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[177185_s_at]

Description Y73B6BL.V /REP_DB=WormBase Gene ID /WP=CE26294 /CHR=4 /FEA=Sanger Annotation /DEF=(ST.LOUIS) protein_id:AAG23480.1
Cluster 6grp_total > 54      4grp_total > 32      6grp_cgc > 91      6grp_cgc_sub > 03      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 57
1 2 3 4 range
A 18.7
(-3)
A 		35.6
(-0.8)
A 		39.6
(-0.3)
A 		65.4
(3)
A 		47
B 53.6
(0.4)
A 		73.1
(2.6)
A 		76.1
(3)
A 		24.9
(-3)
A 		51
C 41.3
(-0.9)
A 		28.8
(-3)
A 		41.2
(-0.9)
A 		63.9
(3)
A 		35
avr 37.9
(-3) 		45.8
(0.3) 		52.3
(3) 		51.4
(2.6) 		14

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 52
1 2 3 4 5 6 range
A 4.8
(-3)
A 		21.5
(-0.3)
A 		41.4
(3)
A 		25.3
(0.4)
A 		8.9
(-2.3)
A 		25.6
(0.4)
A 		37
B 35.9
(-0.2)
A 		48.1
(3)
A 		47.8
(2.9)
A 		43.4
(1.8)
A 		39.7
(0.8)
A 		25.5
(-3)
A 		23
C 41.6
(1.4)
A 		39.7
(1.2)
A 		55.5
(3)
A 		3.6
(-3)
A 		30.6
(0.1)
A 		35.7
(0.7)
A 		52
avr 27.4
(-2.2) 		36.4
(0.1) 		48.2
(3) 		24.1
(-3) 		26.4
(-2.4) 		28.9
(-1.8) 		24
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 6.8
(-3)
A 		7.7
(-1.5)
A 		10.4
(3)
A 		9.6
(1.7)
A 		4
B 17.1
(2.5)
A 		18.1
(3)
A 		17.6
(2.8)
A 		5.3
(-3)
A 		13
C 13.7
(2.4)
A 		8.3
(-3)
A 		14.3
(3)
A 		10.8
(-0.5)
A 		6
avr 12.5
(1.3) 		11.4
(0.1) 		14.1
(3) 		8.6
(-3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 15
1 2 3 4 5 6 range
A 0.9
(-3)
A 		7.6
(2)
A 		9
(3)
A 		6.4
(1.1)
A 		2.7
(-1.7)
A 		6.2
(0.9)
A 		8
B 12.5
(-0.3)
A 		16
(2.9)
A 		11.6
(-1.1)
A 		11.5
(-1.2)
A 		16.1
(3)
A 		9.5
(-3)
A 		7
C 15.4
(3)
A 		12.1
(1.7)
A 		14.1
(2.5)
A 		0.7
(-3)
A 		9.9
(0.8)
A 		11.9
(1.6)
A 		15
avr 9.6
(0.6) 		11.9
(3) 		11.6
(2.7) 		6.2
(-3) 		9.6
(0.6) 		9.2
(0.2) 		6
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 177185_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19331
Sequence Type Exemplar sequence
Representative Public ID Y73B6BL.V NCBI
Target Description Y73B6BL.V /REP_DB=WormBase Gene ID /WP=CE26294 /CHR=4 /FEA=Sanger Annotation /DEF=(ST.LOUIS) protein_id:AAG23480.1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028404(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001028404 NCBI Caenorhabditis elegans CaSPase family member (csp-2) (csp-2) mRNA, complete cds. 11/11 None
GENEFINDER00000032093 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:6307723:6316193:1 11/11 None
Y73B6BL.7 ENSEMBL cdna:known chromosome:CEL140:IV:6307723:6315703:1 gene:Y73B6BL.7 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_001026683 2/11 Cross Hyb Matching Probes None
NM_001026684 2/11 Cross Hyb Matching Probes None
NM_001026688 2/11 Cross Hyb Matching Probes None
SNAP00000012416 2/11 Cross Hyb Matching Probes None
GENEFINDER00000012421 2/11 Cross Hyb Matching Probes None
SNAP00000032030 5/11 Cross Hyb Matching Probes None
ZK1151.1b 2/11 Cross Hyb Matching Probes A 
ZK1151.1c 2/11 Cross Hyb Matching Probes A 
ZK1151.1g 2/11 Cross Hyb Matching Probes A 
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:6307728-6310081(+) 99.15 100.0
Public Domain and Genome References
Gene Title
Gene Symbol csp-2
Ensembl Y73B6BL.7
Entrez Gene 177391 Entrez gene
SwissProt Q9Y055 EMBL-EBI
WormBase CE28270 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
30693 caspase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAM44398 Caspase protein 2 [Caenorhabditis elegans] ref|NP_001023575.1| CaSPase family member (csp-2) [Caenorhabditis elegans] gb|AAC98295.1| caspase-related protein 2A [Caenorhabditis elegans] 0.0
blast CAD44516 VAB-10B protein [Caenorhabditis elegans] 1.0E-148
blast CAH04759 Hypothetical protein ZK1151.1g [Caenorhabditis elegans] emb|CAH04743.1| Hypothetical protein ZK1151.1g [Caenorhabditis elegans] emb|CAH04711.1| Hypothetical protein ZK1151.1g [Caenorhabditis elegans] ref|NP_001021859.1| Variable ABnormal morphology family member (vab-10) [Caenorhabditis elegans] 1.0E-148
Protein Domains
Database ID Description E-Value
Pfam IPR001309 EMBL-EBI Caspase-1, p20 2.8E-81
Pfam IPR004296 EMBL-EBI Protein of unknown function DUF236 4.3E-6
Pfam IPR001309 EMBL-EBI Caspase-1, p20 2.5E-71
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001023575.1 1 37-59
Y73B6BL.7 1 37-59
GENEFINDER00000032093 1 37-59
Sequence
Target Sequence 
>C. ELEGANS:177185_S_AT
ctcactcatcgccttatcagaatgcaaatgaatctgctattgacgatgcctacttcctcg
ttttgatcatcccggcagtctcggttgcgattgttctagttgtcgttatcttcttgtgtt
gtccaagacaacaaattcggagcgacaatgtcataaaattggaagaaggtgttaatgatg
tgattgaggaaaatgtgacacacgttgtatcgctccgtgaagctaaggtgtctggcatga
tgacggacttgacgaggttccgacaggagattttcacgaaacatctcacgttcaactcga
atccagagtcaattgatgcggcgacgaagaatgttcagaacgtgaaacagtctctggaca
cgtggcgtgaccgaatcaaggagcgattggacgagattgatcggctttgcactgaagaag
gcgactcgttgacaccggagcagtata

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTCACTCATCGCCTTATCAGAATGC 696 227 74 Antisense
GAATCTGCTATTGACGATGCCTACT 326 329 103 Antisense
GCAGTCTCGGTTGCGATTGTTCTAG 185 309 148 Antisense
TTGTCGTTATCTTCTTGTGTTGTCC 697 707 173 Antisense
GACACACGTTGTATCGCTCCGTGAA 17 367 270 Antisense
GCTCCGTGAAGCTAAGGTGTCTGGC 387 297 285 Antisense
GACTTGACGAGGTTCCGACAGGAGA 520 371 319 Antisense
AACATCTCACGTTCAACTCGAATCC 536 137 353 Antisense
GAAACAGTCTCTGGACACGTGGCGT 696 355 417 Antisense
CGAGATTGATCGGCTTTGCACTGAA 683 249 465 Antisense
GACTCGTTGACACCGGAGCAGTATA 223 373 496 Antisense
Sequence Source Affymetrix Proprietary Database