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[176013_s_at] --- /// --- /// ---

Description Y47C4A.A /REP_DB=WormBase Gene ID /WP=CE24325 /CHR=X /FEA=Sanger Annotation /DEF=(ST.LOUIS)
Cluster 6grp_high1_10_10 > 35      4grp_high_8_8 > 49      6grp_total > 25      4grp_total > 54      6grp_high1_sub > 02      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 107
1 2 3 4 range
A 158.3
(3)
P 		111
(-1.4)
P 		99.3
(-2.5)
P 		93.8
(-3)
A 		65
B 124.2
(2.2)
P 		110.4
(0.8)
P 		132.2
(3)
P 		72.8
(-3)
P 		59
C 180.2
(3)
P 		124.9
(-0.1)
P 		100
(-1.5)
P 		74
(-3)
P 		106
avr 154.2
(3) 		115.4
(-0.1) 		110.5
(-0.5) 		80.2
(-3) 		74

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 90
1 2 3 4 5 6 range
A 56.3
(-2.9)
P 		114.2
(3)
P 		55.4
(-3)
P 		62.3
(-2.3)
M 		68.3
(-1.7)
P 		93.4
(0.9)
P 		59
B 77
(0.6)
P 		96.1
(3)
P 		85.6
(1.7)
P 		73.3
(0.2)
P 		61.1
(-1.3)
P 		47.4
(-3)
P 		49
C 137.8
(3)
P 		117
(1.4)
M 		99.1
(0)
P 		69.8
(-2.3)
P 		60.1
(-3)
P 		62.4
(-2.8)
P 		78
avr 90.4
(0.6) 		109.1
(3) 		80
(-0.8) 		68.5
(-2.3) 		63.2
(-3) 		67.7
(-2.4) 		46
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 47
1 2 3 4 range
A 57.6
(3)
P 		24.1
(-1.6)
P 		26
(-1.3)
P 		13.7
(-3)
A 		44
B 39.6
(3)
P 		27.3
(-0.1)
P 		30.6
(0.8)
P 		15.5
(-3)
P 		24
C 59.7
(3)
P 		35.9
(-0)
P 		34.9
(-0.2)
P 		12.5
(-3)
P 		47
avr 52.3
(3) 		29.1
(-0.6) 		30.5
(-0.4) 		13.9
(-3) 		38

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 41
1 2 3 4 5 6 range
A 10.4
(-3)
P 		40.6
(3)
P 		12.1
(-2.7)
P 		15.8
(-1.9)
M 		20.6
(-1)
P 		22.7
(-0.6)
P 		30
B 26.8
(0.8)
P 		32
(3)
P 		20.8
(-1.7)
P 		19.4
(-2.3)
P 		24.8
(-0)
P 		17.7
(-3)
P 		14
C 51.1
(3)
P 		35.7
(0.5)
M 		25.2
(-1.2)
P 		14
(-3)
P 		19.4
(-2.1)
P 		20.9
(-1.9)
P 		37
avr 29.4
(1) 		36.1
(3) 		19.4
(-2.1) 		16.4
(-3) 		21.6
(-1.4) 		20.4
(-1.8) 		20
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 176013_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19583
Sequence Type Exemplar sequence
Representative Public ID Y47C4A.A NCBI
Target Description Y47C4A.A /REP_DB=WormBase Gene ID /WP=CE24325 /CHR=X /FEA=Sanger Annotation /DEF=(ST.LOUIS)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_182465(11), NM_075682(11), NM_067790(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_182465 NCBI Caenorhabditis elegans Y108F1.1 (Y108F1.1) mRNA, complete cds. 11/11 A 
NM_075682 NCBI Caenorhabditis elegans Y47C4A.1 (Y47C4A.1) mRNA, complete cds. 11/11 A 
NM_067790 NCBI Caenorhabditis elegans Y38F2AR.7 (Y38F2AR.7) mRNA, complete cds. 11/11 A 
GENEFINDER00000033673 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:2333967:2342876:-1 11/11 None
GENEFINDER00000027352 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:282374:286524:-1 11/11 None
SNAP00000027351 ENSEMBL cdna:SNAP chromosome:CEL140:X:283182:289659:-1 11/11 None
SNAP00000014003 ENSEMBL cdna:SNAP chromosome:CEL140:X:269016:279735:1 11/11 None
GENEFINDER00000014017 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:274498:276489:1 11/11 None
Y38F2AR.7 ENSEMBL cdna:known chromosome:CEL140:IV:2333860:2342696:-1 gene:Y38F2AR.7 11/11 A 
Y108F1.1 ENSEMBL cdna:known chromosome:CEL140:X:274498:277897:1 gene:Y108F1.1 11/11 A 
Y47C4A.1 ENSEMBL cdna:known chromosome:CEL140:X:283125:286524:-1 gene:Y47C4A.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:274497-276489(+) 76.97 99.78
chrX:284532-286524(-) 77.19 100.0
Public Domain and Genome References
Gene Title


Ensembl Y38F2AR.7
Y108F1.1
Y47C4A.1
Entrez Gene 177021 Entrez gene
189973 Entrez gene
353491 Entrez gene
SwissProt Q965V5 EMBL-EBI
Q95XS8 EMBL-EBI
WormBase CE27477 Wormbase
CE37282 Wormbase
CE27477 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1583921_AT similar to Paraplegin (Spastic paraplegia protein 7) cfa
CANINE:1583920_AT similar to Paraplegin (Spastic paraplegia protein 7) cfa
CANINE_2:CFA.11713.1.A1_AT similar to Paraplegin (Spastic paraplegia protein 7) cfa
CANINE_2:CFA.11713.1.A2_AT similar to Paraplegin (Spastic paraplegia protein 7) cfa
CANINE_2:CFAAFFX.30362.1.S1_S_AT similar to Paraplegin (Spastic paraplegia protein 7) cfa
DROSOPHILA_2:1626460_AT dm
DROSGENOME1:144043_AT dm
CHICKEN:GGA.4857.1.S1_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) gga
CHICKEN:GGA.4857.2.S1_A_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) gga
HG-U133A:202104_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133_PLUS_2:202104_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-FOCUS:202104_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133A_2:202104_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HUGENEFL:X65784_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
U133_X3P:HS.296847.2.A1_3P_A_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
U133_X3P:HS.272480.0.S1_3P_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
U133_X3P:HS.183957.0.A1_3P_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133A_2:214494_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-FOCUS:214494_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133_PLUS_2:214494_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133A:214494_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133_PLUS_2:230884_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133B:230884_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133_PLUS_2:230885_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133B:230885_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133_PLUS_2:235325_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133B:235325_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U95AV2:31673_S_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U95E:74333_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U95E:85222_R_AT spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HU35KSUBC:RC_N79813_AT Spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
U133_X3P:HS2.406971.1.S1_3P_AT Spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U133_PLUS_2:1557409_AT Spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U95B:45086_AT Spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
HG-U95D:84838_AT Spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) hs
MOUSE430_2:1427166_A_AT spastic paraplegia 7 homolog (human) mm
MOE430A:1427166_A_AT spastic paraplegia 7 homolog (human) mm
MOUSE430A_2:1427166_A_AT spastic paraplegia 7 homolog (human) mm
MG-U74BV2:109827_AT spastic paraplegia 7 homolog (human) mm
MG-U74BV2:162776_F_AT spastic paraplegia 7 homolog (human) mm
MOE430B:1441585_AT Spastic paraplegia 7 homolog (human) (Spg7), mRNA mm
MOUSE430_2:1441585_AT Spastic paraplegia 7 homolog (human) (Spg7), mRNA mm
MG-U74BV2:113826_AT Spastic paraplegia 7 homolog (human) (Spg7), mRNA mm
MU19KSUBA:TC19598_AT Spastic paraplegia 7 homolog (human) (Spg7), mRNA mm
MU19KSUBB:TC34201_AT Spastic paraplegia 7 homolog (human) (Spg7), mRNA mm
MU19KSUBB:TC34201_G_AT Spastic paraplegia 7 homolog (human) (Spg7), mRNA mm
RAT230_2:1374839_AT spastic paraplegia 7 homolog (human) rn
RAE230A:1374839_AT spastic paraplegia 7 homolog (human) rn
RAE230B:1395985_AT spastic paraplegia 7 homolog (human) rn
RAT230_2:1395985_AT spastic paraplegia 7 homolog (human) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4222 metalloendopeptidase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_500191 Y38F2AR.7 [Caenorhabditis elegans] gb|AAK68448.2| Hypothetical protein Y38F2AR.7 [Caenorhabditis elegans] 0.0
blast EAL31599 GA15413-PA [Drosophila pseudoobscura] 1.0E-137
blast XP_798395 PREDICTED: similar to Paraplegin (Spastic paraplegia protein 7) [Strongylocentrotus purpuratus] 1.0E-137
blast XP_798395 PREDICTED: similar to Paraplegin (Spastic paraplegia protein 7) [Strongylocentrotus purpuratus] 1.0E-120
blast XP_546777 PREDICTED: similar to Paraplegin (Spastic paraplegia protein 7) [Canis familiaris] 1.0E-120
blast AAK85500 Hypothetical protein Y47C4A.1 [Caenorhabditis elegans] gb|AAN01432.2| Hypothetical protein Y108F1.1 [Caenorhabditis elegans] ref|NP_872265.1| Y108F1.1 [Caenorhabditis elegans] ref|NP_508083.1| Y47C4A.1 [Caenorhabditis elegans] 1.0E-112
Protein Domains
Database ID Description E-Value
Pfam IPR000642 EMBL-EBI Peptidase M41 2.6E-91
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 2.8E-62
Pfam IPR000642 EMBL-EBI Peptidase M41 5.0E-28
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 1.9E-36
Pfam IPR000642 EMBL-EBI Peptidase M41 2.6E-91
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 1.6E-84
Pfam IPR000642 EMBL-EBI Peptidase M41 2.2E-19
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 1.0E-36
Pfam IPR005936 EMBL-EBI Peptidase M41, FtsH 2.3E-8
Pfam IPR000642 EMBL-EBI Peptidase M41 3.2E-27
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 1.9E-36
Pfam IPR000642 EMBL-EBI Peptidase M41 3.2E-27
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 1.9E-36
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 6.1E-25
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000027352 1 33-55
GENEFINDER00000014017 1 33-55
Sequence
Target Sequence 
>C. ELEGANS:176013_S_AT
gtggctccggtgaagaagaacaaacactcaatcagttgctcgtcgaaatggacagaatgg
gttcggggaacggagctgttgttgtgctcgcttccacaaatcgagccgatgtccttgata
aggctctcctgagacccggacgcttcgatcgacacatttcaatcgatttaccgacggttt
tggagcgaaaagacatgttcgagttgtatatgagaaagattaagcttgatcatgctccgc
ag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGGCTCCGGTGAAGAAGAACAAAC 690 491 161 Antisense
AAGAACAAACACTCAATCAGTTGCT 594 149 176 Antisense
CAATCAGTTGCTCGTCGAAATGGAC 374 179 189 Antisense
TGTTGTGCTCGCTTCCACAAATCGA 380 563 240 Antisense
AAATCGAGCCGATGTCCTTGATAAG 352 117 258 Antisense
CCTTGATAAGGCTCTCCTGAGACCC 18 269 273 Antisense
GGACGCTTCGATCGACACATTTCAA 182 523 298 Antisense
ACATTTCAATCGATTTACCGACGGT 310 99 314 Antisense
TCGATTTACCGACGGTTTTGGAGCG 311 599 323 Antisense
GAAAAGACATGTTCGAGTTGTATAT 652 353 347 Antisense
GATTAAGCTTGATCATGCTCCGCAG 666 429 378 Antisense
Sequence Source Affymetrix Proprietary Database