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[175773_at] MULTIPLE EXOSTOSES HOMOLOG 1

Description g2058696 /REP_DB=GenBank Identifier /GB=U94834.1 /PROTEIN_GB=AAC47509.1 /CHR=4 /FEA=Mapped Transcript /DEF=multiple exostoses homolog 1
Cluster 6grp_highest_10_10 > 97      6grp_high1_10_10 > 69      4grp_highest_8_8 > 60      4grp_high_8_8 > 25      6grp_highest_nonorm > 83      6grp_total > 69      4grp_total > 38      6grp_highest_sub > Cu      6grp_cgc > 29      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 202
1 2 3 4 range
A 448.3
(3)
P 		365.9
(-2.2)
P 		352.6
(-3)
P 		377.8
(-1.4)
P 		96
B 433.5
(3)
P 		349
(-0.6)
P 		291.9
(-3)
P 		431.6
(2.9)
P 		142
C 493.9
(3)
P 		395.6
(-1.8)
P 		373.4
(-2.9)
P 		371.8
(-3)
P 		122
avr 458.6
(3) 		370.2
(-1.4) 		339.3
(-3) 		393.7
(-0.3) 		119

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 295
1 2 3 4 5 6 range
A 428.5
(0.4)
P 		365
(-1.2)
P 		291.3
(-3)
P 		390.3
(-0.5)
P 		454.3
(1.1)
P 		532.1
(3)
P 		241
B 385.9
(-0.3)
P 		411.4
(0.3)
P 		256.4
(-3)
P 		377
(-0.5)
P 		460.5
(1.3)
P 		541.5
(3)
P 		285
C 374.8
(-1.5)
P 		390
(-1.1)
P 		315.1
(-3)
P 		411.9
(-0.5)
P 		427.8
(-0.1)
P 		551.7
(3)
P 		237
avr 396.4
(-0.4) 		388.8
(-0.6) 		287.6
(-3) 		393.1
(-0.5) 		447.5
(0.8) 		541.8
(3) 		254
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 108
1 2 3 4 range
A 163.2
(3)
P 		79.4
(-1.7)
P 		92.2
(-0.9)
P 		55.3
(-3)
P 		108
B 138.2
(3)
P 		86.2
(-1.4)
P 		67.6
(-3)
P 		92
(-0.9)
P 		71
C 163.5
(3)
P 		113.7
(0)
P 		130.1
(1)
P 		62.7
(-3)
P 		101
avr 155
(3) 		93.1
(-1.4) 		96.6
(-1.1) 		70
(-3) 		85

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 140
1 2 3 4 5 6 range
A 79
(-1.7)
P 		129.8
(2.4)
P 		63.4
(-3)
P 		99
(-0.1)
P 		137.1
(3)
P 		129.6
(2.4)
P 		74
B 134.3
(0.1)
P 		136.9
(0.2)
P 		62.3
(-3)
P 		99.8
(-1.4)
P 		187.1
(2.4)
P 		201.9
(3)
P 		140
C 138.9
(0.4)
P 		119
(-0.8)
P 		80.2
(-3)
P 		82.8
(-2.9)
P 		138.4
(0.3)
P 		184.7
(3)
P 		105
avr 117.4
(-0.2) 		128.6
(0.5) 		68.6
(-3) 		93.9
(-1.5) 		154.2
(2) 		172.1
(3) 		104
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 175773_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.19851
Sequence Type Exemplar sequence
Representative Public ID 2058696 NCBI
Target Description g2058696 /REP_DB=GenBank Identifier /GB=U94834.1 /PROTEIN_GB=AAC47509.1 /CHR=4 /FEA=Mapped Transcript /DEF=multiple exostoses homolog 1
Cluster Evidence This cluster is supported by a Mapped Transcript.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069779(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069779 NCBI Caenorhabditis elegans related to mammalian RIB-affecting EXT gene family member (rib-1) (rib-1) mRNA, complete cds. 11/11 A 
F12F6.3.3 ENSEMBL cdna:known chromosome:CEL140:IV:11578727:11583890:1 gene:F12F6.3 11/11 None
F12F6.3.2 ENSEMBL cdna:known chromosome:CEL140:IV:11578761:11583890:1 gene:F12F6.3 11/11 None
F12F6.3.1 ENSEMBL cdna:known chromosome:CEL140:IV:11578762:11583890:1 gene:F12F6.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11578779-11583825(+) 100.0 100.0
Public Domain and Genome References
Gene Title MULTIPLE EXOSTOSES HOMOLOG 1
Gene Symbol rib-1
Ensembl F12F6.3
Entrez Gene 178080 Entrez gene
SwissProt O01704 EMBL-EBI
WormBase CE24898 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1583884_AT similar to Exostosin-1 (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1) cfa
CANINE_2:CFA.11712.1.A1_AT similar to Exostosin-1 (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1) cfa
CANINE_2:CFA.11712.1.A1_S_AT similar to Exostosin-1 (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1) cfa
DROSOPHILA_2:1637442_AT tout-velu dm
DROSGENOME1:153718_AT tout-velu dm
HG-U95AV2:222_AT exostoses (multiple) 1 hs
HC-G110:222_AT exostoses (multiple) 1 hs
HG-U133A:201995_AT exostoses (multiple) 1 hs
HG-U133_PLUS_2:201995_AT exostoses (multiple) 1 hs
HG-FOCUS:201995_AT exostoses (multiple) 1 hs
HG-U133A_2:201995_AT exostoses (multiple) 1 hs
HUGENEFL:S79639_AT exostoses (multiple) 1 hs
U133_X3P:G4557570_3P_AT exostoses (multiple) 1 hs
HG-U95AV2:32164_AT exostoses (multiple) 1 hs
HG-U133_PLUS_2:232174_AT Exostoses (multiple) 1 hs
HG-U133B:232174_AT Exostoses (multiple) 1 hs
HU35KSUBA:AA135370_AT Exostoses (multiple) 1 hs
HU35KSUBB:RC_N73878_AT Exostoses (multiple) 1 hs
HU35KSUBC:RC_AA081079_AT Exostoses (multiple) 1 hs
U133_X3P:HS2.351804.1.S1_3P_AT Exostoses (multiple) 1 hs
U133_X3P:HS2.33347.1.S1_3P_S_AT Exostoses (multiple) 1 hs
U133_X3P:HS2.306766.1.S1_3P_S_AT Exostoses (multiple) 1 hs
U133_X3P:HS.288700.0.S1_3P_AT Exostoses (multiple) 1 hs
U133_X3P:HS.188536.0.A1_3P_X_AT Exostoses (multiple) 1 hs
U133_X3P:HS.188536.0.A1_3P_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:1561056_A_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:1562863_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:1564378_A_AT Exostoses (multiple) 1 hs
HG-U133A_2:215206_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:215206_AT Exostoses (multiple) 1 hs
HG-U133A:215206_AT Exostoses (multiple) 1 hs
HG-U95B:42772_R_AT Exostoses (multiple) 1 hs
HG-U95B:45915_AT Exostoses (multiple) 1 hs
HG-U95E:80059_AT Exostoses (multiple) 1 hs
HG-U95E:85489_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:234634_AT Exostoses (multiple) 1 hs
HG-U133B:234634_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:237310_AT Exostoses (multiple) 1 hs
HG-U133B:237310_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:239227_AT Exostoses (multiple) 1 hs
HG-U133B:239227_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:239414_AT Exostoses (multiple) 1 hs
HG-U133B:239414_AT Exostoses (multiple) 1 hs
HG-U133_PLUS_2:242126_AT Exostoses (multiple) 1 hs
HG-U133B:242126_AT Exostoses (multiple) 1 hs
HG-U95B:46522_AT Exostoses (multiple) 1 hs
HG-U95B:53246_R_AT Exostoses (multiple) 1 hs
HG-U95E:67764_R_AT Exostoses (multiple) 1 hs
HG-U95D:78072_AT Exostoses (multiple) 1 hs
HG-U95D:87485_R_AT Exostoses (multiple) 1 hs
HG-U95D:87811_AT Exostoses (multiple) 1 hs
HG-U95D:89464_AT Exostoses (multiple) 1 hs
HU35KSUBB:RC_F04982_AT Exostoses (multiple) 1 hs
HU35KSUBB:RC_R08762_AT Exostoses (multiple) 1 hs
U133_X3P:HS.131793.0.A1_3P_AT Exostoses (multiple) 1 hs
U133_X3P:HS.187820.0.A1_3P_AT Exostoses (multiple) 1 hs
U133_X3P:HS.27319.0.S1_3P_AT Exostoses (multiple) 1 hs
U133_X3P:HS.285132.0.A1_3P_AT Exostoses (multiple) 1 hs
MU11KSUBB:X96639_S_AT exostoses (multiple) 1 mm
MG-U74AV2:102811_AT exostoses (multiple) 1 mm
MOE430A:1417730_AT exostoses (multiple) 1 mm
MOUSE430A_2:1417730_AT exostoses (multiple) 1 mm
MOUSE430_2:1417730_AT exostoses (multiple) 1 mm
MG-U74CV2:140833_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOE430B:1456655_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOUSE430_2:1456655_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOE430B:1440011_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOUSE430_2:1440011_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOE430B:1439877_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOUSE430_2:1439877_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOE430B:1440092_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOUSE430_2:1440092_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOUSE430_2:1458054_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOE430B:1458054_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOE430B:1458296_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
MOUSE430_2:1458296_AT Exostoses (multiple) 1, mRNA (cDNA clone MGC:5903 IMAGE:3499743) mm
RG-U34C:RC_AA858704_AT similar to Ext1 rn
RAE230A:1373393_AT similar to Ext1 rn
RAT230_2:1373393_AT similar to Ext1 rn
RAE230B:1382942_AT Similar to Ext1 rn
RAT230_2:1382942_AT Similar to Ext1 rn
RAE230B:1392083_AT Similar to Ext1 rn
RAT230_2:1392083_AT Similar to Ext1 rn
RG-U34C:RC_AI236163_AT Similar to Ext1 rn
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB61014 Hypothetical protein F12F6.3 [Caenorhabditis elegans] ref|NP_502180.1| related to mammalian RIB-affecting EXT gene family member (rib-1) [Caenorhabditis elegans] 0.0
blast O01704 Multiple exostoses homolog 1 (Related to mammalian RIB protein 1) gb|AAC47509.1| multiple exostoses homolog 1 [Caenorhabditis elegans] 0.0
blast T20803 hypothetical protein F12F6.3 - Caenorhabditis elegans 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR004263 EMBL-EBI Exostosin-like 1.4E-118
Sequence
Target Sequence 
>C. ELEGANS:175773_AT
aaaacattccttcatacatattcccataaggttcaatcccgatcttccgaacaacatccg
tgtcctcatcgcattagtactacccgagaaaggaaagggcggagtcgttgtgatgtctcg
agagcgtcggagaaagaacgtacacatacaaccatcgtctccttcatcatcatctccttc
ttgcgatcgatggcggcggtgcaggagacggaggggatggagagggtggggtgtctcact
cgttctcccctcatcacatctgctgctggctgtgatggctggttgcccctcttcttggcc
actctcttcacccacatccgtctcgttttgctctgtttgagattttcagcatcttccatt
tttatacatttct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAACATTCCTTCATACATATTCCC 110 131 1159 Antisense
ATTCCCATAAGGTTCAATCCCGATC 191 9 1178 Antisense
TCCTCATCGCATTAGTACTACCCGA 429 591 1221 Antisense
GGCGGAGTCGTTGTGATGTCTCGAG 613 539 1256 Antisense
ACGTACACATACAACCATCGTCTCC 356 95 1296 Antisense
TCATCTCCTTCTTGCGATCGATGGC 67 621 1328 Antisense
TGGAGAGGGTGGGGTGTCTCACTCG 210 549 1376 Antisense
TCATCACATCTGCTGCTGGCTGTGA 208 621 1409 Antisense
TGCTGGCTGTGATGGCTGGTTGCCC 667 581 1422 Antisense
CCGTCTCGTTTTGCTCTGTTTGAGA 337 265 1476 Antisense
GCATCTTCCATTTTTATACATTTCT 528 309 1507 Antisense
Sequence Source GenBank