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[176451_at]

Description Y37E11AR.D /REP_DB=WormBase Gene ID /WP=CE21549 /CHR=4 /FEA=Sanger Annotation /DEF=(ST.LOUIS)
Cluster 6grp_highest_10_10 > 62      6grp_high1_10_10 > 29      4grp_highest_8_8 > 31      4grp_high_8_8 > 05      6grp_highest_nonorm > 80      6grp_total > 27      4grp_total > 03      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Decrease      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 529
1 2 3 4 range
A 245.7
(-2)
P 		177.6
(-3)
P 		187.1
(-2.9)
P 		602.7
(3)
P 		425
B 246.2
(-1.5)
P 		233.2
(-1.7)
P 		155.4
(-3)
P 		519.6
(3)
P 		364
C 233
(-2)
P 		188.4
(-2.5)
P 		140.4
(-3)
P 		669.8
(3)
P 		529
avr 241.6
(-1.9) 		199.7
(-2.5) 		161
(-3) 		597.4
(3) 		436

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 167
1 2 3 4 5 6 range
A 299.9
(3)
P 		156.4
(-2.2)
P 		183.8
(-1.2)
P 		133.5
(-3)
P 		198.7
(-0.6)
P 		189.4
(-1)
P 		166
B 296.9
(3)
P 		258.4
(1.4)
P 		208.4
(-0.6)
P 		149
(-3)
P 		177.2
(-1.9)
P 		244.1
(0.9)
P 		148
C 140.6
(-2.6)
P 		258.7
(3)
P 		187.3
(-0.4)
P 		133.1
(-3)
P 		182
(-0.7)
P 		206.2
(0.5)
P 		126
avr 245.8
(3) 		224.5
(1.8) 		193.2
(0.1) 		138.5
(-3) 		186
(-0.3) 		213.2
(1.2) 		107
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 77
1 2 3 4 range
A 89.4
(3)
P 		38.5
(-3)
P 		48.9
(-1.8)
P 		88.2
(2.9)
P 		51
B 78.5
(0.4)
P 		57.6
(-1.3)
P 		36
(-3)
P 		110.7
(3)
P 		75
C 77.1
(-0.4)
P 		54.2
(-2.5)
P 		48.9
(-3)
P 		112.9
(3)
P 		64
avr 81.7
(0.8) 		50.1
(-2.4) 		44.6
(-3) 		103.9
(3) 		59

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 55.3
(1.9)
P 		55.6
(2)
P 		40
(-1.6)
P 		33.9
(-3)
P 		60
(3)
P 		46.1
(-0.2)
P 		26
B 103.3
(3)
P 		86
(1.4)
P 		50.6
(-2)
P 		39.5
(-3)
P 		72
(0.1)
P 		91
(1.8)
P 		64
C 52.1
(-0.1)
P 		78.9
(3)
P 		47.7
(-0.6)
P 		26.8
(-3)
P 		58.9
(0.7)
P 		69
(1.9)
P 		52
avr 70.2
(2.5) 		73.5
(3) 		46.1
(-1.1) 		33.4
(-3) 		63.6
(1.5) 		68.7
(2.3) 		40
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 176451_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19200
Sequence Type Exemplar sequence
Representative Public ID Y37E11AR.D NCBI
Target Description Y37E11AR.D /REP_DB=WormBase Gene ID /WP=CE21549 /CHR=4 /FEA=Sanger Annotation /DEF=(ST.LOUIS)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_068008(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_068008 NCBI Caenorhabditis elegans Y37E11AR.2 (Y37E11AR.2) mRNA, complete cds. 11/11 None
SNAP00000021667 ENSEMBL cdna:SNAP chromosome:CEL140:IV:3742823:3747208:1 11/11 None
GENEFINDER00000021677 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:3742579:3747208:1 11/11 None
Y37E11AR.2 ENSEMBL cdna:known chromosome:CEL140:IV:3744051:3747650:1 gene:Y37E11AR.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:3736473-3747214(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl Y37E11AR.2
Entrez Gene 177138 Entrez gene
SwissProt Q965X6 EMBL-EBI
WormBase CE21549 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:15010_AT seven in absentia (SINA) family protein at
ATH1-121501:253838_AT seven in absentia (SINA) family protein at
CANINE:1592557_AT similar to seven in absentia homolog 1 isoform b cfa
CANINE_2:CFA.20099.1.S1_S_AT similar to seven in absentia homolog 1 isoform b cfa
CANINE_2:CFAAFFX.15719.1.S1_AT similar to seven in absentia homolog 1 isoform b cfa
DROSOPHILA_2:1632100_S_AT seven in absentia dm
DROSGENOME1:153438_AT seven in absentia dm
CHICKEN:GGA.2757.1.S1_AT seven in absentia homolog 1 (Drosophila) gga
HU35KSUBD:RC_AA446342_AT seven in absentia homolog 1 (Drosophila) hs
HUGENEFL:U63295_AT seven in absentia homolog 1 (Drosophila) hs
HG-U133A:202981_X_AT seven in absentia homolog 1 (Drosophila) hs
HG-U133_PLUS_2:202981_X_AT seven in absentia homolog 1 (Drosophila) hs
HG-U133A_2:202981_X_AT seven in absentia homolog 1 (Drosophila) hs
U133_X3P:G4506946_3P_X_AT seven in absentia homolog 1 (Drosophila) hs
U133_X3P:G4506946_3P_AT seven in absentia homolog 1 (Drosophila) hs
U133_X3P:HS.295923.0.S1_3P_A_AT seven in absentia homolog 1 (Drosophila) hs
U133_X3P:HS.188990.0.S1_3P_X_AT seven in absentia homolog 1 (Drosophila) hs
U133_X3P:232365_3P_AT seven in absentia homolog 1 (Drosophila) hs
HG-U133A_2:202980_S_AT seven in absentia homolog 1 (Drosophila) hs
HG-FOCUS:202980_S_AT seven in absentia homolog 1 (Drosophila) hs
HG-U133_PLUS_2:202980_S_AT seven in absentia homolog 1 (Drosophila) hs
HG-U133A:202980_S_AT seven in absentia homolog 1 (Drosophila) hs
HG-U133_PLUS_2:232365_AT seven in absentia homolog 1 (Drosophila) hs
HG-U133B:232365_AT seven in absentia homolog 1 (Drosophila) hs
HG-U95AV2:32160_AT seven in absentia homolog 1 (Drosophila) hs
HG-U95D:87291_AT seven in absentia homolog 1 (Drosophila) hs
HU35KSUBA:RC_AA281770_AT Seven in absentia homolog 1 (Drosophila) hs
U133_X3P:HS.295923.1.A2_3P_AT Seven in absentia homolog 1 (Drosophila) hs
U133_X3P:HS.295923.1.A1_3P_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U133A_2:221833_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U133_PLUS_2:221833_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U133A:221833_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U133A_2:221834_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U133_PLUS_2:221834_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U133A:221834_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U95AV2:32161_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U95D:75134_AT Seven in absentia homolog 1 (Drosophila) hs
HG-U95E:91050_AT Seven in absentia homolog 1 (Drosophila) hs
MOE430A:1423390_AT seven in absentia 1A mm
MOUSE430A_2:1423390_AT seven in absentia 1A mm
MOUSE430_2:1423390_AT seven in absentia 1A mm
MOUSE430_2:1449733_S_AT seven in absentia 1A mm
MOUSE430A_2:1449733_S_AT seven in absentia 1A mm
MOE430A:1449733_S_AT seven in absentia 1A mm
MOUSE430_2:1419404_S_AT seven in absentia 1A mm
MOE430A:1419404_S_AT seven in absentia 1A mm
MOUSE430A_2:1419404_S_AT seven in absentia 1A mm
MU11KSUBB:Z19579_S_AT seven in absentia 1A mm
MU11KSUBB:Z19580_S_AT seven in absentia 1A mm
MG-U74AV2:100985_AT seven in absentia 1A mm
MG-U74BV2:113553_AT Seven in absentia 1A (Siah1a), mRNA mm
MU19KSUBA:TC16686_AT Seven in absentia 1A (Siah1a), mRNA mm
MU19KSUBA:TC16686_G_AT Seven in absentia 1A (Siah1a), mRNA mm
MU19KSUBA:TC18825_AT Seven in absentia 1A (Siah1a), mRNA mm
MU19KSUBB:TC28122_AT Seven in absentia 1A (Siah1a), mRNA mm
MU19KSUBB:TC28122_G_AT Seven in absentia 1A (Siah1a), mRNA mm
RG-U34B:RC_AA923973_AT seven in absentia 1A rn
RAE230A:1387266_AT seven in absentia 1A rn
RAT230_2:1387266_AT seven in absentia 1A rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6511 ubiquitin-dependent protein catabolism inferred from electronic annotation QuickGO AmiGO
7275 development inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK68432 Hypothetical protein Y37E11AR.2 [Caenorhabditis elegans] ref|NP_500409.1| Y37E11AR.2 [Caenorhabditis elegans] 0.0
blast CAE63753 Hypothetical protein CBG08288 [Caenorhabditis briggsae] 1.0E-179
blast CAE63753 Hypothetical protein CBG08288 [Caenorhabditis briggsae] 1.0E-177
blast Q965X6 Ubiquitin ligase sia-1 (Seven in absentia homolog 1) gb|AAB94380.1| seven-in-absentia protein homologue-1 [Caenorhabditis elegans] 1.0E-174
blast CAE63753 Hypothetical protein CBG08288 [Caenorhabditis briggsae] 1.0E-174
Protein Domains
Database ID Description E-Value
Pfam IPR004162 EMBL-EBI Seven in absentia protein family 1.0E-126
Pfam IPR004162 EMBL-EBI Seven in absentia protein family 1.0E-126
Pfam IPR004162 EMBL-EBI Seven in absentia protein family 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:176451_AT
tccatgcaaattctctacgtccggctgccccctgaacttccatcacgctgataagaccga
gcacgaggagctctgcgaattccgaccctactgctgcccgtgccctggagctagctgcaa
gtggcagggaggcttgtcggatgtgatggagcatttgaagaagatccacaagagcatcac
gacgcttcaaggcgaggatatcgtcttcctggccactgacatcaatcttcctggagcagt
tgactgggttatgatgcagagctgctttgactataattttatgttggtgctcgagaagca
ggaaaagtacgatccagctcagccaactcagatgttctacgcagtcgttcagctgattgg
ctcgaagaaggaagctgataactttgtgtaccggcttgagctatcggcgagccgccggag
aatgtcatgggaagccacaccgagaagcatccacgagggggtggtagtggccattcaaca
gtcggattgcctagcgttcgattcaaatgctgcacagc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCATGCAAATTCTCTACGTCCGGC 451 587 1288 Antisense
GAGCATCACGACGCTTCAAGGCGAG 317 389 1459 Antisense
AAGGCGAGGATATCGTCTTCCTGGC 436 161 1476 Antisense
CACTGACATCAATCTTCCTGGAGCA 266 199 1501 Antisense
AGCTCAGCCAACTCAGATGTTCTAC 630 79 1603 Antisense
TGTTCTACGCAGTCGTTCAGCTGAT 524 561 1620 Antisense
GTGTACCGGCTTGAGCTATCGGCGA 547 467 1673 Antisense
CCACACCGAGAAGCATCCACGAGGG 497 275 1722 Antisense
GGTAGTGGCCATTCAACAGTCGGAT 404 503 1750 Antisense
ACAGTCGGATTGCCTAGCGTTCGAT 557 105 1765 Antisense
GCGTTCGATTCAAATGCTGCACAGC 702 289 1781 Antisense
Sequence Source Affymetrix Proprietary Database