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[175845_at] programmed cell death activator (egl-1)

Description g3133314 /REP_DB=GenBank Identifier /GB=AF057309.1 /PROTEIN_GB=AAC39023.1 /CHR=5 /FEA=Mapped Transcript /DEF=programmed cell death activator EGL-1
Cluster 6grp_total > 76      4grp_total > 39      6grp_cgc > 57      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 67
1 2 3 4 range
A 52.3
(-2.7)
A 		51.4
(-3)
A 		69.7
(2.5)
A 		71.4
(3)
A 		20
B 58.3
(3)
P 		30.5
(-1.3)
A 		19.2
(-3)
A 		51.9
(2)
A 		39
C 45.3
(3)
M 		36.6
(1.7)
A 		31.2
(0.9)
A 		4.5
(-3)
A 		41
avr 52
(3) 		39.5
(-3) 		40
(-2.8) 		42.6
(-1.5) 		13

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 77
1 2 3 4 5 6 range
A 54.5
(2.5)
P 		47.5
(1.8)
A 		44.1
(1.4)
A 		2.8
(-3)
A 		29.9
(-0.1)
A 		59.1
(3)
P 		56
B 33.7
(-2.9)
P 		45.6
(-1.1)
P 		66.8
(1.9)
M 		74.3
(3)
P 		32.7
(-3)
A 		66.3
(1.8)
P 		42
C 2.6
(-3)
A 		53.7
(1)
P 		30.7
(-0.8)
A 		69
(2.1)
A 		71.6
(2.3)
A 		80
(3)
P 		77
avr 30.3
(-3) 		48.9
(-0.1) 		47.2
(-0.3) 		48.7
(-0.1) 		44.7
(-0.7) 		68.5
(3) 		38
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 18
1 2 3 4 range
A 19
(3)
A 		11.2
(-2.5)
A 		18.2
(2.4)
A 		10.5
(-3)
A 		9
B 18.6
(3)
P 		7.5
(-1.7)
A 		4.4
(-3)
A 		11.1
(-0.2)
A 		14
C 15
(3)
M 		10.5
(1.1)
A 		10.9
(1.3)
A 		0.8
(-3)
A 		14
avr 17.5
(3) 		9.7
(-1.7) 		11.2
(-0.8) 		7.5
(-3) 		10

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 10.1
(0.5)
P 		16.9
(3)
A 		9.6
(0.3)
A 		0.7
(-3)
A 		9
(0.1)
A 		14.4
(2.1)
P 		16
B 11.7
(-3)
P 		15.2
(-1.4)
P 		16.2
(-0.9)
M 		19.7
(0.7)
P 		13.3
(-2.3)
A 		24.7
(3)
P 		13
C 1
(-3)
A 		16.4
(0.6)
P 		7.8
(-1.4)
A 		13.9
(0)
A 		23.2
(2.2)
A 		26.8
(3)
P 		26
avr 7.6
(-3) 		16.2
(0.6) 		11.2
(-1.5) 		11.4
(-1.4) 		15.2
(0.2) 		22
(3) 		14
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175845_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19934
Sequence Type Exemplar sequence
Representative Public ID 3133314 NCBI
Target Description g3133314 /REP_DB=GenBank Identifier /GB=AF057309.1 /PROTEIN_GB=AAC39023.1 /CHR=5 /FEA=Mapped Transcript /DEF=programmed cell death activator EGL-1
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074174(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074174 NCBI Caenorhabditis elegans EGg Laying defective family member (egl-1) (egl-1) mRNA, complete cds. 11/11 None
F23B12.9 ENSEMBL cdna:known chromosome:CEL140:V:14433898:14434947:-1 gene:F23B12.9 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000025800 6/11 Cross Hyb Matching Probes None
GENEFINDER00000025811 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:14433897-14434947(-) 100.0 100.0
Public Domain and Genome References
Gene Title programmed cell death activator (egl-1)
Gene Symbol egl-1
Ensembl F23B12.9
Entrez Gene 179943 Entrez gene
SwissProt O61667 EMBL-EBI
WormBase CE35714 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5515 protein binding inferred from physical interaction QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB82213 Hypothetical protein F23B12.9 [Caenorhabditis elegans] ref|NP_506575.2| EGg Laying defective family member (egl-1) [Caenorhabditis elegans] sp|O61667|EGL1_CAEEL Programmed cell death activator egl-1 (Egg laying defective protein 1) 3.0E-37
blast AAC39023 programmed cell death activator EGL-1 [Caenorhabditis elegans] 4.0E-29
blast 1TY4 Chain , Crystal Structure Of A Ced-9EGL-1 Complex pdb|1TY4|C Chain C, Crystal Structure Of A Ced-9EGL-1 Complex 3.0E-13
Sequence
Target Sequence 
>C. ELEGANS:175845_AT
agtcgtattctaacttctcttttcaattcagttgatatgctgatgctcacctttgcctca
acctcttcggatcttctaccaatgtccaacgtttttgacgttcaatcttccgttttctac
aacgaaaagaacatgttctactcctcgtctcaggacttctcctcgtgtgaagattcttct
caatttgccgacgactcgggattttttgatgactctgagatcagcagcatcggctacgag
atcggctccaagctagcagcaatgtgcgatgacttcgatgctcagatgatgtcctactcg
gcccatgcttccgacagaagcctcttccatcgtcttctggactttttcgctttttaagtg
atcaaaatctccaacttttctccaatttgtaccatgatttctcataatacccggtgtttt
ttcttcatttgtgattatttttcgatctctccgtctccaactcccctcaatatttgtacc
atagtcctttattgctcat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGTCGTATTCTAACTTCTCTTTTCA 143 61 41 Antisense
TTGATATGCTGATGCTCACCTTTGC 672 705 72 Antisense
GATCTTCTACCAATGTCCAACGTTT 8 419 110 Antisense
TGACGTTCAATCTTCCGTTTTCTAC 249 571 136 Antisense
ATTCTTCTCAATTTGCCGACGACTC 501 11 213 Antisense
AGCAGCATCGGCTACGAGATCGGCT 602 77 263 Antisense
GATGCTCAGATGATGTCCTACTCGG 358 413 317 Antisense
TCCATCGTCTTCTGGACTTTTTCGC 204 585 366 Antisense
CAAAATCTCCAACTTTTCTCCAATT 679 189 403 Antisense
TCCAACTCCCCTCAATATTTGTACC 702 585 496 Antisense
TGTACCATAGTCCTTTATTGCTCAT 465 559 515 Antisense
Sequence Source GenBank