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[177811_at] G-protein coupled receptor, srh family

Description R08H2.3 /REP_DB=WormBase Gene ID /WP=CE12598 /TR=O17986 /GB=CAB04629.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_total > 30      4grp_total > 32      6grp_cgc > 63      6grp_cgc_sub > 02      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 49
1 2 3 4 range
A 3.1
(-3)
A 		13.9
(-1.7)
A 		51.7
(3)
A 		34.8
(0.9)
A 		49
B 11.1
(-2.7)
A 		16.7
(3)
A 		10.8
(-3)
A 		14.4
(0.7)
A 		6
C 14.2
(-1.2)
A 		4.5
(-3)
A 		20.8
(0.1)
A 		36.3
(3)
A 		32
avr 9.5
(-3) 		11.7
(-2.3) 		27.8
(2.8) 		28.5
(3) 		19

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 50
1 2 3 4 5 6 range
A 5.2
(-3)
A 		33.6
(3)
A 		27.1
(1.6)
A 		12.6
(-1.4)
A 		8.7
(-2.3)
A 		5.7
(-2.9)
A 		28
B 15.8
(-1.6)
A 		19.6
(-1.2)
A 		8.7
(-2.5)
A 		52.6
(3)
A 		4.9
(-3)
A 		8.7
(-2.5)
A 		48
C 5.5
(-1)
A 		11.7
(3)
A 		4.5
(-1.7)
A 		2.5
(-3)
A 		7.9
(0.5)
A 		8.2
(0.7)
A 		9
avr 8.8
(-2.4) 		21.6
(2.6) 		13.4
(-0.6) 		22.6
(3) 		7.2
(-3) 		7.5
(-2.9) 		15
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 12
1 2 3 4 range
A 1.1
(-3)
A 		3
(-2.1)
A 		13.5
(3)
A 		5.1
(-1.1)
A 		12
B 3.5
(0.8)
A 		4.1
(3)
A 		2.5
(-3)
A 		3.1
(-0.7)
A 		2
C 4.7
(0.4)
A 		1.3
(-3)
A 		7.3
(3)
A 		6.1
(1.8)
A 		6
avr 3.1
(-2.6) 		2.8
(-3) 		7.8
(3) 		4.8
(-0.6) 		5

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 13
1 2 3 4 5 6 range
A 1
(-3)
A 		11.9
(3)
A 		5.9
(-0.3)
A 		3.2
(-1.8)
A 		2.6
(-2.1)
A 		1.4
(-2.8)
A 		11
B 5.5
(-1.2)
A 		6.5
(-0.7)
A 		2.1
(-2.9)
A 		13.9
(3)
A 		2
(-3)
A 		3.3
(-2.3)
A 		12
C 2
(-0.1)
A 		3.6
(3)
A 		1.2
(-1.6)
A 		0.5
(-3)
A 		2.6
(1.1)
A 		2.8
(1.5)
A 		3
avr 2.8
(-2.5) 		7.3
(3) 		3.1
(-2.1) 		5.9
(1.3) 		2.4
(-3) 		2.5
(-2.9) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 177811_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14272
Sequence Type Exemplar sequence
Representative Public ID R08H2.3 NCBI
Target Description R08H2.3 /REP_DB=WormBase Gene ID /WP=CE12598 /TR=O17986 /GB=CAB04629.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074422(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074422 NCBI Caenorhabditis elegans Serpentine Receptor, class H family member (srh-170) (srh-170) mRNA, complete cds. 11/11 None
SNAP00000012528 ENSEMBL cdna:SNAP chromosome:CEL140:V:15389509:15391324:-1 11/11 None
GENEFINDER00000012533 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:15389509:15391528:-1 11/11 None
R08H2.3 ENSEMBL cdna:known chromosome:CEL140:V:15389509:15391456:-1 gene:R08H2.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15389508-15391893(-) 90.1 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor, srh family
Gene Symbol srh-170
Ensembl R08H2.3
Entrez Gene 187710 Entrez gene
SwissProt O17986 EMBL-EBI
WormBase CE33156 Wormbase
Functional Annotations
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4930 G-protein coupled receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04629 Hypothetical protein R08H2.3 [Caenorhabditis elegans] ref|NP_506823.2| Serpentine Receptor, class H family member (srh-170) [Caenorhabditis elegans] 1.0E-157
blast CAB04629 Hypothetical protein R08H2.3 [Caenorhabditis elegans] ref|NP_506823.2| Serpentine Receptor, class H family member (srh-170) [Caenorhabditis elegans] 1.0E-129
blast CAB60392 Hypothetical protein Y60A3A.5 [Caenorhabditis elegans] ref|NP_507865.1| Serpentine Receptor, class H family member (srh-171) [Caenorhabditis elegans] 2.0E-79
blast CAA98445 Hypothetical protein D1054.12 [Caenorhabditis elegans] ref|NP_505760.2| Serpentine Receptor, class H family member (srh-184) [Caenorhabditis elegans] 1.0E-78
blast CAA98445 Hypothetical protein D1054.12 [Caenorhabditis elegans] ref|NP_505760.2| Serpentine Receptor, class H family member (srh-184) [Caenorhabditis elegans] 2.0E-78
Protein Domains
Database ID Description E-Value
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_506823.2 7 20-39,52-74,94-116,137-156,195-217,238-260,275-297
R08H2.3 7 20-39,52-74,94-116,137-156,195-217,238-260,275-297
SNAP00000012528 6 13-35,50-72,93-112,151-173,194-216,231-253
GENEFINDER00000012533 7 41-63,76-98,118-140,161-180,219-241,262-284,299-321
Sequence
Target Sequence 
>C. ELEGANS:177811_AT
gttggcacacttgctgtaactatcctggttgtctttgaagatcgtcattatcagattatc
aatgcactgtttggtcgaaagagaagttggtatcgacttctttacattatagttctttat
tttatttcggccacttttttggcgccagcttatttgaaaattccgaacgaaaacttggcg
aaattagttattaagaataagatcccatgtatcaccgacgacgtgctccaacgccctggc
tacttcatcatctccaccacaaacaccacgttctgcctatgcctccttttcatgctttca
atctttgcaacccaacttttttatttcgtcttttccatcttcaaccatttctctcacact
gtcgcaaaatctcgagcaacggctcgtcaacaacggaaattcgtgatcgcaatgtgcatt
caagttttcattccagtcgtcgttgtcatcatacctgtcgtttatataatctgcgcgaat
tttttcgattattacagccaggctggaaacaatcttgcaatggctgcaattgtaacacat
ggagttttaacaacatttacaatgctcattgtgcactctccttatcggaaggca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTTGGCACACTTGCTGTAACTATCC 580 435 565 Antisense
GTAACTATCCTGGTTGTCTTTGAAG 704 459 580 Antisense
GTTGGTATCGACTTCTTTACATTAT 313 437 650 Antisense
TATTTCGGCCACTTTTTTGGCGCCA 487 657 687 Antisense
ATAAGATCCCATGTATCACCGACGA 458 25 761 Antisense
TCATGCTTTCAATCTTTGCAACCCA 520 621 854 Antisense
AGCAACGGCTCGTCAACAACGGAAA 427 73 939 Antisense
GCATTCAAGTTTTCATTCCAGTCGT 693 307 980 Antisense
ATTCCAGTCGTCGTTGTCATCATAC 570 7 994 Antisense
GTTGTCATCATACCTGTCGTTTATA 698 437 1006 Antisense
TGTGCACTCTCCTTATCGGAAGGCA 699 555 1134 Antisense
Sequence Source Affymetrix Proprietary Database