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[177514_at]

Description K10C8.1 /REP_DB=WormBase Gene ID /WP=CE06167 /TR=Q21412 /GB=CAA98954.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_high1_10_10 > 88      6grp_total > 78      4grp_total > 03      6grp_high1_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 211
1 2 3 4 range
A 95.3
(-2.4)
P 		75.7
(-3)
A 		83.6
(-2.8)
A 		280.6
(3)
P 		205
B 93.1
(-2.9)
A 		91.6
(-3)
A 		100.2
(-2.5)
A 		189.3
(3)
P 		98
C 122.2
(-1.1)
P 		69.5
(-3)
A 		73.5
(-2.9)
P 		240.2
(3)
P 		171
avr 103.5
(-2.1) 		78.9
(-3) 		85.8
(-2.7) 		236.7
(3) 		158

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 141
1 2 3 4 5 6 range
A 161.2
(-0.1)
A 		114.4
(-2.6)
P 		109
(-2.8)
P 		106
(-3)
P 		145.5
(-0.9)
P 		219.3
(3)
P 		113
B 78.3
(-3)
A 		84.2
(-2.7)
P 		83.5
(-2.8)
A 		81.5
(-2.9)
P 		145.5
(-0)
P 		213.6
(3)
P 		135
C 97.1
(-3)
P 		119
(-1.7)
P 		105.1
(-2.5)
P 		123.5
(-1.5)
P 		154
(0.3)
P 		200
(3)
P 		103
avr 112.2
(-2.3) 		105.9
(-2.6) 		99.2
(-3) 		103.7
(-2.8) 		148.3
(-0.4) 		211
(3) 		112
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 25
1 2 3 4 range
A 34.7
(1.4)
P 		16.4
(-3)
A 		21.9
(-1.7)
A 		41.1
(3)
P 		25
B 29.7
(-0.6)
A 		22.6
(-3)
A 		23.2
(-2.8)
A 		40.3
(3)
P 		18
C 40.5
(3)
P 		20
(-3)
A 		25.6
(-1.4)
P 		40.5
(3)
P 		21
avr 35
(1.4) 		19.7
(-3) 		23.6
(-1.9) 		40.6
(3) 		21

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 59
1 2 3 4 5 6 range
A 29.7
(-1.8)
A 		40.7
(0.4)
P 		23.7
(-3)
P 		26.9
(-2.4)
P 		43.9
(1.1)
P 		53.4
(3)
P 		30
B 27.3
(-2.3)
A 		28
(-2.2)
P 		20.3
(-3)
A 		21.6
(-2.9)
P 		59.1
(0.9)
P 		79.6
(3)
P 		59
C 36
(-1.4)
P 		36.3
(-1.4)
P 		26.7
(-2.7)
P 		24.8
(-3)
P 		49.8
(0.6)
P 		67
(3)
P 		42
avr 31
(-2) 		35
(-1.4) 		23.6
(-3) 		24.4
(-2.9) 		50.9
(0.8) 		66.7
(3) 		43
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 177514_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.12562
Sequence Type Exemplar sequence
Representative Public ID K10C8.1 NCBI
Target Description K10C8.1 /REP_DB=WormBase Gene ID /WP=CE06167 /TR=Q21412 /GB=CAA98954.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073768(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073768 NCBI Caenorhabditis elegans K10C8.1 (K10C8.1) mRNA, complete cds. 11/11 None
SNAP00000025092 ENSEMBL cdna:SNAP chromosome:CEL140:V:12695131:12697844:-1 11/11 None
GENEFINDER00000025099 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:12695131:12697844:-1 11/11 None
K10C8.1 ENSEMBL cdna:known chromosome:CEL140:V:12695131:12697844:-1 gene:K10C8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:12695130-12697844(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl K10C8.1
Entrez Gene 187256 Entrez gene
SwissProt Q21412 EMBL-EBI
WormBase CE06167 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260593_AT CAF1 family ribonuclease at
CANINE_2:CFA.10521.1.A1_AT similar to poly(A)-specific ribonuclease (deadenylation nuclease) cfa
CANINE_2:CFA.18523.1.S1_S_AT similar to poly(A)-specific ribonuclease (deadenylation nuclease) cfa
CANINE_2:CFAAFFX.28711.1.S1_AT similar to poly(A)-specific ribonuclease (deadenylation nuclease) cfa
CHICKEN:GGAAFFX.12665.1.S1_S_AT poly(A)-specific ribonuclease (deadenylation nuclease) gga
HG-U133A:203905_AT poly(A)-specific ribonuclease (deadenylation nuclease) hs
HG-U133_PLUS_2:203905_AT poly(A)-specific ribonuclease (deadenylation nuclease) hs
HG-FOCUS:203905_AT poly(A)-specific ribonuclease (deadenylation nuclease) hs
HG-U133A_2:203905_AT poly(A)-specific ribonuclease (deadenylation nuclease) hs
HU35KSUBC:RC_AA443798_AT poly(A)-specific ribonuclease (deadenylation nuclease) hs
U133_X3P:G4505610_3P_AT poly(A)-specific ribonuclease (deadenylation nuclease) hs
HG-U95AV2:36003_AT poly(A)-specific ribonuclease (deadenylation nuclease) hs
HG-U133_PLUS_2:236801_AT Poly(A)-specific ribonuclease (deadenylation nuclease) hs
HG-U133B:236801_AT Poly(A)-specific ribonuclease (deadenylation nuclease) hs
HG-U133_PLUS_2:224112_AT Poly(A)-specific ribonuclease (deadenylation nuclease) hs
HG-U133B:224112_AT Poly(A)-specific ribonuclease (deadenylation nuclease) hs
MOE430A:1425422_A_AT poly(A)-specific ribonuclease (deadenylation nuclease) mm
MOUSE430A_2:1425422_A_AT poly(A)-specific ribonuclease (deadenylation nuclease) mm
MOUSE430_2:1425422_A_AT poly(A)-specific ribonuclease (deadenylation nuclease) mm
MG-U74AV2:160515_AT poly(A)-specific ribonuclease (deadenylation nuclease) mm
MOE430A:1437334_X_AT poly(A)-specific ribonuclease (deadenylation nuclease) mm
MOUSE430A_2:1437334_X_AT poly(A)-specific ribonuclease (deadenylation nuclease) mm
MOUSE430_2:1437334_X_AT poly(A)-specific ribonuclease (deadenylation nuclease) mm
MU19KSUBA:TC19305_AT Poly(A)-specific ribonuclease (deadenylation nuclease) (Parn), mRNA mm
MU19KSUBB:TC31699_AT Poly(A)-specific ribonuclease (deadenylation nuclease) (Parn), mRNA mm
MU19KSUBC:TC39507_AT Poly(A)-specific ribonuclease (deadenylation nuclease) (Parn), mRNA mm
RAE230B:1391608_AT Similar to Parn protein rn
RAT230_2:1391608_AT Similar to Parn protein rn
RG-U34B:RC_AI013289_AT Similar to Parn protein rn
RG-U34A:RC_AI639057_AT Similar to Parn protein rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
16481 negative regulation of transcription inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16564 transcriptional repressor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98954 Hypothetical protein K10C8.1 [Caenorhabditis elegans] ref|NP_506169.1| K10C8.1 [Caenorhabditis elegans] 0.0
blast CAE63967 Hypothetical protein CBG08556 [Caenorhabditis briggsae] 0.0
blast AAH73682 Unknown (protein for IMAGE:5572400) [Xenopus laevis] 2.0E-27
Protein Domains
Database ID Description E-Value
Pfam IPR006941 EMBL-EBI CAF1 family ribonuclease 8.2E-102
Sequence
Target Sequence 
>C. ELEGANS:177514_AT
ggattcgatagttatgtcaccggagaagtcttcttgaagcttgctcacatttatattaat
agaaggaacaacttcaagaacgaaatcttggattttgatagaatctatcaatatcttgaa
gctccgattctcaaccgtctccccttccaacttatggatgttggctgctgctacctgacc
ggtgatgattccaaaggattccgtccagatgtcattacaatagttcgaagagatcgtgtt
gcaatcgaggaggacgagttcagatatcttgagaaagcgttgggaactctcatggccacg
taccagttcgacatcgaatggtcgaaaaacaagaaggaactcttcctggccaccaattca
cctggctcatacgcattcctctgcgagaagttctcgaacgattcgagtcttgctcccctg
gatgagctggatagcggaaagaaatggaccttcgaacagcgtcaaacagc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGATTCGATAGTTATGTCACCGGAG 334 509 1141 Antisense
AGTCTTCTTGAAGCTTGCTCACATT 699 61 1167 Antisense
ATCTTGAAGCTCCGATTCTCAACCG 58 19 1253 Antisense
TCTCCCCTTCCAACTTATGGATGTT 327 611 1278 Antisense
TTATGGATGTTGGCTGCTGCTACCT 311 681 1292 Antisense
GCTGCTACCTGACCGGTGATGATTC 24 297 1307 Antisense
GGATTCCGTCCAGATGTCATTACAA 312 507 1336 Antisense
GAAAGCGTTGGGAACTCTCATGGCC 12 359 1413 Antisense
CAAGAAGGAACTCTTCCTGGCCACC 198 185 1470 Antisense
CTCATACGCATTCCTCTGCGAGAAG 230 229 1506 Antisense
GGACCTTCGAACAGCGTCAAACAGC 418 523 1586 Antisense
Sequence Source Affymetrix Proprietary Database