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[175885_at]

Description F12E12.C /REP_DB=WormBase Gene ID /WP=CE20672 /CHR=2 /FEA=Sanger Annotation /DEF=(ST.LOUIS)
Cluster 6grp_total > 18      4grp_total > 44      6grp_cgc > 11      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 213.8
(3)
P 		192.7
(1.6)
P 		160.8
(-0.5)
P 		123.7
(-3)
A 		90
B 206.8
(3)
P 		183.6
(1.5)
P 		147.9
(-0.7)
A 		111.1
(-3)
A 		96
C 173.7
(1)
P 		202.4
(3)
P 		114.4
(-3)
M 		136.9
(-1.5)
A 		88
avr 198.1
(3) 		192.9
(2.6) 		141
(-1.6) 		123.9
(-3) 		74

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 475
1 2 3 4 5 6 range
A 553.9
(3)
P 		145.3
(-2.3)
P 		88.7
(-3)
P 		91.4
(-3)
A 		111.8
(-2.7)
P 		124.5
(-2.5)
M 		465
B 402.2
(3)
P 		152.9
(-1.6)
P 		157.7
(-1.5)
P 		78.7
(-3)
A 		125.9
(-2.1)
A 		110.4
(-2.4)
P 		324
C 493.1
(3)
P 		175.9
(-1.9)
P 		105
(-3)
P 		108.6
(-2.9)
A 		136.7
(-2.5)
P 		118.8
(-2.8)
P 		388
avr 483.1
(3) 		158
(-2) 		117.1
(-2.6) 		92.9
(-3) 		124.8
(-2.5) 		117.9
(-2.6) 		390
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 60
1 2 3 4 range
A 77.8
(3)
P 		41.8
(-0.6)
P 		42
(-0.6)
P 		18.1
(-3)
A 		60
B 65.9
(3)
P 		45.3
(0.1)
P 		34.3
(-1.5)
A 		23.7
(-3)
A 		42
C 57.5
(2.9)
P 		58.2
(3)
P 		39.9
(-0.1)
M 		23.1
(-3)
A 		35
avr 67.1
(3) 		48.4
(0.5) 		38.7
(-0.7) 		21.6
(-3) 		46

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 164
1 2 3 4 5 6 range
A 102.1
(3)
P 		51.7
(-0.7)
P 		19.3
(-3)
P 		23.2
(-2.7)
A 		33.7
(-2)
P 		30.3
(-2.2)
M 		83
B 140
(3)
P 		50.9
(-1.5)
P 		38.3
(-2.1)
P 		20.9
(-3)
A 		51.2
(-1.5)
A 		41.2
(-2)
P 		119
C 182.8
(3)
P 		53.7
(-1.8)
P 		26.7
(-2.8)
P 		21.8
(-3)
A 		44.2
(-2.2)
P 		39.8
(-2.3)
P 		161
avr 141.6
(3) 		52.1
(-1.5) 		28.1
(-2.7) 		22
(-3) 		43
(-1.9) 		37.1
(-2.2) 		120
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175885_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18896
Sequence Type Exemplar sequence
Representative Public ID F12E12.C NCBI
Target Description F12E12.C /REP_DB=WormBase Gene ID /WP=CE20672 /CHR=2 /FEA=Sanger Annotation /DEF=(ST.LOUIS)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_062239(10)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_062239 NCBI Caenorhabditis elegans F12E12.7 (F12E12.7) mRNA, complete cds. 10/11 A 
SNAP00000025174 ENSEMBL cdna:SNAP chromosome:CEL140:II:3742517:3743770:-1 11/11 None
GENEFINDER00000025185 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:3742517:3743770:-1 11/11 None
F12E12.7 ENSEMBL cdna:known chromosome:CEL140:II:3742517:3752272:-1 gene:F12E12.7 10/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000025175 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:3742515-3744370(-) 99.9 100.0
Public Domain and Genome References
Gene Title
Gene Symbol sdz-11
Ensembl F12E12.7
Entrez Gene 173719 Entrez gene
SwissProt Q9BLB8 EMBL-EBI
WormBase CE26808 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK18930 Hypothetical protein F12E12.7 [Caenorhabditis elegans] ref|NP_494640.1| F12E12.7 [Caenorhabditis elegans] 0.0
blast AAK18930 Hypothetical protein F12E12.7 [Caenorhabditis elegans] ref|NP_494640.1| F12E12.7 [Caenorhabditis elegans] 1.0E-144
blast CAB05801 Hypothetical protein F26D2.15 [Caenorhabditis elegans] emb|CAB04187.1| Hypothetical protein F26D2.15 [Caenorhabditis elegans] ref|NP_507157.1| F26D2.15 [Caenorhabditis elegans] 1.0E-116
blast NP_503752 DeHydrogenases, Short chain family member (dhs-14) [Caenorhabditis elegans] gb|AAF39953.1| Dehydrogenases, short chain protein 14 [Caenorhabditis elegans] 1.0E-115
blast CAB05801 Hypothetical protein F26D2.15 [Caenorhabditis elegans] emb|CAB04187.1| Hypothetical protein F26D2.15 [Caenorhabditis elegans] ref|NP_507157.1| F26D2.15 [Caenorhabditis elegans] 1.0E-105
Protein Domains
Database ID Description E-Value
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 5.0E-12
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 6.0E-17
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 2.7E-47
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 5.5E-58
Sequence
Target Sequence 
>C. ELEGANS:175885_AT
gactcttcagaagttcggacgtcttgatatccttgtgaataatgccggagcagctgtaaa
cgatcctcaaggacggatgggcattgatcagcaaattgaagatttcgataagactttcca
aattaatatgcgaagtgtggtgacgttggtgcagaaggccaaggagcacttgatcaagac
caagggggaaattatcaatgtttctagtattggtggaggaccccacgctcaacccgatat
gatgtactacggaatgtccaaagctgctcttgatcagttcacaagaagcactgcaatcac
gctgattcaacacggagtccgtgtgaactcggtgagcccgggaggagtctacacaggatt
cggagaggctatgggattcccaccaggtgctcttgagaagatcatgaaatacttcgagtc
ccacaaggaatgtgtcccatgcggtcatatggctcagcccatagaaattgcccaagtcat
cgcgtttttggcggaccgtaccatgtcttcatacatcattggacagtcgatcatcgccga
tggaggatcctcgctgttga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GACTCTTCAGAAGTTCGGACGTCTT 203 369 396 Antisense
GCAGCTGTAAACGATCCTCAAGGAC 611 313 445 Antisense
AGTATTGGTGGAGGACCCCACGCTC 272 63 601 Antisense
CCACGCTCAACCCGATATGATGTAC 707 273 618 Antisense
ATCACGCTGATTCAACACGGAGTCC 501 27 691 Antisense
GGGAGGAGTCTACACAGGATTCGGA 618 495 735 Antisense
TTCCCACCAGGTGCTCTTGAGAAGA 147 697 772 Antisense
GCTCAGCCCATAGAAATTGCCCAAG 448 301 847 Antisense
TTGCCCAAGTCATCGCGTTTTTGGC 53 701 863 Antisense
TGGACAGTCGATCATCGCCGATGGA 248 547 915 Antisense
GCCGATGGAGGATCCTCGCTGTTGA 104 285 931 Antisense
Sequence Source Affymetrix Proprietary Database