gene ID /WP=CE13996 /TR=O18113 /GB=CAB04753.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060579(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060579 NCBI Caenorhabditis elegans Serpentine Receptor, class I family member (sri-12) (sri-12) mRNA, complete cds. 9/11 None
SNAP00000038044 ENSEMBL cdna:SNAP chromosome:CEL140:I:11707706:11709300:1 9/11 None
T22H2.1 ENSEMBL cdna:known chromosome:CEL140:I:11707291:11709300:1 gene:T22H2.1 9/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000038049 7/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:11707221-11709231(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, sri family
Gene Symbol sri-12
Ensembl T22H2.1
Entrez Gene 188763 Entrez gene
SwissProt O18113 EMBL-EBI
WormBase CE33705 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6979 response to oxidative stress inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4601 peroxidase activity inferred from electronic annotation QuickGO AmiGO
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04753 Hypothetical protein T22H2.1 [Caenorhabditis elegans] ref|NP_492980.2| Serpentine Receptor, class I family member (sri-12) [Caenorhabditis elegans] 0.0
blast CAB04750 Hypothetical protein T22H2.3 [Caenorhabditis elegans] ref|NP_492979.2| Serpentine Receptor, class I family member (sri-11) [Caenorhabditis elegans] 1.0E-132
blast CAE69304 Hypothetical protein CBG15360 [Caenorhabditis briggsae] 1.0E-122
blast CAB04753 Hypothetical protein T22H2.1 [Caenorhabditis elegans] ref|NP_492980.2| Serpentine Receptor, class I family member (sri-12) [Caenorhabditis elegans] 1.0E-110
blast CAB04750 Hypothetical protein T22H2.3 [Caenorhabditis elegans] ref|NP_492979.2| Serpentine Receptor, class I family member (sri-11) [Caenorhabditis elegans] 3.0E-72
blast CAB03997 Hypothetical protein C54E10.4 [Caenorhabditis elegans] ref|NP_507674.2| Serpentine Receptor, class I family member (sri-10) [Caenorhabditis elegans] 2.0E-55
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.1E-97
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 4.5E-8
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 5.9E-27
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492980.2 6 15-37,57-79,94-116,136-155,194-216,237-259
T22H2.1 6 15-37,57-79,94-116,136-155,194-216,237-259
SNAP00000038044 3 20-42,82-104,119-141
Sequence
Target Sequence 
>C. ELEGANS:178228_AT
agctggctggcttttgatggattcgaggtttatgattatcatttgaacaagatgatggct
gtaactggagttggagcattcgcatacgtttttataattgcatggtactgtttctacctt
ggtgtccacacaatgattattcttcaacgactccgtcaacacatgtcatctcaaaccttc
caaatgcaccgggcggctcttatcagtttagccatgcaaatggtcatccccggcgtattc
atcatagtcccattggacatttgtatgactgtagtgatcaccgagaccgtcgccttgcaa
ggtacctacctcaagctgccggttaccgatttccaagaacttacagaattcgctacggat
accatgttcatggtgggatcccattccatgtgtcagtgcagtgttatgctgttgagcaat
tccacgtatcggcgggtgttaaaggagaagatttttcgagtattgaggtctgcctgccta
catgcctacctaccaaaaaattattttttcagacttgaaataattgcaagtagtcaattg
gtcagttcagtggacccaagcatgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGCTGGCTGGCTTTTGATGGATTCG 622 79 556 Antisense
TACTGTTTCTACCTTGGTGTCCACA 504 647 661 Antisense
ACGACTCCGTCAACACATGTCATCT 435 93 702 Antisense
ATGTCATCTCAAACCTTCCAAATGC 453 47 718 Antisense
CCGGGCGGCTCTTATCAGTTTAGCC 287 263 744 Antisense
CTGTAGTGATCACCGAGACCGTCGC 659 239 824 Antisense
CAAGCTGCCGGTTACCGATTTCCAA 499 185 867 Antisense
ATGGTGGGATCCCATTCCATGTGTC 28 51 925 Antisense
GCTGTTGAGCAATTCCACGTATCGG 657 295 963 Antisense
TCGAGTATTGAGGTCTGCCTGCCTA 208 603 1011 Antisense
GTCAGTTCAGTGGACCCAAGCATGC 630 465 1096 Antisense
Sequence Source Affymetrix Proprietary Database