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[176356_s_at]

Description Y71G12B.E /REP_DB=WormBase Gene ID /WP=CE26252 /CHR=1 /FEA=Sanger Annotation /DEF=(ST.LOUIS)
Cluster 6grp_highest_10_10 > 22      6grp_high1_10_10 > 03      4grp_high_8_8 > 53      6grp_highest_nonorm > 60      6grp_total > 34      4grp_total > 58      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 998
1 2 3 4 range
A 416.9
(-0.9)
P 		860.1
(2.9)
P 		873.1
(3)
P 		175
(-3)
A 		698
B 566.1
(0.5)
P 		857
(3)
P 		847.6
(2.9)
P 		151.9
(-3)
P 		705
C 633.7
(-0.1)
P 		1149.3
(3)
P 		1037.8
(2.3)
P 		151
(-3)
A 		998
avr 538.9
(-0.1) 		955.5
(3) 		919.5
(2.7) 		159.3
(-3) 		796

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 390
1 2 3 4 5 6 range
A 657.3
(3)
P 		480
(0.3)
P 		542
(1.2)
P 		333.3
(-2)
P 		267.4
(-3)
P 		351.8
(-1.7)
P 		390
B 491.5
(3)
P 		471.2
(2.4)
P 		458.2
(2)
P 		336.3
(-1.8)
P 		299.1
(-3)
P 		340.7
(-1.7)
P 		192
C 596
(3)
P 		467.1
(0.6)
P 		474.5
(0.8)
P 		268.5
(-3)
P 		379.4
(-1)
P 		387.5
(-0.8)
P 		328
avr 581.6
(3) 		472.8
(0.6) 		491.6
(1) 		312.7
(-3) 		315.3
(-2.9) 		360
(-1.9) 		269
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 336
1 2 3 4 range
A 151.8
(0.7)
P 		186.7
(1.8)
P 		228.2
(3)
P 		25.6
(-3)
A 		203
B 180.5
(2)
P 		211.7
(3)
P 		196.4
(2.5)
P 		32.4
(-3)
P 		179
C 209.8
(0.3)
P 		330.4
(2.4)
P 		361.7
(3)
P 		25.5
(-3)
A 		336
avr 180.7
(0.9) 		242.9
(2.5) 		262.1
(3) 		27.8
(-3) 		234

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 167
1 2 3 4 5 6 range
A 121.2
(-0.3)
P 		170.7
(3)
P 		118
(-0.5)
P 		84.5
(-2.7)
P 		80.7
(-3)
P 		85.7
(-2.7)
P 		90
B 171
(3)
P 		156.9
(2)
P 		111.3
(-1.4)
P 		89.1
(-3)
P 		121.5
(-0.6)
P 		127
(-0.2)
P 		82
C 220.9
(3)
P 		142.5
(0.2)
P 		120.8
(-0.6)
P 		54
(-3)
P 		122.8
(-0.5)
P 		129.7
(-0.3)
P 		167
avr 171
(3) 		156.7
(2.1) 		116.7
(-0.4) 		75.9
(-3) 		108.3
(-1) 		114.1
(-0.6) 		95
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 176356_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18756
Sequence Type Exemplar sequence
Representative Public ID Y71G12B.E NCBI
Target Description Y71G12B.E /REP_DB=WormBase Gene ID /WP=CE26252 /CHR=1 /FEA=Sanger Annotation /DEF=(ST.LOUIS)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_058487(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_058487 NCBI Caenorhabditis elegans Y71G12B.24 (Y71G12B.24) mRNA, complete cds. 11/11 None
SNAP00000001790 ENSEMBL cdna:SNAP chromosome:CEL140:I:1740764:1777506:-1 11/11 None
GENEFINDER00000001834 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:1740764:1751056:-1 11/11 None
Y71G12B.24 ENSEMBL cdna:known chromosome:CEL140:I:1740648:1751056:-1 gene:Y71G12B.24 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:1740763-1743669(-) 85.53 100.0
Public Domain and Genome References
Gene Title
Ensembl Y71G12B.24
Entrez Gene 171737 Entrez gene
SwissProt Q95XN2 EMBL-EBI
WormBase CE27028 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1588123_AT similar to mitochondrial matrix processing protease, alpha subunit cfa
CANINE_2:CFA.10580.1.S1_A_AT similar to mitochondrial matrix processing protease, alpha subunit cfa
CANINE_2:CFA.10580.2.S1_A_AT similar to mitochondrial matrix processing protease, alpha subunit cfa
CANINE_2:CFA.10580.2.S1_S_AT similar to mitochondrial matrix processing protease, alpha subunit cfa
CANINE_2:CFA.19771.1.S1_S_AT similar to mitochondrial matrix processing protease, alpha subunit cfa
CANINE_2:CFAAFFX.30091.1.S1_AT similar to mitochondrial matrix processing protease, alpha subunit cfa
DROSOPHILA_2:1628751_AT dm
DROSGENOME1:152232_AT dm
CHICKEN:GGA.4744.3.S1_A_AT peptidase (mitochondrial processing) alpha gga
CHICKEN:GGAAFFX.12688.1.S1_S_AT peptidase (mitochondrial processing) alpha gga
HG-U133A:212088_AT peptidase (mitochondrial processing) alpha hs
HG-U133A_2:212088_AT peptidase (mitochondrial processing) alpha hs
HG-U133_PLUS_2:212088_AT peptidase (mitochondrial processing) alpha hs
HU35KSUBC:RC_N51632_AT peptidase (mitochondrial processing) alpha hs
HU35KSUBD:RC_H26970_S_AT peptidase (mitochondrial processing) alpha hs
HUGENEFL:D50913_AT peptidase (mitochondrial processing) alpha hs
U133_X3P:HS.75353.0.A1_3P_AT peptidase (mitochondrial processing) alpha hs
HG-U95AV2:36602_AT peptidase (mitochondrial processing) alpha hs
MG-U74AV2:96848_AT peptidase (mitochondrial processing) alpha mm
MG-U74BV2:111131_G_AT peptidase (mitochondrial processing) alpha mm
MG-U74CV2:134130_AT peptidase (mitochondrial processing) alpha mm
MG-U74CV2:168492_AT peptidase (mitochondrial processing) alpha mm
MOE430A:1424661_AT peptidase (mitochondrial processing) alpha mm
MOUSE430A_2:1424661_AT peptidase (mitochondrial processing) alpha mm
MOUSE430_2:1424661_AT peptidase (mitochondrial processing) alpha mm
MOE430A:1424662_AT peptidase (mitochondrial processing) alpha mm
MOUSE430A_2:1424662_AT peptidase (mitochondrial processing) alpha mm
MOUSE430_2:1424662_AT peptidase (mitochondrial processing) alpha mm
MU19KSUBA:TC24641_AT Peptidase (mitochondrial processing) alpha, mRNA (cDNA clone MGC:18910 IMAGE:4241697) mm
MU19KSUBA:TC24641_G_AT Peptidase (mitochondrial processing) alpha, mRNA (cDNA clone MGC:18910 IMAGE:4241697) mm
MU19KSUBC:TC41048_AT Peptidase (mitochondrial processing) alpha, mRNA (cDNA clone MGC:18910 IMAGE:4241697) mm
RAE230A:1371008_AT peptidase (mitochondrial processing) alpha rn
RAT230_2:1371008_AT peptidase (mitochondrial processing) alpha rn
RG-U34A:M57728_G_AT peptidase (mitochondrial processing) alpha rn
RG-U34A:M57728_AT peptidase (mitochondrial processing) alpha rn
RG-U34C:RC_AI176063_AT peptidase (mitochondrial processing) alpha rn
RAE230A:1375947_AT Peptidase (mitochondrial processing) alpha rn
RAT230_2:1375947_AT Peptidase (mitochondrial processing) alpha rn
RG-U34B:RC_AI029484_AT Peptidase (mitochondrial processing) alpha rn
RG-U34C:RC_AI171856_AT Peptidase (mitochondrial processing) alpha rn
YEAST_2:1770209_AT Larger subunit of the mitochondrial processing protease, essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4222 metalloendopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK73925 Hypothetical protein Y71G12B.24 [Caenorhabditis elegans] ref|NP_490888.1| Y71G12B.24 [Caenorhabditis elegans] 0.0
blast CAE74438 Hypothetical protein CBG22171 [Caenorhabditis briggsae] 0.0
blast AAK73926 Hypothetical protein Y71G12B.25 [Caenorhabditis elegans] ref|NP_490892.2| Y71G12B.25 [Caenorhabditis elegans] 0.0
blast AAF59168 CG8728-PA [Drosophila melanogaster] ref|NP_610333.1| CG8728-PA [Drosophila melanogaster] gb|AAL13552.1| GH09295p [Drosophila melanogaster] 1.0E-99
Protein Domains
Database ID Description E-Value
Pfam IPR007863 EMBL-EBI Peptidase M16, C-terminal 4.3E-38
Pfam IPR001431 EMBL-EBI Peptidase M16, insulinase-like 1.6E-20
Pfam IPR007863 EMBL-EBI Peptidase M16, C-terminal 4.3E-38
Pfam IPR001431 EMBL-EBI Peptidase M16, insulinase-like 1.6E-20
Pfam IPR007863 EMBL-EBI Peptidase M16, C-terminal 7.4E-32
Pfam IPR001431 EMBL-EBI Peptidase M16, insulinase-like 1.6E-20
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000001790 9 39-58,73-95,108-130,167-189,196-218,246-268,280-302,312-331,396-418
Sequence
Target Sequence 
>C. ELEGANS:176356_S_AT
tacgcccgaatgtacacagaactaatgaatcgacatcactggatctacagtgcaattgca
cataatcactcatatagtgatagtggtgtgttcacagttacagcaagctccccaccggaa
aatatcaacgatgctctgattcttcttgttcatcaaatccttcaacttcaacagggcgtc
gagccgactgagctcgcgagagccagaactcaactcagaagccatttaatgatgaatttg
gaagtacgaccagtgttatttgaggatatggtccgacaagtgttgggacacggcgacaga
aaacagccagaggagtatgcggagaaaattgaaaaagtgaccaattcggacatcattcgt
gtcacagaacgtctgctagcctccaagccatcactggtcggatacggtgatattaaaaag
ctcaaagatctacgatcactggatcaggcggtcgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TACGCCCGAATGTACACAGAACTAA 405 649 232 Antisense
TGAATCGACATCACTGGATCTACAG 532 575 257 Antisense
GCAATTGCACATAATCACTCATATA 13 323 283 Antisense
GTGTTCACAGTTACAGCAAGCTCCC 556 485 319 Antisense
AGCTCCCCACCGGAAAATATCAACG 262 79 337 Antisense
CTTCTTGTTCATCAAATCCTTCAAC 413 221 373 Antisense
TCAACTTCAACAGGGCGTCGAGCCG 653 629 393 Antisense
CGTCGAGCCGACTGAGCTCGCGAGA 657 245 408 Antisense
AGCTCGCGAGAGCCAGAACTCAACT 282 81 422 Antisense
GAGCCAGAACTCAACTCAGAAGCCA 281 385 431 Antisense
ACGATCACTGGATCAGGCGGTCGCT 628 93 663 Antisense
Sequence Source Affymetrix Proprietary Database