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[176851_at]

Description Y40B10A.6 /REP_DB=WormBase Gene ID /WP=CE21794 /GB=AAK70661.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation
Cluster 4grp_high_8_8 > 28      6grp_total > 87      4grp_total > 36      6grp_total_sub > Increase      6grp_rule_based > S6      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 124
1 2 3 4 range
A 174.4
(-1.6)
P 		216.9
(3)
A 		161.4
(-3)
A 		211.2
(2.4)
P 		56
B 249.7
(3)
P 		231.1
(1.8)
A 		159.9
(-3)
P 		180.7
(-1.6)
P 		90
C 149.6
(-2)
P 		253.1
(3)
P 		128.9
(-3)
P 		249.3
(2.8)
P 		124
avr 191.2
(-0.1) 		233.7
(3) 		150.1
(-3) 		213.7
(1.6) 		84

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 262
1 2 3 4 5 6 range
A 109.5
(-3)
A 		117.1
(-2.8)
P 		112.9
(-2.9)
A 		192
(-1.1)
P 		251.7
(0.3)
P 		366.5
(3)
P 		257
B 128.8
(-2.4)
M 		138.5
(-2.1)
P 		104.3
(-3)
A 		148.1
(-1.9)
P 		231.6
(0.3)
P 		337.9
(3)
P 		234
C 132.5
(-2.6)
P 		169.2
(-1.4)
P 		162.2
(-1.6)
A 		119.9
(-3)
M 		191.4
(-0.7)
P 		303.8
(3)
P 		184
avr 123.6
(-3) 		141.6
(-2.5) 		126.5
(-2.9) 		153.3
(-2.2) 		224.9
(-0.1) 		336.1
(3) 		213
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 49
1 2 3 4 range
A 63.5
(3)
P 		47.1
(-0)
A 		42.2
(-0.9)
A 		30.9
(-3)
P 		33
B 79.6
(3)
P 		57.1
(-0.2)
A 		37.1
(-3)
P 		38.5
(-2.8)
P 		43
C 49.5
(-1.5)
P 		72.8
(3)
P 		44.9
(-2.4)
P 		42
(-3)
P 		31
avr 64.2
(3) 		59
(1.8) 		41.4
(-2) 		37.1
(-3) 		27

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 106
1 2 3 4 5 6 range
A 20.2
(-3)
A 		41.6
(-1.1)
P 		24.6
(-2.6)
A 		48.7
(-0.5)
P 		75.9
(1.8)
P 		89.2
(3)
P 		69
B 44.8
(-1.8)
M 		46.1
(-1.8)
P 		25.3
(-3)
A 		39.2
(-2.2)
P 		94.1
(1.1)
P 		126
(3)
P 		101
C 49.1
(-1.1)
P 		51.6
(-0.9)
P 		41.3
(-1.7)
A 		24.1
(-3)
M 		61.9
(-0.1)
P 		101.7
(3)
P 		78
avr 38
(-2.4) 		46.4
(-1.7) 		30.4
(-3) 		37.3
(-2.4) 		77.3
(0.7) 		105.6
(3) 		75
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 176851_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15437
Sequence Type Exemplar sequence
Representative Public ID Y40B10A.6 NCBI
Target Description Y40B10A.6 /REP_DB=WormBase Gene ID /WP=CE21794 /GB=AAK70661.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_071157(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_071157 NCBI Caenorhabditis elegans Y40B10A.6 (Y40B10A.6) mRNA, complete cds. 11/11 None
SNAP00000009375 ENSEMBL cdna:SNAP chromosome:CEL140:V:2049163:2050000:-1 11/11 None
GENEFINDER00000009385 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:2049163:2050000:-1 11/11 None
Y40B10A.6 ENSEMBL cdna:known chromosome:CEL140:V:2049163:2050000:-1 gene:Y40B10A.6 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_071158 1/11 Cross Hyb Matching Probes None
SNAP00000009377 1/11 Cross Hyb Matching Probes None
GENEFINDER00000009386 1/11 Cross Hyb Matching Probes None
Y40B10A.7 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:2049162-2050000(-) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl Y40B10A.6
Entrez Gene 189789 Entrez gene
SwissProt Q965W4 EMBL-EBI
WormBase CE21794 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:251295_AT O-methyltransferase family 3 protein at
CANINE_2:CFAAFFX.23671.1.S1_AT similar to catechol-O-methyltransferase domain containing 1 cfa
CHICKEN:GGAAFFX.3113.1.S1_AT similar to catechol-O-methyltransferase domain containing 1 gga
HU35KSUBC:RC_AA279840_AT catechol-O-methyltransferase domain containing 1 hs
U133_X3P:HS.111110.1.S1_3P_AT catechol-O-methyltransferase domain containing 1 hs
HG-U133_PLUS_2:226870_AT catechol-O-methyltransferase domain containing 1 hs
HG-U133B:226870_AT catechol-O-methyltransferase domain containing 1 hs
HG-U95B:43063_AT catechol-O-methyltransferase domain containing 1 hs
HG-U95B:43354_AT catechol-O-methyltransferase domain containing 1 hs
MOUSE430_2:1428635_AT catechol-O-methyltransferase domain containing 1 mm
MOE430A:1428635_AT catechol-O-methyltransferase domain containing 1 mm
MOUSE430A_2:1428635_AT catechol-O-methyltransferase domain containing 1 mm
MG-U74AV2:160590_R_AT catechol-O-methyltransferase domain containing 1 mm
MU19KSUBA:TC15266_AT Full open reading frame cDNA clone RZPDo836E0753D for gene Comtd1, Catechol-O-methyltransferase domain containing 1; complete cds, incl. stopcodon mm
MU19KSUBA:TC20686_AT Full open reading frame cDNA clone RZPDo836E0753D for gene Comtd1, Catechol-O-methyltransferase domain containing 1; complete cds, incl. stopcodon mm
RG-U34B:RC_AA943314_AT catechol-O-methyltransferase domain containing 1 (predicted) rn
RG-U34B:RC_AA899498_AT catechol-O-methyltransferase domain containing 1 (predicted) rn
RG-U34B:RC_AA899498_G_AT catechol-O-methyltransferase domain containing 1 (predicted) rn
RAE230A:1373150_AT catechol-O-methyltransferase domain containing 1 (predicted) rn
RAT230_2:1373150_AT catechol-O-methyltransferase domain containing 1 (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
8171 O-methyltransferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK70661 Hypothetical protein Y40B10A.6 [Caenorhabditis elegans] ref|NP_503558.1| Y40B10A.6 [Caenorhabditis elegans] 1.0E-129
blast AAK70662 Hypothetical protein Y40B10A.7 [Caenorhabditis elegans] ref|NP_503559.2| Y40B10A.7 [Caenorhabditis elegans] 1.0E-107
blast CAE66789 Hypothetical protein CBG12149 [Caenorhabditis briggsae] 1.0E-107
Protein Domains
Database ID Description E-Value
Pfam IPR002935 EMBL-EBI O-methyltransferase, family 3 8.8E-13
Pfam IPR002935 EMBL-EBI O-methyltransferase, family 3 8.2E-39
Sequence
Target Sequence 
>C. ELEGANS:176851_AT
aaaaggagacgctcaccaacgctccacactctggaatgctaggagctcctgaagttctta
catttggagagaactttataaaattcttaggtgcaaagcgtgtacttgatgttggaacat
tcaccggagcatctgctttagcctgggctctcgctgtcccggatgatggagaagttttca
cttttgacatcgaccatgccaattatcgcaagttcggagttccaatcctatcaaaatgcg
agaaaactttcaagaagatcaagccagtggaaggcccaggggttgagagtctagacaaac
taatcgccgacggacaatccggaacctttgattttgcattcatcgatgctgataaggcga
attatagtaactactatgagaaatgtgtttccctactccgcaagggaggtgtcatttttg
tggataatagtctctgggacggagcagtttgcgatcctgccaagagaaccgatccacgta
ccgctgcgattcacgagat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAAGGAGACGCTCACCAACGCTCC 185 129 113 Antisense
AACGCTCCACACTCTGGAATGCTAG 35 147 130 Antisense
GGAGCTCCTGAAGTTCTTACATTTG 327 521 154 Antisense
TCACCGGAGCATCTGCTTTAGCCTG 595 625 233 Antisense
GAAGTTTTCACTTTTGACATCGACC 117 335 283 Antisense
GACATCGACCATGCCAATTATCGCA 139 369 298 Antisense
GCAAGTTCGGAGTTCCAATCCTATC 152 321 320 Antisense
AGGCCCAGGGGTTGAGAGTCTAGAC 346 1 384 Antisense
GACGGAGCAGTTTGCGATCCTGCCA 238 377 550 Antisense
TGCCAAGAGAACCGATCCACGTACC 442 585 570 Antisense
CACGTACCGCTGCGATTCACGAGAT 207 199 587 Antisense
Sequence Source Affymetrix Proprietary Database