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[175779_at]

Description g1778591 /REP_DB=GenBank Identifier /GB=U82936.1 /PROTEIN_GB=AAB40869.1 /CHR=X /FEA=Mapped Transcript /DEF=protein kinase C2 B isoform
Cluster 6grp_highest_10_10 > 79      6grp_high1_10_10 > 88      4grp_high_8_8 > 61      6grp_highest_nonorm > 90      6grp_total > 88      4grp_total > 60      6grp_highest_sub > In      6grp_cgc > 58      6grp_high1_sub > Da      6grp_cgc_sub > In      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 77
1 2 3 4 range
A 144.2
(3)
P 		124.2
(1.4)
P 		130.7
(1.9)
P 		67.7
(-3)
A 		77
B 117.3
(-3)
P 		132.4
(0.9)
P 		140.5
(3)
P 		134.9
(1.6)
P 		23
C 131.2
(0.8)
P 		144.5
(3)
P 		142.6
(2.7)
P 		107.7
(-3)
P 		37
avr 130.9
(1.8) 		133.7
(2.3) 		137.9
(3) 		103.4
(-3) 		35

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 137
1 2 3 4 5 6 range
A 104.7
(-2.6)
P 		116.3
(-2.1)
P 		206.8
(1.9)
P 		94.7
(-3)
P 		231.3
(3)
P 		174.9
(0.5)
P 		137
B 128.2
(-2.7)
P 		149.2
(-0.9)
P 		124.4
(-3)
P 		147.8
(-1)
P 		143.3
(-1.4)
P 		195
(3)
P 		71
C 112.5
(-2.8)
P 		136.4
(-1.1)
P 		109.7
(-3)
P 		139.6
(-0.9)
P 		125.5
(-1.9)
P 		194.7
(3)
P 		85
avr 115.1
(-3) 		134
(-1.4) 		147
(-0.4) 		127.4
(-2) 		166.7
(1.2) 		188.2
(3) 		73
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 43
1 2 3 4 range
A 52.5
(3)
P 		27
(-0.6)
P 		34.2
(0.4)
P 		9.9
(-3)
A 		43
B 37.4
(3)
P 		32.7
(-0.2)
P 		32.5
(-0.4)
P 		28.7
(-3)
P 		9
C 43.4
(1.8)
P 		41.5
(1.4)
P 		49.7
(3)
P 		18.2
(-3)
P 		32
avr 44.4
(3) 		33.7
(0.5) 		38.8
(1.7) 		18.9
(-3) 		26

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 53
1 2 3 4 5 6 range
A 19.3
(-3)
P 		41.4
(-0.4)
P 		45
(0.1)
P 		24
(-2.4)
P 		69.8
(3)
P 		42.6
(-0.2)
P 		51
B 44.6
(-1)
P 		49.7
(-0.2)
P 		30.2
(-3)
P 		39.1
(-1.7)
P 		58.2
(1)
P 		72.7
(3)
P 		43
C 41.7
(-0.8)
P 		41.6
(-0.8)
P 		27.9
(-3)
P 		28.1
(-3)
P 		40.6
(-1)
P 		65.2
(3)
P 		37
avr 35.2
(-2) 		44.2
(-0.2) 		34.4
(-2.2) 		30.4
(-3) 		56.2
(2.2) 		60.2
(3) 		30
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175779_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19996
Sequence Type Exemplar sequence
Representative Public ID 1778591 NCBI
Target Description g1778591 /REP_DB=GenBank Identifier /GB=U82936.1 /PROTEIN_GB=AAB40869.1 /CHR=X /FEA=Mapped Transcript /DEF=protein kinase C2 B isoform
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001029346(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001029346 NCBI Caenorhabditis elegans Protein Kinase C family member (pkc-2) (pkc-2) mRNA, complete cds. 11/11 None
E01H11.1b ENSEMBL cdna:known chromosome:CEL140:X:9371060:9383841:1 gene:E01H11.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
181166 3 1 NM_001029345 175780_at (11), 175781_s_at (11)
NM_001029346 175779_at (11), 192006_s_at (11)
NM_001029347 175781_s_at (11), 186204_at (11), 192005_at (11), 192006_s_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:9371059-9383841(+) 100.0 100.0
Public Domain and Genome References
Ensembl E01H11.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAM51504 Protein kinase c protein 2, isoform b [Caenorhabditis elegans] ref|NP_001024517.1| Protein Kinase C family member (pkc-2) [Caenorhabditis elegans] sp|P90980|KPC2_CAEEL Protein kinase C-like 2 (PKC2) 0.0
blast AAB40869 protein kinase C2 B isoform [Caenorhabditis elegans] 0.0
blast T15903 protein kinase C homolog - Caenorhabditis elegans 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-68
hanks 1.2.3 AGC group; AGC I Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family; DPKC53b 1.0E-125
Protein Domains
Database ID Description E-Value
Pfam IPR000008 EMBL-EBI C2 domain 1.6E-37
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 2.0E-24
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 6.2E-24
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-81
Pfam IPR000961 EMBL-EBI Protein kinase C-terminal domain 2.7E-21
Sequence
Target Sequence 
>C. ELEGANS:175779_AT
gtagaaccgtgatcatattatttttaattatttcttctcctggtattctatatataaata
ctaaccctcttctaattaacatttcactgtttttcatttgtatccagtttcattgtaaac
attttcacaatatatgtagtttattatcgtctgtccgttggtaaatttttgaatttcaca
actaagaaagcgttataaggaaagatgtttttgtggattgaatcttttgattcaagtgga
ttttgattgttctgtttttcga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTAGAACCGTGATCATATTATTTTT 528 457 2076 Antisense
TTTTAATTATTTCTTCTCCTGGTAT 170 675 2097 Antisense
TTCTTCTCCTGGTATTCTATATATA 81 691 2107 Antisense
ATATAAATACTAACCCTCTTCTAAT 49 15 2127 Antisense
ACCCTCTTCTAATTAACATTTCACT 375 89 2139 Antisense
ATTTCACTGTTTTTCATTTGTATCC 702 15 2156 Antisense
TTCATTTGTATCCAGTTTCATTGTA 433 689 2168 Antisense
ATGTAGTTTATTATCGTCTGTCCGT 505 47 2209 Antisense
TCGTCTGTCCGTTGGTAAATTTTTG 385 605 2222 Antisense
GATGTTTTTGTGGATTGAATCTTTT 67 409 2279 Antisense
GGATTTTGATTGTTCTGTTTTTCGA 523 509 2313 Antisense
Sequence Source GenBank