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[177891_s_at]

Description ZK809.2 /REP_DB=WormBase Gene ID /WP=CE03830 /TR=Q23598 /GB=CAA92638.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 58      6grp_high1_10_10 > 85      4grp_highest_8_8 > 18      4grp_high_8_8 > 62      6grp_highest_nonorm > 73      6grp_total > 74      4grp_total > 57      6grp_cgc > 66      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 460
1 2 3 4 range
A 335.9
(-1.4)
P 		526.7
(2.9)
P 		529.3
(3)
P 		264.7
(-3)
P 		265
B 367.8
(-1)
P 		515.2
(0.9)
P 		676
(3)
P 		215.9
(-3)
P 		460
C 382.1
(-1.1)
P 		492.6
(0.6)
P 		654.4
(3)
P 		252.8
(-3)
P 		402
avr 361.9
(-1.1) 		511.5
(1.3) 		619.9
(3) 		244.5
(-3) 		375

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 488
1 2 3 4 5 6 range
A 431.6
(-1.3)
P 		362
(-3)
P 		604.2
(3)
P 		448.3
(-0.9)
P 		601.7
(2.9)
P 		506.4
(0.6)
P 		242
B 339.5
(-3)
P 		444.8
(-1.3)
P 		703.9
(3)
P 		557.7
(0.6)
P 		682.5
(2.6)
P 		624.1
(1.7)
P 		364
C 229.5
(-3)
P 		591
(1.4)
P 		406.9
(-0.8)
P 		581.2
(1.3)
P 		520.1
(0.6)
P 		717.8
(3)
P 		488
avr 333.5
(-3) 		465.9
(-0.2) 		571.7
(2.1) 		529.1
(1.2) 		601.4
(2.7) 		616.1
(3) 		283
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 189
1 2 3 4 range
A 122.3
(2)
P 		114.3
(1.5)
P 		138.4
(3)
P 		38.7
(-3)
P 		100
B 117.3
(0.9)
P 		127.2
(1.4)
P 		156.6
(3)
P 		46
(-3)
P 		111
C 126.5
(-0.3)
P 		141.6
(0.2)
P 		228.1
(3)
P 		42.6
(-3)
P 		186
avr 122
(0.6) 		127.7
(0.9) 		174.4
(3) 		42.4
(-3) 		132

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 198
1 2 3 4 5 6 range
A 79.6
(-3)
P 		128.8
(-0.1)
P 		131.6
(0.1)
P 		113.7
(-1)
P 		181.6
(3)
P 		123.3
(-0.4)
P 		102
B 118.1
(-3)
P 		148
(-1.9)
P 		170.9
(-1)
P 		147.7
(-1.9)
P 		277.3
(3)
P 		232.7
(1.3)
P 		159
C 85.1
(-3)
P 		180.3
(0.7)
P 		103.6
(-2.3)
P 		116.9
(-1.8)
P 		168.3
(0.2)
P 		240.3
(3)
P 		155
avr 94.3
(-3) 		152.4
(0) 		135.4
(-0.9) 		126.1
(-1.3) 		209.1
(3) 		198.8
(2.5) 		115
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 177891_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9511
Sequence Type Exemplar sequence
Representative Public ID ZK809.2 NCBI
Target Description ZK809.2 /REP_DB=WormBase Gene ID /WP=CE03830 /TR=Q23598 /GB=CAA92638.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069801(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069801 NCBI Caenorhabditis elegans ACyLtransferase-like family member (acl-3) (acl-3) mRNA, complete cds. 11/11 None
SNAP00000011184 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11650885:11651989:-1 11/11 None
GENEFINDER00000011196 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11650885:11651989:-1 11/11 None
ZK809.2 ENSEMBL cdna:known chromosome:CEL140:IV:11650725:11651993:-1 gene:ZK809.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11650890-11651887(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol acl-3
Ensembl ZK809.2
Entrez Gene 178095 Entrez gene
SwissProt Q23598 EMBL-EBI
WormBase CE03830 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:264298_AT phospholipid/glycerol acyltransferase family protein at
CANINE:1584718_AT similar to tafazzin isoform 4 cfa
CANINE:1596823_AT similar to tafazzin isoform 4 cfa
CANINE:1584719_S_AT similar to tafazzin isoform 4 cfa
CANINE_2:CFA.4415.2.A1_AT similar to tafazzin isoform 4 cfa
CANINE_2:CFA.4415.2.A1_X_AT similar to tafazzin isoform 4 cfa
CANINE_2:CFAAFFX.29930.1.S1_S_AT similar to tafazzin isoform 4 cfa
CANINE_2:CFAAFFX.29935.1.S1_AT similar to tafazzin isoform 4 cfa
CANINE_2:CFAAFFX.29935.1.S1_S_AT similar to tafazzin isoform 4 cfa
DROSOPHILA_2:1626481_A_AT dm
DROSGENOME1:144150_AT dm
HG-U133_PLUS_2:203977_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HG-U133A:203977_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HG-U133A_2:203977_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HUGENEFL:X92762_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
U133_X3P:G4507370_3P_X_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
U133_X3P:G4507370_3P_S_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
U133_X3P:G4507370_3P_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
U133_X3P:4875649_3P_S_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
U133_X3P:37278_3P_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
U133_X3P:203977_3P_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HG-U133A_2:37278_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HG-FOCUS:37278_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HG-U133_PLUS_2:37278_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HG-U133A:37278_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HG-U95AV2:37278_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
HG-U95D:84938_R_AT Tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) hs
MOUSE430_2:1453785_AT tafazzin mm
MOE430B:1453785_AT tafazzin mm
MG-U74BV2:107572_AT tafazzin mm
MG-U74BV2:165308_F_AT tafazzin mm
MOE430A:1416207_AT tafazzin mm
MOUSE430A_2:1416207_AT tafazzin mm
MOUSE430_2:1416207_AT tafazzin mm
MU19KSUBA:TC22079_AT Tafazzin, mRNA (cDNA clone MGC:19336 IMAGE:4221041) mm
MU19KSUBB:TC31988_AT Tafazzin, mRNA (cDNA clone MGC:19336 IMAGE:4221041) mm
RG-U34C:RC_AI172122_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) rn
RAE230A:1372008_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) rn
RAT230_2:1372008_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) rn
RAE230B:1380623_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) rn
RAT230_2:1380623_AT tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome) rn
YEAST_2:1771401_AT Lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; may remodel acyl groups of cardiolipin in the inner membrane; similar to human tafazzin, which is implicated in Barth syndrome Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8415 acyltransferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92638 Hypothetical protein ZK809.2 [Caenorhabditis elegans] ref|NP_502202.1| ACyLtransferase-like family member (acl-3) [Caenorhabditis elegans] 1.0E-148
blast CAA92638 Hypothetical protein ZK809.2 [Caenorhabditis elegans] ref|NP_502202.1| ACyLtransferase-like family member (acl-3) [Caenorhabditis elegans] 1.0E-147
blast CAE62079 Hypothetical protein CBG06102 [Caenorhabditis briggsae] 1.0E-130
blast NP_001028086 tafazzin [Macaca mulatta] gb|AAT45911.1| tafazzin [Macaca mulatta] sp|Q6IV77|TAZ_MACMU Tafazzin 7.0E-60
Protein Domains
Database ID Description E-Value
Pfam IPR002123 EMBL-EBI Phospholipid/glycerol acyltransferase 9.1E-33
Pfam IPR002123 EMBL-EBI Phospholipid/glycerol acyltransferase 9.1E-33
Sequence
Target Sequence 
>C. ELEGANS:177891_S_AT
atcgctcaaatatcgacgacccgctcatgtggtgtattctgaaattccgtgagttttgga
gatacaaagatcgcaatagatacactctcgcagctcacaacatttgcttcacaaaacagt
tccatacaacaatgttctcattaggacgttgtgttccgtgtgttcgtggagaaggagttt
atcaaaaaggaatggatttctgtgtggatatgctgaatgataataaatgggttcatatct
ttccagaaggaaaagtgtgtactcttgaaagtgaaccactacgattcaagtggggaattg
gaaggcttgtgatggatgctaaaaccgatccagtaatattgcctgtatggtgtaaagaga
tggaaaaagtttggccaacacaacctccatactatcctaaatttggaaataccgtaacag
ttcacatcggagagccatttttcctgtctgatctcaagaaaacagttctatcaaagtcac
tgaccact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCGCTCAAATATCGACGACCCGCT 207 35 143 Antisense
ATCGCAATAGATACACTCTCGCAGC 454 37 212 Antisense
CTCGCAGCTCACAACATTTGCTTCA 385 233 229 Antisense
ATGTTCTCATTAGGACGTTGTGTTC 532 47 274 Antisense
GTTGTGTTCCGTGTGTTCGTGGAGA 405 437 290 Antisense
AATGGGTTCATATCTTTCCAGAAGG 541 163 368 Antisense
AAAGTTTGGCCAACACAACCTCCAT 546 121 508 Antisense
CACAACCTCCATACTATCCTAAATT 481 193 521 Antisense
GTAACAGTTCACATCGGAGAGCCAT 500 461 556 Antisense
CCATTTTTCCTGTCTGATCTCAAGA 60 271 577 Antisense
AGTTCTATCAAAGTCACTGACCACT 22 65 606 Antisense
Sequence Source Affymetrix Proprietary Database