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[175780_at]

Description g1778589 /REP_DB=GenBank Identifier /GB=U82935.1 /PROTEIN_GB=AAB40868.1 /CHR=X /FEA=Mapped Transcript /DEF=protein kinase C2 A isoform
Cluster 6grp_highest_10_10 > 40      6grp_high1_10_10 > 05      4grp_highest_8_8 > 51      4grp_high_8_8 > 32      6grp_highest_nonorm > 70      6grp_total > 15      4grp_total > 47      6grp_highest_sub > De      6grp_cgc > 22      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 486
1 2 3 4 range
A 722.3
(3)
P
246.2
(-3)
P
251.1
(-2.9)
P
251.3
(-2.9)
P
476
B 671.4
(3)
P
247.5
(-2.8)
P
236.1
(-3)
P
330.7
(-1.7)
P
435
C 692.7
(3)
P
339.3
(-1.9)
P
287.2
(-2.6)
P
256.8
(-3)
P
436
avr 695.5
(3)
277.7
(-2.7)
258.1
(-3)
279.6
(-2.7)
437

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 385
1 2 3 4 5 6 range
A 476.8
(3)
P
337.1
(0.3)
P
333.8
(0.2)
P
204.1
(-2.3)
P
296.9
(-0.5)
P
166.5
(-3)
P
310
B 532.1
(3)
P
424.3
(1.2)
P
290.7
(-1.1)
P
252.1
(-1.7)
P
196.8
(-2.6)
P
174.8
(-3)
P
357
C 539.9
(3)
P
432.8
(1.3)
P
202.4
(-2.3)
P
279
(-1.1)
P
155.8
(-3)
P
154.6
(-3)
P
385
avr 516.3
(3)
398.1
(1)
275.6
(-1.1)
245.1
(-1.6)
216.5
(-2.1)
165.3
(-3)
351
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 226
1 2 3 4 range
A 263
(3)
P
53.4
(-2.6)
P
65.6
(-2.2)
P
36.8
(-3)
P
226
B 214.1
(3)
P
61.1
(-2.8)
P
54.7
(-3)
P
70.5
(-2.4)
P
159
C 229.3
(3)
P
97.5
(-1.3)
P
100.1
(-1.2)
P
43.3
(-3)
P
186
avr 235.5
(3)
70.7
(-2.3)
73.5
(-2.2)
50.2
(-3)
185

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 160
1 2 3 4 5 6 range
A 87.9
(0.6)
P
119.9
(3)
P
72.7
(-0.6)
P
51.8
(-2.1)
P
89.6
(0.7)
P
40.5
(-3)
P
79
B 185.1
(3)
P
141.2
(0.8)
P
70.6
(-2.7)
P
66.8
(-2.9)
P
80
(-2.3)
P
65.2
(-3)
P
120
C 200.1
(3)
P
132.1
(0.3)
P
51.5
(-3)
P
56.1
(-2.8)
P
50.4
(-3)
P
51.8
(-2.9)
P
150
avr 157.7
(3)
131.1
(1.5)
64.9
(-2.3)
58.2
(-2.7)
73.3
(-1.8)
52.5
(-3)
105
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175780_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19983
Sequence Type Exemplar sequence
Representative Public ID 1778589 NCBI
Target Description g1778589 /REP_DB=GenBank Identifier /GB=U82935.1 /PROTEIN_GB=AAB40868.1 /CHR=X /FEA=Mapped Transcript /DEF=protein kinase C2 A isoform
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029345(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_001029345 NCBI Caenorhabditis elegans Protein Kinase C family member (pkc-2) (pkc-2) mRNA, complete cds. 11/11 None
E01H11.1a.2 ENSEMBL cdna:known chromosome:CEL140:X:9371060:9385965:1 gene:E01H11.1 11/11 A 
E01H11.1a.1 ENSEMBL cdna:known chromosome:CEL140:X:9371086:9386328:1 gene:E01H11.1 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
NM_001029347 1/11 Cross Hyb Matching Probes None
E01H11.1c 1/11 Cross Hyb Matching Probes A 
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
181166 3 1 NM_001029345 175780_at (11), 175781_s_at (11)
NM_001029346 175779_at (11), 192006_s_at (11)
NM_001029347 175781_s_at (11), 186204_at (11), 192005_at (11), 192006_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:9371059-9385965(+) 100.0 100.0
Public Domain and Genome References
Ensembl E01H11.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAM51503 Protein kinase c protein 2, isoform a [Caenorhabditis elegans] ref|NP_001024516.1| Protein Kinase C family member (pkc-2) [Caenorhabditis elegans] 0.0
blast AAB40868 protein kinase C2 A isoform [Caenorhabditis elegans] 0.0
blast AAM51504 Protein kinase c protein 2, isoform b [Caenorhabditis elegans] ref|NP_001024517.1| Protein Kinase C family member (pkc-2) [Caenorhabditis elegans] sp|P90980|KPC2_CAEEL Protein kinase C-like 2 (PKC2) 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-68
hanks 1.2.3 AGC group; AGC I Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family; DPKC53b 1.0E-125
Protein Domains
Database ID Description E-Value
Pfam IPR000008 EMBL-EBI C2 domain 1.6E-37
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 2.0E-24
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 6.2E-24
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-81
Pfam IPR000961 EMBL-EBI Protein kinase C-terminal domain 2.2E-35
Sequence
Target Sequence
>C. ELEGANS:175780_AT
aagccaaaactgaaatccgccgatgatacttccaacttcgattcagagtttactcacgag
gtccctaagcttactccgattgaccgtctattcctcatgaatctggatcaaactgaattc
gaaggattctcttttgtcaacccagaatatgttcaagagtgctaaaattctcaaattaat
ttattaaaaactatttagataataatctcattcaccgaaattttaatattctccgaagcc
tctcatgccggagtgactgtgctaaattttgttttgcagcaaattgtaccgatgttacgt
cactagtccactttcttcactttttacattccgtgttagaacattaaacattttcatgca
cttattctaaatgcgtcctttatttgctttttattatattcgaaaattgcaatttgtata
ataagtatgtcatttctgtaccag


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
AAGCCAAAACTGAAATCCGCCGATG 396 147 1917 Antisense
GATAATAATCTCATTCACCGAAATT 279 423 2114 Antisense
TTTAATATTCTCCGAAGCCTCTCAT 163 673 2138 Antisense
CTCTCATGCCGGAGTGACTGTGCTA 81 231 2156 Antisense
GTGACTGTGCTAAATTTTGTTTTGC 363 483 2169 Antisense
TACCGATGTTACGTCACTAGTCCAC 453 649 2203 Antisense
CACTTTCTTCACTTTTTACATTCCG 207 197 2225 Antisense
TAAACATTTTCATGCACTTATTCTA 125 641 2261 Antisense
GCACTTATTCTAAATGCGTCCTTTA 642 315 2274 Antisense
AATGCGTCCTTTATTTGCTTTTTAT 436 165 2286 Antisense
AATAAGTATGTCATTTCTGTACCAG 628 169 2336 Antisense
Sequence Source GenBank