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[177485_s_at] man(9)-alpha-mannosidase

Description ZC506.2 /REP_DB=WormBase Gene ID /WP=CE01680 /TR=Q09642 /GB=CAA87372.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 33      6grp_high1_10_10 > 23      4grp_highest_8_8 > 43      4grp_high_8_8 > 24      6grp_highest_nonorm > 52      6grp_total > 13      4grp_total > 55      6grp_highest_sub > 02      6grp_high1_sub > 02      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 324
1 2 3 4 range
A 709.3
(3)
P 		430.6
(-3)
P 		530
(-0.9)
P 		431.7
(-3)
P 		279
B 740.3
(3)
P 		506.7
(-2.3)
P 		477
(-3)
P 		605.3
(-0.1)
P 		263
C 729.4
(3)
P 		416.2
(-3)
P 		648.3
(1.4)
P 		542.5
(-0.6)
P 		313
avr 726.3
(3) 		451.2
(-3) 		551.8
(-0.8) 		526.5
(-1.4) 		275

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 300
1 2 3 4 5 6 range
A 632.5
(0.3)
P 		711.7
(3)
P 		536.3
(-3)
P 		563.2
(-2.1)
P 		582.4
(-1.4)
P 		603.5
(-0.7)
P 		175
B 635.4
(1.6)
P 		681.5
(3)
P 		602.3
(0.6)
P 		682.9
(3)
P 		481.2
(-3)
P 		480.9
(-3)
P 		202
C 686.1
(1.1)
P 		697.8
(1.3)
P 		780.4
(3)
P 		709.3
(1.5)
P 		532.6
(-2.1)
P 		489.3
(-3)
P 		291
avr 651.3
(1.4) 		697
(3) 		639.7
(1) 		651.8
(1.4) 		532.1
(-2.7) 		524.6
(-3) 		172
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 195
1 2 3 4 range
A 258.3
(3)
P 		93.5
(-2.1)
P 		138.6
(-0.7)
P 		63.2
(-3)
P 		195
B 236.1
(3)
P 		125.1
(-2.3)
P 		110.5
(-3)
P 		129
(-2.1)
P 		126
C 241.5
(3)
P 		119.7
(-1.9)
P 		226
(2.4)
P 		91.5
(-3)
P 		150
avr 245.3
(3) 		112.8
(-2.3) 		158.4
(-0.5) 		94.6
(-3) 		151

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 138
1 2 3 4 5 6 range
A 116.6
(-3)
P 		253.1
(3)
P 		116.8
(-3)
P 		142.8
(-1.8)
P 		175.7
(-0.4)
P 		146.9
(-1.7)
P 		137
B 221.1
(2.6)
P 		226.8
(3)
P 		146.3
(-3)
P 		180.9
(-0.4)
P 		195.5
(0.7)
P 		179.3
(-0.5)
P 		81
C 254.3
(3)
P 		212.9
(0.8)
P 		198.6
(0)
P 		142.7
(-3)
P 		172.3
(-1.4)
P 		163.8
(-1.9)
P 		112
avr 197.3
(0.4) 		230.9
(3) 		153.9
(-3) 		155.5
(-2.9) 		181.2
(-0.9) 		163.3
(-2.3) 		77
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 177485_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16137
Sequence Type Exemplar sequence
Representative Public ID ZC506.2 NCBI
Target Description ZC506.2 /REP_DB=WormBase Gene ID /WP=CE01680 /TR=Q09642 /GB=CAA87372.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077270(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077270 NCBI Caenorhabditis elegans ZC506.1 (man(9)-alpha-mannosidase) mRNA, complete cds. 9/11 A 
GENEFINDER00000023348 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:9958966:9964246:1 9/11 None
SNAP00000023344 ENSEMBL cdna:SNAP chromosome:CEL140:X:9962523:9964246:1 9/11 None
ZC506.1 ENSEMBL cdna:known chromosome:CEL140:X:9958892:9964665:1 gene:ZC506.1 9/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:9962265-9964246(+) 100.0 100.0
Public Domain and Genome References
Gene Title man(9)-alpha-mannosidase
Ensembl ZC506.1
Entrez Gene 181210 Entrez gene
SwissProt Q09641 EMBL-EBI
WormBase CE37461 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.20827.1.S1_AT similar to Putative alpha-mannosidase C1orf22 cfa
DROSOPHILA_2:1630203_AT dm
DROSGENOME1:146315_AT dm
CHICKEN:GGA.10298.1.S1_S_AT similar to Putative alpha-mannosidase C1orf22 gga
CHICKEN:GGAAFFX.26310.1.S1_AT similar to Putative alpha-mannosidase C1orf22 gga
HG-U133_PLUS_2:220342_X_AT chromosome 1 open reading frame 22 hs
HG-U133A:220342_X_AT chromosome 1 open reading frame 22 hs
HG-U133A_2:220342_X_AT chromosome 1 open reading frame 22 hs
HU35KSUBA:RC_AA256323_AT chromosome 1 open reading frame 22 hs
HU35KSUBB:RC_AA179387_AT chromosome 1 open reading frame 22 hs
HG-U133A:220926_S_AT chromosome 1 open reading frame 22 hs
HG-U133_PLUS_2:220926_S_AT chromosome 1 open reading frame 22 hs
HG-U133A_2:220926_S_AT chromosome 1 open reading frame 22 hs
U133_X3P:G8922223_3P_S_AT chromosome 1 open reading frame 22 hs
U133_X3P:G13376781_3P_S_AT chromosome 1 open reading frame 22 hs
U133_X3P:HS.301997.1.S1_3P_S_AT chromosome 1 open reading frame 22 hs
HG-U133_PLUS_2:223243_S_AT chromosome 1 open reading frame 22 hs
HG-U133B:223243_S_AT chromosome 1 open reading frame 22 hs
HG-U95B:59633_AT chromosome 1 open reading frame 22 hs
HG-U95C:65608_AT chromosome 1 open reading frame 22 hs
HG-U95E:90857_AT chromosome 1 open reading frame 22 hs
HG-U95C:56528_R_AT Chromosome 1 open reading frame 22 hs
MG-U74AV2:104114_AT RIKEN cDNA 2310050N11 gene mm
MOE430A:1460401_AT RIKEN cDNA 2310050N11 gene mm
MOUSE430A_2:1460401_AT RIKEN cDNA 2310050N11 gene mm
MOUSE430_2:1460401_AT RIKEN cDNA 2310050N11 gene mm
MG-U74BV2:105544_AT RIKEN cDNA 2310050N11 gene, mRNA (cDNA clone IMAGE:3984921) mm
MG-U74BV2:110546_AT RIKEN cDNA 2310050N11 gene, mRNA (cDNA clone IMAGE:3984921) mm
MOE430B:1459133_AT RIKEN cDNA 2310050N11 gene, mRNA (cDNA clone IMAGE:3984921) mm
MOUSE430_2:1459133_AT RIKEN cDNA 2310050N11 gene, mRNA (cDNA clone IMAGE:3984921) mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6487 protein amino acid N-linked glycosylation inferred from electronic annotation QuickGO AmiGO
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity inferred from electronic annotation QuickGO AmiGO
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
8233 peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA87371 Hypothetical protein ZC506.1 [Caenorhabditis elegans] ref|NP_509671.3| ZC506.1 [Caenorhabditis elegans] 0.0
blast CAE58760 Hypothetical protein CBG01952 [Caenorhabditis briggsae] 0.0
blast XP_193956 PREDICTED: hypothetical protein LOC66967 [Mus musculus] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001382 EMBL-EBI Glycoside hydrolase, family 47 1.0E-126
Pfam IPR003137 EMBL-EBI Protease-associated PA 1.6E-29
Pfam IPR003137 EMBL-EBI Protease-associated PA 1.6E-29
Sequence
Target Sequence 
>C. ELEGANS:177485_S_AT
atcccatccatatttttgttccgtgctgaaggggaccacttgttacgttctttgaaaatg
cattccgaaacggtcatttcgatatcatctcatcacctctcgattggtaagttaaaaaac
atggacttgacttcgaacttaaatatttcagaaaacacaattggtcggcttttgcgatat
ggcaaaatgttcaagtttcctgaatacccacaatgttcactcagagacggtgatattata
ttgcacaatttggattatcctgaagttattctcaatctgcgtttcaatggtattaatcaa
gatagtgatccaagactacatcaagaaattgttgagcgtcacgtcacagaactacaaaaa
tatctagagttcaaggatgctgactatgcgttccagttttatgagttcttccgtacggca
gcatatggagcacttgatttgaatgtggaaaatagtaagctgctcacagtaatttctgca
ctgagtacgttaaaaacaaaaccaattccaccatcagtttttgcgagacttcccggagag
attac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCCCATCCATATTTTTGTTCCGTG 525 37 568 Antisense
TGTTCCGTGCTGAAGGGGACCACTT 463 555 584 Antisense
TGAAGGGGACCACTTGTTACGTTCT 361 545 594 Antisense
GGTCATTTCGATATCATCTCATCAC 668 503 639 Antisense
CATCTCATCACCTCTCGATTGGTAA 81 213 653 Antisense
AACATGGACTTGACTTCGAACTTAA 318 137 685 Antisense
ATTGGTCGGCTTTTGCGATATGGCA 281 3 727 Antisense
AAGTTTCCTGAATACCCACAATGTT 250 157 760 Antisense
CCCACAATGTTCACTCAGAGACGGT 597 257 774 Antisense
AGTTATTCTCAATCTGCGTTTCAAT 183 63 831 Antisense
TTGCGAGACTTCCCGGAGAGATTAC 157 701 1088 Antisense
Sequence Source Affymetrix Proprietary Database