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[176162_at]

Description Y105E8B.PP /REP_DB=WormBase Gene ID /WP=CE24099 /CHR=1 /FEA=Sanger Annotation /DEF=(HINXTON)
Cluster 6grp_highest_10_10 > 26      6grp_high1_10_10 > 52      4grp_highest_8_8 > 11      4grp_high_8_8 > 47      6grp_highest_nonorm > 54      6grp_total > 62      4grp_total > 41      6grp_highest_sub > 03      6grp_high1_sub > 03      6grp_total_sub > Hat      6grp_rule_based > S3      4grp_rule_based > L3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 975
1 2 3 4 range
A 924.6
(-3)
P 		1602.4
(1.4)
P 		1856.6
(3)
P 		1339.6
(-0.3)
P 		932
B 881.2
(-3)
P 		1546
(1.1)
P 		1845.7
(3)
P 		1169.1
(-1.2)
P 		965
C 1006.1
(-3)
P 		1819.6
(3)
P 		1701.8
(2.1)
P 		1231.9
(-1.3)
P 		814
avr 937.3
(-3) 		1656
(2) 		1801.4
(3) 		1246.9
(-0.9) 		864

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 986
1 2 3 4 5 6 range
A 875.5
(-3)
P 		1568.6
(1.2)
P 		1861.4
(3)
P 		1611
(1.5)
P 		1081.5
(-1.7)
P 		1178.9
(-1.2)
P 		986
B 929.1
(-3)
P 		1348.1
(0.8)
P 		1589.6
(3)
P 		1216.9
(-0.4)
P 		1157.6
(-0.9)
P 		1115.7
(-1.3)
P 		661
C 1108.5
(-2)
P 		1300.5
(-0.7)
P 		1824.1
(3)
P 		1377
(-0.1)
P 		1308
(-0.6)
P 		968.8
(-3)
P 		855
avr 971
(-3) 		1405.7
(0.3) 		1758.4
(3) 		1401.6
(0.3) 		1182.4
(-1.4) 		1087.8
(-2.1) 		787
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 397
1 2 3 4 range
A 336.7
(-0.1)
P 		347.8
(0.1)
P 		485.3
(3)
P 		196.1
(-3)
P 		289
B 281
(-1.9)
P 		381.8
(1.5)
P 		427.7
(3)
P 		249.1
(-3)
P 		179
C 333
(-1)
P 		523.2
(1.9)
P 		593.1
(3)
P 		207.7
(-3)
P 		385
avr 316.9
(-0.9) 		417.6
(1.2) 		502
(3) 		217.6
(-3) 		284

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 397
1 2 3 4 5 6 range
A 161.4
(-3)
P 		557.9
(3)
P 		405.4
(0.7)
P 		408.6
(0.7)
P 		326.3
(-0.5)
P 		287
(-1.1)
P 		397
B 323.3
(-3)
P 		448.7
(2.1)
P 		386
(-0.4)
P 		322.3
(-3)
P 		470.3
(3)
P 		416
(0.8)
P 		148
C 410.9
(1.3)
P 		396.8
(0.8)
P 		464.3
(3)
P 		276.9
(-3)
P 		423.3
(1.7)
P 		324.3
(-1.5)
P 		187
avr 298.5
(-3) 		467.8
(3) 		418.6
(1.3) 		335.9
(-1.7) 		406.6
(0.8) 		342.4
(-1.4) 		169
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 176162_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18770
Sequence Type Exemplar sequence
Representative Public ID Y105E8B.PP NCBI
Target Description Y105E8B.PP /REP_DB=WormBase Gene ID /WP=CE24099 /CHR=1 /FEA=Sanger Annotation /DEF=(HINXTON)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061144(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061144 NCBI Caenorhabditis elegans Y105E8B.5 (Y105E8B.5) mRNA, complete cds. 11/11 None
SNAP00000011736 ENSEMBL cdna:SNAP chromosome:CEL140:I:14665514:14670953:1 11/11 None
GENEFINDER00000011741 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:14665514:14669366:1 11/11 None
Y105E8B.5 ENSEMBL cdna:known chromosome:CEL140:I:14665475:14669498:1 gene:Y105E8B.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:14665444-14669297(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Ensembl Y105E8B.5
Entrez Gene 173323 Entrez gene
SwissProt Q9NF11 EMBL-EBI
WormBase CE24099 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFA.4551.1.S1_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) cfa
CANINE_2:CFAAFFX.28810.1.S1_S_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) cfa
CHICKEN:GGA.3545.1.S2_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) gga
CHICKEN:GGAAFFX.3804.1.S1_S_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) gga
HG-U133_PLUS_2:202854_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
HG-U133A:202854_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
HG-FOCUS:202854_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
HG-U133A_2:202854_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
HUGENEFL:M31642_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
U133_X3P:G4504482_3P_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
HG-U95AV2:37640_AT hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
U133_X3P:HS2.384928.1.S1_3P_AT Hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
HG-U133_PLUS_2:1565446_AT Hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
HG-U95C:53029_AT Hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
HG-U95D:88602_AT Hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) hs
MU11KSUBA:J00423_S_AT hypoxanthine guanine phosphoribosyl transferase 1 mm
MG-U74AV2:160107_AT hypoxanthine guanine phosphoribosyl transferase 1 mm
MOE430A:1448736_A_AT hypoxanthine guanine phosphoribosyl transferase 1 mm
MOUSE430A_2:1448736_A_AT hypoxanthine guanine phosphoribosyl transferase 1 mm
MOUSE430_2:1448736_A_AT hypoxanthine guanine phosphoribosyl transferase 1 mm
MU19KSUBA:TC20369_S_AT Hypoxanthine guanine phosphoribosyl transferase 1, mRNA (cDNA clone MGC:6197 IMAGE:3500885) mm
RT-U34:M63983_S_AT hypoxanthine guanine phosphoribosyl transferase rn
RG-U34A:M63983_S_AT hypoxanthine guanine phosphoribosyl transferase rn
RG-U34A:AF009656MRNA_S_AT hypoxanthine guanine phosphoribosyl transferase rn
RAE230A:1370280_AT hypoxanthine guanine phosphoribosyl transferase rn
RAT230_2:1370280_AT hypoxanthine guanine phosphoribosyl transferase rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6166 purine ribonucleoside salvage inferred from electronic annotation QuickGO AmiGO
9116 nucleoside metabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5737 cytoplasm inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4422 hypoxanthine phosphoribosyltransferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB60853 Hypothetical protein Y105E8B.5 [Caenorhabditis elegans] ref|NP_493545.1| Y105E8B.5 [Caenorhabditis elegans] 1.0E-118
blast CAE72609 Hypothetical protein CBG19800 [Caenorhabditis briggsae] 1.0E-112
blast CAB60853 Hypothetical protein Y105E8B.5 [Caenorhabditis elegans] ref|NP_493545.1| Y105E8B.5 [Caenorhabditis elegans] 1.0E-111
blast CAE72609 Hypothetical protein CBG19800 [Caenorhabditis briggsae] 1.0E-105
blast AAA93522 hypoxanthine phosphoribosyltranserase 2.0E-49
Protein Domains
Database ID Description E-Value
Pfam IPR000836 EMBL-EBI Phosphoribosyltransferase 7.2E-21
Sequence
Target Sequence 
>C. ELEGANS:176162_AT
gcattcgacattccaatctgctatgacggtgatttatccggtgtcgtgattccggaaggt
cttgttagagatcgtgttcgtcgtctggctaaagacatccacgctgaaatcggaaacaaa
ccaatcgcgctgctctgcgtactcaaaggatcctataaattcttcactgccctcgtcgaa
gagctcacaaatgctcgctcatcgtgtcctgaaccaatgactgtcgattttattcgagta
aagagttacgaggatcaaatgagtactggacaaattcaaataatgggactatcgaatttg
gatgagctcaaggggaaaagtgtgctcgttgtggatgatatttcggataccggaagaact
cttgcaaaacttctctcaactttacatgagacgggcgttgagaagacctggacc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCATTCGACATTCCAATCTGCTATG 681 307 64 Antisense
GTGATTTATCCGGTGTCGTGATTCC 79 485 92 Antisense
ATCGTGTTCGTCGTCTGGCTAAAGA 450 35 134 Antisense
GGCTAAAGACATCCACGCTGAAATC 57 539 150 Antisense
ATCGGAAACAAACCAATCGCGCTGC 122 33 172 Antisense
TGCTCTGCGTACTCAAAGGATCCTA 180 579 194 Antisense
GGATCCTATAAATTCTTCACTGCCC 416 513 211 Antisense
GAGCTCACAAATGCTCGCTCATCGT 460 387 244 Antisense
GCTCATCGTGTCCTGAACCAATGAC 510 301 260 Antisense
GCAAAACTTCTCTCAACTTTACATG 184 319 427 Antisense
GACGGGCGTTGAGAAGACCTGGACC 506 377 453 Antisense
Sequence Source Affymetrix Proprietary Database