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[176888_at]

Description Y73E7A.E /REP_DB=WormBase Gene ID /WP=CE26415 /CHR=1 /FEA=Sanger Annotation /DEF=(ST.LOUIS) protein_id:AAG23387.1
Cluster 6grp_highest_10_10 > 50      6grp_high1_10_10 > 06      4grp_high_8_8 > 16      6grp_highest_nonorm > 60      6grp_total > 06      4grp_total > 31      6grp_highest_sub > De      6grp_cgc > 21      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 392
1 2 3 4 range
A 557.6
(3)
P 		314.8
(-1.7)
P 		249.4
(-3)
M 		480.7
(1.5)
P 		308
B 641.2
(3)
P 		285.6
(-2.7)
P 		265
(-3)
P 		364.1
(-1.4)
P 		376
C 631.1
(3)
P 		284.9
(-2.7)
P 		267.8
(-3)
P 		401.3
(-0.8)
P 		363
avr 610
(3) 		295.1
(-2.4) 		260.7
(-3) 		415.4
(-0.3) 		349

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 578
1 2 3 4 5 6 range
A 453.6
(1.7)
P 		520.1
(3)
P 		412.6
(0.8)
P 		339.9
(-0.6)
P 		221.5
(-3)
P 		295.5
(-1.5)
P 		299
B 510.2
(3)
P 		350.1
(-0.3)
P 		333.4
(-0.7)
P 		223.3
(-3)
P 		297.8
(-1.4)
P 		248
(-2.5)
P 		287
C 773.1
(3)
P 		386.8
(-1)
P 		416.5
(-0.7)
P 		247.3
(-2.5)
P 		275.9
(-2.2)
P 		195.1
(-3)
P 		578
avr 579
(3) 		419
(0.1) 		387.5
(-0.5) 		270.2
(-2.6) 		265.1
(-2.7) 		246.2
(-3) 		333
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 148
1 2 3 4 range
A 203
(3)
P 		68.3
(-2.9)
P 		65.2
(-3)
M 		70.4
(-2.8)
P 		138
B 204.5
(3)
P 		70.5
(-2.6)
P 		61.4
(-3)
P 		77.6
(-2.3)
P 		143
C 208.9
(3)
P 		81.9
(-2.4)
P 		93.3
(-1.9)
P 		67.7
(-3)
P 		141
avr 205.5
(3) 		73.6
(-2.9) 		73.3
(-2.9) 		71.9
(-3) 		134

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 237
1 2 3 4 5 6 range
A 83.6
(-2.1)
P 		185
(3)
P 		89.9
(-1.8)
P 		86.2
(-2)
P 		66.8
(-3)
P 		72
(-2.7)
P 		118
B 177.5
(3)
P 		116.5
(-0.1)
P 		81
(-1.9)
P 		59.1
(-3)
P 		121
(0.1)
P 		92.5
(-1.3)
P 		118
C 286.5
(3)
P 		118
(-1.3)
P 		106
(-1.6)
P 		49.7
(-3)
P 		89.3
(-2)
P 		65.3
(-2.6)
P 		237
avr 182.5
(3) 		139.8
(0.8) 		92.3
(-1.6) 		65
(-3) 		92.4
(-1.6) 		76.6
(-2.4) 		118
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 176888_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18654
Sequence Type Exemplar sequence
Representative Public ID Y73E7A.E NCBI
Target Description Y73E7A.E /REP_DB=WormBase Gene ID /WP=CE26415 /CHR=1 /FEA=Sanger Annotation /DEF=(ST.LOUIS) protein_id:AAG23387.1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058467(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058467 NCBI Caenorhabditis elegans Y73E7A.4 (Y73E7A.4) mRNA, complete cds. 11/11 None
SNAP00000005637 ENSEMBL cdna:SNAP chromosome:CEL140:I:1594981:1596176:-1 11/11 None
GENEFINDER00000005648 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:1594981:1596176:-1 11/11 None
Y73E7A.4 ENSEMBL cdna:known chromosome:CEL140:I:1594671:1596176:-1 gene:Y73E7A.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:1594980-1596176(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol cpx-1
Ensembl Y73E7A.4
Entrez Gene 190666 Entrez gene
SwissProt Q9GUM7 EMBL-EBI
WormBase CE26415 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1636880_S_AT dm
DROSOPHILA_2:1639609_S_AT dm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6836 neurotransmitter transport inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
19905 syntaxin binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAG23387 Hypothetical protein Y73E7A.4 [Caenorhabditis elegans] ref|NP_490868.1| Y73E7A.4 [Caenorhabditis elegans] 3.0E-60
blast CAE74424 Hypothetical protein CBG22157 [Caenorhabditis briggsae] 4.0E-59
blast AAW27309 SJCHGC05979 protein [Schistosoma japonicum] 8.0E-17
Protein Domains
Database ID Description E-Value
Pfam IPR008849 EMBL-EBI Synaphin 2.6E-83
Sequence
Target Sequence 
>C. ELEGANS:176888_AT
aaatcagctgagcgaggtgaccggcggtctcggtatgaaggacgatggtggtgagaagac
ggaaactggagaggatccagaagtgattgcggctcggttggagcaagaggaacggcgtaa
ggagaagcatcggaagatggagaatgagagagaaaaaatgcgtcagggcattcgtgataa
gtatgctattaagaagaaggaagagggtgttgctatggattttactgaaggacgtattgg
aggaccccgcaagactccggaggagatcgccgctgaaatgaacgctgaggacgacagtct
catcggccaactcgggctcacggagcaagtcgaaaaagcgaaaactatggcgaccggcgc
cttc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAATCAGCTGAGCGAGGTGACCGGC 61 115 45 Antisense
GTGACCGGCGGTCTCGGTATGAAGG 262 465 61 Antisense
GAAGTGATTGCGGCTCGGTTGGAGC 370 335 124 Antisense
TGCGTCAGGGCATTCGTGATAAGTA 494 583 203 Antisense
GGGTGTTGCTATGGATTTTACTGAA 58 499 249 Antisense
TGAAGGACGTATTGGAGGACCCCGC 628 567 270 Antisense
GTATTGGAGGACCCCGCAAGACTCC 215 451 278 Antisense
GCAAGACTCCGGAGGAGATCGCCGC 458 321 293 Antisense
GATCGCCGCTGAAATGAACGCTGAG 443 417 309 Antisense
GCTGAGGACGACAGTCTCATCGGCC 438 295 328 Antisense
GAAAACTATGGCGACCGGCGCCTTC 166 355 384 Antisense
Sequence Source Affymetrix Proprietary Database