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[176768_at]

Description C07F11.1 /REP_DB=WormBase Gene ID /WP=CE23527 /GB=AAF39752.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation
Cluster 6grp_highest_10_10 > 81      6grp_high1_10_10 > 29      4grp_highest_8_8 > 57      4grp_high_8_8 > 33      6grp_highest_nonorm > 80      6grp_total > 28      4grp_total > 46      6grp_highest_sub > Cu      6grp_cgc > 03      6grp_high1_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 178
1 2 3 4 range
A 284.9
(3)
P 		173.9
(-1)
P 		117.8
(-3)
P 		131.4
(-2.5)
P 		167
B 288.3
(3)
P 		157.7
(-1.5)
P 		135.5
(-2.3)
P 		114
(-3)
P 		174
C 235.3
(3)
P 		170.9
(-0.1)
P 		124.1
(-2.3)
P 		110.5
(-3)
P 		125
avr 269.5
(3) 		167.5
(-1.1) 		125.8
(-2.7) 		118.6
(-3) 		151

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 214
1 2 3 4 5 6 range
A 273.4
(3)
P 		222.9
(0.6)
P 		148
(-3)
P 		197.2
(-0.6)
P 		246.5
(1.7)
P 		212.5
(0.1)
P 		125
B 232.9
(2.3)
P 		245.9
(3)
P 		130.8
(-3)
P 		160.1
(-1.5)
P 		176.8
(-0.6)
P 		205.1
(0.9)
P 		115
C 344.9
(3)
P 		264.3
(0.3)
P 		183.8
(-2.5)
P 		188.8
(-2.3)
P 		187.8
(-2.3)
P 		168.3
(-3)
P 		177
avr 283.7
(3) 		244.4
(1.2) 		154.2
(-3) 		182
(-1.7) 		203.7
(-0.7) 		195.3
(-1.1) 		130
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 85
1 2 3 4 range
A 103.7
(3)
P 		37.8
(-1.7)
P 		30.8
(-2.2)
P 		19.2
(-3)
P 		85
B 91.9
(3)
P 		38.9
(-1.7)
P 		31.4
(-2.4)
P 		24.3
(-3)
P 		68
C 77.9
(3)
P 		49.1
(0.1)
P 		43.2
(-0.5)
P 		18.6
(-3)
P 		59
avr 91.2
(3) 		41.9
(-1.2) 		35.1
(-1.8) 		20.7
(-3) 		71

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 96
1 2 3 4 5 6 range
A 50.4
(-0.7)
P 		79.3
(3)
P 		32.2
(-3)
P 		50
(-0.7)
P 		74.4
(2.4)
P 		51.7
(-0.5)
P 		47
B 81
(2.9)
P 		81.9
(3)
P 		31.8
(-3)
P 		42.4
(-1.7)
P 		71.8
(1.8)
P 		76.5
(2.4)
P 		50
C 127.8
(3)
P 		80.7
(-0.1)
P 		46.8
(-2.4)
P 		38
(-3)
P 		60.8
(-1.5)
P 		56.3
(-1.8)
P 		90
avr 86.4
(3) 		80.6
(2.3) 		36.9
(-3) 		43.5
(-2.2) 		69
(0.9) 		61.5
(-0) 		50
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 176768_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2572
Sequence Type Exemplar sequence
Representative Public ID C07F11.1 NCBI
Target Description C07F11.1 /REP_DB=WormBase Gene ID /WP=CE23527 /GB=AAF39752.1 /SUBMIT=ST.LOUIS /CHR=1 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001025812(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001025812 NCBI Caenorhabditis elegans TOLl (Drosophila) family member (tol-1) (tol-1) mRNA, complete cds. 11/11 None
C07F11.1 ENSEMBL cdna:known chromosome:CEL140:I:444002:461590:1 gene:C07F11.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:444020-458748(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol tol-1
Ensembl C07F11.1
Entrez Gene 171635 Entrez gene
SwissProt Q9N5Z3 EMBL-EBI
WormBase CE28818 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1624790_AT Toll-6 dm
DROSGENOME1:153641_AT Toll-6 dm
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
5623 cell inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
5057 receptor signaling protein activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF39752 Toll (drosophila) family protein 1 [Caenorhabditis elegans] ref|NP_001020983.1| TOLl (Drosophila) family member (tol-1) [Caenorhabditis elegans] 0.0
blast AAK37544 Toll-like receptor TOL-1 [Caenorhabditis elegans] 0.0
blast CAE74340 Hypothetical protein CBG22058 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.48
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.13
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.023
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.0038
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.07
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.045
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.49
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.0063
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.012
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.034
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.95
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.022
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.034
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.39
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.02
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001020983.1 1 999-1021
C07F11.1 1 999-1021
Sequence
Target Sequence 
>C. ELEGANS:176768_AT
gagatcattctgagcggagtcacccttccacagctccgaactcacagcttcatcggaaga
cttcgtctccagaggcttcatatcaatggaaccgggctccgatccatccaaccgaaggct
ttccatactcttccagcactgaagacgctggatttgtcggataactcgttgatctcgctg
agcggggaggaatttctaaagtgtggagaagtctcgcagcttttcctcaatggaaatcga
ttttccacgctatcccgtggaatcttcgagaagcttccgaacttgaaatatctgacactt
cataacaactccctcgaagacatccctcaggttcttcactcgacggcgctctccaagatc
tccctgtcatcgaaccccttgagatgcgactgctcgggaggatcccaacagcaccttcac
catcgtcgtgacccaaaagctcatccattctgggagcataatgcggccgagtggttctcg
ttgcatcggcatcttgtcgttgatttccccaaggttgaatgctgggagaacgtgacgaag
gccttcctgacgaacgatacgacagtgctgagcgccta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGATCATTCTGAGCGGAGTCACCC 260 397 2302 Antisense
CTTCGTCTCCAGAGGCTTCATATCA 67 221 2362 Antisense
CAACCGAAGGCTTTCCATACTCTTC 46 187 2410 Antisense
GTCGGATAACTCGTTGATCTCGCTG 507 471 2457 Antisense
TCATAACAACTCCCTCGAAGACATC 175 621 2601 Antisense
GAAGACATCCCTCAGGTTCTTCACT 667 337 2617 Antisense
GTCATCGAACCCCTTGAGATGCGAC 655 465 2667 Antisense
GAGATGCGACTGCTCGGGAGGATCC 353 395 2682 Antisense
AGCATAATGCGGCCGAGTGGTTCTC 573 77 2756 Antisense
GCATCGGCATCTTGTCGTTGATTTC 560 309 2784 Antisense
ACGATACGACAGTGCTGAGCGCCTA 37 95 2855 Antisense
Sequence Source Affymetrix Proprietary Database