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[176764_at] 7TM chemoreceptor, srx family

Description Y49C4A.4 /REP_DB=WormBase Gene ID /WP=CE26127 /GB=AAK72315.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_total > 54      4grp_total > 03      6grp_cgc > 56      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 124
1 2 3 4 range
A 7.5
(-2.7)
A 		4.7
(-3)
A 		6.9
(-2.8)
A 		70.3
(3)
A 		66
B 40.7
(3)
A 		8.3
(-2.7)
A 		6.7
(-3)
A 		13.1
(-1.9)
A 		34
C 4
(-3)
A 		11.1
(-2.7)
A 		18.4
(-2.3)
A 		128.2
(3)
A 		124
avr 17.4
(-2.1) 		8
(-3) 		10.7
(-2.7) 		70.5
(3) 		63

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 43
1 2 3 4 5 6 range
A 6.9
(-2.4)
A 		2.7
(-3)
A 		7.2
(-2.3)
A 		6.1
(-2.5)
A 		42.4
(3)
A 		13.5
(-1.4)
A 		40
B 4.9
(-3)
A 		6.1
(-2.4)
A 		17.3
(3)
A 		6.9
(-2)
A 		13.5
(1.2)
A 		14.1
(1.5)
A 		12
C 5.3
(-2.7)
A 		6.9
(-2.5)
A 		45.7
(3)
A 		3.5
(-3)
A 		3.5
(-3)
A 		24.6
(0)
A 		42
avr 5.7
(-2.8) 		5.2
(-3) 		23.4
(3) 		5.5
(-2.9) 		19.8
(1.8) 		17.4
(1) 		18
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 21
1 2 3 4 range
A 2.7
(-1.9)
A 		1
(-3)
A 		1.8
(-2.5)
A 		10.3
(3)
A 		9
B 13
(3)
A 		2
(-2.8)
A 		1.6
(-3)
A 		2.8
(-2.4)
A 		11
C 1.3
(-3)
A 		3.2
(-2.4)
A 		6.4
(-1.5)
A 		21.6
(3)
A 		20
avr 5.7
(-0.7) 		2.1
(-3) 		3.3
(-2.2) 		11.6
(3) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 12
1 2 3 4 5 6 range
A 1.3
(-2.8)
A 		0.9
(-3)
A 		1.6
(-2.6)
A 		1.6
(-2.6)
A 		12.8
(3)
A 		3.3
(-1.8)
A 		12
B 1.7
(-3)
A 		2
(-2.5)
A 		4.2
(0.9)
A 		1.8
(-2.8)
A 		5.5
(3)
A 		5.3
(2.7)
A 		4
C 2
(-2.3)
A 		2.1
(-2.2)
A 		11.6
(3)
A 		0.7
(-3)
A 		1.1
(-2.8)
A 		8.2
(1.1)
A 		11
avr 1.7
(-2.6) 		1.7
(-2.6) 		5.8
(2.2) 		1.4
(-3) 		6.5
(3) 		5.6
(1.9) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 176764_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15721
Sequence Type Exemplar sequence
Representative Public ID Y49C4A.4 NCBI
Target Description Y49C4A.4 /REP_DB=WormBase Gene ID /WP=CE26127 /GB=AAK72315.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070898(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070898 NCBI Caenorhabditis elegans Serpentine Receptor, class X family member (srx-5) (srx-5) mRNA, complete cds. 11/11 None
GENEFINDER00000005338 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:699909:710218:1 11/11 None
Y49C4A.4 ENSEMBL cdna:known chromosome:CEL140:V:699909:701499:1 gene:Y49C4A.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:699908-701499(+) 100.0 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, srx family
Gene Symbol srx-5
Ensembl Y49C4A.4
Entrez Gene 190063 Entrez gene
SwissProt Q965U1 EMBL-EBI
WormBase CE26127 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_503299 Serpentine Receptor, class X family member (srx-5) [Caenorhabditis elegans] gb|AAK72315.1| Serpentine receptor, class x protein 5 [Caenorhabditis elegans] 1.0E-168
blast NP_503299 Serpentine Receptor, class X family member (srx-5) [Caenorhabditis elegans] gb|AAK72315.1| Serpentine receptor, class x protein 5 [Caenorhabditis elegans] 1.0E-145
blast NP_503301 Serpentine Receptor, class BC (class B-like) family member (srbc-38) [Caenorhabditis elegans] gb|AAW88387.1| Hypothetical protein Y49C4A.2 [Caenorhabditis elegans] 1.0E-138
blast NP_503300 Serpentine Receptor, class BC (class B-like) family member (srbc-37) [Caenorhabditis elegans] gb|AAW88388.1| Hypothetical protein Y49C4A.3 [Caenorhabditis elegans] 1.0E-129
blast NP_504861 Serpentine Receptor, class X family member (srx-6) [Caenorhabditis elegans] gb|AAG24053.1| Serpentine receptor, class x protein 6 [Caenorhabditis elegans] 1.0E-125
blast CAE65415 Hypothetical protein CBG10369 [Caenorhabditis briggsae] 1.0E-90
Protein Domains
Database ID Description E-Value
Pfam IPR002892 EMBL-EBI Protein of unknown function DUF40 5.1E-72
Pfam IPR002892 EMBL-EBI Protein of unknown function DUF40 8.8E-81
Pfam IPR002892 EMBL-EBI Protein of unknown function DUF40 4.2E-62
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_503299.1 6 7-29,39-61,125-147,177-199,220-242,252-274
Y49C4A.4 6 7-29,39-61,125-147,177-199,220-242,252-274
GENEFINDER00000005338 25 7-29,39-61,125-147,177-199,220-239,273-295,315-337,352-374,394-416,448-470,493-515,520-542,562-584,594-616,637-659,692-714,735-757,767-786,836-855,939-956,976-998,1008-1030,1051-1073,1104-1123,1143-1165
Sequence
Target Sequence 
>C. ELEGANS:176764_AT
aaactatatctttacattccgccgaacacttttcctgtttttcgttattattgcgctgac
atcattttcagctgcatgcacccaatatttcttcccatgttgcgttataatagttgatat
cgatataatgtcgtacatgtttttgagtatcgacggagtttactcgtactccaacgctat
tttgctagtttacaacatattttgcacgttactatccactttttgctacgtgtctgtgtt
aatttcaatccggagagcaaacaaaaatgtggtgaataacattcatagtaacactaagaa
acaagaagctcggtacctattccaatttgtggtcatctcaattttctatgtggccacgtg
gatttcttttgaaactctgccatatattgtcccgcctgaccaacccatatggttttcgtc
tgttccatttttgctcacacttaactgttcct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAACTATATCTTTACATTCCGCCGA 52 129 360 Antisense
GACATCATTTTCAGCTGCATGCACC 581 369 417 Antisense
CATGCACCCAATATTTCTTCCCATG 580 209 434 Antisense
ACTCGTACTCCAACGCTATTTTGCT 386 99 521 Antisense
ATTTTGCACGTTACTATCCACTTTT 532 13 558 Antisense
ATCCACTTTTTGCTACGTGTCTGTG 473 39 573 Antisense
AGAAGCTCGGTACCTATTCCAATTT 26 73 663 Antisense
CTCAATTTTCTATGTGGCCACGTGG 68 227 696 Antisense
GAAACTCTGCCATATATTGTCCCGC 582 357 730 Antisense
ACCCATATGGTTTTCGTCTGTTCCA 67 91 762 Antisense
TTTTTGCTCACACTTAACTGTTCCT 276 675 787 Antisense
Sequence Source Affymetrix Proprietary Database