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[176762_at] 7TM chemoreceptor, srx family

Description Y49C4A.5 /REP_DB=WormBase Gene ID /WP=CE26128 /GB=AAK72316.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation
Cluster 6grp_total > 29      4grp_total > 20      6grp_cgc > 02      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 92
1 2 3 4 range
A 77.9
(-0.5)
A 		87.8
(0.2)
A 		43.8
(-3)
A 		125.1
(3)
A 		81
B 83.5
(3)
A 		39.4
(-3)
A 		54.6
(-0.9)
A 		50.8
(-1.4)
P 		44
C 64.3
(-1.5)
A 		98.4
(0.8)
A 		42
(-3)
A 		130.9
(3)
P 		89
avr 75.2
(0.1) 		75.2
(0.1) 		46.8
(-3) 		102.3
(3) 		56

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 82
1 2 3 4 5 6 range
A 101.1
(2.9)
A 		54.6
(-0.5)
A 		27.6
(-2.5)
A 		45.6
(-1.2)
A 		102.6
(3)
A 		21
(-3)
A 		82
B 57.4
(1.6)
A 		65.8
(3)
A 		28.6
(-3)
A 		52.7
(0.9)
A 		46.6
(-0.1)
A 		54.8
(1.2)
A 		37
C 65.6
(3)
A 		60.3
(2.3)
A 		58.7
(2.1)
A 		48.3
(0.7)
A 		62.2
(2.5)
A 		20.9
(-3)
A 		45
avr 74.7
(3) 		60.2
(1) 		38.3
(-2.1) 		48.9
(-0.6) 		70.5
(2.4) 		32.2
(-3) 		43
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 19
1 2 3 4 range
A 28.4
(3)
A 		19.1
(-0.3)
A 		11.5
(-3)
A 		18.3
(-0.6)
A 		17
B 26.6
(3)
A 		9.7
(-3)
A 		12.7
(-1.9)
A 		10.8
(-2.6)
P 		17
C 21.3
(-0.1)
A 		28.3
(3)
A 		14.6
(-3)
A 		22.1
(0.3)
P 		14
avr 25.4
(3) 		19
(-0.1) 		12.9
(-3) 		17.1
(-1) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 18.6
(0.1)
A 		19.4
(0.3)
A 		6
(-2.8)
A 		11.6
(-1.5)
A 		31
(3)
A 		5.1
(-3)
A 		26
B 20
(2.2)
A 		21.9
(3)
A 		6.9
(-3)
A 		14
(-0.2)
A 		18.9
(1.8)
A 		20.5
(2.4)
A 		15
C 24.3
(3)
A 		18.4
(1)
A 		14.9
(-0.3)
A 		9.7
(-2.1)
A 		20.1
(1.5)
A 		7
(-3)
A 		17
avr 21
(2) 		19.9
(1.5) 		9.3
(-3) 		11.8
(-1.9) 		23.3
(3) 		10.9
(-2.3) 		14
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 176762_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15382
Sequence Type Exemplar sequence
Representative Public ID Y49C4A.5 NCBI
Target Description Y49C4A.5 /REP_DB=WormBase Gene ID /WP=CE26128 /GB=AAK72316.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070895(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070895 NCBI Caenorhabditis elegans Serpentine Receptor, class X family member (srx-4) (srx-4) mRNA, complete cds. 11/11 None
SNAP00000005332 ENSEMBL cdna:SNAP chromosome:CEL140:V:690705:692172:-1 11/11 None
GENEFINDER00000005339 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:690705:699612:-1 11/11 None
Y49C4A.5 ENSEMBL cdna:known chromosome:CEL140:V:690705:692600:-1 gene:Y49C4A.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:690704-692600(-) 99.9 100.0
Public Domain and Genome References
Gene Title 7TM chemoreceptor, srx family
Gene Symbol srx-4
Ensembl Y49C4A.5
Entrez Gene 190064 Entrez gene
SwissProt Q965U4 EMBL-EBI
WormBase CE26128 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_503298 Y49C4A.8a [Caenorhabditis elegans] gb|AAK72318.1| Hypothetical protein Y49C4A.8a [Caenorhabditis elegans] 0.0
blast NP_872148 Y49C4A.8b [Caenorhabditis elegans] gb|AAO25979.1| Hypothetical protein Y49C4A.8b [Caenorhabditis elegans] 0.0
blast AAB42344 Udp-glucuronosyltransferase protein 28 [Caenorhabditis elegans] ref|NP_491437.1| C10H11.4 [Caenorhabditis elegans] 0.0
blast NP_503296 Serpentine Receptor, class X family member (srx-4) [Caenorhabditis elegans] gb|AAK72316.1| Serpentine receptor, class x protein 4 [Caenorhabditis elegans] 1.0E-163
blast NP_503296 Serpentine Receptor, class X family member (srx-4) [Caenorhabditis elegans] gb|AAK72316.1| Serpentine receptor, class x protein 4 [Caenorhabditis elegans] 1.0E-132
blast NP_505329 Serpentine Receptor, class X family member (srx-3) [Caenorhabditis elegans] gb|AAC48108.2| Serpentine receptor, class x protein 3 [Caenorhabditis elegans] 4.0E-81
blast NP_505329 Serpentine Receptor, class X family member (srx-3) [Caenorhabditis elegans] gb|AAC48108.2| Serpentine receptor, class x protein 3 [Caenorhabditis elegans] 6.0E-62
blast CAE72070 Hypothetical protein CBG19156 [Caenorhabditis briggsae] 2.0E-51
Protein Domains
Database ID Description E-Value
Pfam IPR003002 EMBL-EBI 7TM chemoreceptor, subfamily 1 8.8E-6
Pfam IPR002213 EMBL-EBI UDP-glucoronosyl/UDP-glucosyl transferase 8.7E-28
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_503296.1 7 10-32,44-66,86-108,121-143,180-202,224-246,256-278
Y49C4A.5 7 10-32,44-66,86-108,121-143,180-202,224-246,256-278
SNAP00000005332 4 16-38,75-97,119-141,151-173
GENEFINDER00000005339 15 632-654,682-704,719-741,791-810,820-842,889-911,939-961,1040-1062,1085-1107,1119-1141,1161-1183,1196-1218,1255-1277,1299-1321,1331-1353
Sequence
Target Sequence 
>C. ELEGANS:176762_AT
tatgatcataattacctctcctactcgtacaatgtgatagaaggagttgcaaactcgtcg
aacaactttgatgttcctttaaacgctctcagctctgtggtttcggcgtttttctacgtt
atgatattctggacagttcacaaatcgacgcccaactcatcaactggtgaagagcaaaaa
ttacggagggagcgagatgtcaaatacgccttccaattctgccttcttctgatattttac
atctgcgcatggtccctgttccgaattctgcccctaatcatcgcaaatcatggaatcgag
tggtttgtgttgattccaatgttttacacattgaattgcacttccaatgcaataatttat
ttgggattcaatagcgaggtccaggaaaacttaaagcctcaaaaactgcaatccattctt
cgcattctaaaatttatgaagcctgaaccatcctttcaagacgtcagtttggcaaacgcg
acgaatgcatcaagtgtcgctccgatccgccacgttgcactacgatttgttcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TATGATCATAATTACCTCTCCTACT 613 655 478 Antisense
ACCTCTCCTACTCGTACAATGTGAT 656 87 491 Antisense
TTAAACGCTCTCAGCTCTGTGGTTT 434 681 556 Antisense
CTGGACAGTTCACAAATCGACGCCC 336 241 606 Antisense
AGATGTCAAATACGCCTTCCAATTC 664 65 672 Antisense
CAATTCTGCCTTCTTCTGATATTTT 191 181 691 Antisense
ATATTTTACATCTGCGCATGGTCCC 77 19 709 Antisense
AATTCTGCCCCTAATCATCGCAAAT 494 177 741 Antisense
AAACTGCAATCCATTCTTCGCATTC 50 127 880 Antisense
GAACCATCCTTTCAAGACGTCAGTT 182 345 922 Antisense
GCCACGTTGCACTACGATTTGTTCC 311 279 986 Antisense
Sequence Source Affymetrix Proprietary Database