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[175997_s_at]

Description Y105E8B.U /REP_DB=WormBase Gene ID /WP=CE25165 /CHR=1 /FEA=Sanger Annotation /DEF=(HINXTON)
Cluster 6grp_highest_10_10 > 63      6grp_high1_10_10 > 03      4grp_highest_8_8 > 29      4grp_high_8_8 > 07      6grp_highest_nonorm > 50      6grp_total > 35      4grp_total > 05      6grp_highest_sub > Cu      6grp_high1_sub > De      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 672
1 2 3 4 range
A 834
(1.8)
P 		717.9
(-0.8)
P 		617.7
(-3)
P 		887.1
(3)
P 		269
B 687.5
(-1.4)
P 		511.5
(-3)
P 		732.8
(-1)
P 		1183
(3)
P 		672
C 711.9
(-0.3)
P 		550.9
(-3)
P 		784.6
(1)
P 		903.7
(3)
P 		353
avr 744.5
(-0.7) 		593.4
(-3) 		711.7
(-1.2) 		991.3
(3) 		398

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 318
1 2 3 4 5 6 range
A 487.7
(0.1)
P 		603.2
(3)
P 		499.5
(0.4)
P 		500.9
(0.4)
P 		373.5
(-2.8)
P 		363.8
(-3)
P 		239
B 633.2
(2.3)
P 		568.1
(1.1)
P 		670
(3)
P 		352.4
(-3)
P 		374.3
(-2.6)
P 		464.2
(-0.9)
P 		318
C 669.9
(3)
P 		583.6
(1.3)
P 		425.5
(-1.8)
P 		361.6
(-3)
P 		370.3
(-2.8)
P 		551.9
(0.7)
P 		308
avr 596.9
(3) 		585
(2.7) 		531.7
(1.3) 		405
(-2.1) 		372.7
(-3) 		460
(-0.7) 		224
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 177
1 2 3 4 range
A 303.7
(3)
P 		155.8
(-2.1)
P 		161.5
(-1.9)
P 		129.9
(-3)
P 		174
B 219.2
(1.4)
P 		126.3
(-3)
P 		169.8
(-0.9)
P 		252.1
(3)
P 		126
C 235.6
(1.1)
P 		158.4
(-2.7)
P 		273.4
(3)
P 		152.4
(-3)
P 		121
avr 252.8
(3) 		146.8
(-3) 		201.6
(0.1) 		178.1
(-1.2) 		106

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 176
1 2 3 4 5 6 range
A 89.9
(-2.9)
P 		214.5
(3)
P 		108.8
(-2)
P 		127
(-1.2)
P 		112.7
(-1.9)
P 		88.6
(-3)
P 		126
B 220.3
(3)
P 		189.1
(1.5)
P 		162.7
(0.3)
P 		93.3
(-3)
P 		152.1
(-0.2)
P 		173.1
(0.8)
P 		127
C 248.3
(3)
P 		178.1
(0.6)
P 		108.3
(-1.8)
P 		72.7
(-3)
P 		119.8
(-1.4)
P 		184.7
(0.8)
P 		176
avr 186.2
(2.5) 		193.9
(3) 		126.6
(-1.2) 		97.7
(-3) 		128.2
(-1.1) 		148.8
(0.2) 		96
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 175997_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18765
Sequence Type Exemplar sequence
Representative Public ID Y105E8B.U NCBI
Target Description Y105E8B.U /REP_DB=WormBase Gene ID /WP=CE25165 /CHR=1 /FEA=Sanger Annotation /DEF=(HINXTON)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_170951(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_170951 NCBI Caenorhabditis elegans Y105E8A.19 (Y105E8A.19) mRNA, complete cds. 11/11 None
GENEFINDER00000013508 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:14484947:14486651:-1 11/11 None
SNAP00000013344 ENSEMBL cdna:SNAP chromosome:CEL140:I:14485037:14506409:-1 11/11 None
Y105E8A.19 ENSEMBL cdna:known chromosome:CEL140:I:14484792:14494880:-1 gene:Y105E8A.19 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:14484967-14486582(-) 99.28 100.0
Public Domain and Genome References
Gene Title
Ensembl Y105E8A.19
Entrez Gene 173311 Entrez gene
SwissProt Q8WQA5 EMBL-EBI
WormBase CE33722 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:267446_S_AT tRNA synthetase class I (W and Y) family protein at
CANINE:1591677_AT similar to Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) cfa
CANINE_2:CFA.17812.1.S1_S_AT similar to Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) cfa
CANINE_2:CFA.19844.1.S1_AT similar to Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) cfa
CANINE_2:CFAAFFX.16411.1.S1_AT similar to Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) cfa
CANINE_2:CFAAFFX.16428.1.S1_AT similar to Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) cfa
CANINE_2:CFAAFFX.16428.1.S1_S_AT similar to Tyrosyl-tRNA synthetase, cytoplasmic (Tyrosyl--tRNA ligase) (TyrRS) cfa
DROSOPHILA_2:1632234_AT Tyrosyl-tRNA synthetase dm
DROSGENOME1:142649_AT Tyrosyl-tRNA synthetase dm
CHICKEN:GGA.4637.1.S1_S_AT tyrosyl-tRNA synthetase gga
CHICKEN:GGA.4637.2.S1_S_AT tyrosyl-tRNA synthetase gga
HG-U133A_2:212048_S_AT tyrosyl-tRNA synthetase hs
HG-FOCUS:212048_S_AT tyrosyl-tRNA synthetase hs
HG-U133_PLUS_2:212048_S_AT tyrosyl-tRNA synthetase hs
HG-U133A:212048_S_AT tyrosyl-tRNA synthetase hs
HU35KSUBA:AA232121_R_AT tyrosyl-tRNA synthetase hs
HU35KSUBA:AA232121_S_AT tyrosyl-tRNA synthetase hs
HU35KSUBA:RC_AA257977_AT tyrosyl-tRNA synthetase hs
HU35KSUBC:RC_AA102053_AT tyrosyl-tRNA synthetase hs
HUGENEFL:U40714_AT tyrosyl-tRNA synthetase hs
U133_X3P:HS.239307.1.A2_3P_A_AT tyrosyl-tRNA synthetase hs
U133_X3P:HS.168020.0.A1_3P_AT tyrosyl-tRNA synthetase hs
HG-U133_PLUS_2:238760_AT tyrosyl-tRNA synthetase hs
HG-U133B:238760_AT tyrosyl-tRNA synthetase hs
HG-U95AV2:38977_AT tyrosyl-tRNA synthetase hs
HG-U95B:43172_AT tyrosyl-tRNA synthetase hs
HG-U95D:71297_AT Tyrosyl-tRNA synthetase hs
HG-U95E:72663_AT Tyrosyl-tRNA synthetase hs
HG-U95E:84414_AT Tyrosyl-tRNA synthetase hs
HU35KSUBC:RC_AA146671_AT Tyrosyl-tRNA synthetase hs
HU35KSUBD:RC_R06129_AT Tyrosyl-tRNA synthetase hs
MU11KSUBA:AA673272_S_AT tyrosyl-tRNA synthetase mm
MU11KSUBB:MSA.16669.0_S_AT tyrosyl-tRNA synthetase mm
MU11KSUBB:MSA.18695.0_S_AT tyrosyl-tRNA synthetase mm
MG-U74AV2:93564_AT tyrosyl-tRNA synthetase mm
MOE430A:1460638_AT tyrosyl-tRNA synthetase mm
MOUSE430A_2:1460638_AT tyrosyl-tRNA synthetase mm
MOUSE430_2:1460638_AT tyrosyl-tRNA synthetase mm
MG-U74AV2:162093_AT Tyrosyl-tRNA synthetase, mRNA (cDNA clone MGC:37380 IMAGE:4976999) mm
MU11KSUBA:AA492894_AT Tyrosyl-tRNA synthetase, mRNA (cDNA clone MGC:37380 IMAGE:4976999) mm
MU19KSUBA:TC14996_AT Tyrosyl-tRNA synthetase, mRNA (cDNA clone MGC:37380 IMAGE:4976999) mm
MU19KSUBA:TC14996_G_AT Tyrosyl-tRNA synthetase, mRNA (cDNA clone MGC:37380 IMAGE:4976999) mm
MU19KSUBB:TC33433_AT Tyrosyl-tRNA synthetase, mRNA (cDNA clone MGC:37380 IMAGE:4976999) mm
RG-U34C:RC_AI235277_AT tyrosyl-tRNA synthetase (predicted) rn
RAE230A:1372009_AT tyrosyl-tRNA synthetase (predicted) rn
RAT230_2:1372009_AT tyrosyl-tRNA synthetase (predicted) rn
YEAST_2:1774768_AT Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that aminoacylates tRNA(Tyr), required for cytoplasmic protein synthesis, interacts with positions 34 and 35 of the anticodon of tRNATyr Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6418 tRNA aminoacylation for protein translation inferred from electronic annotation QuickGO AmiGO
6437 tyrosyl-tRNA aminoacylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4812 tRNA ligase activity inferred from electronic annotation QuickGO AmiGO
4831 tyrosine-tRNA ligase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAD21668 Hypothetical protein Y105E8A.19 [Caenorhabditis elegans] ref|NP_740947.2| Y105E8A.19 [Caenorhabditis elegans] dbj|BAC76736.1| tyrosyl-tRNA synthetase (cytoplasmic) [Caenorhabditis elegans] 0.0
blast CAE72594 Hypothetical protein CBG19783 [Caenorhabditis briggsae] 0.0
blast BAC76732.1 methionyl-tRNA synthetase (mitochondrial) [Caenorhabditis elegans] 0.0
blast CAD21668 Hypothetical protein Y105E8A.19 [Caenorhabditis elegans] ref|NP_740947.2| Y105E8A.19 [Caenorhabditis elegans] dbj|BAC76736.1| tyrosyl-tRNA synthetase (cytoplasmic) [Caenorhabditis elegans] 1.0E-102
blast CAG32285 hypothetical protein [Gallus gallus] ref|NP_001006314.1| tyrosyl-tRNA synthetase [Gallus gallus] 2.0E-85
Protein Domains
Database ID Description E-Value
Pfam IPR002305 EMBL-EBI Aminoacyl-tRNA synthetase, class Ib 9.8E-56
Pfam IPR002305 EMBL-EBI Aminoacyl-tRNA synthetase, class Ib 9.8E-56
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000013508 1 280-302
Sequence
Target Sequence 
>C. ELEGANS:175997_S_AT
ctcaatggagcagctttgcacatccaacgtgctccggataatggtggtgacgtggaggtc
acaaactacaaacagttggagcaggaatttgtgattggaacgaagaatgagcagcagttt
ccacttcatccggctgatttgaagaacgcggtggttggggttattaatcgaagaaaaaaa
caaaaagcggaaaaattcgacttttcggtgtcaatttttgaatatcaaaaaattcagaaa
attttttcgacaaacctacaaaatacaacatgtagaattctgatgtttcctgtcaaactc
agatttaatttaaattcgacttttgaagcaaaattttggattaaaaaatccctattcgac
ggagttcgagccgatttcgccgaaaagccacgccagaagctcgtgacagatgcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTCAATGGAGCAGCTTTGCACATCC 427 227 397 Antisense
GCAGCTTTGCACATCCAACGTGCTC 237 313 406 Antisense
CACATCCAACGTGCTCCGGATAATG 563 195 415 Antisense
ACGTGCTCCGGATAATGGTGGTGAC 142 93 423 Antisense
GGATAATGGTGGTGACGTGGAGGTC 432 511 432 Antisense
CGTGGAGGTCACAAACTACAAACAG 450 245 447 Antisense
TCATCCGGCTGATTTGAAGAACGCG 204 619 522 Antisense
AGTTCGAGCCGATTTCGCCGAAAAG 434 63 759 Antisense
TCGAGCCGATTTCGCCGAAAAGCCA 358 601 762 Antisense
AAGCCACGCCAGAAGCTCGTGACAG 392 149 781 Antisense
ACGCCAGAAGCTCGTGACAGATGCC 106 91 786 Antisense
Sequence Source Affymetrix Proprietary Database