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[175812_at]

Description g6969623 /REP_DB=GenBank Identifier /GB=AF226866.1 /PROTEIN_GB=AAF33845.1 /CHR=4 /FEA=Mapped Transcript /DEF=cell-corpse engulfment protein CED-2
Cluster 6grp_highest_10_10 > 98      6grp_high1_10_10 > 89      4grp_highest_8_8 > 30      4grp_high_8_8 > 04      6grp_highest_nonorm > 96      6grp_total > 99      4grp_total > 05      6grp_highest_sub > Cu      6grp_cgc > 79      6grp_high1_sub > Cu      6grp_cgc_sub > Da      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 761
1 2 3 4 range
A 705.1
(0.5)
P
472.9
(-3)
P
595.7
(-1.2)
P
874.1
(3)
P
401
B 756.6
(0.1)
P
546.8
(-3)
P
651.9
(-1.5)
P
957
(3)
P
410
C 703.7
(-1.6)
P
689.8
(-1.8)
P
548.7
(-3)
P
1233.8
(3)
P
685
avr 721.8
(-1)
569.8
(-3)
598.8
(-2.6)
1021.6
(3)
452

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 945
1 2 3 4 5 6 range
A 782.8
(-1)
P
509.7
(-3)
P
511.2
(-3)
P
614.6
(-2.2)
P
1298.3
(2.9)
P
1316.7
(3)
P
807
B 703.3
(-0.6)
P
457
(-2.5)
P
398.2
(-3)
P
800.4
(0.1)
P
1170.8
(3)
P
1072
(2.2)
P
773
C 661.9
(-2.1)
P
589.6
(-2.6)
P
539.8
(-3)
P
535.6
(-3)
P
921.8
(-0.1)
P
1343.6
(3)
P
808
avr 716
(-1.2)
518.8
(-2.7)
483.1
(-3)
650.2
(-1.7)
1130.3
(2.1)
1244.1
(3)
761
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 154
1 2 3 4 range
A 256.7
(3)
P
102.6
(-3)
P
155.7
(-0.9)
P
128
(-2)
P
154
B 241.3
(3)
P
135
(-3)
P
151.1
(-2.1)
P
203.9
(0.9)
P
106
C 233
(3)
P
198.3
(-2)
P
191.2
(-3)
P
208
(-0.6)
P
42
avr 243.7
(3)
145.3
(-3)
166
(-1.7)
180
(-0.9)
98

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 379
1 2 3 4 5 6 range
A 144.3
(-2.3)
P
181.3
(-1.5)
P
111.3
(-3)
P
155.9
(-2)
P
391.8
(3)
P
320.6
(1.5)
P
281
B 244.7
(-0.7)
P
152.1
(-2.1)
P
96.7
(-3)
P
212
(-1.2)
P
475.7
(3)
P
399.8
(1.8)
P
379
C 245.4
(-0.6)
P
179.9
(-1.7)
P
137.4
(-2.5)
P
107.7
(-3)
P
298.3
(0.3)
P
449.8
(3)
P
342
avr 211.5
(-0.9)
171.1
(-1.8)
115.1
(-3)
158.5
(-2.1)
388.6
(3)
390.1
(3)
275
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175812_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19888
Sequence Type Exemplar sequence
Representative Public ID 6969623 NCBI
Target Description g6969623 /REP_DB=GenBank Identifier /GB=AF226866.1 /PROTEIN_GB=AAF33845.1 /CHR=4 /FEA=Mapped Transcript /DEF=cell-corpse engulfment protein CED-2
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067704(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_067704 NCBI Caenorhabditis elegans CEll Death abnormality family member (ced-2) (ced-2) mRNA, complete cds. 11/11 A 
Y41D4B.13 ENSEMBL cdna:known chromosome:CEL140:IV:1597314:1601619:1 gene:Y41D4B.13 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:1597319-1601625(+) 100.0 100.0
Public Domain and Genome References
Gene Title
Gene Symbol ced-2
Ensembl Y41D4B.13
Entrez Gene 176968 Entrez gene
SwissProt Q9NHC3 EMBL-EBI
WormBase CE28360 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.23374.1.S1_AT similar to Crk-like protein cfa
CANINE_2:CFAAFFX.23379.1.S1_AT similar to Crk-like protein cfa
CANINE_2:CFAAFFX.23379.1.S1_S_AT similar to Crk-like protein cfa
DROSOPHILA_2:1634217_S_AT dm
DROSGENOME1:153622_AT dm
CHICKEN:GGAAFFX.3975.1.S1_AT similar to v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk avian sarcoma virus CT10 oncogene homolog-like gga
CHICKEN:GGAAFFX.3975.2.S1_AT similar to v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk avian sarcoma virus CT10 oncogene homolog-like gga
CHICKEN:GGAAFFX.3975.2.S1_S_AT similar to v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk avian sarcoma virus CT10 oncogene homolog-like gga
HG-U95AV2:415_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HC-G110:415_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-U95AV2:33524_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-U133_PLUS_2:206184_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-U133A:206184_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-FOCUS:206184_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-U133A_2:206184_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HU35KSUBA:AA393961_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HU35KSUBB:RC_N33290_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HUGENEFL:X59656_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
U133_X3P:G4885152_3P_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
U133_X3P:HS.5613.0.S1_3P_X_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
U133_X3P:HS.5613.0.S1_3P_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-U133A_2:212180_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-U133_PLUS_2:212180_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-U133A:212180_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HG-U95AV2:35301_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
HU35KSUBC:RC_D20322_AT V-crk sarcoma virus CT10 oncogene homolog (avian)-like hs
MOE430A:1425604_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOUSE430A_2:1425604_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOUSE430_2:1425604_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MU11KSUBB:MSA.2646.0_S_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MG-U74AV2:103849_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOUSE430_2:1421953_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOE430A:1421953_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOUSE430A_2:1421953_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MG-U74AV2:103848_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOE430A:1436950_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOUSE430A_2:1436950_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOUSE430_2:1436950_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOE430A:1421954_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOUSE430A_2:1421954_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MOUSE430_2:1421954_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like mm
MU19KSUBB:TC31192_AT V-crk sarcoma virus CT10 oncogene homolog (avian)-like, mRNA (cDNA clone IMAGE:5355496) mm
RAE230B:1395605_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like (predicted) rn
RAT230_2:1395605_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like (predicted) rn
RAE230B:1393942_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like (predicted) rn
RAT230_2:1393942_AT v-crk sarcoma virus CT10 oncogene homolog (avian)-like (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5070 SH3/SH2 adaptor activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAK68463 Cell death abnormality protein 2 [Caenorhabditis elegans] ref|NP_500105.1| CEll Death abnormality family member (ced-2) [Caenorhabditis elegans] gb|AAF33845.1| cell-corpse engulfment protein CED-2 [Caenorhabditis elegans] 1.0E-149
blast CAE67964 Hypothetical protein CBG13568 [Caenorhabditis briggsae] 1.0E-123
blast XP_393082 PREDICTED: similar to ENSANGP00000010943 [Apis mellifera] 1.0E-34
Protein Domains
Database ID Description E-Value
Pfam IPR000980 EMBL-EBI SH2 motif 3.0E-20
Pfam IPR001452 EMBL-EBI SH3 1.5E-17
Sequence
Target Sequence
>C. ELEGANS:175812_AT
attcaccgccgtcagcgaataaaatcgttttttttttctaaatttttaaccttgaaattt
attgattcgcttgcccctccaccagttttcctctaatacattacagctttaccatagaaa
aaaatcgtttttttttccaaattatatttataatgatatcatgcacaattttcgttgcct
tttccgcccaccgaaccccaattcgtgtccattccattttgttcacttt


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
ATTCACCGCCGTCAGCGAATAAAAT 648 5 835 Antisense
GCCGTCAGCGAATAAAATCGTTTTT 435 263 842 Antisense
GAAATTTATTGATTCGCTTGCCCCT 268 363 888 Antisense
TCCACCAGTTTTCCTCTAATACATT 107 589 912 Antisense
ACCAGTTTTCCTCTAATACATTACA 628 85 915 Antisense
GTTTTCCTCTAATACATTACAGCTT 671 447 919 Antisense
TAATACATTACAGCTTTACCATAGA 72 633 928 Antisense
TATCATGCACAATTTTCGTTGCCTT 591 659 991 Antisense
TCATGCACAATTTTCGTTGCCTTTT 444 621 993 Antisense
TTCGTGTCCATTCCATTTTGTTCAC 367 695 1036 Antisense
GTGTCCATTCCATTTTGTTCACTTT 244 487 1039 Antisense
Sequence Source GenBank